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PGADQNGRIDATEGRDDGLQVLRRAAAALDEIATAPGRLRLVDVGTNLGLAKSTARRLLVALVDVGFAAV DDSGRYHLGDRLLGLTSADGSTLAARLRPVIERLALATGETVDLSVLRGRQMWFVDQIESAHRLRAVSAV GGRFPLHDTANGKAALALMEDDAIPDGLLDEIAEVRRTGIAYDRDEHTAGISAAGIAVRLPGGHVVAISV PAPTERFRAQESTIVDALRAAAADPVWAGGVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0155 | - | - | 100% (243) | regulatory proteins, IclR |
| M. vanbaalenii PYR-1 | Mvan_0462 | - | 2e-19 | 32.43% (222) | regulatory proteins, IclR |
| M. vanbaalenii PYR-1 | Mvan_2889 | - | 4e-17 | 31.03% (232) | regulatory proteins, IclR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1802c | - | 4e-75 | 63.60% (239) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4551 | - | 9e-20 | 33.96% (212) | regulatory protein, IclR |
| M. tuberculosis H37Rv | Rv1773c | - | 5e-75 | 63.60% (239) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4493 | - | 2e-23 | 31.00% (229) | IclR family transcriptional regulator |
| M. marinum M | MMAR_4423 | - | 2e-14 | 29.22% (243) | transcriptional regulatory protein |
| M. avium 104 | MAV_3024 | - | 3e-18 | 33.95% (215) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_2483 | - | 2e-25 | 34.51% (226) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_3251 | - | 1e-20 | 34.91% (232) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_1967 | - | 6e-14 | 31.58% (228) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1802c|M.bovis_AF2122/97 -------MPPTEGK----STTNRDEGIQVLRRAVAALDEIAAEPGHLRLV
Rv1773c|M.tuberculosis_H37Rv -------MPPTEGK----STTNRDEGIQVLRRAVAALDEIAAEPGHLRLV
Mvan_0155|M.vanbaalenii_PYR-1 -------MPGADQNGRIDATEGRDDGLQVLRRAAAALDEIATAPGRLRLV
MAB_4493|M.abscessus_ATCC_1997 --------------------------MSVLTRAAQILDALAESNSGLSVR
MSMEG_2483|M.smegmatis_MC2_155 --------------------------MADIGRSTLVLDALAEASKPLTLS
Mflv_4551|M.gilvum_PYR-GCK ------MTTP------------VETPSAVIDRVSLVLDAFD-GPGRLTLA
MAV_3024|M.avium_104 ------MPAP------------AETPTAVIDRISLVLDAFD-GPGRLTLA
TH_3251|M.thermoresistible__bu MTATLDQPTPNTTVKRTGTERTGETPSAVLDRISLVLDAFD-GPGRLTLA
MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLA-DLGKAGVT
MUL_1967|M.ulcerans_Agy99 --------------------MRQDSGIGVIDKAVGLLRATAKSPCG--LA
: : * :
Mb1802c|M.bovis_AF2122/97 DLCERLGLAKSTTRRLLVGLVEVGLVSVD-SHGRFALGERLLGFG--SVT
Rv1773c|M.tuberculosis_H37Rv DLCERLGLAKSTTRRLLVGLVEVGLVSVD-SHGRFALGERLLGFG--SVT
Mvan_0155|M.vanbaalenii_PYR-1 DVGTNLGLAKSTARRLLVALVDVGFAAVD-DSGRYHLGDRLLGLT--SAD
MAB_4493|M.abscessus_ATCC_1997 ELAEATGLPKSSVHRIVQELTVSQYVMAGGRGGSYQLGPGLLKLG--LNN
MSMEG_2483|M.smegmatis_MC2_155 ELATRTGLPRSTVHRIVQSLERSLYLVRGVDRHGYSLGPGLLKFG--MNA
Mflv_4551|M.gilvum_PYR-GCK QIVRRTGLPRSSAHRMLERLVQLRWLRRT--GRDYELGMRLVELGSLAVH
MAV_3024|M.avium_104 QIVRRTGLPRSSAHRMLERLVQLRWLRRS--GRDYELGMRLVELGSLAVH
TH_3251|M.thermoresistible__bu QVVRRTGLPRSSAHRMLERLVQLRWLRRD--GRDYELGMRLVELGSLAVH
MMAR_4423|M.marinum_M EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG
MUL_1967|M.ulcerans_Agy99 ELCERTGLPRATAYRLAAALEVHRLLGRD-EDGRWGLGPAITELA--AHV
:: *: :::. *: * : ** : :
Mb1802c|M.bovis_AF2122/97 GAHIAAAFRPTVERVARATDGETVDLSVLRGQRMWFVDQIESSYRLRAVS
Rv1773c|M.tuberculosis_H37Rv GAHIAAAFRPTVERVARATDGETVDLSVLRGQRMWFVDQIESSYRLRAVS
Mvan_0155|M.vanbaalenii_PYR-1 GSTLAARLRPVIERLALAT-GETVDLSVLRGRQMWFVDQIESAHRLRAVS
MAB_4493|M.abscessus_ATCC_1997 RRQFVAPMRKAIATVAREV-NENIDLAMLSGGELVIIEQIATVRNLPTVT
MSMEG_2483|M.smegmatis_MC2_155 HLRLLAGNRPLLARLVREV-GENVELAIFSGREVVVVDQLASVNRLHGVT
Mflv_4551|M.gilvum_PYR-GCK QDRVHRAATPLLHDLHRAT-GLVVHLAVLDGSDVVYLDKIGDGMASAIPT
MAV_3024|M.avium_104 QDRLVRAATPLLVELHRAT-GLVVHLAVLDGPDVVYLEKVGDRLNSVIPS
TH_3251|M.thermoresistible__bu QDRLHRAAIPRLHELHAAT-GLVVHLAVLDGSDVVYLEKVGSRLAAAIPT
MMAR_4423|M.marinum_M HSDLVKLSQDACDKLAADL-GETANLAILDENRAVNIVEAVSTAEIALQT
MUL_1967|M.ulcerans_Agy99 DDPLLTAGATVLPRLCETT-GESVQLYRREGTSRVCVAALEPPAGLRDTV
. : . .* :
Mb1802c|M.bovis_AF2122/97 AVGLRFPLNGTANGKAALAALDDADAEAALCRLDPMVAEG-------LRR
Rv1773c|M.tuberculosis_H37Rv AVGLRFPLNGTANGKAALAALDDADAEAALCRLDPMVAEG-------LRR
Mvan_0155|M.vanbaalenii_PYR-1 AVGGRFPLHDTANGKAALALMEDD-----------AIPDG-------LLD
MAB_4493|M.abscessus_ATCC_1997 VVGRTFALHASSIGKALLSQLPPDQVRNMLPADLEVFTTNTITDVTALLR
MSMEG_2483|M.smegmatis_MC2_155 KVGKSFSLHASCIGLALLAHLPDDQVAGLLSPPLQRFTEHTVTDLPAIMG
Mflv_4551|M.gilvum_PYR-GCK RVGGRQPAHCTAVGKAMLAFNDD-----VDVDLQSRMTKYSIGTAAQLAA
MAV_3024|M.avium_104 RVGGRQPAHCTAVGKAILAYRDEA----TDLDLGARPTKYSISSAPQLAA
TH_3251|M.thermoresistible__bu RVGGRRPANCAAVGKAILAYAEDDGVL-SGTGPLPRNTKYSISDPARLRA
MMAR_4423|M.marinum_M WVGQSCPVHATSSGKVLLAGLDADEVRQRVGATLDSFTENTIVTIDALEA
MUL_1967|M.ulcerans_Agy99 PVGARLPMTAGSGAKVLLAHSDP------------ATQQAVLPTAKFTDR
** . . . . *:
Mb1802c|M.bovis_AF2122/97 EIVEIRRTGIAFDRNEHTPGISAAAIARRA-LGDNVIAISVPAPTARFLE
Rv1773c|M.tuberculosis_H37Rv EIVEIRRTGIAFDRNEHTPGISAAAIARRA-LGDNVIAISVPAPTARFLE
Mvan_0155|M.vanbaalenii_PYR-1 EIAEVRRTGIAYDRDEHTAGISAAGIAVRL-PGGHVVAISVPAPTERFRA
MAB_4493|M.abscessus_ATCC_1997 ELDDVRSTGVAFDHEEHDVGISSVAVPLPH-PAAIPQAMAIVAPTPRFAQ
MSMEG_2483|M.smegmatis_MC2_155 RLDEVRRTQIAVDTEEHDVGICAVATAFPG-PTGALQAVAVVMPTARFRA
Mflv_4551|M.gilvum_PYR-GCK ELAKVRAHGVAYEREESLPGFGCVAAAIGR-PGEAVAAVSVCGPMNRMAF
MAV_3024|M.avium_104 ELAKVRAHGVAFEREESLLGFGCVAAPIGG-PGEAAAAVSVCGPLQRMAL
TH_3251|M.thermoresistible__bu ELAKVRAHGVAFDREESLPGIGCVAAPIGD-PGEAVAAISVCGPMNQMAF
MMAR_4423|M.marinum_M QLAATRAAGWASAREELEIGLNAVAAPVYDSTGRVAAALSVSGPAYRLPA
MUL_1967|M.ulcerans_Agy99 VLAEVRRRGWAQSVAEREPGVASVSAPVRDGRGVVVAAISVSGPIDRIGR
: * * * *. ... . *::: * ::
Mb1802c|M.bovis_AF2122/97 KE---------------------QRIIAALRAAADSPDWTR---------
Rv1773c|M.tuberculosis_H37Rv KE---------------------QRIIAALRAAADSPDWTR---------
Mvan_0155|M.vanbaalenii_PYR-1 QE---------------------STIVDALRAAAADPVWAGGVS------
MAB_4493|M.abscessus_ATCC_1997 RK---------------------TKYVAALDSLTKRANST----------
MSMEG_2483|M.smegmatis_MC2_155 KR---------------------ERAVESLQRINPLLAHRN---------
Mflv_4551|M.gilvum_PYR-GCK ER-LAAPVRVTAMGIWRNAEDGPARVTPTLQPLRPLRGGPAARPVAV---
MAV_3024|M.avium_104 DQRLAAPVRMTAMGVWRNVEGGPQRVAPTLQRLRPLPPMRPQHPVPK---
TH_3251|M.thermoresistible__bu DHRLVAPVRMAALGIWRAMEGARQRVVPTLQQVRPLRPGPTAQSLSHSAL
MMAR_4423|M.marinum_M AD----------------FEEVAQQTIAAADAVSRGLGWTDRIS------
MUL_1967|M.ulcerans_Agy99 RP--------------------GARWAADLLAAADELARRL---------
Mb1802c|M.bovis_AF2122/97 --------------------
Rv1773c|M.tuberculosis_H37Rv --------------------
Mvan_0155|M.vanbaalenii_PYR-1 --------------------
MAB_4493|M.abscessus_ATCC_1997 --------------------
MSMEG_2483|M.smegmatis_MC2_155 --------------------
Mflv_4551|M.gilvum_PYR-GCK ------------RNDALQYA
MAV_3024|M.avium_104 ------------PRPALQYA
TH_3251|M.thermoresistible__bu SHPAQSHPARSHRADTRRFA
MMAR_4423|M.marinum_M --------------------
MUL_1967|M.ulcerans_Agy99 --------------------