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KLGVMIGAERGDMARKVGKLVSDIEWAESAGLDTAWMPQVPNDFDCLTMVALMAAHTSRIELGTAVVPLQ AQHPIALARQALSVHAMAQGRLALGVGPSHHWIVRDMLGLPYEKPAAYTRDYLEVLNAALAGPGDVDVEN DTFTVHNPTVLGAEQPLPVLVAALGPVMLQIAGERADGTVLWMADEKAIGGHIAPKINKAAAEAGRPAPR IVAGIPVCLCANSEIDAAKDRANRILAEAETSPNYQKLLDRGDARSVGDLCAAGDEDAILARFKQFADAG VTDLSVRLLPIGETRDELVASKYRTREVIGELAKAVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4259 | - | - | 100% (318) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4198 | - | 3e-88 | 50.47% (319) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_0261 | - | 3e-41 | 31.51% (311) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | 3e-15 | 25.77% (291) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2389 | - | 1e-174 | 95.60% (318) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3093c | - | 4e-15 | 25.77% (291) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 4e-15 | 30.21% (192) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1339 | - | 7e-39 | 32.08% (318) | putative monooxygenase (luciferase-like) |
| M. marinum M | MMAR_4796 | - | 1e-139 | 75.16% (318) | oxidoreductase |
| M. avium 104 | MAV_0923 | - | 2e-97 | 53.14% (318) | hypothetical protein MAV_0923 |
| M. smegmatis MC2 155 | MSMEG_4879 | - | 1e-164 | 88.36% (318) | hypothetical protein MSMEG_4879 |
| M. thermoresistible (build 8) | TH_4355 | - | 1e-155 | 84.01% (319) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_0365 | - | 1e-139 | 74.84% (318) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4259|M.vanbaalenii_PYR-1 ---MKLGVMIGAERGDM--ARKVGKLVSDIEWAESAGLDTAWMPQVPNDF
Mflv_2389|M.gilvum_PYR-GCK ---MRLGVMIGAERGDM--ARKVSKLVSDIEWAESAGLDTAWMPQVPNDF
MSMEG_4879|M.smegmatis_MC2_155 ---MRLGVMIGAERGDM--TRKVNKLAADIQWAEAAGLDSAWMPQVPDDF
TH_4355|M.thermoresistible__bu ---MRVGVMIGAERGDM--ARKVRKFLEDIEWAESAGFDTAWMPQVPNDF
MMAR_4796|M.marinum_M ---MRVGVMIGPERGDS--GRKVGRMLADIDWAETAGLDSAWIPQIPNDF
MUL_0365|M.ulcerans_Agy99 ---MRVGVMIGPERGDS--GRKVGRMLADIDWAETAGLDSAWIPQIPNDF
MAV_0923|M.avium_104 ---MRIGLMVGSDKERSR-AERLAGLVDDAAAAERGGFTAFWMPQVPGYL
MAB_1339|M.abscessus_ATCC_1997 ---MKLGVAIGRPLSVQNSTNLVDTFIAHARRVAEAGVRTLWLGQMY-HY
Mb3120c|M.bovis_AF2122/97 ----MTDIEVALPFWLD---RPDHEATDVALAAADTGFAALWIGEMA-TY
Rv3093c|M.tuberculosis_H37Rv ----MTDIEVALPFWLD---RPDHEATDVALAAADTGFAALWIGEMA-TY
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWA-AQPPGNAAELVAAAEGAGFDAVFTGEAW-GS
: :. . . *. : : :
Mvan_4259|M.vanbaalenii_PYR-1 DCLTMVALMAAHTSRIELGTAVVPLQAQHPIALARQALSVHAMAQGRLAL
Mflv_2389|M.gilvum_PYR-GCK DCLTMVALMAAHTSRIELGTAVVPLQAQHPIALARQALSVHAMAAGRLAL
MSMEG_4879|M.smegmatis_MC2_155 DCLSMVALMAAHTSTIELGTAVVPLQAQHPVALARQALSVHAIAEGRLAL
TH_4355|M.thermoresistible__bu DALTMVALMATRTDRIELGTAVVPLQAQHPIALARQALSVHAGSGGRLAL
MMAR_4796|M.marinum_M DALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALSVHAATGGRLVL
MUL_0365|M.ulcerans_Agy99 DALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALSVHAATGGRLVL
MAV_0923|M.avium_104 DALTAVALIGQATERIEIGTAVVPIQTRHPMALAQQALTTQVACGGRFTL
MAB_1339|M.abscessus_ATCC_1997 DSITMAAVVGQTVPDVTVGVSVIPINPRHPIEVSAAAQTAQAATHGRFQL
Mb3120c|M.bovis_AF2122/97 DAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVDL
Rv3093c|M.tuberculosis_H37Rv DAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVDL
MLBr_00348|M.leprae_Br4923 DAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHIL
*. : . : : .. : : : * : . : * *
Mvan_4259|M.vanbaalenii_PYR-1 GVGPSHHWIVRDMLGLPYEKPAAYTRDYLEVLNAALAGPGDVDVENDTFT
Mflv_2389|M.gilvum_PYR-GCK GVGPSHHWIVRDMLGLPYEKPAAYTRDYLEVLNTALAGPGDVDVENDSFT
MSMEG_4879|M.smegmatis_MC2_155 GVGPSHHWIIRDMLGLPYDKPAAYTRDYLEVLNASLAGPGPVDVENDTFT
TH_4355|M.thermoresistible__bu GVGPSHHWIIRDMLGIPYERPAAYTRDYLEVLNAAIAGPGPVDVENDSFT
MMAR_4796|M.marinum_M GVGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANPGPVDVENDSFR
MUL_0365|M.ulcerans_Agy99 GVGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANPGPVDVENDSFR
MAV_0923|M.avium_104 GIGPSHHWIVNGQLGLPYERPARLTRNYLQVLGAAFAGPGSVDVDNESYC
MAB_1339|M.abscessus_ATCC_1997 GLGLGAPVIEGPSYGLHVDKPIRRLREYLITLRQLLD-AGTADFHGQTLT
Mb3120c|M.bovis_AF2122/97 ALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGAR-VEYSGRHVN
Rv3093c|M.tuberculosis_H37Rv ALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGAR-VEYSGRHVN
MLBr_00348|M.leprae_Br4923 GLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYP
.:* . : * : *: : : . .
Mvan_4259|M.vanbaalenii_PYR-1 V-----------HNPTVLG--AEQPLPVLVAALGPVMLQIAGERADGTVL
Mflv_2389|M.gilvum_PYR-GCK V-----------HNPTVLG--AEQPLPVLVAALGPVMLQIAGERADGTVL
MSMEG_4879|M.smegmatis_MC2_155 V-----------HNPTALA--AETPLPVLVAALGPVMLQIAGELADGTVL
TH_4355|M.thermoresistible__bu V-----------HNPTVLGT-DDTPMPVLVAALGPVMLQIAGELADGTVL
MMAR_4796|M.marinum_M V-----------HNPLDLA--AVAPLPVLVAALGPVMLTLAGERADGTVL
MUL_0365|M.ulcerans_Agy99 V-----------HNPLDLA--AVAPLPVLVAALGPVMLTLAGERADGTVL
MAV_0923|M.avium_104 V-----------HSPVDVT--DSFGVSILLSALGPTMLQLAGERADGTIL
MAB_1339|M.abscessus_ATCC_1997 V-----------APQFTTSQPGGENIPVLVAAMAPQALRATGELADGTIP
Mb3120c|M.bovis_AF2122/97 S-----------RGFRLRG--AAPDTRIALGAFGPGMIRLAAQHADEVVL
Rv3093c|M.tuberculosis_H37Rv S-----------RGFRLRG--AAPDTRIALGAFGPGMIRLAAQHADEVVL
MLBr_00348|M.leprae_Br4923 LPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLP
: :.* .* : :.: .* :
Mvan_4259|M.vanbaalenii_PYR-1 WMADEK---AIGGHIAPKINKAAAEAGRPAPRIVAGIPVCLCANSEIDAA
Mflv_2389|M.gilvum_PYR-GCK WMADEK---AIGEHIAPKITKAAADAGRPAPRIVAGIPVCLCANSEIDAA
MSMEG_4879|M.smegmatis_MC2_155 WMADER---AIGDHIAPRINKAADNAGRPAPRIVAGIPVCLCANSEIDTA
TH_4355|M.thermoresistible__bu WMADER---AIGEHIAPRITKAADNAGRPAPRIIAGIPVCLCANSEIEVA
MMAR_4796|M.marinum_M WMADER---AVAEHVVPRISKAADNAGRPAPRIVAGIPVCLCGSSEVEVA
MUL_0365|M.ulcerans_Agy99 WMADER---AVAEHVVPRISKAADNAGRPVPRIVAGIPVCLCGSSEVEVA
MAV_0923|M.avium_104 WMADER---AIGEHVVPRITAAAGGAGRPAPRVVAGVPVAVCSNSEIDDA
MAB_1339|M.abscessus_ATCC_1997 LHAGPR---ALGQEVVPVISAAAERAGRPRPRVIAGVAVVVTS--EPERV
Mb3120c|M.bovis_AF2122/97 NLASPF---RVG-RVRAAIDSAAAAAGRAAPRLTVWVPVAVNPGAAAHSQ
Rv3093c|M.tuberculosis_H37Rv NLASPF---RVG-RVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQ
MLBr_00348|M.leprae_Br4923 IFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDRAAAFA
. : : :. .* .: . : :
Mvan_4259|M.vanbaalenii_PYR-1 KDRAN-------------------RILAEAETSPNYQKLLDRGDARSVGD
Mflv_2389|M.gilvum_PYR-GCK KDRAN-------------------RILAEAETSPNYQRLLDRGDARNVGD
MSMEG_4879|M.smegmatis_MC2_155 KERAN-------------------RILAEAETSPNYQRLLDRGDARNVGD
TH_4355|M.thermoresistible__bu KERAN-------------------RILGEAEVSPNYQRLLERGDARDVGD
MMAR_4796|M.marinum_M RDRAN-------------------RILGEAEVSPNYQRLLGYGDAKDVGD
MUL_0365|M.ulcerans_Agy99 RDRAN-------------------RILGEAEVSPNYQRLLGHGDAKDVGD
MAV_0923|M.avium_104 RAYAG-------------------EMLGHAEFSPNYVRLLQHGDAEDVGD
MAB_1339|M.abscessus_ATCC_1997 RALAI-------------------EDMAFYENIPSYRKVLDAEGVQHTGE
Mb3120c|M.bovis_AF2122/97 LAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDR
Rv3093c|M.tuberculosis_H37Rv LAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDR
MLBr_00348|M.leprae_Br4923 GIKPFLALYMGG-----------MGAEGTNFHADVYRRMGYAEVVDEVTA
.:
Mvan_4259|M.vanbaalenii_PYR-1 LCAAGDEDAILARFK------QFADAGVTDLSVRLLPIGETRDELVASKY
Mflv_2389|M.gilvum_PYR-GCK LCAAGDEESILARFK------QFADAGVTDLSVRLLPIGETRDELVASKY
MSMEG_4879|M.smegmatis_MC2_155 LCAAGDEDAILARFK------RFADAGVTDLSVRLLPIGDNRDELIASKY
TH_4355|M.thermoresistible__bu LCAAGDEEAIMARFR------RFADAGVTDLSVRLLPIGETRDELVASKY
MMAR_4796|M.marinum_M ICAAGDEDAILARFR------RFAEAGVTDLSVRLLPIGDNREELVASKR
MUL_0365|M.ulcerans_Agy99 ICAAGDEDAILARFR------RFAEAGVTDLSVRLLPIGDNREELVASKR
MAV_0923|M.avium_104 TMAAGDESAVLRRLR------RYRDAGATDLAARIVPLGNDARERAESRR
MAB_1339|M.abscessus_ATCC_1997 LAIIGDEQHVATELQ------RYFDAGATEVFASHTELGGPQD-----EA
Mb3120c|M.bovis_AF2122/97 VCALGSPDRVAARLR------AYADAGADCVAVVPATAEDPGGRVALRAL
Rv3093c|M.tuberculosis_H37Rv VCALGSPDRVAARLR------AYADAGADCVAVVPATAEDPGGRVALRAL
MLBr_00348|M.leprae_Br4923 LFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSA
.. . : ... :
Mvan_4259|M.vanbaalenii_PYR-1 RTREVIGELAKAVR--
Mflv_2389|M.gilvum_PYR-GCK RTREVIGELAKAVQ--
MSMEG_4879|M.smegmatis_MC2_155 RTREVIAELAKAVR--
TH_4355|M.thermoresistible__bu RTREVIAQLAADLR--
MMAR_4796|M.marinum_M RTRDMIATLATEVR--
MUL_0365|M.ulcerans_Agy99 RTRDMIATLATEVR--
MAV_0923|M.avium_104 RTHEFLSAVCPAL---
MAB_1339|M.abscessus_ATCC_1997 RTLALLGELSRGN---
Mb3120c|M.bovis_AF2122/97 RPGGLYGTAGDNDGRR
Rv3093c|M.tuberculosis_H37Rv RPGGLYGTAGDNDGRR
MLBr_00348|M.leprae_Br4923 SSVEQVRDLAGLF---
.