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M. avium 104 MAV_2104 (-)

annotation: major facilitator superfamily protein MFS_1
coordinates: 2105517 - 2107133
length: 538

LLAMINSSIVLISLPAIFRGIGLNPLAPANIGYLLWMLMGYLVVTAVLVVFVGRLGDMFGRVRIYNAGFA
VFTVAAIALSFDPFPLTGGAVWLIGWRVVQGVGGAILMALSAAILTDAFPSNQRGMALGFNMVAAVAGSF
LGLLFGGLLSEWDWRAIFWVGVPVGVLGTVWGMRSLHELGVRTPGPLDWPGTVTFGVGLTVVLVGITYGI
QPYGGHPTGWTNPWVLGSIAFGLLLLIVFCFIELRAPQPMVNVRLFRSAGFGMGNLANLMSSSGRGGLQF
MLIIWLQGIWLPLHGYRFESTPLWAGIYMLPTTIGFLIAAPVAGWLADRFGARPFAVAGMLLMAVTFIGL
LMIPVNFDYRVFALLIFLNALGGGLFAAPNTAVIMSSVPPRDRGAASGVRSTFFNAGSALSIGVFFSLMV
VGLAGTLPHALSSGLQQQGVPAAVAQDAAALPPVGSLFAAFLGYNPIAELLAPSHALQQPGVNAATLTGK
SFFPELISGPFHAGLVVVFVAAALMMVTGALASLVNPGRYADDVEEI*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2104--100% (538)major facilitator superfamily protein MFS_1
M. avium 104MAV_2832-1e-3926.54% (456) drug transporter
M. avium 104MAV_1387-3e-3827.96% (490) drug transporter

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1282-7e-4128.57% (455) drug-transport integral membrane protein
M. gilvum PYR-GCKMflv_0301-8e-4530.87% (460) EmrB/QacA family drug resistance transporter
M. tuberculosis H37RvRv1250-9e-4128.57% (455) drug-transport integral membrane protein
M. leprae Br4923MLBr_01562-1e-2926.10% (479) putative transmembrane efflux protein
M. abscessus ATCC 19977MAB_4195c-0.073.12% (532) major facilitator superfamily
M. marinum MMMAR_3642-1e-3928.57% (469) integral membrane transport protein
M. smegmatis MC2 155MSMEG_0827-0.077.67% (533) major facilitator superfamily protein MFS_1
M. thermoresistible (build 8)TH_2682-1e-4629.85% (536) PUTATIVE transmembrane efflux protein
M. ulcerans Agy99MUL_3590-1e-3528.24% (471) transmembrane transport protein
M. vanbaalenii PYR-1Mvan_0726-0.080.56% (535) major facilitator superfamily transporter

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0827|M.smegmatis_MC2_155      --------------------------MTEPADAALAETARRRKRMDHDHP
Mvan_0726|M.vanbaalenii_PYR-1       -------------------------MTTEIETGAAAETARRRSRMNADHP
MAV_2104|M.avium_104                --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      ---------------------MTDLITRVDETAADIETARRRVRVDRDHP
Mb1282|M.bovis_AF2122/97            ------------------------------------MTTAIRRAAGSSYF
Rv1250|M.tuberculosis_H37Rv         ------------------------------------MTTAIRRAAGSSYF
Mflv_0301|M.gilvum_PYR-GCK          -------------------------------------MTGLRMGTAAG--
MMAR_3642|M.marinum_M               ------------------------------------------------MN
TH_2682|M.thermoresistible__bu      -----------------------------MVDALSQPGQDIGASVAALST
MUL_3590|M.ulcerans_Agy99           ---------------------------------MHLSAPAERSALTSRRQ
MLBr_01562|M.leprae_Br4923          MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      FYKWIALSNTTLG--TLMATINASIVLISLPAIFRGIGLNPLDPANVSYL
Mvan_0726|M.vanbaalenii_PYR-1       HYKWIVLSNTTLG--TLLATINASIVLISLPAIFRGIGLNPLAPANISYL
MAV_2104|M.avium_104                ---------------MLLAMINSSIVLISLPAIFRGIGLNPLAPANIGYL
MAB_4195c|M.abscessus_ATCC_199      HYKWVALSNTTLG--VLLATINSSIVLISLPAIFRGIGLNPLAPGNVSYL
Mb1282|M.bovis_AF2122/97            RNPWPALWAMMVG--FFMIMLDSTVVAIANPTIMAQLRIG------YATV
Rv1250|M.tuberculosis_H37Rv         RNPWPALWAMMVG--FFMIMLDSTVVAIANPTIMAQLRIG------YATV
Mflv_0301|M.gilvum_PYR-GCK          ---RWVLLATVLG--SGIVMVDATVVNVALPHIAADLGGG------FGDL
MMAR_3642|M.marinum_M               RTQLLTIFATGLG--LFMIFLDAFIVNVALPDIQNTFGVG------EDGL
TH_2682|M.thermoresistible__bu      RARVWLLTVACMG--VALVISSMVALNAALPDIAVETAAT------QSQL
MUL_3590|M.ulcerans_Agy99           PSATAVLLVASFG--AFLAFLDSTIVNIAFPHIQRSFPSYD-----ISSL
MLBr_01562|M.leprae_Br4923          PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLS------DAGR
                                                     :   .      : * *                 

MSMEG_0827|M.smegmatis_MC2_155      LWMLMGYLVVTAVLVVLFGRLGDMYGRVRIYNIGFVVFTVAAVALSVDPF
Mvan_0726|M.vanbaalenii_PYR-1       LWMLMGYLVVTAVLVVPFGRLGDMFGRVRIYNVGFAVFTVAAIALSFDPF
MAV_2104|M.avium_104                LWMLMGYLVVTAVLVVFVGRLGDMFGRVRIYNAGFAVFTVAAIALSFDPF
MAB_4195c|M.abscessus_ATCC_199      LWMLMGYLLASAVLVVLFGRLGDMYGRVRIYNMGFVVFTVSAVVLSFDPF
Mb1282|M.bovis_AF2122/97            VWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLS--
Rv1250|M.tuberculosis_H37Rv         VWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLS--
Mflv_0301|M.gilvum_PYR-GCK          QWVVNAYTLTLASLILLGGSLGDHFGRRKVFVLGVVWFALASIACGLAP-
MMAR_3642|M.marinum_M               QWVVAAYSLGMAVFIMSAATLADRYGRRRWYLMGIALFTLGSIACGLAP-
TH_2682|M.thermoresistible__bu      TWVVDGYTLVLACLLLPAGAIGDRYGRRGAMLVGLGLFTVASAAPLVLD-
MUL_3590|M.ulcerans_Agy99           SWILNGYNIVFAAFLVASGRLADVLGRKRMFVFGVVLFTIASGLCAVAG-
MLBr_01562|M.leprae_Br4923          SWGITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAW-
                                     *   .* :  .  ::  . :.*  *       *.  *::.:    .   

MSMEG_0827|M.smegmatis_MC2_155      HVGGGAVWLIAWRVVQGVGGAMLMASSSAILTDAFPA-NQRGMALGTNMV
Mvan_0726|M.vanbaalenii_PYR-1       HLDGGAIWLIAWRVIQGIGGAMLMASSSAILTDAFPA-NQRGMALGVNMV
MAV_2104|M.avium_104                PLTGGAVWLIGWRVVQGVGGAILMALSAAILTDAFPS-NQRGMALGFNMV
MAB_4195c|M.abscessus_ATCC_199      HYGGGAVWLIAWRVVQGVGGAMLMANSSAILTDAFPS-TQRGLALGINQV
Mb1282|M.bovis_AF2122/97            ---SGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPA-HRRGVALGAWGT
Rv1250|M.tuberculosis_H37Rv         ---SGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPA-HRRGVALGAWGT
Mflv_0301|M.gilvum_PYR-GCK          ----SIEVLIVARALQGVGGALLTPGSLALISAAFAS-GDRGAAVGAWSG
MMAR_3642|M.marinum_M               ----SIAMLTAARGIQGFGAATVSVTSLALVSAAFPNPKEKARAIGIWTA
TH_2682|M.thermoresistible__bu      ----GPLTLILSRMVAGVGAAFVMPATLSLLTAAYPR-AQRNKAVGIWAA
MUL_3590|M.ulcerans_Agy99           ----DVEQLVGFRVLQGIGAAVLVPASLALVVEGFDA-SHRAHAVGLWGA
MLBr_01562|M.leprae_Br4923          ----DEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAA
                                        .   *   * : *.*..       : :   :     :  * .    

MSMEG_0827|M.smegmatis_MC2_155      SAVAGSFLGLLIG-GVLSEWDWRAIFWVGVPVGILGTVWSYRSLKELGVR
Mvan_0726|M.vanbaalenii_PYR-1       AAVAGSFLGLLVG-GVLSEWHWQAIFWVGVPIGLAGTVWSLRSLVEIGVR
MAV_2104|M.avium_104                AAVAGSFLGLLFG-GLLSEWDWRAIFWVGVPVGVLGTVWGMRSLHELGVR
MAB_4195c|M.abscessus_ATCC_199      AAVAGSFLGLLIG-GVLSEWDWRAIFWVGVPLGLLGTVWSYRSLVEIDQP
Mb1282|M.bovis_AF2122/97            VASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPH-
Rv1250|M.tuberculosis_H37Rv         VASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPH-
Mflv_0301|M.gilvum_PYR-GCK          LGGIAGAIGPFLG-GALVEWNWRAAFLINVPLAAFVIAVTLLRVPESRDP
MMAR_3642|M.marinum_M               VASVGTATGPTLGGLLVDTWGWRSIFYVNVPMGVFVILLTVGFVAESRNA
TH_2682|M.thermoresistible__bu      VAGSGAVVGFLGTGVLLHFWSWPSIFWAFTVSGAGLFVLACTVASSRDHR
MUL_3590|M.ulcerans_Agy99           AAAVASGLGPPVGGMLVEASSWRLVFLVNIPLGIVAVLVAGRVLTESRAS
MLBr_01562|M.leprae_Br4923          MTAIGSVMGLVVG-GALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKE
                                        .   *       :    *   *      .                 

MSMEG_0827|M.smegmatis_MC2_155      -TPGKLDWAGTLTFGIGLTVLLTGITYGIQPYGDSTTGWTSPFVLGAIVA
Mvan_0726|M.vanbaalenii_PYR-1       -TPGRLDWAGTLTFGIGLTVLLIGITYGIQPYGGSTTGWTNPWVLGSIAA
MAV_2104|M.avium_104                -TPGPLDWPGTVTFGVGLTVVLVGITYGIQPYGGHPTGWTNPWVLGSIAF
MAB_4195c|M.abscessus_ATCC_199      -TPGKLDWAGTVTVALGLTVLLTGITYGIQPYGNASTGWSNPLVYGSLIA
Mb1282|M.bovis_AF2122/97            -HPHRFDWFGVGLSGAGMFLIVFGLQQ------GQSANWQ-PWIWAVIVG
Rv1250|M.tuberculosis_H37Rv         -HPHRFDWFGVGLSGAGMFLIVFGLQQ------GQSANWQ-PWIWAVIVG
Mflv_0301|M.gilvum_PYR-GCK          SASRRLDVGGAVLTVVGLGALTFGLTELG-------NRGASPAAVVSVGG
MMAR_3642|M.marinum_M               -RAGRLDLSGQALFIVTVGAFVYAVIE------GPQIGWTSPLILTLLMT
TH_2682|M.thermoresistible__bu      --ATPLDWPGAVLIGGAVAVFVYGVLEAP------VHGWTHPVVYGSMAA
MUL_3590|M.ulcerans_Agy99           GRRRVPDLRGAMLLGVALGLMTLGLVK------GPEWGWISTATIGSFVA
MLBr_01562|M.leprae_Br4923          --RMKLDAAGAILATLACTAAVFAFSMG------PEKGWISLTTIGSGLV
                                          *  *             ..                         

MSMEG_0827|M.smegmatis_MC2_155      GLGLLIAFCLIELR-VPNPMMNIRLFRSTAFGMGNLAGLMSSVGRGGLQF
Mvan_0726|M.vanbaalenii_PYR-1       GLALLVVFCVVELR-VAQPMVNVRLFRSAAFGMGNVAGLMSSMGRGGLQF
MAV_2104|M.avium_104                GLLLLIVFCFIELR-APQPMVNVRLFRSAGFGMGNLANLMSSSGRGGLQF
MAB_4195c|M.abscessus_ATCC_199      GVALLVLFCVIEAR-VADPMLDIRLFKNRAFGLGNLANLLASVGRGGLQF
Mb1282|M.bovis_AF2122/97            GIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLGIAIIAFAGTGMML
Rv1250|M.tuberculosis_H37Rv         GIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMML
Mflv_0301|M.gilvum_PYR-GCK          GLVALVVFVLVEQR-SSHPLMSPKLFADRNFGVANAVTLLIYGALGAVFL
MMAR_3642|M.marinum_M               AAVGCALFLWLEGR-SADPMMDLTLFRDSSYALSIGTICTVFFAVYGMLL
TH_2682|M.thermoresistible__bu      GVALALAFAVVELR-SAHPLLDIRLFAKPDFTTGAVGVTFFFLANFGFFF
MUL_3590|M.ulcerans_Agy99           SSVALVAFVASSRS-HPTPLIDPAFLRVRSFVAGNLLTLVAAAGFYCYVL
MLBr_01562|M.leprae_Br4923          ALVAAIAFAVVERT-AENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTV
                                    .      *   .      *::   .:                       .

MSMEG_0827|M.smegmatis_MC2_155      MLIIWLQGIWLPLHGYSFESTPLWAGIYMLPMTIGFLVSGPLAGSLSDR-
Mvan_0726|M.vanbaalenii_PYR-1       MLIIWLQGIWLPLRGYDFEVTPLWAAIYMLPITVGFLLAGPIAGWLSDR-
MAV_2104|M.avium_104                MLIIWLQGIWLPLHGYRFESTPLWAGIYMLPTTIGFLIAAPVAGWLADR-
MAB_4195c|M.abscessus_ATCC_199      MLIIWLQGIWLPLRGYSYESTPLWAGIFLLPMTLGFLVAGPVAGLLSDR-
Mb1282|M.bovis_AF2122/97            PVTFYAQAVCG--------LSPTHTAVLFAPTAIVGGVLAPFVGMIIDRS
Rv1250|M.tuberculosis_H37Rv         PVTFYAQAVCG--------LSPTHTAVLFAPTAIVGGVLAPFVGMIIDRS
Mflv_0301|M.gilvum_PYR-GCK          LLVLQLQTVSG--------FSPVAAGTALLPFTIVMLLFSSRAGALSGRI
MMAR_3642|M.marinum_M               LTTQFLQNVRG--------YTPGATGLMILPFSAGVAVVSPLVGSLVARV
TH_2682|M.thermoresistible__bu      VSMQYMQLMLG--------YSALQTAFALTPLTIPLLLLSVTTQWYLPRL
MUL_3590|M.ulcerans_Agy99           THVLYLNYVWH--------YSLLKAGFAIAPAALIAAVVAAVLGRIADQR
MLBr_01562|M.leprae_Br4923          SIGLYIQDILG--------YSALRAGIGFIPFVIAMGIGLGVSSQLVSRF
                                          : :           :   :.  : *      :          : 

MSMEG_0827|M.smegmatis_MC2_155      FGARPFTVGGMVIMAATFVALVMIPVDFDYW-LFAVLVFLNGLGGGIFTA
Mvan_0726|M.vanbaalenii_PYR-1       YGARPLTVGGMLLMAGSFIALVMIPVDFDYW-VFAVLIFLNGVGGGIFTA
MAV_2104|M.avium_104                FGARPFAVAGMLLMAVTFIGLLMIPVNFDYR-VFALLIFLNALGGGLFAA
MAB_4195c|M.abscessus_ATCC_199      YGARPFATGGMVLSAVTFLALIAIPVNFNYW-VFALLIFLNGLGSAIFTA
Mb1282|M.bovis_AF2122/97            HPLCVLGFGFSVLAIAMTWLLCEMAPGTPIW-RLVLPFIALGVAGAFVWS
Rv1250|M.tuberculosis_H37Rv         HPLCVLGFGFSVLAIAMTWLLCEMAPGTPIW-RLVLPFIALGVAGAFVWS
Mflv_0301|M.gilvum_PYR-GCK          GPRLPMTVGPVLAGLGLLLMLRIGEDASWVF-DVAPAALVFGAGMVLVVA
MMAR_3642|M.marinum_M               GARVLILIGLGLLMLGLLTLIASEHRSWALV-LVGLG--FCGTGVALCLT
TH_2682|M.thermoresistible__bu      GLRAVISTGLLLIAAG-LFYARTLEIASPYL-DLAVPLLIMSTGIGLCTA
MUL_3590|M.ulcerans_Agy99           GHRLVVMAGAIIWAGSLVWYLQRVGTEPNFLREWLPGQLLQGIGVGATLP
MLBr_01562|M.leprae_Br4923          SPRVLTIGGGWLLMVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVV
                                            .  :                             . .      

MSMEG_0827|M.smegmatis_MC2_155      PNSAAVMSAVPAG-ERGAASGVRATFFNAGSSLSIGIFFSLM--------
Mvan_0726|M.vanbaalenii_PYR-1       PNTAAIMSSVPPS-ERGAASGVRATFFNAGSSLSIGIFFSLM--------
MAV_2104|M.avium_104                PNTAVIMSSVPPR-DRGAASGVRSTFFNAGSALSIGVFFSLM--------
MAB_4195c|M.abscessus_ATCC_199      PNTAAIMSSVPAH-QRGAASGVRGTFFNAGSSLSIGIFFSLM--------
Mb1282|M.bovis_AF2122/97            PLTVTATRNLRPH-LAGASSGVFNAVRQLGAVLGSASMAAFM--------
Rv1250|M.tuberculosis_H37Rv         PLTVTATRNLRPH-LAGASSGVFNAVRQLGAVLGSASMAAFM--------
Mflv_0301|M.gilvum_PYR-GCK          PLTATVLDAAPEH-MAGSASGVNNAVARAGGLLAVAVLPGVAG-------
MMAR_3642|M.marinum_M               PITTVAMTAVPPE-RAGMASGIMSAQRAIGSTIGFAVLGSVL--------
TH_2682|M.thermoresistible__bu      PSTSAIMGAVPDE-KHGVASAVNDTTREIGAALGIAVAGSVL--------
MUL_3590|M.ulcerans_Agy99           VLGSAALAGLTKGGSYATASAVVSTTRQLGAVIGVALLVILIGKPAPGTG
MLBr_01562|M.leprae_Br4923          PLTLSAIAGVGFD-RIGPVSAIALMLQSLGGPLVLAVIQAVIT-------
                                                    .  *.:       *. :  .    .         

MSMEG_0827|M.smegmatis_MC2_155      ---------------------IVGLAGTLPTAMSAGLEQQGVSASVAHEV
Mvan_0726|M.vanbaalenii_PYR-1       ---------------------VVGLANTLPGALSSGLQEQGVSADVAQQV
MAV_2104|M.avium_104                ---------------------VVGLAGTLPHALSSGLQQQGVPAAVAQDA
MAB_4195c|M.abscessus_ATCC_199      ---------------------IVGLSATMPAAMQSGLTVQGVPASTAAQV
Mb1282|M.bovis_AF2122/97            ---------------------TSRIAAEMPGGVDALTGPAGQDATVLQLP
Rv1250|M.tuberculosis_H37Rv         ---------------------TSRIAAEMPGGVDALTGPAGQDATVLQLP
Mflv_0301|M.gilvum_PYR-GCK          ---------------------ISGNDYADPAAFSAGFHTAVVISAVLMVA
MMAR_3642|M.marinum_M               ---------------------AAWLSATLEPHLEPAVPDPVQRHTIAEVI
TH_2682|M.thermoresistible__bu      ---------------------AAEYGDRLRPHLGALPEPVRQAASNSLAE
MUL_3590|M.ulcerans_Agy99           VEALRHGWVLAAVCFAAVAVLAGFLGRTQQGADVAGAPESGVARAPARPQ
MLBr_01562|M.leprae_Br4923          -------------------------SRTLYLGGTTGPVKFMNDAQLRALD
                                                                      .               

MSMEG_0827|M.smegmatis_MC2_155      ANLPP---------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       ADLPP---------------------------------------------
MAV_2104|M.avium_104                AALPP---------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      SSLPP---------------------------------------------
Mb1282|M.bovis_AF2122/97            EFVREPFAAAMSQSMLLPA-------------------------------
Rv1250|M.tuberculosis_H37Rv         EFVREPFAAAMSQSMLLPA-------------------------------
Mflv_0301|M.gilvum_PYR-GCK          AAVLA---------------------------------------------
MMAR_3642|M.marinum_M               IDSAN---------------------------------------------
TH_2682|M.thermoresistible__bu      ALEAAR--------------------------------------------
MUL_3590|M.ulcerans_Agy99           PVTPRPAAAPARPPQTTADGDLLRQLPLFAGLPAATMAELRHHTDEIELQ
MLBr_01562|M.leprae_Br4923          HGYTYG--------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_2104|M.avium_104                --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1282|M.bovis_AF2122/97            --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3642|M.marinum_M               --------------------------------------------------
TH_2682|M.thermoresistible__bu      --------------------------------------------------
MUL_3590|M.ulcerans_Agy99           AGSYLFHEVDPSDALYVVRSGRLRVVQRDLVLRELGRGEVVGELGLLIDA
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------------------------VGSLFAAFLGYNPIAELLAPFHAL
Mvan_0726|M.vanbaalenii_PYR-1       --------------------------VGSLFAAFLGYNPIAELLEPYHAL
MAV_2104|M.avium_104                --------------------------VGSLFAAFLGYNPIAELLAPSHAL
MAB_4195c|M.abscessus_ATCC_199      --------------------------VGSLFAAFLGYNPVGELLAPSGVL
Mb1282|M.bovis_AF2122/97            ------------------FVALFGIVAALFLVDFTGAAVAKEPLPESDGD
Rv1250|M.tuberculosis_H37Rv         ------------------FVALFGIVAALFLVDFTGAAVAKEPLPESDGD
Mflv_0301|M.gilvum_PYR-GCK          -----------------------------------AIGIRRAPARSDERM
MMAR_3642|M.marinum_M               -----------------------------PRAHVGGIVPRREIVHRDPVA
TH_2682|M.thermoresistible__bu      -------------------------QLGPQGARLAEFAQSAFLEAMHVSL
MUL_3590|M.ulcerans_Agy99           PRSASVQAMRDFVLIRLSKAQFNRIADRGVLAALVGTLATRLHTAPPPTV
MLBr_01562|M.leprae_Br4923          ----------------------------------LLWVAGAVVIVGVAAL
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      QQPGVNADVLTGQQFFPQLITAPFHAGVTVVFIAAAVMMVIGAIASMFN-
Mvan_0726|M.vanbaalenii_PYR-1       QQPGVNAEVLTGQTFFPHLIIEPFHSGLVVVFVAAAIMMVIGMIASMFN-
MAV_2104|M.avium_104                QQPGVNAATLTGKSFFPELISGPFHAGLVVVFVAAALMMVTGALASLVN-
MAB_4195c|M.abscessus_ATCC_199      EQPGVNTAELTGQSFFPNLITEPFHAGLVVVFGAAALMMAVAALASLGA-
Mb1282|M.bovis_AF2122/97            ADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTS
Rv1250|M.tuberculosis_H37Rv         ADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTS
Mflv_0301|M.gilvum_PYR-GCK          AVENCTHCAITGLPAHPAAETR----------------------------
MMAR_3642|M.marinum_M               IAEEDFIEGIRVAFFIATASLGFVFLAGWRWFPRGGAGMLG---------
TH_2682|M.thermoresistible__bu      IVLGALCALAAAFVAVWAPGRDGRQYGFVERWTSRWSGEEAGGAVAEHDD
MUL_3590|M.ulcerans_Agy99           DRPASPEAVIAVIGLGAAVPVRPVALALLNALSARVTAVDPGRVDRAGLE
MLBr_01562|M.leprae_Br4923          FIGYTPEQVAYAQEVKEAVDAGEL--------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------AGRYGTEAGADNEA----------------------------
Mvan_0726|M.vanbaalenii_PYR-1       --------PGRYAEVVETP-------------------------------
MAV_2104|M.avium_104                --------PGRYADDVEEI-------------------------------
MAB_4195c|M.abscessus_ATCC_199      --------GGKYAHADD---------------------------------
Mb1282|M.bovis_AF2122/97            AQGMPPGPPGRRAWQADTESTAPSAL------------------------
Rv1250|M.tuberculosis_H37Rv         AQGMPPGPPGRRAWQADTESTAPSAL------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3642|M.marinum_M               -------DAEREADAVGL--------------------------------
TH_2682|M.thermoresistible__bu      GGVRAATGDGWEHGTVDDP-------------------------------
MUL_3590|M.ulcerans_Agy99           RAEASADKVVLDASANDTGWRDFCLRAADRIVLVSEGPAPRDTQLPARAV
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_2104|M.avium_104                --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1282|M.bovis_AF2122/97            --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3642|M.marinum_M               --------------------------------------------------
TH_2682|M.thermoresistible__bu      --------------------------------------------------
MUL_3590|M.ulcerans_Agy99           GADLVLIGAPASQEDRSRWEELIPPRSVHSVSYRSLKDDVRPLAARITGG
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_2104|M.avium_104                --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1282|M.bovis_AF2122/97            --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3642|M.marinum_M               --------------------------------------------------
TH_2682|M.thermoresistible__bu      --------------------------------------------------
MUL_3590|M.ulcerans_Agy99           SIGLVLGGGGARAFAHLGVLDELEAAGIVVDRFAGTSMGAVIAALAASGL
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_2104|M.avium_104                --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1282|M.bovis_AF2122/97            --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3642|M.marinum_M               --------------------------------------------------
TH_2682|M.thermoresistible__bu      --------------------------------------------------
MUL_3590|M.ulcerans_Agy99           DAAGVDAHVFEYLVRHNPLGDYTLPSKGLVRGRRTMGLLREAYSGRMVEE
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_2104|M.avium_104                --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1282|M.bovis_AF2122/97            --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3642|M.marinum_M               --------------------------------------------------
TH_2682|M.thermoresistible__bu      --------------------------------------------------
MUL_3590|M.ulcerans_Agy99           LPKEFRCVSVDLLARQAVVHRRGPVAEVVGCSLRVPGLYPPQIYNGQLHV
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_2104|M.avium_104                --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1282|M.bovis_AF2122/97            --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3642|M.marinum_M               --------------------------------------------------
TH_2682|M.thermoresistible__bu      --------------------------------------------------
MUL_3590|M.ulcerans_Agy99           DGGVLNNLPVTALTRAEGPMIAVSVGFGGNPSGGQPRRSGPIQVPGIGDT
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_2104|M.avium_104                --------------------------------------------------
MAB_4195c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1282|M.bovis_AF2122/97            --------------------------------------------------
Rv1250|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3642|M.marinum_M               --------------------------------------------------
TH_2682|M.thermoresistible__bu      --------------------------------------------------
MUL_3590|M.ulcerans_Agy99           LMRTMMMGSRTVADAAQAEALVVIRPDTRAVGLLEFHQIDAAREAGRAAA
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0827|M.smegmatis_MC2_155      ---------------------------------------
Mvan_0726|M.vanbaalenii_PYR-1       ---------------------------------------
MAV_2104|M.avium_104                ---------------------------------------
MAB_4195c|M.abscessus_ATCC_199      ---------------------------------------
Mb1282|M.bovis_AF2122/97            ---------------------------------------
Rv1250|M.tuberculosis_H37Rv         ---------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          ---------------------------------------
MMAR_3642|M.marinum_M               ---------------------------------------
TH_2682|M.thermoresistible__bu      ---------------------------------------
MUL_3590|M.ulcerans_Agy99           RAALPQIIPLLRSGPAGQTTGRAIDRSARALRTDARRPA
MLBr_01562|M.leprae_Br4923          ---------------------------------------