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SELAGRVAVVTGGASGLGEGLVRRFVAEGAQVMIGDVDKDRGTALAEELGAHTEFLTTDVADQEQVAALV SAGVERFGGLHVMVNNAGVSGTMHRRFLDDDLADFHKVMGVNVLGVMAGTREAARYMADNGGGSILNLTS IGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHHEIRVNAIAPGNIRTAIVAKSASEEDRQRIEEFEANI RAQMRADRPLKREGTVEDVAEAALYFATDRSRYVTGTVLPIDGGTVAGKVIVRKEKR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4859 | - | - | 100% (268) | oxidoreductase, short chain dehydrogenase/reductase family protein |
| M. smegmatis MC2 155 | MSMEG_2206 | fabG | 2e-45 | 42.13% (254) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_3515 | - | 6e-41 | 39.38% (259) | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 2e-44 | 42.58% (256) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2415 | - | 1e-102 | 70.37% (270) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1350 | fabG | 2e-44 | 42.58% (256) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 5e-25 | 30.04% (253) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4680c | - | 1e-36 | 37.07% (259) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4765 | - | 1e-110 | 75.00% (264) | short chain dehydrogenase |
| M. avium 104 | MAV_0886 | - | 1e-107 | 73.03% (267) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3420 | - | 1e-116 | 80.23% (263) | PUTATIVE oxidoreductase, short chain dehydrogenase/reductase |
| M. ulcerans Agy99 | MUL_0336 | - | 1e-109 | 74.24% (264) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4237 | - | 1e-102 | 69.78% (268) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1385|M.bovis_AF2122/97 --------------MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVL
Rv1350|M.tuberculosis_H37Rv --------------MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVL
MSMEG_4859|M.smegmatis_MC2_155 ---------------MSELAGRVAVVTGGASGLGEGLVRRFVAEGAQVMI
TH_3420|M.thermoresistible__bu -----------VTERAGELAGKVAVVTGGAAGLGAGLARRFVAEGAKVLI
MMAR_4765|M.marinum_M --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MUL_0336|M.ulcerans_Agy99 --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MAV_0886|M.avium_104 --------------MVNELAGKVAIVTGGASGIGRGIVERFVAEGARVVI
Mflv_2415|M.gilvum_PYR-GCK ---------------MTELAGKVAVVTGGASGIGRGIAARFAAEGAAVVI
Mvan_4237|M.vanbaalenii_PYR-1 ---------------MTELVGKVAIVTGGASGIGRGIAERFAAEGARVVI
MAB_4680c|M.abscessus_ATCC_199 -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .: ::*** *:* . :: ::* * :
Mb1385|M.bovis_AF2122/97 GDVNLEATEVAAKRLG-GDDVALAVRCDVTQADDVDILIRTAVERFGGLD
Rv1350|M.tuberculosis_H37Rv GDVNLEATEVAAKRLG-GDDVALAVRCDVTQADDVDILIRTAVERFGGLD
MSMEG_4859|M.smegmatis_MC2_155 GDVDKDRGTALAEEL---GAHTEFLTTDVADQEQVAALVSAGVERFGGLH
TH_3420|M.thermoresistible__bu GDVDTGNGAKLAAEL---GADAEFVEADVADLDQVSGLVSTAVERFGGLH
MMAR_4765|M.marinum_M ADVEEERGESLAAAL---GADAMFCRTDVSQPEQVAAVVAAAVENFGGLH
MUL_0336|M.ulcerans_Agy99 ADVEEERGESLAAAL---GADAMFCRTDVSQPEQVAAVVAAAVDNFGGLH
MAV_0886|M.avium_104 ADIETERGERLAAEL---GGEAVFRRTDVSDIEQVGALVAAAVEKFGGLH
Mflv_2415|M.gilvum_PYR-GCK ADVRDDLGEALVRELNESGAKTVYRHTDVGDQAQVADLVSSTVETFGALN
Mvan_4237|M.vanbaalenii_PYR-1 ADVRDDLGEPLAAELNSRGAKTVYRHTDVGDQRQVAELVAAAVDTFGGLD
MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGRQLAAEL---GDAARFTHLDVTDAEQWRELIDTTLAGFGTIT
MLBr_01807|M.leprae_Br4923 THRASVVP-----------DWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
. ** : . : * :
Mb1385|M.bovis_AF2122/97 VMVNNAGITRDATMRTMTE--EQFDQVIAVHLKGTWNGTRLAAAIMRERK
Rv1350|M.tuberculosis_H37Rv VMVNNAGITRDATMRTMTE--EQFDQVIAVHLKGTWNGTRLAAAIMRERK
MSMEG_4859|M.smegmatis_MC2_155 VMVNNAGVSGTMHRRFLDDDLADFHKVMGVNVLGVMAGTREAARYMADNG
TH_3420|M.thermoresistible__bu VMVNNAGISGTMHRSLLDDDLADFDRVMRINVRAVMAGTRDAARHMAEHG
MMAR_4765|M.marinum_M VMVNNAGVSGVMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHG
MUL_0336|M.ulcerans_Agy99 VMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHG
MAV_0886|M.avium_104 VMVNNAGISSPLRR-LLDDDLADFHRVMGVNVLGVMAGTRDAARHMADNG
Mflv_2415|M.gilvum_PYR-GCK VMVNNAGISSPLRKGLFHEDLEEFDRVMRVNLLGVMAGTRDAARHMADHG
Mvan_4237|M.vanbaalenii_PYR-1 VMVNNAGISSPLRKGLFHEDLEEFDRVMRVNLLGVMAGTRDAGRYMADHG
MAB_4680c|M.abscessus_ATCC_199 GLVNNAGISS--AAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHG
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSE--EQFQKVIDVNLTGVFRVAKLASRNMIKQR
:* ***:: : .* :*: ::: .. : . * .
Mb1385|M.bovis_AF2122/97 RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
Rv1350|M.tuberculosis_H37Rv RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
MSMEG_4859|M.smegmatis_MC2_155 GGSILNLTSIGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHHEIRVNAI
TH_3420|M.thermoresistible__bu GGSIINLTSIGGIQAGGGVQTYRASKAAVIQFTKSAAIELAHHEIRVNAL
MMAR_4765|M.marinum_M GGSIVNLTSIGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHYEIRVNAI
MUL_0336|M.ulcerans_Agy99 GGSIVNLTSIGGIQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRVNAI
MAV_0886|M.avium_104 GGAIINLTSIGGIQAGGGVMTYRASKAAVIQFTKAAAIELARYDIRVNAI
Mflv_2415|M.gilvum_PYR-GCK GGSVINLGSIGGIQAGGGVSTYRASKAAIIHFTKCAAIELAHYEVRVNCL
Mvan_4237|M.vanbaalenii_PYR-1 GGSIINLGSIGGIQAGGGVSTYRASKAAIIHFTKCAAIELAHYEVRVNCL
MAB_4680c|M.abscessus_ATCC_199 CGSIVNISSAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNSV
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
* : : * * . * *:* .: ::: * **. : .* :
Mb1385|M.bovis_AF2122/97 APGLIRSAMT------------EAMPQRIWDQKLAEVPMGRAGEPSEVAS
Rv1350|M.tuberculosis_H37Rv APGLIRSAMT------------EAMPQRIWDQKLAEVPMGRAGEPSEVAS
MSMEG_4859|M.smegmatis_MC2_155 APGNIRTAIVAKSASEEDRQRIEEFEANIRAQMRADRPLKREGTVEDVAE
TH_3420|M.thermoresistible__bu APGNIRTAIVRKSATGADLERLERFEARIRQQMRDDRPLKREGTVEDVAE
MMAR_4765|M.marinum_M APGNIPTPLLASSAAGMDQEQVERFTAQIRQTMREDRPLKREGTPEDIAE
MUL_0336|M.ulcerans_Agy99 APGNIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKREGTPEDIAE
MAV_0886|M.avium_104 APGNIPTPILGKSAGDMDPEQRERFEARIREGMREDRPLKREGTPDDVAE
Mflv_2415|M.gilvum_PYR-GCK APGNIPTPILASSATDEDRERLEKFEARIRQQMRDDRPLKREGTADDVAE
Mvan_4237|M.vanbaalenii_PYR-1 APGNIPTPILASSATDEDRERLERFEARIRRQMRDDRPLKREGTAEDVAE
MAB_4680c|M.abscessus_ATCC_199 HPGVIYTPMTAK----------EGFRE--GEGNMPIAAMGRVGNADEVAG
MLBr_01807|M.leprae_Br4923 APGFIDTEMTR------------AMDSKYQEAALQAIPLGRIGAVEEIAG
** * : : : .: * * .::*
Mb1385|M.bovis_AF2122/97 VAVFLASDLSSYMTGTVLDVTG----GRFI-----------
Rv1350|M.tuberculosis_H37Rv VAVFLASDLSSYMTGTVLDVTG----GRFI-----------
MSMEG_4859|M.smegmatis_MC2_155 AALYFATDRSRYVTGTVLPIDGGTVAGKVIVRKEKR-----
TH_3420|M.thermoresistible__bu AALYFAGDRSRYVTGTVLPIDGGTVAGKVIARKSHAE----
MMAR_4765|M.marinum_M AALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MUL_0336|M.ulcerans_Agy99 AALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MAV_0886|M.avium_104 AALYFATERSRYVTGTVLPVDGGTSAGKAMRSKRQG-----
Mflv_2415|M.gilvum_PYR-GCK AALYLATDRSRYVTGTVLPIDGGTVAGKVIVRKPKDQQ---
Mvan_4237|M.vanbaalenii_PYR-1 AALYLATDRSRYITGTVLPVDGGTVAGKVIVRKPPPAEAAT
MAB_4680c|M.abscessus_ATCC_199 AVAYLLSDAASYVTGAELAVDGGWTAGPTLTTITGQ-----
MLBr_01807|M.leprae_Br4923 AVSFLASEDAGYISGAVIPVDGGLGMGH-------------
.. :: : : *::*: : : * *