For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRIGLMVGSDRDRPRPDRLDGVITDGTAAEALGFSSFWFPQVPGYLDAMTALALLGASTTTIELGTAVVP IQTRHPMILAQQGLTTNAACGGRFTLGLGLSHDWIINGQLGIPYQRPVRELRDHLEVLTAAFDGPGQVDV DNDSFRVHSPVDVSDLSPPVLLAALGPTMLRIAGERTDGTILWMADERAIAEHVAPRITAAAHAAGRPAP RVVAGVPVAVCAPGDVDAAQRYASELLGHAHFSPNYVALLEHGDAADVGDTMAAGDESCVLNRLRAYRDA GVTDLAARIVPLGDDPASRRRSRERTAEFLASVVSEF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4198 | - | - | 100% (317) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4259 | - | 3e-88 | 50.47% (319) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_0261 | - | 9e-44 | 38.83% (273) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | 1e-17 | 29.45% (309) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2453 | - | 1e-150 | 80.95% (315) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3093c | - | 2e-17 | 29.45% (309) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 6e-16 | 26.04% (338) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1339 | - | 3e-35 | 33.00% (297) | putative monooxygenase (luciferase-like) |
| M. marinum M | MMAR_4796 | - | 6e-96 | 53.14% (318) | oxidoreductase |
| M. avium 104 | MAV_0923 | - | 1e-129 | 71.34% (314) | hypothetical protein MAV_0923 |
| M. smegmatis MC2 155 | MSMEG_4879 | - | 1e-90 | 52.35% (319) | hypothetical protein MSMEG_4879 |
| M. thermoresistible (build 8) | TH_2809 | - | 1e-128 | 72.87% (317) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0365 | - | 2e-96 | 53.14% (318) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4198|M.vanbaalenii_PYR-1 --MRIGLMVG-SDRDRPRPDRLDGVITDGTAAEALGFSSFWFPQVPGYLD
Mflv_2453|M.gilvum_PYR-GCK --MRIGLMVG-SDRERARPDRLAGLIEDGIAAETAGFNSFWFPQVPGYLD
TH_2809|M.thermoresistible__bu --MRIGLMVG-SDKERSRADRLTGLLDDGRAAEADGFASFWMPQVPGYLD
MAV_0923|M.avium_104 --MRIGLMVG-SDKERSRAERLAGLVDDAAAAERGGFTAFWMPQVPGYLD
MMAR_4796|M.marinum_M --MRVGVMIG-PERGDS-GRKVGRMLADIDWAETAGLDSAWIPQIPNDFD
MUL_0365|M.ulcerans_Agy99 --MRVGVMIG-PERGDS-GRKVGRMLADIDWAETAGLDSAWIPQIPNDFD
MSMEG_4879|M.smegmatis_MC2_155 --MRLGVMIG-AERGDM-TRKVNKLAADIQWAEAAGLDSAWMPQVPDDFD
MAB_1339|M.abscessus_ATCC_1997 --MKLGVAIGRPLSVQNSTNLVDTFIAHARRVAEAGVRTLWLGQMY-HYD
Mb3120c|M.bovis_AF2122/97 ---MTDIEVALPFWLDRPDHEAT---DVALAAADTGFAALWIGEMA-TYD
Rv3093c|M.tuberculosis_H37Rv ---MTDIEVALPFWLDRPDHEAT---DVALAAADTGFAALWIGEMA-TYD
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAW-GSD
. . *. : : : *
Mvan_4198|M.vanbaalenii_PYR-1 AMTALALLGASTTTIELGTAVVPIQTRHPMILAQQGLTTNAACGGRFTLG
Mflv_2453|M.gilvum_PYR-GCK AMTTVALLGASTSSIEIGTAVIPVQTRHPLILAQQALTTNAACGGRFALG
TH_2809|M.thermoresistible__bu ALTAVALLGQRTKRIEIGTAVVPVQTRHPLIMAQQALTTQAACNGRFTLG
MAV_0923|M.avium_104 ALTAVALIGQATERIEIGTAVVPIQTRHPMALAQQALTTQVACGGRFTLG
MMAR_4796|M.marinum_M ALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALSVHAATGGRLVLG
MUL_0365|M.ulcerans_Agy99 ALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALSVHAATGGRLVLG
MSMEG_4879|M.smegmatis_MC2_155 CLSMVALMAAHTSTIELGTAVVPLQAQHPVALARQALSVHAIAEGRLALG
MAB_1339|M.abscessus_ATCC_1997 SITMAAVVGQTVPDVTVGVSVIPINPRHPIEVSAAAQTAQAATHGRFQLG
Mb3120c|M.bovis_AF2122/97 AFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVDLA
Rv3093c|M.tuberculosis_H37Rv AFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVDLA
MLBr_00348|M.leprae_Br4923 AYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILG
. : . : : .. : : : * : : * *.
Mvan_4198|M.vanbaalenii_PYR-1 LGLSHDWIINGQLGIPYQRPVRELRDHLEVLTAAFDGPGQVDVDNDSFRV
Mflv_2453|M.gilvum_PYR-GCK LGLSHDWIINGQLGLPYQRPVHTLRDHLDVLAAAFAGPGQVDVDNDTFHV
TH_2809|M.thermoresistible__bu LGPSHHWIIADQLGLPYDRPAALMRDYLDVLIAAFAGPGAVAVTNDSFRV
MAV_0923|M.avium_104 IGPSHHWIVNGQLGLPYERPARLTRNYLQVLGAAFAGPGSVDVDNESYCV
MMAR_4796|M.marinum_M VGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANPGPVDVENDSFRV
MUL_0365|M.ulcerans_Agy99 VGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANPGPVDVENDSFRV
MSMEG_4879|M.smegmatis_MC2_155 VGPSHHWIIRDMLGLPYDKPAAYTRDYLEVLNASLAGPGPVDVENDTFTV
MAB_1339|M.abscessus_ATCC_1997 LGLGAPVIEGPSYGLHVDKPIRRLREYLITLRQLLD-AGTADFHGQTLTV
Mb3120c|M.bovis_AF2122/97 LGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSR
Rv3093c|M.tuberculosis_H37Rv LGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSR
MLBr_00348|M.leprae_Br4923 LGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPL
:* . : * : *: : : .
Mvan_4198|M.vanbaalenii_PYR-1 HSP-----------VDVSDLS---PPVLLAALGPTMLRIAGERTDGTILW
Mflv_2453|M.gilvum_PYR-GCK HSP-----------VDVADTA---PALLLAALGPTMLRIAGERADGTVLW
TH_2809|M.thermoresistible__bu CSP-----------IDVTDATG--PPVLIAALGPTMLRIAGERTGGTILW
MAV_0923|M.avium_104 HSP-----------VDVTDSFG--VSILLSALGPTMLQLAGERADGTILW
MMAR_4796|M.marinum_M HNP-----------LDLAAVAP--LPVLVAALGPVMLTLAGERADGTVLW
MUL_0365|M.ulcerans_Agy99 HNP-----------LDLAAVAP--LPVLVAALGPVMLTLAGERADGTVLW
MSMEG_4879|M.smegmatis_MC2_155 HNP-----------TALAAETP--LPVLVAALGPVMLQIAGELADGTVLW
MAB_1339|M.abscessus_ATCC_1997 APQ-----------FTTSQPGGENIPVLVAAMAPQALRATGELADGTIPL
Mb3120c|M.bovis_AF2122/97 GFR-----------LRGAAPDT---RIALGAFGPGMIRLAAQHADEVVLN
Rv3093c|M.tuberculosis_H37Rv GFR-----------LRGAAPDT---RIALGAFGPGMIRLAAQHADEVVLN
MLBr_00348|M.leprae_Br4923 PLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPI
: : :.* .* : :.: . :
Mvan_4198|M.vanbaalenii_PYR-1 MADERAIAEH---VAPRITAAAHAAGRPAPRVVAGVPVAVCAPGDVDAAQ
Mflv_2453|M.gilvum_PYR-GCK MADERAIGEH---VVPRIGAAAQGAGRPAPRVVAGVPVALCEPADVDDAR
TH_2809|M.thermoresistible__bu MADERAIGEY---VVPRITAAAERAGRHGIRVVAGVPVALCADRDVDAAR
MAV_0923|M.avium_104 MADERAIGEH---VVPRITAAAGGAGRPAPRVVAGVPVAVCSNSEIDDAR
MMAR_4796|M.marinum_M MADERAVAEH---VVPRISKAADNAGRPAPRIVAGIPVCLCGSSEVEVAR
MUL_0365|M.ulcerans_Agy99 MADERAVAEH---VVPRISKAADNAGRPVPRIVAGIPVCLCGSSEVEVAR
MSMEG_4879|M.smegmatis_MC2_155 MADERAIGDH---IAPRINKAADNAGRPAPRIVAGIPVCLCANSEIDTAK
MAB_1339|M.abscessus_ATCC_1997 HAGPRALGQE---VVPVISAAAERAGRPRPRVIAGVAVVVTS--EPERVR
Mb3120c|M.bovis_AF2122/97 LASPFRVGR----VRAAIDSAAAAAGRAAPRLTVWVPVAVNPGAAAHSQL
Rv3093c|M.tuberculosis_H37Rv LASPFRVGR----VRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQL
MLBr_00348|M.leprae_Br4923 FFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDRAAAFAG
. : : :. .* .: . : :
Mvan_4198|M.vanbaalenii_PYR-1 RYASELLGHA-------HFSPNYVALLEHGDAADVG--------------
Mflv_2453|M.gilvum_PYR-GCK AHASEILGHA-------HLSPNYVALLEHGDADDVG--------------
TH_2809|M.thermoresistible__bu AYASEVLGHA-------DVSPNYVRLLEHGDAADVG--------------
MAV_0923|M.avium_104 AYAGEMLGHA-------EFSPNYVRLLQHGDAEDVG--------------
MMAR_4796|M.marinum_M DRANRILGEA-------EVSPNYQRLLGYGDAKDVG--------------
MUL_0365|M.ulcerans_Agy99 DRANRILGEA-------EVSPNYQRLLGHGDAKDVG--------------
MSMEG_4879|M.smegmatis_MC2_155 ERANRILAEA-------ETSPNYQRLLDRGDARNVG--------------
MAB_1339|M.abscessus_ATCC_1997 ALAIEDMAFY-------ENIPSYRKVLDAEGVQHTG--------------
Mb3120c|M.bovis_AF2122/97 AAQLAVYLAP-------PGYGEMFSALGFDGLVRSARSRATRRELAVAVP
Rv3093c|M.tuberculosis_H37Rv AAQLAVYLAP-------PGYGEMFSALGFDGLVRSARSRATRRELAVAVP
MLBr_00348|M.leprae_Br4923 IKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVT-------------
. :
Mvan_4198|M.vanbaalenii_PYR-1 -----DTMAAGDESCVLNRLR------AYRDAGVTDLAARIVPLGDDPAS
Mflv_2453|M.gilvum_PYR-GCK -----DTMAAGDESAVLTRLR------AYRDAGVTDLAARVIPLGDTPAR
TH_2809|M.thermoresistible__bu -----DTMAAGDEAAVRARLR------RYRDAGVTDLAVRVVPLGTDAGR
MAV_0923|M.avium_104 -----DTMAAGDESAVLRRLR------RYRDAGATDLAARIVPLGNDARE
MMAR_4796|M.marinum_M -----DICAAGDEDAILARFR------RFAEAGVTDLSVRLLPIGDNREE
MUL_0365|M.ulcerans_Agy99 -----DICAAGDEDAILARFR------RFAEAGVTDLSVRLLPIGDNREE
MSMEG_4879|M.smegmatis_MC2_155 -----DLCAAGDEDAILARFK------RFADAGVTDLSVRLLPIGDNRDE
MAB_1339|M.abscessus_ATCC_1997 -----ELAIIGDEQHVATELQ------RYFDAGATEVFASHTELGGPQDE
Mb3120c|M.bovis_AF2122/97 SELLDRVCALGSPDRVAARLR------AYADAGADCVAVVPATAEDPGGR
Rv3093c|M.tuberculosis_H37Rv SELLDRVCALGSPDRVAARLR------AYADAGADCVAVVPATAEDPGGR
MLBr_00348|M.leprae_Br4923 -----ALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVT
.. : ... :
Mvan_4198|M.vanbaalenii_PYR-1 RRRSRERTAEFLASVVSEF---
Mflv_2453|M.gilvum_PYR-GCK RHQSRRRTAEFLASVAAGL---
TH_2809|M.thermoresistible__bu RAASRRRTQEFVVSLVDELS--
MAV_0923|M.avium_104 RAESRRRTHEFLSAVCPAL---
MMAR_4796|M.marinum_M LVASKRRTRDMIATLATEVR--
MUL_0365|M.ulcerans_Agy99 LVASKRRTRDMIATLATEVR--
MSMEG_4879|M.smegmatis_MC2_155 LIASKYRTREVIAELAKAVR--
MAB_1339|M.abscessus_ATCC_1997 -----ARTLALLGELSRGN---
Mb3120c|M.bovis_AF2122/97 VALRALRPGGLYGTAGDNDGRR
Rv3093c|M.tuberculosis_H37Rv VALRALRPGGLYGTAGDNDGRR
MLBr_00348|M.leprae_Br4923 MMMVSASSVEQVRDLAGLF---
.