For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRTHGWSGSAPATDEEAIARILAAAGKAIDERGADFSIADVARTLGVTRQTVYRYFPSTDALLVAAAVHA ASGFLDRLAAHLSGITDPVEAVTEAIATALEWVPQDKHLGLLISPGRADAHTESVTSDVAVDFARAMLRK FDVDWAGLGFGDDDLDELAEHLLRIIQSFIIDPGRPPRTGATLRSYLRRWVGAAVKPAQASVQSPRV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5854 | - | - | 100% (207) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2106 | - | 4e-51 | 49.02% (204) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 3e-08 | 39.51% (81) | TetR-type regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 2e-05 | 41.82% (55) | transcriptional regulatory repressor protein (TETR-family) |
| M. gilvum PYR-GCK | Mflv_1606 | - | 3e-80 | 71.28% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-09 | 28.21% (195) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01070 | - | 5e-05 | 36.21% (58) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4765 | - | 1e-48 | 50.00% (194) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 4e-47 | 47.69% (195) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_1115 | - | 3e-64 | 59.69% (196) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1262 | - | 5e-90 | 78.39% (199) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 4e-40 | 47.65% (170) | hypothetical protein MUL_4888 |
| M. vanbaalenii PYR-1 | Mvan_5152 | - | 3e-82 | 72.31% (195) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5854|M.smegmatis_MC2_155 -------------MRTHGWSGSAPATDEEAIARILAAAGKAIDE-RGADF
TH_1262|M.thermoresistible__bu -------------MRTHGWGGSAPASDEEAIARILEAAKRTIEE-RGAEF
Mflv_1606|M.gilvum_PYR-GCK -------MAYSAFVRTHGWSGAKPASDDEAVARILEAAGKAIEE-RGADF
Mvan_5152|M.vanbaalenii_PYR-1 ----MTGLAYSSLVRTHGWSGAKPASDEEAVARILAAAGKVIEE-RGADF
MAV_1115|M.avium_104 -------------MRRHGWSGDIPADDEEAVARILTATRRAIDE-RGT-V
MMAR_0226|M.marinum_M ------------MARRRGWNGAPPASDEEASRRIVDTAVRLIAE-TGSDV
MUL_4888|M.ulcerans_Agy99 ------------MVSRPKRRGVSRIG------RGVRRHRRGIAE-TGSDV
MAB_4765|M.abscessus_ATCC_1997 ------------MARRRGWDGQPPSSDEEAAERIVAAAVKLIGE-TGSAV
Mb3885|M.bovis_AF2122/97 -MTTSAASQASLP---RGRRTARPSGDDRELAILATAENLLEDR-PLADI
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAER-PLGDF
Rv1255c|M.tuberculosis_H37Rv ---------------MAGTDWLSARRTELAADRILDAAERLFTQRDPASI
. .
MSMEG_5854|M.smegmatis_MC2_155 SIADVARTLGVTRQTVYRYFPSTDALLVAAAVHAASGFLDRLAAHLSGIT
TH_1262|M.thermoresistible__bu SIADVARAVGVTRQTVYRYFPSTDALLVAAAMHAAGDFLDRLAVHLQGIT
Mflv_1606|M.gilvum_PYR-GCK SISDVARTVGVTRQTVYRYFSSTEALLVAAAVHAVDGFLDRLAAHLVGVT
Mvan_5152|M.vanbaalenii_PYR-1 SISDVARTVGVTRQTVYRYFPSTEALLVAAAVHAVDGFLERLTAHMAGIT
MAV_1115|M.avium_104 SVSQVASTLGVTRQTIYRYFPTHEALLGATALSAVEGFLDRLAAHLGSIT
MMAR_0226|M.marinum_M SLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLTEAVRGMR
MUL_4888|M.ulcerans_Agy99 SLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLTEAVRGMR
MAB_4765|M.abscessus_ATCC_1997 SLADVAAELGVIRQTVYRYFPTADALMHAASLASVDGFLDRLTHVVRGIT
Mb3885|M.bovis_AF2122/97 SVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPA
MLBr_01070|M.leprae_Br4923 SVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLP
Rv1255c|M.tuberculosis_H37Rv GMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVV
.: ::* * * *.* *: : :*: : :
MSMEG_5854|M.smegmatis_MC2_155 --DPVEAVTEAIATALEWVPQDKHLGLLISPGRA-DAHTESVTSDVAVDF
TH_1262|M.thermoresistible__bu --DPVEAVAEAIATTLEWLPEDTHIGLLVAPGRP-TAHTESVTSDVAIDF
Mflv_1606|M.gilvum_PYR-GCK --DPPEAVTEAVATALEWLPREKYIGLIMAPGG--STHVQSVTSDIALRF
Mvan_5152|M.vanbaalenii_PYR-1 --DPAEAVTEAVATALEWLPREKYIGLIMVPGR--STHVQSVTSDIALRF
MAV_1115|M.avium_104 --DPTEAVVEGIAYTFEQLAHDRYLSLVFQPGKA-SAFTAGVTSDIAISF
MMAR_0226|M.marinum_M --DPAEAMAEAVMFTLRDVVRTPHLGILIAQPYA-HTHPENLTSEEAQVF
MUL_4888|M.ulcerans_Agy99 --DPAEAMAEAVMFTLRDVVRTPHLGILIAQPYA-HTHPENLTSEEAQVF
MAB_4765|M.abscessus_ATCC_1997 --DPAEALTEGVLYTLEEVTRTPHLGIMMSEPYA-HSHTSDMTSDEAQAF
Mb3885|M.bovis_AF2122/97 DTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKW
MLBr_01070|M.leprae_Br4923 -ADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQW
Rv1255c|M.tuberculosis_H37Rv --EPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAAL
: .: :. : *
MSMEG_5854|M.smegmatis_MC2_155 ARAMLRKFDVDWAGLGF-GDDDLDELAEHL----LRIIQSFIIDPGR-PP
TH_1262|M.thermoresistible__bu ANRMLRRFDVDWAAVGY-SDADLDELAEHL----LRVIQSFVIDPGR-PP
Mflv_1606|M.gilvum_PYR-GCK ARDMVGRLDVDWTAAGF-DEAELDQLSEHL----LRIIQSFVLDPGR-PP
Mvan_5152|M.vanbaalenii_PYR-1 GRDMVGRLDVDWAAAGF-DDADLDQLSEHL----LRIIQSFVVDPGR-PP
MAV_1115|M.avium_104 GRSILQRFEVDWGAAGF-ADAGLDELVEVM----LRTLQSLIVDPGR-PP
MMAR_0226|M.marinum_M GVRMLERFDVDWAEYGFADESARHDLVEFL----LRVLLSFFVAPNV-PS
MUL_4888|M.ulcerans_Agy99 GVRMLERFDVDWAEYGFADESARHDLVEFL----LRVLLSFFVAPNV-PS
MAB_4765|M.abscessus_ATCC_1997 GLRMLDRFDVDWVQYGY-DDAAKRELVEFA----LRIMLSFFVSPNE-AT
Mb3885|M.bovis_AF2122/97 IAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQP-SV
MLBr_01070|M.leprae_Br4923 IDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKP-LI
Rv1255c|M.tuberculosis_H37Rv AAAFLNSLGPD-------DPTTVERRARWV----VRMLTSLLMFPGRDEA
: : * : : .
MSMEG_5854|M.smegmatis_MC2_155 RTGATLRSYLRRWVGAAVKPAQASVQSPRV
TH_1262|M.thermoresistible__bu RDGQSLRAYLRRWVGAAVTGAR--------
Mflv_1606|M.gilvum_PYR-GCK RRGDELRSYLRRWVGNALLRR---------
Mvan_5152|M.vanbaalenii_PYR-1 RHGEQLRTYLRRWVGNALPLR---------
MAV_1115|M.avium_104 RTGAELRRFLQDWVAPAVRAHAISR-----
MMAR_0226|M.marinum_M RSDDELKSFIKRWVGGAILAQKR-------
MUL_4888|M.ulcerans_Agy99 RSDDELKSFIRRWVGGAIVAQKR-------
MAB_4765|M.abscessus_ATCC_1997 RSRDELRGFLKRWLGGAVLAQGR-------
Mb3885|M.bovis_AF2122/97 PEARVLDTLVHIWVTSIYGENR--------
MLBr_01070|M.leprae_Br4923 PDKKVIDTLVHIWLASIYGS----------
Rv1255c|M.tuberculosis_H37Rv DERAMIAEFVVPIVTPASAAARKAGHPGPE
: : :