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PPAYQVLRERLRDDIAAGRYPDGTRLPTESELVARHGLSRQTVRRAFQDLVAEGTVYRVPGRGSYASEQG RRYLRQLGSIEDLMSLSDDTTMEVVDGLRRRVDIEAASRLRLDGDVVYSVQFRRLHGGIAFGHTTVALPP AVATSVLTSPHLVTGATSTHTVIGLLEPHLEKPIAEAAQSITVAAADEAAAAAVACPPGHPMLRVDRLYA DDEGHPVELAVSQFLPEQYTYRVTLRRSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0220 | - | - | 100% (240) | regulatory protein GntR, HTH |
| M. vanbaalenii PYR-1 | Mvan_4965 | - | 3e-11 | 26.03% (242) | regulatory protein GntR, HTH |
| M. vanbaalenii PYR-1 | Mvan_3927 | - | 2e-10 | 23.83% (235) | UbiC transcription regulator-associated domain-containing |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 2e-20 | 32.39% (247) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0447 | - | 1e-117 | 88.28% (239) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0792c | - | 2e-20 | 32.39% (247) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2239 | - | 9e-14 | 29.41% (238) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2560 | - | 3e-16 | 30.25% (238) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0738 | - | 8e-18 | 30.92% (249) | mercuric reductase/transcriptional regulator, fusion |
| M. smegmatis MC2 155 | MSMEG_5630 | - | 3e-13 | 26.03% (242) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_4188 | - | 2e-93 | 74.15% (236) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 1e-15 | 31.12% (241) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0220|M.vanbaalenii_PYR-1 ---------------------MP-PAYQVLRERLRDDIAAGRYPDGTRLP
Mflv_0447|M.gilvum_PYR-GCK ---------------------MP-PAYQVLRERLRDEIAAGCYPDGTRLP
TH_4188|M.thermoresistible__bu --------------------VRPRPAYQVLRDRLRDDIAAGRYRDGTRLP
Mb0816c|M.bovis_AF2122/97 MTSVK----LDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv MTSVK----LDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MAV_0738|M.avium_104 MVPDQ----LDLDAADLRISRGSVPASTQLAEALKAAIVKQRLPRGARLP
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MAB_2239|M.abscessus_ATCC_1997 ----------MAAAEPTPLRRPRADQARLVADVLRHQIHAGGYAEGG-LP
MSMEG_5630|M.smegmatis_MC2_155 -----------------MTVSPAEHRYLQVARTLRKEIVDGVYPVGSHLP
: *: * * **
Mvan_0220|M.vanbaalenii_PYR-1 TESELVARHGLSRQTVRRAFQDLVAEGTVYRVPGRGSYASEQ--GRRYLR
Mflv_0447|M.gilvum_PYR-GCK TESELVARLGLSRQTVRRAFQDLVAEGAVYRVPGRGSYAGDR--GRRYLR
TH_4188|M.thermoresistible__bu TESELMAQYGVSRQTVRRAFQDLVAEGSVYRVPGRGTYAAD-----RYLR
Mb0816c|M.bovis_AF2122/97 SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADP--VEQELS
Rv0792c|M.tuberculosis_H37Rv SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADP--VEQELS
MAV_0738|M.avium_104 TERELVDRTRVSRVTVRAAVGLLERQGWLVRRQGLGTFVANP--VKQELG
MMAR_2560|M.marinum_M TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLGTFVAEP--VKQDLE
MUL_3201|M.ulcerans_Agy99 TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLGTFVAEP--VEQDLE
MAB_2239|M.abscessus_ATCC_1997 SEHALAAEFFVSRNTVREALTTLKDEGLIERGPRTGTHVALRK-YEHGLD
MSMEG_5630|M.smegmatis_MC2_155 TEHELCERFEVSRYTIREALRRLRDDNLVESRPRAGTTVVPRPTTNSYAQ
:* * . :** *:* *. * :. : *: .
Mvan_0220|M.vanbaalenii_PYR-1 QLGSIEDLMSLSDDTTMEVVDGLRRRVDIEAASRLRLDG-DVVYSVQFRR
Mflv_0447|M.gilvum_PYR-GCK QLGSIEDLLSLSEDTTMEVLDGLRRRVDIDAASRLRLDG-DVVYTVVFRR
TH_4188|M.thermoresistible__bu QFGSIEDLMALSDDTTMEVRSGLRRRVDVDAASRLRLDD-DVVHTVVFRR
Mb0816c|M.bovis_AF2122/97 CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL-VEVLCIRRRI
Rv0792c|M.tuberculosis_H37Rv CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL-VEVLCIRRRI
MAV_0738|M.avium_104 PGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLHL-TKVLCVHRRF
MMAR_2560|M.marinum_M SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGR-SEVLRIQRRY
MUL_3201|M.ulcerans_Agy99 SGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGR-SEVLRIQRRY
MAB_2239|M.abscessus_ATCC_1997 ALLGLKETFKGYGEVRNEVRVIQEVNAPPAVAHRLRLDPGARVIFIERLR
MSMEG_5630|M.smegmatis_MC2_155 DVMSINDLLAFATGAQFTIDSNAMVTIDDELAERTGLPVDEEWLAVRGYR
. : * :
Mvan_0220|M.vanbaalenii_PYR-1 LHGGI--AFGHTTVALPPAVATSVLTSPHLVTGATSTHT------VIGLL
Mflv_0447|M.gilvum_PYR-GCK LHDGI--AFGHTMVHLPPAVAAPVLASPHLMTGAVSTHT------VIGLL
TH_4188|M.thermoresistible__bu LHAGA--PFVSTVVHLPDRAAHHLHGCAELRTGAVSTHT------VIGLL
Mb0816c|M.bovis_AF2122/97 RTGDQ--PLALVTAYLPPGVG---PAVEPLLSGSADTET------TYAMW
Rv0792c|M.tuberculosis_H37Rv RTGDQ--PLALVTAYLPPGVG---PAVEPLLSGSADTET------TYAMW
MAV_0738|M.avium_104 RDGEQ--PLALMIAYLPPGLG---EAVEPLLKSATDTQTGRAMESTYTMW
MMAR_2560|M.marinum_M SESDQ--PLAIVTCYLPADLPH--DAVEPLLSATSATAT------TYTMW
MUL_3201|M.ulcerans_Agy99 SESDQ--PLAIVTCYLPTDLPH--DAVEPLLSATSVTAT------TYTMW
MAB_2239|M.abscessus_ATCC_1997 YLGDL--PLSLDKTYLTPDVG------EAVIEHQLETND------VFALI
MSMEG_5630|M.smegmatis_MC2_155 QAEGNKPPVCRTEYYINRSFA--------AVGRLLQRHTG----PIFPLI
.. : :
Mvan_0220|M.vanbaalenii_PYR-1 EPHLEKPIAEAAQSITVAAADEAAAAAVACPPGHPMLRVDRLYADDEGHP
Mflv_0447|M.gilvum_PYR-GCK EPHLERPIDEAAQSITVVSADEAAAAAVHCAPGHPMLRVDRLYADDEGRP
TH_4188|M.thermoresistible__bu EPHLEEPIDQAAQSITVAPADDDTADAVGVEPGHPMLRIDRLYSDRTGRP
Mb0816c|M.bovis_AF2122/97 ERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKP
Rv0792c|M.tuberculosis_H37Rv ERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKP
MAV_0738|M.avium_104 ERRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLERTSYGHDDTP
MMAR_2560|M.marinum_M EQRLGVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKP
MUL_3201|M.ulcerans_Agy99 EQRLGVRISSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKP
MAB_2239|M.abscessus_ATCC_1997 ERVTGRRLGSANLALEAVAADSHSAATLQVPDSAPLLLLERLTHLDDGTP
MSMEG_5630|M.smegmatis_MC2_155 EDLFGVSVVEVHQQITAVLVDTDLAELLKVSPGTAALQMQRTYTTSDGEI
* : . : .. .. * : . . * : * .
Mvan_0220|M.vanbaalenii_PYR-1 VELAVSQFLPEQYTYRVTLRRSS--------------
Mflv_0447|M.gilvum_PYR-GCK VELAVSQFLPEQYTYRVTLRRSG--------------
TH_4188|M.thermoresistible__bu VELSVSHFLPEQYTYRVTLRRE---------------
Mb0816c|M.bovis_AF2122/97 LEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
Rv0792c|M.tuberculosis_H37Rv LEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
MAV_0738|M.avium_104 LEVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG--
MMAR_2560|M.marinum_M LEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER----
MUL_3201|M.ulcerans_Agy99 LEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER----
MAB_2239|M.abscessus_ATCC_1997 VDLEYIRMRGDRITLRSNLLRDI--------------
MSMEG_5630|M.smegmatis_MC2_155 AQVTVNTHPSGRYRHSMTMRRVKG-------------
:: : .: *