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MTTEIETGAAAETARRRSRMNADHPHYKWIVLSNTTLGTLLATINASIVLISLPAIFRGIGLNPLAPANI SYLLWMLMGYLVVTAVLVVPFGRLGDMFGRVRIYNVGFAVFTVAAIALSFDPFHLDGGAIWLIAWRVIQG IGGAMLMASSSAILTDAFPANQRGMALGVNMVAAVAGSFLGLLVGGVLSEWHWQAIFWVGVPIGLAGTVW SLRSLVEIGVRTPGRLDWAGTLTFGIGLTVLLIGITYGIQPYGGSTTGWTNPWVLGSIAAGLALLVVFCV VELRVAQPMVNVRLFRSAAFGMGNVAGLMSSMGRGGLQFMLIIWLQGIWLPLRGYDFEVTPLWAAIYMLP ITVGFLLAGPIAGWLSDRYGARPLTVGGMLLMAGSFIALVMIPVDFDYWVFAVLIFLNGVGGGIFTAPNT AAIMSSVPPSERGAASGVRATFFNAGSSLSIGIFFSLMVVGLANTLPGALSSGLQEQGVSADVAQQVADL PPVGSLFAAFLGYNPIAELLEPYHALQQPGVNAEVLTGQTFFPHLIIEPFHSGLVVVFVAAAIMMVIGMI ASMFNPGRYAEVVETP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0726 | - | - | 100% (576) | major facilitator superfamily transporter |
| M. vanbaalenii PYR-1 | Mvan_5021 | - | 9e-45 | 30.89% (437) | EmrB/QacA family drug resistance transporter |
| M. vanbaalenii PYR-1 | Mvan_4474 | - | 4e-42 | 27.93% (444) | EmrB/QacA family drug resistance transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1282 | - | 4e-41 | 27.10% (465) | drug-transport integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0301 | - | 3e-47 | 31.78% (472) | EmrB/QacA family drug resistance transporter |
| M. tuberculosis H37Rv | Rv1250 | - | 6e-41 | 27.10% (465) | drug-transport integral membrane protein |
| M. leprae Br4923 | MLBr_01562 | - | 3e-31 | 25.78% (419) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_4195c | - | 0.0 | 74.16% (565) | major facilitator superfamily |
| M. marinum M | MMAR_5192 | - | 2e-45 | 28.79% (455) | integral membrane transport protein |
| M. avium 104 | MAV_2104 | - | 0.0 | 80.56% (535) | major facilitator superfamily protein MFS_1 |
| M. smegmatis MC2 155 | MSMEG_0827 | - | 0.0 | 81.66% (567) | major facilitator superfamily protein MFS_1 |
| M. thermoresistible (build 8) | TH_2682 | - | 7e-52 | 31.99% (472) | PUTATIVE transmembrane efflux protein |
| M. ulcerans Agy99 | MUL_3590 | - | 2e-36 | 26.89% (502) | transmembrane transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0726|M.vanbaalenii_PYR-1 -------------------------MTTEIETGAAAETARRRSRMNADHP
MSMEG_0827|M.smegmatis_MC2_155 --------------------------MTEPADAALAETARRRKRMDHDHP
MAV_2104|M.avium_104 --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199 ---------------------MTDLITRVDETAADIETARRRVRVDRDHP
MMAR_5192|M.marinum_M -----------------------------MLTTLPTPPQTP----LVRRP
TH_2682|M.thermoresistible__bu -----------------------------MVDALSQPGQDIGASVAALST
Mb1282|M.bovis_AF2122/97 -----------------------------MTTAIRRAAGSS-------YF
Rv1250|M.tuberculosis_H37Rv -----------------------------MTTAIRRAAGSS-------YF
Mflv_0301|M.gilvum_PYR-GCK ------------------------------MTGLRMGTAAG---------
MUL_3590|M.ulcerans_Agy99 ---------------------------------MHLSAPAERSALTSRRQ
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mvan_0726|M.vanbaalenii_PYR-1 HYKWIVLSNTTLG--TLLATINASIVLISLPAIFRGIGLNPLAPANISYL
MSMEG_0827|M.smegmatis_MC2_155 FYKWIALSNTTLG--TLMATINASIVLISLPAIFRGIGLNPLDPANVSYL
MAV_2104|M.avium_104 ---------------MLLAMINSSIVLISLPAIFRGIGLNPLAPANIGYL
MAB_4195c|M.abscessus_ATCC_199 HYKWVALSNTTLG--VLLATINSSIVLISLPAIFRGIGLNPLAPGNVSYL
MMAR_5192|M.marinum_M GHQGLVLAVTCLA--LGTVVAAMASLNVALPDIARQTHAD------QTQQ
TH_2682|M.thermoresistible__bu RARVWLLTVACMG--VALVISSMVALNAALPDIAVETAAT------QSQL
Mb1282|M.bovis_AF2122/97 RNPWPALWAMMVG--FFMIMLDSTVVAIANPTIMAQLRIG------YATV
Rv1250|M.tuberculosis_H37Rv RNPWPALWAMMVG--FFMIMLDSTVVAIANPTIMAQLRIG------YATV
Mflv_0301|M.gilvum_PYR-GCK ---RWVLLATVLG--SGIVMVDATVVNVALPHIAADLGGG------FGDL
MUL_3590|M.ulcerans_Agy99 PSATAVLLVASFG--AFLAFLDSTIVNIAFPHIQRSFPSYD-----ISSL
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLS------DAGR
: * *
Mvan_0726|M.vanbaalenii_PYR-1 LWMLMGYLVVTAVLVVPFGRLGDMFGRVRIYNVGFAVFTVAAIALSFDPF
MSMEG_0827|M.smegmatis_MC2_155 LWMLMGYLVVTAVLVVLFGRLGDMYGRVRIYNIGFVVFTVAAVALSVDPF
MAV_2104|M.avium_104 LWMLMGYLVVTAVLVVFVGRLGDMFGRVRIYNAGFAVFTVAAIALSFDPF
MAB_4195c|M.abscessus_ATCC_199 LWMLMGYLLASAVLVVLFGRLGDMYGRVRIYNMGFVVFTVSAVVLSFDPF
MMAR_5192|M.marinum_M AWIVDAYSLVFASLLLPAGAVGDRYGRRLALLVGLVVFGAGSGVATLT--
TH_2682|M.thermoresistible__bu TWVVDGYTLVLACLLLPAGAIGDRYGRRGAMLVGLGLFTVASAAPLVL--
Mb1282|M.bovis_AF2122/97 VWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLS--
Rv1250|M.tuberculosis_H37Rv VWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLS--
Mflv_0301|M.gilvum_PYR-GCK QWVVNAYTLTLASLILLGGSLGDHFGRRKVFVLGVVWFALASIACGLAP-
MUL_3590|M.ulcerans_Agy99 SWILNGYNIVFAAFLVASGRLADVLGRKRMFVFGVVLFTIASGLCAVAG-
MLBr_01562|M.leprae_Br4923 SWGITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAW-
* .* :. . :: * :.* * *. * .: .
Mvan_0726|M.vanbaalenii_PYR-1 HLDGGAIWLIAWRVIQGIGGAMLMASSSAILTDAFP-ANQRGMALGVNMV
MSMEG_0827|M.smegmatis_MC2_155 HVGGGAVWLIAWRVVQGVGGAMLMASSSAILTDAFP-ANQRGMALGTNMV
MAV_2104|M.avium_104 PLTGGAVWLIGWRVVQGVGGAILMALSAAILTDAFP-SNQRGMALGFNMV
MAB_4195c|M.abscessus_ATCC_199 HYGGGAVWLIAWRVVQGVGGAMLMANSSAILTDAFP-STQRGLALGINQV
MMAR_5192|M.marinum_M ---TDPTALAGLRALLGVGAALIMPATLSTITSSFP-AQRRAAAVSIWTA
TH_2682|M.thermoresistible__bu ---DGPLTLILSRMVAGVGAAFVMPATLSLLTAAYP-RAQRNKAVGIWAA
Mb1282|M.bovis_AF2122/97 ---SGAGMLIAARVVQGVGAGLLTPQTLSTITRIFP-AHRRGVALGAWGT
Rv1250|M.tuberculosis_H37Rv ---SGAGMLIAARVVQGVGAGLLTPQTLSTITRIFP-AHRRGVALGAWGT
Mflv_0301|M.gilvum_PYR-GCK ----SIEVLIVARALQGVGGALLTPGSLALISAAFA-SGDRGAAVGAWSG
MUL_3590|M.ulcerans_Agy99 ----DVEQLVGFRVLQGIGAAVLVPASLALVVEGFD-ASHRAHAVGLWGA
MLBr_01562|M.leprae_Br4923 ----DEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAA
. * * : *:*... . : : : * * .
Mvan_0726|M.vanbaalenii_PYR-1 AAVAGSFLGLLVGG-VLSEWHWQAIFWVGVPIGLAGTVWSLRSLVEIGVR
MSMEG_0827|M.smegmatis_MC2_155 SAVAGSFLGLLIGG-VLSEWDWRAIFWVGVPVGILGTVWSYRSLKELGVR
MAV_2104|M.avium_104 AAVAGSFLGLLFGG-LLSEWDWRAIFWVGVPVGVLGTVWGMRSLHELGVR
MAB_4195c|M.abscessus_ATCC_199 AAVAGSFLGLLIGG-VLSEWDWRAIFWVGVPLGLLGTVWSYRSLVEIDQP
MMAR_5192|M.marinum_M VAGASGVVGLLASGLLLQWWSWQSIFWLNVLLAAVALTGTLLFVPESAER
TH_2682|M.thermoresistible__bu VAGSGAVVGFLGTGVLLHFWSWPSIFWA-FTVSGAGLFVLACTVASSRDH
Mb1282|M.bovis_AF2122/97 VASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP-ALPH
Rv1250|M.tuberculosis_H37Rv VASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP-ALPH
Mflv_0301|M.gilvum_PYR-GCK LGGIAGAIGPFLGG-ALVEWNWRAAFLINVPLAAFVIAVTLLRVPESRDP
MUL_3590|M.ulcerans_Agy99 AAAVASGLGPPVGGMLVEASSWRLVFLVNIPLGIVAVLVAGRVLTESRAS
MLBr_01562|M.leprae_Br4923 MTAIGSVMGLVVGG-ALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKE
.. :* * : * * . :. :
Mvan_0726|M.vanbaalenii_PYR-1 TPGR-LDWAGTLTFGIGLTVLLIGITYGIQPYGGSTTGWTNPWVLGSIAA
MSMEG_0827|M.smegmatis_MC2_155 TPGK-LDWAGTLTFGIGLTVLLTGITYGIQPYGDSTTGWTSPFVLGAIVA
MAV_2104|M.avium_104 TPGP-LDWPGTVTFGVGLTVVLVGITYGIQPYGGHPTGWTNPWVLGSIAF
MAB_4195c|M.abscessus_ATCC_199 TPGK-LDWAGTVTVALGLTVLLTGITYGIQPYGNASTGWSNPLVYGSLIA
MMAR_5192|M.marinum_M DPAP-LDVVGAVLAAAGIAVLVYAVIE------APAYGWTDPVTVGGIAV
TH_2682|M.thermoresistible__bu RATP-LDWPGAVLIGGAVAVFVYGVLE------APVHGWTHPVVYGSMAA
Mb1282|M.bovis_AF2122/97 HPHR-FDWFGVGLSGAGMFLIVFGLQQ------GQSANW-QPWIWAVIVG
Rv1250|M.tuberculosis_H37Rv HPHR-FDWFGVGLSGAGMFLIVFGLQQ------GQSANW-QPWIWAVIVG
Mflv_0301|M.gilvum_PYR-GCK SASRRLDVGGAVLTVVGLGALTFGLTELG-------NRGASPAAVVSVGG
MUL_3590|M.ulcerans_Agy99 GRRRVPDLRGAMLLGVALGLMTLGLVK------GPEWGWISTATIGSFVA
MLBr_01562|M.leprae_Br4923 RMKL--DAAGAILATLACTAAVFAFSMG------PEKGWISLTTIGSGLV
* *. . ..
Mvan_0726|M.vanbaalenii_PYR-1 GLALLVVFCVVELR-VAQPMVNVRLFRSAAFGMGNVAGLMSSMGRGGLQF
MSMEG_0827|M.smegmatis_MC2_155 GLGLLIAFCLIELR-VPNPMMNIRLFRSTAFGMGNLAGLMSSVGRGGLQF
MAV_2104|M.avium_104 GLLLLIVFCFIELR-APQPMVNVRLFRSAGFGMGNLANLMSSSGRGGLQF
MAB_4195c|M.abscessus_ATCC_199 GVALLVLFCVIEAR-VADPMLDIRLFKNRAFGLGNLANLLASVGRGGLQF
MMAR_5192|M.marinum_M GLLILAGFVVIEMG-RRYPLLDPRLFTNRRFAAGSLSITLQFFALFGFLF
TH_2682|M.thermoresistible__bu GVALALAFAVVELR-SAHPLLDIRLFAKPDFTTGAVGVTFFFLANFGFFF
Mb1282|M.bovis_AF2122/97 GIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLGIAIIAFAGTGMML
Rv1250|M.tuberculosis_H37Rv GIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMML
Mflv_0301|M.gilvum_PYR-GCK GLVALVVFVLVEQR-SSHPLMSPKLFADRNFGVANAVTLLIYGALGAVFL
MUL_3590|M.ulcerans_Agy99 SSVALVAFVASSRS-HPTPLIDPAFLRVRSFVAGNLLTLVAAAGFYCYVL
MLBr_01562|M.leprae_Br4923 ALVAAIAFAVVERT-AENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTV
. * . *:: .: . .
Mvan_0726|M.vanbaalenii_PYR-1 MLIIWLQGIWLPLRGYDFEVTPLWAAIYMLPITVGFLLAGPIAGWLSDRY
MSMEG_0827|M.smegmatis_MC2_155 MLIIWLQGIWLPLHGYSFESTPLWAGIYMLPMTIGFLVSGPLAGSLSDRF
MAV_2104|M.avium_104 MLIIWLQGIWLPLHGYRFESTPLWAGIYMLPTTIGFLIAAPVAGWLADRF
MAB_4195c|M.abscessus_ATCC_199 MLIIWLQGIWLPLRGYSYESTPLWAGIFLLPMTLGFLVAGPVAGLLSDRY
MMAR_5192|M.marinum_M VIMQYLQSVRH--------YSALTAALGLLAMPIGMIPSSRLSPYLTERF
TH_2682|M.thermoresistible__bu VSMQYMQLMLG--------YSALQTAFALTPLTIPLLLLSVTTQWYLPRL
Mb1282|M.bovis_AF2122/97 PVTFYAQAVCG--------LSPTHTAVLFAPTAIVGGVLAPFVGMIIDRS
Rv1250|M.tuberculosis_H37Rv PVTFYAQAVCG--------LSPTHTAVLFAPTAIVGGVLAPFVGMIIDRS
Mflv_0301|M.gilvum_PYR-GCK LLVLQLQTVSG--------FSPVAAGTALLPFTIVMLLFSSRAGALSGRI
MUL_3590|M.ulcerans_Agy99 THVLYLNYVWH--------YSLLKAGFAIAPAALIAAVVAAVLGRIADQR
MLBr_01562|M.leprae_Br4923 SIGLYIQDILG--------YSALRAGIGFIPFVIAMGIGLGVSSQLVSRF
: : : :. : . : :
Mvan_0726|M.vanbaalenii_PYR-1 GARPLTVGGMLLMAGSF-IALVMIPVDFDYWVFAVL-IFLNGVGGGIFTA
MSMEG_0827|M.smegmatis_MC2_155 GARPFTVGGMVIMAATF-VALVMIPVDFDYWLFAVL-VFLNGLGGGIFTA
MAV_2104|M.avium_104 GARPFAVAGMLLMAVTF-IGLLMIPVNFDYRVFALL-IFLNALGGGLFAA
MAB_4195c|M.abscessus_ATCC_199 GARPFATGGMVLSAVTF-LALIAIPVNFNYWVFALL-IFLNGLGSAIFTA
MMAR_5192|M.marinum_M GIRLPWVAGLLIVAEGL-MVLAHLDSADPYWHIASG-LIPLGAGLGLAMP
TH_2682|M.thermoresistible__bu GLRAVISTGLLLIAAGL-FYARTLEIASPYLDLAVP-LLIMSTGIGLCTA
Mb1282|M.bovis_AF2122/97 HPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLP-FIALGVAGAFVWS
Rv1250|M.tuberculosis_H37Rv HPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLP-FIALGVAGAFVWS
Mflv_0301|M.gilvum_PYR-GCK GPRLPMTVGPVLAGLGLLLMLRIGEDASWVFDVAPA-ALVFGAGMVLVVA
MUL_3590|M.ulcerans_Agy99 GHRLVVMAGAIIWAGSLVWYLQRVGTEPNFLREWLPGQLLQGIGVGATLP
MLBr_01562|M.leprae_Br4923 SPRVLTIGGGWLLMVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVV
* : : . . .
Mvan_0726|M.vanbaalenii_PYR-1 PNTAAIMSSVPPS-ERGAASGVRATFFNAGSSLSIGIFFSLMVVG-----
MSMEG_0827|M.smegmatis_MC2_155 PNSAAVMSAVPAG-ERGAASGVRATFFNAGSSLSIGIFFSLMIVG-----
MAV_2104|M.avium_104 PNTAVIMSSVPPR-DRGAASGVRSTFFNAGSALSIGVFFSLMVVG-----
MAB_4195c|M.abscessus_ATCC_199 PNTAAIMSSVPAH-QRGAASGVRGTFFNAGSSLSIGIFFSLMIVG-----
MMAR_5192|M.marinum_M PATTAITGALPSR-LQNVGSAVNDLARELGGALGIAVLGSLLTAT-----
TH_2682|M.thermoresistible__bu PSTSAIMGAVPDE-KHGVASAVNDTTREIGAALGIAVAGSVLAAE-----
Mb1282|M.bovis_AF2122/97 PLTVTATRNLRPH-LAGASSGVFNAVRQLGAVLGSASMAAFMTSR-----
Rv1250|M.tuberculosis_H37Rv PLTVTATRNLRPH-LAGASSGVFNAVRQLGAVLGSASMAAFMTSR-----
Mflv_0301|M.gilvum_PYR-GCK PLTATVLDAAPEH-MAGSASGVNNAVARAGGLLAVAVLPGVAGISGN---
MUL_3590|M.ulcerans_Agy99 VLGSAALAGLTKGGSYATASAVVSTTRQLGAVIGVALLVILIGKPAPGTG
MLBr_01562|M.leprae_Br4923 PLTLSAIAGVGFD-RIGPVSAIALMLQSLGGPLVLAVIQAVITSR-----
*.: *. : . .
Mvan_0726|M.vanbaalenii_PYR-1 --------------------LANTLP---------GALSSGLQEQGVSAD
MSMEG_0827|M.smegmatis_MC2_155 --------------------LAGTLP---------TAMSAGLEQQGVSAS
MAV_2104|M.avium_104 --------------------LAGTLP---------HALSSGLQQQGVPAA
MAB_4195c|M.abscessus_ATCC_199 --------------------LSATMP---------AAMQSGLTVQGVPAS
MMAR_5192|M.marinum_M --------------------YRNHLPTAGAVSAFCTGLHVSLTGAALTIV
TH_2682|M.thermoresistible__bu --------------------YGDRLR------PHLGALPEPVRQAASNSL
Mb1282|M.bovis_AF2122/97 --------------------IAAEMP---------GGVDALTGPAGQDAT
Rv1250|M.tuberculosis_H37Rv --------------------IAAEMP---------GGVDALTGPAGQDAT
Mflv_0301|M.gilvum_PYR-GCK ------------------DYADP------------AAFSAGFHTAVVISA
MUL_3590|M.ulcerans_Agy99 VEALRHGWVLAAVCFAAVAVLAGFLGRTQQGADVAGAPESGVARAPARPQ
MLBr_01562|M.leprae_Br4923 ------------------------------------TLYLGGTTGPVKFM
Mvan_0726|M.vanbaalenii_PYR-1 VAQQVADLP-------------------PVGSLFAAFLGYN---------
MSMEG_0827|M.smegmatis_MC2_155 VAHEVANLP-------------------PVGSLFAAFLGYN---------
MAV_2104|M.avium_104 VAQDAAALP-------------------PVGSLFAAFLGYN---------
MAB_4195c|M.abscessus_ATCC_199 TAAQVSSLP-------------------PVGSLFAAFLGYN---------
MMAR_5192|M.marinum_M ATAIAVAALLRRPHRPGRHRRSRSAWRGQQRARAGFTAASDPKRVELFQQ
TH_2682|M.thermoresistible__bu AEALEAARQL-----------------GPQGARLAEFAQS----------
Mb1282|M.bovis_AF2122/97 VLQLPEFVR------------------EPFAAAMSQSMLLP---------
Rv1250|M.tuberculosis_H37Rv VLQLPEFVR------------------EPFAAAMSQSMLLP---------
Mflv_0301|M.gilvum_PYR-GCK VLMVAAAVL-----------------------------------------
MUL_3590|M.ulcerans_Agy99 PVTPRPAAAPARPPQTTADGDLLRQLPLFAGLPAATMAELRHHTDEIELQ
MLBr_01562|M.leprae_Br4923 NDAQLRALDHG---------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1 -----------------------------------PIAELLEPYHALQQP
MSMEG_0827|M.smegmatis_MC2_155 -----------------------------------PIAELLAPFHALQQP
MAV_2104|M.avium_104 -----------------------------------PIAELLAPSHALQQP
MAB_4195c|M.abscessus_ATCC_199 -----------------------------------PVGELLAPSGVLEQP
MMAR_5192|M.marinum_M R-----HRDPAGGSQDPARLAHRERLGQCREDLGRPLERVRTEHDRVGDP
TH_2682|M.thermoresistible__bu --------------------AFLEAMHVSLIVLG-ALCALAAAFVAVWAP
Mb1282|M.bovis_AF2122/97 --------------------AFVALFGIVAALFLVDFTGAAVAKEPLPES
Rv1250|M.tuberculosis_H37Rv --------------------AFVALFGIVAALFLVDFTGAAVAKEPLPES
Mflv_0301|M.gilvum_PYR-GCK -----------------------------------------AAIGIRRAP
MUL_3590|M.ulcerans_Agy99 AGSYLFHEVDPSDALYVVRSGRLRVVQRDLVLRELGRGEVVGELGLLIDA
MLBr_01562|M.leprae_Br4923 -----------------------------------------YTYGLLWVA
.
Mvan_0726|M.vanbaalenii_PYR-1 GVNAEVLTG---------------------------------QTFFPHLI
MSMEG_0827|M.smegmatis_MC2_155 GVNADVLTG---------------------------------QQFFPQLI
MAV_2104|M.avium_104 GVNAATLTG---------------------------------KSFFPELI
MAB_4195c|M.abscessus_ATCC_199 GVNTAELTG---------------------------------QSFFPNLI
MMAR_5192|M.marinum_M GQPAGAYRRGQLTRT-----------------------EPQLTQFVGFRG
TH_2682|M.thermoresistible__bu GRDGRQYG------------------------------------FV-ERW
Mb1282|M.bovis_AF2122/97 DGDADDDD---------------------------------YVEYILRRE
Rv1250|M.tuberculosis_H37Rv DGDADDDD---------------------------------YVEYILRRE
Mflv_0301|M.gilvum_PYR-GCK ARSD-------------------------------------------ERM
MUL_3590|M.ulcerans_Agy99 PRSASVQAMRDFVLIRLSKAQFNRIADRGVLAALVGTLATRLHTAPPPTV
MLBr_01562|M.leprae_Br4923 GAVVIVGVA---------------------------------------AL
Mvan_0726|M.vanbaalenii_PYR-1 IEPFHSGLVVVFVAAAIMMVIGMIASMFNPGRYAEVVETP----------
MSMEG_0827|M.smegmatis_MC2_155 TAPFHAGVTVVFIAAAVMMVIGAIASMFNAGRYGTEAGADNEA-------
MAV_2104|M.avium_104 SGPFHAGLVVVFVAAALMMVTGALASLVNPGRYADDVEEI----------
MAB_4195c|M.abscessus_ATCC_199 TEPFHAGLVVVFGAAALMMAVAALASLGAGGKYAHADD------------
MMAR_5192|M.marinum_M AKRFGGQPSFEGAHRRVDPRWQARAG----RSHQPVGHVQPGSHQQRGNQ
TH_2682|M.thermoresistible__bu TSRWSGEEAGGAVAEHDDGGVRAATG----DGWEHGTVDDP---------
Mb1282|M.bovis_AF2122/97 PEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAW
Rv1250|M.tuberculosis_H37Rv PEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAW
Mflv_0301|M.gilvum_PYR-GCK AVENCTHCAITGLPAHPAAETR----------------------------
MUL_3590|M.ulcerans_Agy99 DRPASPEAVIAVIGLGAAVPVRPVALALLNALSARVTAVDPGRVDRAGLE
MLBr_01562|M.leprae_Br4923 FIGYTPEQVAYAQEVKEAVDAGEL--------------------------
Mvan_0726|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0827|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2104|M.avium_104 --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5192|M.marinum_M LGGG----------------------------------------------
TH_2682|M.thermoresistible__bu --------------------------------------------------
Mb1282|M.bovis_AF2122/97 QADTESTAPSAL--------------------------------------
Rv1250|M.tuberculosis_H37Rv QADTESTAPSAL--------------------------------------
Mflv_0301|M.gilvum_PYR-GCK --------------------------------------------------
MUL_3590|M.ulcerans_Agy99 RAEASADKVVLDASANDTGWRDFCLRAADRIVLVSEGPAPRDTQLPARAV
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0827|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2104|M.avium_104 --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5192|M.marinum_M --------------------------------------------------
TH_2682|M.thermoresistible__bu --------------------------------------------------
Mb1282|M.bovis_AF2122/97 --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK --------------------------------------------------
MUL_3590|M.ulcerans_Agy99 GADLVLIGAPASQEDRSRWEELIPPRSVHSVSYRSLKDDVRPLAARITGG
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0827|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2104|M.avium_104 --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5192|M.marinum_M --------------------------------------------------
TH_2682|M.thermoresistible__bu --------------------------------------------------
Mb1282|M.bovis_AF2122/97 --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK --------------------------------------------------
MUL_3590|M.ulcerans_Agy99 SIGLVLGGGGARAFAHLGVLDELEAAGIVVDRFAGTSMGAVIAALAASGL
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0827|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2104|M.avium_104 --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5192|M.marinum_M --------------------------------------------------
TH_2682|M.thermoresistible__bu --------------------------------------------------
Mb1282|M.bovis_AF2122/97 --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK --------------------------------------------------
MUL_3590|M.ulcerans_Agy99 DAAGVDAHVFEYLVRHNPLGDYTLPSKGLVRGRRTMGLLREAYSGRMVEE
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0827|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2104|M.avium_104 --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5192|M.marinum_M --------------------------------------------------
TH_2682|M.thermoresistible__bu --------------------------------------------------
Mb1282|M.bovis_AF2122/97 --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK --------------------------------------------------
MUL_3590|M.ulcerans_Agy99 LPKEFRCVSVDLLARQAVVHRRGPVAEVVGCSLRVPGLYPPQIYNGQLHV
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0827|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2104|M.avium_104 --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5192|M.marinum_M --------------------------------------------------
TH_2682|M.thermoresistible__bu --------------------------------------------------
Mb1282|M.bovis_AF2122/97 --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK --------------------------------------------------
MUL_3590|M.ulcerans_Agy99 DGGVLNNLPVTALTRAEGPMIAVSVGFGGNPSGGQPRRSGPIQVPGIGDT
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0827|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2104|M.avium_104 --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5192|M.marinum_M --------------------------------------------------
TH_2682|M.thermoresistible__bu --------------------------------------------------
Mb1282|M.bovis_AF2122/97 --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK --------------------------------------------------
MUL_3590|M.ulcerans_Agy99 LMRTMMMGSRTVADAAQAEALVVIRPDTRAVGLLEFHQIDAAREAGRAAA
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1 ---------------------------------------
MSMEG_0827|M.smegmatis_MC2_155 ---------------------------------------
MAV_2104|M.avium_104 ---------------------------------------
MAB_4195c|M.abscessus_ATCC_199 ---------------------------------------
MMAR_5192|M.marinum_M ---------------------------------------
TH_2682|M.thermoresistible__bu ---------------------------------------
Mb1282|M.bovis_AF2122/97 ---------------------------------------
Rv1250|M.tuberculosis_H37Rv ---------------------------------------
Mflv_0301|M.gilvum_PYR-GCK ---------------------------------------
MUL_3590|M.ulcerans_Agy99 RAALPQIIPLLRSGPAGQTTGRAIDRSARALRTDARRPA
MLBr_01562|M.leprae_Br4923 ---------------------------------------