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RTNARTRDPERKSRIMAAAADLVARKGFHAVSIAEIGAAAGITGSGIYRHFESKSAVLVALFDRVIDELL RDEQEILNTTDDLGQALDLLIAGQVEFVVADRELAQVYYNEINNLPEEDSRRLRRKQRLYLEEWVHLVNE SRVDLTDAEARTVVHAVIGAIQSPLFHNTGLPEDRLRALLTDAARAVLGLDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0360 | - | - | 100% (193) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4092 | - | 3e-26 | 37.80% (164) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0719 | - | 2e-20 | 33.33% (156) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 3e-26 | 36.81% (163) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4599 | - | 2e-48 | 52.20% (182) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 3e-26 | 36.81% (163) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 7e-11 | 25.00% (160) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2061c | - | 5e-24 | 36.52% (178) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3853 | - | 5e-25 | 35.06% (154) | putative regulatory protein |
| M. avium 104 | MAV_1669 | - | 1e-24 | 35.06% (154) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0343 | - | 7e-79 | 74.60% (189) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2795 | - | 3e-16 | 29.93% (147) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3785 | - | 3e-25 | 35.06% (154) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0360|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0343|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4599|M.gilvum_PYR-GCK --------------------------------------------------
Mb2534|M.bovis_AF2122/97 --------------------------------------------------
Rv2506|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1669|M.avium_104 --------------------------------------------------
MMAR_3853|M.marinum_M --------------------------------------------------
MUL_3785|M.ulcerans_Agy99 --------------------------------------------------
MAB_2061c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2795|M.thermoresistible__bu MSAAGSDAHRNGRHRPKNRKALIARASADAFGAQGYHAVSMEEIAARVGI
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
Mvan_0360|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0343|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4599|M.gilvum_PYR-GCK --------------------------------------------------
Mb2534|M.bovis_AF2122/97 --------------------------------------------------
Rv2506|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1669|M.avium_104 --------------------------------------------------
MMAR_3853|M.marinum_M --------------------------------------------------
MUL_3785|M.ulcerans_Agy99 --------------------------------------------------
MAB_2061c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2795|M.thermoresistible__bu SPAALYRHSQGKYDLFRDSVLGLGQLLVDATDFGDDVDPAEDPHGLLAAL
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
Mvan_0360|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0343|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4599|M.gilvum_PYR-GCK --------------------------------------------------
Mb2534|M.bovis_AF2122/97 --------------------------------------------------
Rv2506|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1669|M.avium_104 --------------------------------------------------
MMAR_3853|M.marinum_M --------------------------------------------------
MUL_3785|M.ulcerans_Agy99 --------------------------------------------------
MAB_2061c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2795|M.thermoresistible__bu VDALINVTIANRTAGGLYRWEGRYLREPDRDILERQIQLVNRRLQRPLRV
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
Mvan_0360|M.vanbaalenii_PYR-1 -----------------------------------------------MRT
MSMEG_0343|M.smegmatis_MC2_155 -----------------------------------------------MHS
Mflv_4599|M.gilvum_PYR-GCK -----------------------------------------------MNK
Mb2534|M.bovis_AF2122/97 ------------------------------------------------MT
Rv2506|M.tuberculosis_H37Rv ------------------------------------------------MT
MAV_1669|M.avium_104 --------------------------------------------------
MMAR_3853|M.marinum_M ------------------------------------------------MA
MUL_3785|M.ulcerans_Agy99 ------------------------------------------------MA
MAB_2061c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2795|M.thermoresistible__bu MRPELGSRQRWTLTASALSAIGSIADHSAPLSVPGIRSFLASVVEDLLAA
MLBr_00815|M.leprae_Br4923 ----------------------------------MNNLAKAAQRRTVRPI
Mvan_0360|M.vanbaalenii_PYR-1 N--------------ARTRDP-ERKSRIMAAAADLVARKGFHAVSIAEIG
MSMEG_0343|M.smegmatis_MC2_155 GGVLIVVDSPPGTAKARTRDP-DRKNRILLAASELIGRRGFHAVSIADIG
Mflv_4599|M.gilvum_PYR-GCK VVVA-----------GRTRVGGERRERILASATELIAERGYHAVSMADIG
Mb2534|M.bovis_AF2122/97 ASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIG
Rv2506|M.tuberculosis_H37Rv ASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIG
MAV_1669|M.avium_104 -------------------MKSDRRLQLLSAAERLFAERGFLAVRLEDIG
MMAR_3853|M.marinum_M ASAPDEQTATP---NRRSQQKSDRRLQLLSAAERLFAERGFLAVRLEDIG
MUL_3785|M.ulcerans_Agy99 ASAPDEQTATP---NRRSQQKSDRRLQLLSAAERLFAERGFLAVRLEDIG
MAB_2061c|M.abscessus_ATCC_199 -------------------MAGLRRKLLLEAAADLFARQGFHAVGIDDIG
TH_2795|M.thermoresistible__bu DLPTPRRRRAPDPPPPRVTLAAGIYECVLHESIQMFHERGFRDTGMDDIA
MLBr_00815|M.leprae_Br4923 DRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASDVFVDHGYHAAGMDEIA
:: : :. :*: . : :*.
Mvan_0360|M.vanbaalenii_PYR-1 AAAGITGSGIYRHFESKSAVLVALFDRVIDELLRDEQEILNTTDDLGQAL
MSMEG_0343|M.smegmatis_MC2_155 NAAGITGSGVYRHFESKSAILVALFDQVIDDLIAEEKRILDETDDLPTAL
Mflv_4599|M.gilvum_PYR-GCK VASGVVGPAIYRHFNSKSDLLAALFERVVDKLLKRATAIVEQSRDEAEAL
Mb2534|M.bovis_AF2122/97 AAAGVSGPAIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAAL
Rv2506|M.tuberculosis_H37Rv AAAGVSGPAIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAAL
MAV_1669|M.avium_104 ASAGVSGPAIYRHFPNKESLLVELLVGISTRLLAGARQVRARSADAAAAL
MMAR_3853|M.marinum_M AAAGISGPAIYRHFPNKESLLVELLVGISSRLLAGARQVTTNSNDAAAAL
MUL_3785|M.ulcerans_Agy99 AAAGISGPAIYRHFPNKESLLVELLVGISSRLLAGARQVTTNSNDAAAAL
MAB_2061c|M.abscessus_ATCC_199 AAAGVSGPAVYRHFQNKDAILRELCDAAMTELLAGARRATT-AGTPTEVL
TH_2795|M.thermoresistible__bu AAVGVPTTGIYRYFPGKADILAASLRRAVDRTSQDLARITAATADPHTAL
MLBr_00815|M.leprae_Br4923 DRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVSSVQQALRTTTNNRQRL
*: . :*::* .* : : *
Mvan_0360|M.vanbaalenii_PYR-1 DLLIAGQVEFVVADRELAQVYYNEINNLPEEDSRRLRRKQRLYLEEWVHL
MSMEG_0343|M.smegmatis_MC2_155 AELIEGQVEFVIGDRQLAQVYHNEINNLPEEDRRRLRRKQRLYLEEWVHL
Mflv_4599|M.gilvum_PYR-GCK TLLVSDQVALVMDQRELAMVYYREVHNLSDQHQSRLRRKQRLYLEEWVHL
Mb2534|M.bovis_AF2122/97 DGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWVGV
Rv2506|M.tuberculosis_H37Rv DGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWVGV
MAV_1669|M.avium_104 DGLIDFHLDFALNEPDLIRIQDRDLAYLPKPAERQVRKAQRQYVEVWVGV
MMAR_3853|M.marinum_M DGLIDFHLDFALGEPDLIRIQDRDLGHLPAAAERQVRKAQRQYVEIWVGV
MUL_3785|M.ulcerans_Agy99 DGLIDFHLDFALGEPDLIRIQDRDLGHLPAAAERQVRKAQRQYVEIWVGV
MAB_2061c|M.abscessus_ATCC_199 HALVDLHAAFGARRRGLLAVYAREHRSLSPLATRALRRRQHSYESFWVEA
TH_2795|M.thermoresistible__bu TQLVRAYLDQFRERPALAYVQHTERRNLPESEARVVERIEQSLVDSWARL
MLBr_00815|M.leprae_Br4923 HAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAAQVRVATESCIDAVFAL
: : : :. . .
Mvan_0360|M.vanbaalenii_PYR-1 VNESRVDLTDAEARTVVHAVIGAIQSPLFHN-TGLPEDRLRALLTDAARA
MSMEG_0343|M.smegmatis_MC2_155 VNELREDLDDTEARVIVHAAIGAIQSPLFHN-TGLADDRLRVLLADSARS
Mflv_4599|M.gilvum_PYR-GCK VGELRPAVDEIELRAMVHGAIGAIQSILHYRGTGLAPEQTSALLVAMGHA
Mb2534|M.bovis_AF2122/97 LRELNPGLAEADARLMAHAVFGLLNSTPHSM-KAADS---KPARTVRARA
Rv2506|M.tuberculosis_H37Rv LRELNPGLAEADARLMAHAVFGLLNSTPHSM-KAADS---KPARTVRARA
MAV_1669|M.avium_104 LRELNPELAEADARLTAHAVFGLLNSTPHSM-KSQDSGRGKPARAARSRA
MMAR_3853|M.marinum_M LRQLDPGLAEADARLMAHAAFGLLNSTPHSM-KSADT---KSACAPHSRA
MUL_3785|M.ulcerans_Agy99 LRQLDPGLAEADARLMAHAAFGLLNSTPHSM-ESADT---KSACAPHSRA
MAB_2061c|M.abscessus_ATCC_199 LVRARGDLDRERAQGLVAAVLSLLNASAYMP-ASLDDATIEAMLAAAAVA
TH_2795|M.thermoresistible__bu VTEQRPELTVATARYAVYCAFALVTDLGRLTDSHASPSAQAAVQHLMEVV
MLBr_00815|M.leprae_Br4923 IS-ADSRLDPHRARMVAVGLVGISVDCARYWLDTNRPISKSDAVEGTVQF
: : : . ..
Mvan_0360|M.vanbaalenii_PYR-1 VLGLDR----------------------
MSMEG_0343|M.smegmatis_MC2_155 ILSTDRRTP-------------------
Mflv_4599|M.gilvum_PYR-GCK VLGVPASSHQVRGVNTEPSCPRPGTPQH
Mb2534|M.bovis_AF2122/97 VLRAMTVAALSAADRCL-----------
Rv2506|M.tuberculosis_H37Rv VLRAMTVAALSAADRCL-----------
MAV_1669|M.avium_104 IMRAMTVAALAAGNQCP-----------
MMAR_3853|M.marinum_M VMRAMTVAALTVDVGA------------
MUL_3785|M.ulcerans_Agy99 VMRAMTVAALTVDVGA------------
MAB_2061c|M.abscessus_ATCC_199 ALFSRAVTQQVDGAPHRI----------
TH_2795|M.thermoresistible__bu LLGG------------------------
MLBr_00815|M.leprae_Br4923 AWGGLSHVPLTRL---------------