For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2682 | - | - | 100% (559) | transmembrane efflux protein |
| M. thermoresistible (build 8) | TH_3412 | - | 2e-44 | 27.51% (498) | PUTATIVE putative major facilitator superfamily MFS_1 |
| M. thermoresistible (build 8) | TH_3965 | - | 2e-43 | 26.42% (511) | PUTATIVE drug transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2361c | - | 3e-65 | 33.40% (539) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_5055 | - | 0.0 | 64.42% (520) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2333c | - | 1e-63 | 33.87% (499) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_01562 | - | 5e-39 | 28.01% (432) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_0945 | - | 2e-56 | 31.58% (418) | EmrB/QacA family drug resistance transporter |
| M. marinum M | MMAR_5192 | - | 1e-100 | 41.72% (513) | integral membrane transport protein |
| M. avium 104 | MAV_2104 | - | 1e-46 | 29.85% (536) | major facilitator superfamily protein MFS_1 |
| M. smegmatis MC2 155 | MSMEG_1427 | - | 0.0 | 65.84% (524) | transmembrane efflux protein |
| M. ulcerans Agy99 | MUL_0911 | - | 1e-93 | 40.36% (498) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_0664 | - | 1e-58 | 33.73% (501) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2361c|M.bovis_AF2122/97 --------------------------------------------------
Rv2333c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997 ------------------------------------------MEAAVGAL
TH_2682|M.thermoresistible__bu -------------------------------MVDALSQPGQDIGASVAAL
MSMEG_1427|M.smegmatis_MC2_155 -------------------------------MTDALVEPGQNIDSRMAEL
Mflv_5055|M.gilvum_PYR-GCK -------------------------------MVDTLPRSDQDIDAAVMTL
MMAR_5192|M.marinum_M -------------------------------MLTTLPTPPQTP----LVR
MUL_0911|M.ulcerans_Agy99 ----------------------------------MRIQP----------V
Mvan_0664|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2104|M.avium_104 --------------------------------------------------
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mb2361c|M.bovis_AF2122/97 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVAS
Rv2333c|M.tuberculosis_H37Rv MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVAS
MAB_0945|M.abscessus_ATCC_1997 SERRKIVILGSCCLSLLIVSMDSTIVNVALPTIRADFGATTSQLQWVIDI
TH_2682|M.thermoresistible__bu STRARVWLLTVACMGVALVISSMVALNAALPDIAVETAATQSQLTWVVDG
MSMEG_1427|M.smegmatis_MC2_155 SVRQRYWLLIVACLDVSLVISSMVALNAALPDIATQTSATQAQLTWVIDG
Mflv_5055|M.gilvum_PYR-GCK SKRRRIWLLAVASIDVLMVISSMVALNAALPDIALQTSATQTQLTWIVDG
MMAR_5192|M.marinum_M RPGHQGLVLAVTCLALGTVVAAMASLNVALPDIARQTHADQTQQAWIVDA
MUL_0911|M.ulcerans_Agy99 FRDHPILALAVICLSVFVISVDATIVNVALPTLSRELGADTAQLQWIVDA
Mvan_0664|M.vanbaalenii_PYR-1 -MTRRWSALAVLTLAVLLIGIDGTVLALATPFISADLGATGTQILWIGDI
MAV_2104|M.avium_104 ------MLLAMINSSIVLISLPAIFRGIGLNPLAP---ANIGYLLWMLMG
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
: . : *
Mb2361c|M.bovis_AF2122/97 YSLGMAVFIMSAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAV---
Rv2333c|M.tuberculosis_H37Rv YSLGMAVFIMSAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAV---
MAB_0945|M.abscessus_ATCC_1997 YTLGLASLLMLSGAAGDRLGRRKVFHLGLSIFAIGSLLCSVAPTVGL---
TH_2682|M.thermoresistible__bu YTLVLACLLLPAGAIGDRYGRRGAMLVGLGLFTVASAAPLVLDGPLT---
MSMEG_1427|M.smegmatis_MC2_155 YTLVLACLLLPAGAVGDRYGRRGALLIGLAIFSLASAAPLIFDSPVQ---
Mflv_5055|M.gilvum_PYR-GCK YTLALACLLLPAGALGDRYGRRGALLVGLAIFALASLAPVFLDSPTQ---
MMAR_5192|M.marinum_M YSLVFASLLLPAGAVGDRYGRRLALLVGLVVFGAGSGVATLTTDPTA---
MUL_0911|M.ulcerans_Agy99 YTLVMSGLLLSAGSLSDRYGRRGWLSAGLILFALTSALAAQVNSADT---
Mvan_0664|M.vanbaalenii_PYR-1 YSFVLAALLISMGSLGDRIGHRKLLLCGATAFAVISAVTAYSTSPQM---
MAV_2104|M.avium_104 YLVVTAVLVVFVGRLGDMFGRVRIYNAGFAVFTVAAIALSFDPFPLTGGA
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVT---
* . . ::: . .* *: * * :
Mb2361c|M.bovis_AF2122/97 --LTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIGIWTAIASIGT
Rv2333c|M.tuberculosis_H37Rv --LTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIGIWTAIASIGT
MAB_0945|M.abscessus_ATCC_1997 --LIAARLLQAVGGSMLNPVALSIISQVFTGRVERARALGFWGAVVGISM
TH_2682|M.thermoresistible__bu --LILSRMVAGVGAAFVMPATLSLLTAAYPRAQ-RNKAVGIWAAVAGSGA
MSMEG_1427|M.smegmatis_MC2_155 --LIVARAVAGAGAAFIMPATLSLLTAAFPKSE-RNKAVGVWAGVVGSGA
Mflv_5055|M.gilvum_PYR-GCK --IIVARAVAGVGAALIMPATLSLLTSAFPKSE-RNKAVGIWAGVAGSGA
MMAR_5192|M.marinum_M --LAGLRALLGVGAALIMPATLSTITSSFPAQR-RAAAVSIWTAVAGASG
MUL_0911|M.ulcerans_Agy99 --LVAARAAMGVGAAVIFPTTLGLITNIFTDPVPRAKAIGLWTAMVGVGV
Mvan_0664|M.vanbaalenii_PYR-1 --LILTRALLGMAGATLTPATLALIRGLFPDQRERSIAVGIWASAFSAGA
MAV_2104|M.avium_104 VWLIGWRVVQGVGGAILMALSAAILTDAFPSNQ-RGMALGFNMVAAVAGS
MLBr_01562|M.leprae_Br4923 --LVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGS
: * . ..: . : :. : * .. .
Mb2361c|M.bovis_AF2122/97 TTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARRFD
Rv2333c|M.tuberculosis_H37Rv TTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARRFD
MAB_0945|M.abscessus_ATCC_1997 ALGPIVGGLLIQWVGWRAVFWINLPVCVLAFVLTAVFVPETKSATMRDID
TH_2682|M.thermoresistible__bu VVGFLGTGVLLHFWSWPSIFWA-FTVSGAGLFVLACTVASSRDHRATPLD
MSMEG_1427|M.smegmatis_MC2_155 IVGFLVTGGLLHFWTWQSIFVT-FTIASVGLFIVTCTVPSSRDDSAAPLD
Mflv_5055|M.gilvum_PYR-GCK VFGFLGTGVLLHFFSWQSIFYM-FAAGALLMFIATCTIGSSRDETATPID
MMAR_5192|M.marinum_M VVGLLASGLLLQWWSWQSIFWLNVLLAAVALTGTLLFVPESAERDPAPLD
MUL_0911|M.ulcerans_Agy99 AVGPITGGWLLEHFSWGSIFLVNVPIAVAAMAGAILFVPTSRDPAAPRVD
Mvan_0664|M.vanbaalenii_PYR-1 ALGPVVGGVLLEHFWWGSVFLINIPVMVILLVGGVLLLPEHRNPDPGPWD
MAV_2104|M.avium_104 FLGLLFGG-LLSEWDWRAIFWVGVPVGVLGTVWGMRSLHELGVRTPGPLD
MLBr_01562|M.leprae_Br4923 VMGLVVGG-ALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKER-MKLD
* * : * * . : *
Mb2361c|M.bovis_AF2122/97 LSGQLLFIVAVGALVYAVIEGPQ------IGWTSVQTIVMLWTAAVGCAL
Rv2333c|M.tuberculosis_H37Rv LSGQLLFIVAVGALVYAVIEGPQ------IGWTSVQTIVMLWTAAVGCAL
MAB_0945|M.abscessus_ATCC_1997 PVGQALAVLFLFGIVFALIEGPS------LGWATPGLIVVLAVALAAFAV
TH_2682|M.thermoresistible__bu WPGAVLIGGAVAVFVYGVLEAPV------HGWTHPVVYGSMAAGVALALA
MSMEG_1427|M.smegmatis_MC2_155 WLGAALIGTAVAAFVFGVVEAPV------RGWTHPSVWGAMAGGVALAAA
Mflv_5055|M.gilvum_PYR-GCK WVGGALIGTAIAVFVLGVVEAPA------RGWTDPVVLGCLAAGVVLAVA
MMAR_5192|M.marinum_M VVGAVLAAAGIAVLVYAVIEAPA------YGWTDPVTVGGIAVGLLILAG
MUL_0911|M.ulcerans_Agy99 VPGLMLSAVGITALVYTIIEAPN------WGWTSTRASGGFIAAAIVLVG
Mvan_0664|M.vanbaalenii_PYR-1 LPSVALSMVGMLAVVYAVKEGFAGL----AHGVGPDVAVAGLVGAAALTM
MAV_2104|M.avium_104 WPGTVTFGVGLTVVLVGITYGIQPYGGHPTGWTNPWVLGSIAFGLLLLIV
MLBr_01562|M.leprae_Br4923 AAGAILATLACTAAVFAFSMGPE------KGWISLTTIGSGLVALVAAIA
. : . . .
Mb2361c|M.bovis_AF2122/97 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQ-
Rv2333c|M.tuberculosis_H37Rv FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQ-
MAB_0945|M.abscessus_ATCC_1997 FLRYESRRRHPFIDLRFFRSIPFASATLTAICACMAWSAFLFTMSLYLQ-
TH_2682|M.thermoresistible__bu FAVVELRSAHPLLDIRLFAKPDFTTGAVGVTFFFLANFGFFFVSMQYMQ-
MSMEG_1427|M.smegmatis_MC2_155 FTAVQLRRTHPLLDVRLFRDPNFATGSAGVTFLFFATFGFFFVSMQYIQ-
Mflv_5055|M.gilvum_PYR-GCK FAMVQLRREHPLLDVRLFTRPDFATGAVGITFLFMANFGFFFIEMQFMQ-
MMAR_5192|M.marinum_M FVVIEMGRRYPLLDPRLFTNRRFAAGSLSITLQFFALFGFLFVIMQYLQ-
MUL_0911|M.ulcerans_Agy99 FALWERRSSHPMLDVSVFANRRFSGGSLAVTAGFLTLFGFIFVITQYFQ-
Mvan_0664|M.vanbaalenii_PYR-1 FVRRQLRLPAPLIDVRLFANPRFSGVVAANLLSVLGLSGLVFFLSQYFQ-
MAV_2104|M.avium_104 FCFIELRAPQPMVNVRLFRSAGFGMGNLANLMSSSGRGGLQFMLIIWLQG
MLBr_01562|M.leprae_Br4923 FAVVERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQ-
* : *.: .* .: . ::*
Mb2361c|M.bovis_AF2122/97 ---NVRGY----TPSVTGLMILPFSAAVAIVSPLVGHLVGRIGARVPILA
Rv2333c|M.tuberculosis_H37Rv ---NVRGY----TPSVTGLMILPFSAAVAIVSPLVGHLVGRIGARVPILA
MAB_0945|M.abscessus_ATCC_1997 ---GQRHF----SAMHTGLIYLPIAVGALVFSPISGRMVGRFGARPSLLA
TH_2682|M.thermoresistible__bu ---LMLGY----SALQTAFALTPLTIPLLLLSVTTQWYLPRLGLRAVIST
MSMEG_1427|M.smegmatis_MC2_155 ---LIMGY----SPIATAIALCPLVVPILAFGATTHLYLPLLGLRLTAFL
Mflv_5055|M.gilvum_PYR-GCK ---LVMGY----SALETAFALAPLAFPVLVLGGTLHLYLPKVGLRFAVTG
MMAR_5192|M.marinum_M ---SVRHY----SALTAALGLLAMPIGMIPSSRLSPYLTERFGIRLPWVA
MUL_0911|M.ulcerans_Agy99 ---FIKDY----TALQTGVRLLPVAFSIALAAILGPRLVERVGTTAVVAA
Mvan_0664|M.vanbaalenii_PYR-1 ---LVHGY----GPLKAGLAELPAAVTATVFGVLAGVAVRYVSHRAVLAT
MAV_2104|M.avium_104 IWLPLHGYRFESTPLWAGIYMLPTTIGFLIAAPVAGWLADRFGARPFAVA
MLBr_01562|M.leprae_Br4923 ---DILGY----SALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIG
: . :.. . ..
Mb2361c|M.bovis_AF2122/97 G-LCMLMLGLLMLI----FSEHRSSALVLVGLGLCGSGVALCLTPITTVA
Rv2333c|M.tuberculosis_H37Rv G-LCMLMLGLLMLI----FSEHRSSALVLVGLGLCGSGVALCLTPITTVA
MAB_0945|M.abscessus_ATCC_1997 AGTLFLTASLLLTR----VSEATPIWELLVTFAIFGAGFAMVNAPITNAA
TH_2682|M.thermoresistible__bu GLLLIAAGLFYART----LEIASPYLDLAVPLLIMSTGIGLCTAPSTSAI
MSMEG_1427|M.smegmatis_MC2_155 GLLVTAVGLWCMCT----LETGSTYFDFAWPLFIMSIGVGLSTAPVTSAI
Mflv_5055|M.gilvum_PYR-GCK GLLLLAGGLFLMRF----LDADATFLDIMWPLLLAASGIGLCTAPTTSAI
MMAR_5192|M.marinum_M GLLIVAEGLMVLAH----LDSADPYWHIASGLIPLGAGLGLAMPPATTAI
MUL_0911|M.ulcerans_Agy99 GLAVFAAALAWAST----ADATTPYTQITLQMLLLGGGLGLTTAPATEAI
Mvan_0664|M.vanbaalenii_PYR-1 GLALVGVAMAAMTTSLLVFTPVAPYLPLGVALFVVGVGLGLAFTVASDVI
MAV_2104|M.avium_104 GMLLMAVTFIGLLM----IPVNFDYRVFALLIFLNALGGGLFAAPNTAVI
MLBr_01562|M.leprae_Br4923 GGWLLMVAMLYGWAFMN--RGVPYFPNLLAPIVVGGIGIGMAVVPLTLSA
. . : . * .: :
Mb2361c|M.bovis_AF2122/97 MTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLEPHLERA
Rv2333c|M.tuberculosis_H37Rv MTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLEPHLERA
MAB_0945|M.abscessus_ATCC_1997 VSGMPLDRAGAASAVTSTSRQVGVSIGVALCGSIGTPALWFMCAG-----
TH_2682|M.thermoresistible__bu MGAVPDEKHGVASAVNDTTREIGAALGIAVAGSVLAAEYGDRLRPH----
MSMEG_1427|M.smegmatis_MC2_155 MGAAPDEKQGVASAVNDTTREIGAALGIAVAGSVLAAQYERHLSPA----
Mflv_5055|M.gilvum_PYR-GCK MNAAPDEKQGVASAVNDATREIGAALGIAVAGSILAAVYHRSLASR----
MMAR_5192|M.marinum_M TGALPSRLQNVGSAVNDLARELGGALGIAVLGSLLTATYRNHLPTAGAVS
MUL_0911|M.ulcerans_Agy99 MGSLPADRAGVGSAVNDTTRELGGTLGVAIAGSVFASVYSGQLGSAS---
Mvan_0664|M.vanbaalenii_PYR-1 LASVPRERAGAAAAVSETAYELGMALGIAMLGSIVTAVYRTVVIAP----
MAV_2104|M.avium_104 MSSVPPRDRGAASGVRSTFFNAGSALSIGVFFSLMVVGLAGTLPHALSSG
MLBr_01562|M.leprae_Br4923 IAGVGFDRIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTT----
. . :.: * .: ..: :: .
Mb2361c|M.bovis_AF2122/97 VPDPVQRHVLAEIIIDSANPRAHVGGIVPR------RHIEHRDP------
Rv2333c|M.tuberculosis_H37Rv VPDPVQRHVLAEIIIDSANPRAHVGGIVPR------RHIEHRDP------
MAB_0945|M.abscessus_ATCC_1997 -----------------------LGLLIAT------LGIVSTSP------
TH_2682|M.thermoresistible__bu --LGALPEPVRQAASNSLAEALEAARQLG--------PQGARLA------
MSMEG_1427|M.smegmatis_MC2_155 --LGAMPEAVRGPALNSLAEALTAAEHMG--------PQGAELA------
Mflv_5055|M.gilvum_PYR-GCK --LADFPEQIRTTATDSLAHALSISEQMG--------PQGARLS------
MMAR_5192|M.marinum_M AFCTGLHVSLTGAALTIVATAIAVAALLRRP----HRPGRHRRSRSAWRG
MUL_0911|M.ulcerans_Agy99 -ALATLPSDVRSAMKGSMAVAHKVIDQLP-------AGPAAGVR------
Mvan_0664|M.vanbaalenii_PYR-1 ----EIPSAAADLARDSLPGAIHAAHSLP-------ADQQSTLL------
MAV_2104|M.avium_104 LQQQGVPAAVAQDAAALPPVGSLFAAFLGYNPIAELLAPSHALQQPGVNA
MLBr_01562|M.leprae_Br4923 -------------------------------------GPVKFMN------
Mb2361c|M.bovis_AF2122/97 VAIAEEDFIEGIRVALLVAT------------------------------
Rv2333c|M.tuberculosis_H37Rv VAIAEEDFIEGIRVALLVAT------------------------------
MAB_0945|M.abscessus_ATCC_1997 AAVR-----SAQRLAPLIEG------------------------------
TH_2682|M.thermoresistible__bu -EFAQSAFLEAMHVSLIVLG------------------------------
MSMEG_1427|M.smegmatis_MC2_155 -QTARQAFVDATGSAVIILG------------------------------
Mflv_5055|M.gilvum_PYR-GCK -ELAQDAFIHAADRALLVLS------------------------------
MMAR_5192|M.marinum_M QQRARAGFTAASDPKRVELFQQRHRDPAGGSQDPARLAHRERLGQCREDL
MUL_0911|M.ulcerans_Agy99 -DAVNHAFLDGLQVATLVCAG-----------------------------
Mvan_0664|M.vanbaalenii_PYR-1 -DAARASFTHGLASASAAGAV-----------------------------
MAV_2104|M.avium_104 ATLTGKSFFPELISGPFHAG------------------------------
MLBr_01562|M.leprae_Br4923 -DAQLRALDHGYTYGLLWVAG-----------------------------
Mb2361c|M.bovis_AF2122/97 --ATLAVVFLAGWRWFPR-------------DVQTAGSDAKR--EAAYSD
Rv2333c|M.tuberculosis_H37Rv --ATLAVVFLAGWRWFPR-------------DVHTAGSDLSERLPTAMTV
MAB_0945|M.abscessus_ATCC_1997 --TTAREMSRVG--------------------------------------
TH_2682|M.thermoresistible__bu --ALCALAAAFVAVWAPG------------RDGRQYGFVERWT--SRWSG
MSMEG_1427|M.smegmatis_MC2_155 --SVVAVAAVLTGIWGPG------------RDGQQLRVIRRLR--SR---
Mflv_5055|M.gilvum_PYR-GCK --LLLLVAAVFVAIWSPG------------RDGRQWSVVRRLR--KN---
MMAR_5192|M.marinum_M GRPLERVRTEHDRVGDPGQPAGAYRRGQLTRTEPQLTQFVGFRGAKRFGG
MUL_0911|M.ulcerans_Agy99 ---IALAAAIVVGWLLPA------------RAGQPTPAQTEPALAQV---
Mvan_0664|M.vanbaalenii_PYR-1 --LLLTAAVAVWWLLRPG-----------SPGAAEVGVLADPGVHRDPGR
MAV_2104|M.avium_104 ---LVVVFVAAALMMVTG----------------ALASLVNPGRYADDVE
MLBr_01562|M.leprae_Br4923 --AVVIVGVAALFIGYTP---------------EQVAYAQEVKEAVDAGE
Mb2361c|M.bovis_AF2122/97 DRRVRG--------------------------------------
Rv2333c|M.tuberculosis_H37Rv ECAVSHMPGATWCRLWPA--------------------------
MAB_0945|M.abscessus_ATCC_1997 --------------------------------------------
TH_2682|M.thermoresistible__bu EEAGGAVAEHDDGGVRAATGDGWEHGTVDDP-------------
MSMEG_1427|M.smegmatis_MC2_155 --------------------------------------------
Mflv_5055|M.gilvum_PYR-GCK --------------------------------------------
MMAR_5192|M.marinum_M QPSFEGAHRRVDPRWQARAGRSHQPVGHVQPGSHQQRGNQLGGG
MUL_0911|M.ulcerans_Agy99 --------------------------------------------
Mvan_0664|M.vanbaalenii_PYR-1 DARVDAPGGAELGDRNS---------------------------
MAV_2104|M.avium_104 EI------------------------------------------
MLBr_01562|M.leprae_Br4923 L-------------------------------------------