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VRALPHKIAVITGGASGIGAGTARRFLAEGARVVIADIDRERGEARAAELGPDCVFKYTDVASRDDVTEL VEYAVDRFGGLDVMMNNAGISGRMQPELLDDDFADFDRVMRVDLLGVMLGTQIAARHMKDHGGGSIINTT SIGGIQAGCTVMTYRAAKAGVIHFTKSAAIDLAQYAIRVNTIAPGGIPTAILSAATGVDESDELGTTAAI RKEIAAERPLKMTASVDDIAAAAAYLGSEDARYVTGVVLPVDGGMTAGNPRNPLRDLMIAAH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0169 | - | - | 100% (273) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4237 | - | 2e-76 | 58.59% (256) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_3000 | - | 2e-36 | 37.21% (258) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 6e-42 | 40.47% (257) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2415 | - | 2e-74 | 56.76% (259) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1350 | fabG | 6e-42 | 40.47% (257) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-26 | 31.47% (251) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4680c | - | 6e-38 | 37.65% (255) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4765 | - | 9e-82 | 61.15% (260) | short chain dehydrogenase |
| M. avium 104 | MAV_0886 | - | 6e-80 | 60.77% (260) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_4859 | - | 7e-77 | 57.03% (256) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. thermoresistible (build 8) | TH_3420 | - | 2e-79 | 60.16% (256) | PUTATIVE oxidoreductase, short chain dehydrogenase/reductase |
| M. ulcerans Agy99 | MUL_0336 | - | 3e-82 | 61.15% (260) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1385|M.bovis_AF2122/97 --------------MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVL
Rv1350|M.tuberculosis_H37Rv --------------MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVL
MSMEG_4859|M.smegmatis_MC2_155 ---------------MSELAGRVAVVTGGASGLGEGLVRRFVAEGAQVMI
TH_3420|M.thermoresistible__bu -----------VTERAGELAGKVAVVTGGAAGLGAGLARRFVAEGAKVLI
Mflv_2415|M.gilvum_PYR-GCK ---------------MTELAGKVAVVTGGASGIGRGIAARFAAEGAAVVI
MMAR_4765|M.marinum_M --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MUL_0336|M.ulcerans_Agy99 --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MAV_0886|M.avium_104 --------------MVNELAGKVAIVTGGASGIGRGIVERFVAEGARVVI
Mvan_0169|M.vanbaalenii_PYR-1 --------------MVRALPHKIAVITGGASGIGAGTARRFLAEGARVVI
MAB_4680c|M.abscessus_ATCC_199 -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: : ::*** *:* . :: ::* * :
Mb1385|M.bovis_AF2122/97 GDVNLEATEVAAKRLG--GDDVALAVRCDVTQADDVDILIRTAVERFGGL
Rv1350|M.tuberculosis_H37Rv GDVNLEATEVAAKRLG--GDDVALAVRCDVTQADDVDILIRTAVERFGGL
MSMEG_4859|M.smegmatis_MC2_155 GDVDKDRGTALAEEL---GAHTEFLT-TDVADQEQVAALVSAGVERFGGL
TH_3420|M.thermoresistible__bu GDVDTGNGAKLAAEL---GADAEFVE-ADVADLDQVSGLVSTAVERFGGL
Mflv_2415|M.gilvum_PYR-GCK ADVRDDLGEALVRELNESGAKTVYRH-TDVGDQAQVADLVSSTVETFGAL
MMAR_4765|M.marinum_M ADVEEERGESLAAAL---GADAMFCR-TDVSQPEQVAAVVAAAVENFGGL
MUL_0336|M.ulcerans_Agy99 ADVEEERGESLAAAL---GADAMFCR-TDVSQPEQVAAVVAAAVDNFGGL
MAV_0886|M.avium_104 ADIETERGERLAAEL---GGEAVFRR-TDVSDIEQVGALVAAAVEKFGGL
Mvan_0169|M.vanbaalenii_PYR-1 ADIDRERGEARAAEL---GPDCVFKY-TDVASRDDVTELVEYAVDRFGGL
MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGRQLAAEL---GDAARFTH-LDVTDAEQWRELIDTTLAGFGTI
MLBr_01807|M.leprae_Br4923 THRASVVP------------DWFFGVECDVTDNDAIGAAFKAVEEHQGPV
. ** . . * :
Mb1385|M.bovis_AF2122/97 DVMVNNAGITRDATMRTMTE--EQFDQVIAVHLKGTWNGTRLAAAIMRER
Rv1350|M.tuberculosis_H37Rv DVMVNNAGITRDATMRTMTE--EQFDQVIAVHLKGTWNGTRLAAAIMRER
MSMEG_4859|M.smegmatis_MC2_155 HVMVNNAGVSGTMHRRFLDDDLADFHKVMGVNVLGVMAGTREAARYMADN
TH_3420|M.thermoresistible__bu HVMVNNAGISGTMHRSLLDDDLADFDRVMRINVRAVMAGTRDAARHMAEH
Mflv_2415|M.gilvum_PYR-GCK NVMVNNAGISSPLRKGLFHEDLEEFDRVMRVNLLGVMAGTRDAARHMADH
MMAR_4765|M.marinum_M HVMVNNAGVSGVMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAH
MUL_0336|M.ulcerans_Agy99 HVMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAH
MAV_0886|M.avium_104 HVMVNNAGISSPLRR-LLDDDLADFHRVMGVNVLGVMAGTRDAARHMADN
Mvan_0169|M.vanbaalenii_PYR-1 DVMMNNAGISGRMQPELLDDDFADFDRVMRVDLLGVMLGTQIAARHMKDH
MAB_4680c|M.abscessus_ATCC_199 TGLVNNAGISS--AAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAH
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMRMSE--EQFQKVIDVNLTGVFRVAKLASRNMIKQ
:: ***:: : .* :*: :.: .. : . * .
Mb1385|M.bovis_AF2122/97 KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNA
Rv1350|M.tuberculosis_H37Rv KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNA
MSMEG_4859|M.smegmatis_MC2_155 GGGSILNLTSIGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHHEIRVNA
TH_3420|M.thermoresistible__bu GGGSIINLTSIGGIQAGGGVQTYRASKAAVIQFTKSAAIELAHHEIRVNA
Mflv_2415|M.gilvum_PYR-GCK GGGSVINLGSIGGIQAGGGVSTYRASKAAIIHFTKCAAIELAHYEVRVNC
MMAR_4765|M.marinum_M GGGSIVNLTSIGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHYEIRVNA
MUL_0336|M.ulcerans_Agy99 GGGSIVNLTSIGGIQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRVNA
MAV_0886|M.avium_104 GGGAIINLTSIGGIQAGGGVMTYRASKAAVIQFTKAAAIELARYDIRVNA
Mvan_0169|M.vanbaalenii_PYR-1 GGGSIINTTSIGGIQAGCTVMTYRAAKAGVIHFTKSAAIDLAQYAIRVNT
MAB_4680c|M.abscessus_ATCC_199 GCGSIVNISSAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNS
MLBr_01807|M.leprae_Br4923 RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
* : * * . * *:* .: ::: * :*. : .*
Mb1385|M.bovis_AF2122/97 IAPGLIRS------------AMTEAMPQRIWDQKLAEVPMGRAGEPSEVA
Rv1350|M.tuberculosis_H37Rv IAPGLIRS------------AMTEAMPQRIWDQKLAEVPMGRAGEPSEVA
MSMEG_4859|M.smegmatis_MC2_155 IAPGNIRTAIVAKSASEEDRQRIEEFEANIRAQMRADRPLKREGTVEDVA
TH_3420|M.thermoresistible__bu LAPGNIRTAIVRKSATGADLERLERFEARIRQQMRDDRPLKREGTVEDVA
Mflv_2415|M.gilvum_PYR-GCK LAPGNIPTPILASSATDEDRERLEKFEARIRQQMRDDRPLKREGTADDVA
MMAR_4765|M.marinum_M IAPGNIPTPLLASSAAGMDQEQVERFTAQIRQTMREDRPLKREGTPEDIA
MUL_0336|M.ulcerans_Agy99 IAPGNIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKREGTPEDIA
MAV_0886|M.avium_104 IAPGNIPTPILGKSAGDMDPEQRERFEARIREGMREDRPLKREGTPDDVA
Mvan_0169|M.vanbaalenii_PYR-1 IAPGGIPTAILS-AATGVDESDELGTTAAIRKEIAAERPLKMTASVDDIA
MAB_4680c|M.abscessus_ATCC_199 VHPGVIYTP----------MTAKEGFRE--GEGNMPIAAMGRVGNADEVA
MLBr_01807|M.leprae_Br4923 VAPGFIDT------------EMTRAMDSKYQEAALQAIPLGRIGAVEEIA
: ** * : .: . .::*
Mb1385|M.bovis_AF2122/97 SVAVFLASDLSSYMTGTVLDVTGGRFI---------------
Rv1350|M.tuberculosis_H37Rv SVAVFLASDLSSYMTGTVLDVTGGRFI---------------
MSMEG_4859|M.smegmatis_MC2_155 EAALYFATDRSRYVTGTVLPIDGGTVAGKVIVRKEKR-----
TH_3420|M.thermoresistible__bu EAALYFAGDRSRYVTGTVLPIDGGTVAGKVIARKSHAE----
Mflv_2415|M.gilvum_PYR-GCK EAALYLATDRSRYVTGTVLPIDGGTVAGKVIVRKPKDQQ---
MMAR_4765|M.marinum_M EAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MUL_0336|M.ulcerans_Agy99 EAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MAV_0886|M.avium_104 EAALYFATERSRYVTGTVLPVDGGTSAGKAMRSKRQG-----
Mvan_0169|M.vanbaalenii_PYR-1 AAAAYLGSEDARYVTGVVLPVDGGMTAGNPRNPLRDLMIAAH
MAB_4680c|M.abscessus_ATCC_199 GAVAYLLSDAASYVTGAELAVDGGWTAGPTLTTITGQ-----
MLBr_01807|M.leprae_Br4923 GAVSFLASEDAGYISGAVIPVDGGLGMGH-------------
.. :: : : *::*. : : **