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MTRHSYHHGDLPAVILAEAARLVAERGAERVSLRELARCAGVSHAAPAHHFTDRRGLFTALATQGFELLT RALADARGDFADAALAYVQFALDHPGHYQVMFNRSLLDASDGGLAAAEGAAGAELSRGVATLRDPHARAD PGGAELAAWSLVHGFATLWLNDAVDAAVRAADPMDTVRRIATMLFAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0728 | - | - | 100% (187) | TetR-family protein transcriptional regulator |
| M. avium 104 | MAV_4506 | - | 1e-07 | 26.63% (169) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4851 | - | 3e-05 | 27.03% (185) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0672c | - | 2e-07 | 32.26% (93) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1618 | - | 1e-67 | 69.19% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0653c | - | 2e-07 | 32.26% (93) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0499 | - | 5e-51 | 59.12% (181) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4906 | - | 1e-80 | 80.00% (185) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5838 | - | 1e-68 | 69.40% (183) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4347 | - | 2e-07 | 30.00% (170) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0500 | - | 3e-80 | 80.00% (185) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5135 | - | 2e-65 | 68.28% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4906|M.marinum_M -MNRPAYHHGDLRAVILDEAARLVAQRGADRVSMRELARDAGVSHAAPAH
MUL_0500|M.ulcerans_Agy99 -MNRPAYHHGDLRAVILDEAARLVAQRGADRVSMRELARDAGVSHAAPAH
MAV_0728|M.avium_104 -MTRHSYHHGDLPAVILAEAARLVAERGAERVSLRELARCAGVSHAAPAH
Mflv_1618|M.gilvum_PYR-GCK -MTRGSYHHGDLKAVILAQAATLVAERGADGVSLRELARAAGVSHAAPAH
Mvan_5135|M.vanbaalenii_PYR-1 MSSRGTYHHGDLRATILARAADLVAERGADGVSLRELARAAGVSHAAPAH
MSMEG_5838|M.smegmatis_MC2_155 ----MAYHHGDLKAVILQHAATLVAERGADGISLRELARTAGVSHAAPAH
MAB_0499|M.abscessus_ATCC_1997 ----MSYHHGDLRAAILTSAADMVARRGATELSLRELAREAGVSHAAPAH
Mb0672c|M.bovis_AF2122/97 -----MTSQTGVRDELLHAGVRLLDDHGPDALQTRKVAAAAGTSTMAVYT
Rv0653c|M.tuberculosis_H37Rv -----MTSQTGVRDELLHAGVRLLDDHGPDALQTRKVAAAAGTSTMAVYT
TH_4347|M.thermoresistible__bu ------VTADDIREKLVDAGVRLLERDGVQALSARNLAAEAGTSTMAVYT
.: :: .. :: * :. *::* **.* *
MMAR_4906|M.marinum_M HFTDRRGLFTALATQGFQLLAAALV------AARGHFADAALAYVRFAIE
MUL_0500|M.ulcerans_Agy99 HFTDRRGLFTALATQGFQLLAAALV------AARGHFADAALAYVRFAIE
MAV_0728|M.avium_104 HFTDRRGLFTALATQGFELLTRALA------DARGDFADAALAYVQFALD
Mflv_1618|M.gilvum_PYR-GCK HFTDRRGVFTALATQGWRMLAAALG------ESRPEFLDAALAYVRFAVD
Mvan_5135|M.vanbaalenii_PYR-1 HFTDRRGLFTALATEGFRSLAEELS------RARPEFLDAALAYVRFALA
MSMEG_5838|M.smegmatis_MC2_155 HFTDRRGLFTALATEGYQLLADALK------DVRGQFIDAAKAYVRFALD
MAB_0499|M.abscessus_ATCC_1997 HFGDRRGLFTALAADGFTRLADALD------GAHPDFHAAALAYVEFALA
Mb0672c|M.bovis_AF2122/97 HFGGMRGLIAAIAEEGLRQFDVALT-VPQTADPVADLLAIGTAYRRYAIE
Rv0653c|M.tuberculosis_H37Rv HFGGMRGLIAAIAEEGLRQFDVALT-VPQTADPVADLLAIGTAYRRYAIE
TH_4347|M.thermoresistible__bu RFGGMPGVLEAVAGEIFARFADALTQIPQTGDPVADFLLMGAAYREYALT
:* . *:: *:* : : * .: . ** .:*:
MMAR_4906|M.marinum_M HPGHYQVMFNRSLHDADD----ADLAAAQAAAAAELAAGVATLRDPGARS
MUL_0500|M.ulcerans_Agy99 HPGHYQVMFNRSLHDADD----ADLAAAQAAAAAELAAGVATLRDPGARF
MAV_0728|M.avium_104 HPGHYQVMFNRSLLDASD----GGLAAAEGAAGAELSRGVATLRDPHARA
Mflv_1618|M.gilvum_PYR-GCK HPGHYEVMFDRSLVDPDN----PELVAAQTEAGAELAAGVGTLDDARARE
Mvan_5135|M.vanbaalenii_PYR-1 NPGHYEVMFDKSLYHADD----PALVDAETAAGSELAAGVGTLDDPRAKD
MSMEG_5838|M.smegmatis_MC2_155 HPGHYAVMFDKSLYDDTD----PGLVAAASAAGAELNRGVGTLDDPKAKD
MAB_0499|M.abscessus_ATCC_1997 NPGHYSVMFEPALLDLAD----GRLAEARDRAAAALDSGIATLTPQQTSA
Mb0672c|M.bovis_AF2122/97 RPHMYRLMFGSTSAHGIN-VPARDVLTLKVAEIEHQHPSFAHVVRAVHRC
Rv0653c|M.tuberculosis_H37Rv RPHMYRLMFGSTSAHGIN-VPARDVLTLKVAEIEHQHPSFAHVVRAVHRC
TH_4347|M.thermoresistible__bu HPQRYLLMFGTATPASIAGSRADLTATGEVSDRTEWAASFEALRTMVRRM
.* * :** : .. :
MMAR_4906|M.marinum_M DPE----------------GAQLAAWSLVHGFSTLWLNDALDAQVRALDP
MUL_0500|M.ulcerans_Agy99 DPE----------------GAQLAAWSLVHGFSTLWLNDAFDAQVRALDP
MAV_0728|M.avium_104 DPG----------------GAELAAWSLVHGFATLWLNDAVDAAVRAADP
Mflv_1618|M.gilvum_PYR-GCK DPQ----------------AAGLAAWSLVHGFAMLWLNEAIDTDA---DA
Mvan_5135|M.vanbaalenii_PYR-1 DPQ----------------AAALAAWSLVHGFALLWLNGAVNTTG---DP
MSMEG_5838|M.smegmatis_MC2_155 DPA----------------GAALAAWSMVHGFSLLWLNDAIDTDR---DP
MAB_0499|M.abscessus_ATCC_1997 DRI----------------TAARAAWSLVHGFVSLWTTGALADSRDDADP
Mb0672c|M.bovis_AF2122/97 LLAGRFATALGADDDTAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEP
Rv0653c|M.tuberculosis_H37Rv LLAGRFATALGADDDTAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEP
TH_4347|M.thermoresistible__bu IAAGRIR-------DDGEAAIAGRLWSLIHGEVMLELAGFFGAEGHGLTK
** :** *
MMAR_4906|M.marinum_M MDTVLRIAMMLFKS------------------------------------
MUL_0500|M.ulcerans_Agy99 MDTVLRIAMMLFKASRSGCRRFGEGCRRDEGRHHQHHDNPENHRVGVGEI
MAV_0728|M.avium_104 MDTVRRIATMLFAG------------------------------------
Mflv_1618|M.gilvum_PYR-GCK VVTARRVARMLFTPGPVGDAGRG---------------------------
Mvan_5135|M.vanbaalenii_PYR-1 MATVRRVAGMLFGGEPVTCPT-----------------------------
MSMEG_5838|M.smegmatis_MC2_155 IATVERLGAILFDG------------------------------------
MAB_0499|M.abscessus_ATCC_1997 LRIASQIAYVLFPEAG----------------------------------
Mb0672c|M.bovis_AF2122/97 VLAAMTVNLLVALGDSPERAQCSLRAEQTQKNTLGRAT------------
Rv0653c|M.tuberculosis_H37Rv VLAAMTVNLLVALGDSPERAQCSLRAEQTQKNTLGRAT------------
TH_4347|M.thermoresistible__bu ILTPMTVDMLVGLGDDRARVEASL---TTAAEAHGR--------------
: : ::
MMAR_4906|M.marinum_M ---------------
MUL_0500|M.ulcerans_Agy99 MHHVVGEVGGEGLGR
MAV_0728|M.avium_104 ---------------
Mflv_1618|M.gilvum_PYR-GCK ---------------
Mvan_5135|M.vanbaalenii_PYR-1 ---------------
MSMEG_5838|M.smegmatis_MC2_155 ---------------
MAB_0499|M.abscessus_ATCC_1997 ---------------
Mb0672c|M.bovis_AF2122/97 ---------------
Rv0653c|M.tuberculosis_H37Rv ---------------
TH_4347|M.thermoresistible__bu ---------------