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M. thermoresistible (build 8) TH_3251 (-)

annotation: putative transcriptional regulator
coordinates: 696324 - 697268
length: 315

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3251--100% (315)putative transcriptional regulator
M. thermoresistible (build 8)TH_2042-2e-1432.73% (220) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. thermoresistible (build 8)TH_3647-6e-0927.03% (222) PUTATIVE putative transcriptional regulator, IclR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1802c-9e-1831.91% (235) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_4551-1e-11075.28% (267) regulatory protein, IclR
M. tuberculosis H37RvRv1773c-9e-1831.91% (235) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0077-1e-10873.11% (264) IclR family transcriptional regulator
M. marinum MMMAR_4423-3e-1631.03% (232) transcriptional regulatory protein
M. avium 104MAV_3024-1e-10877.22% (259) transcriptional regulator, IclR family protein
M. smegmatis MC2 155MSMEG_2890-1e-12676.19% (294) putative transcriptional regulator
M. ulcerans Agy99MUL_1967-8e-1232.50% (200) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2889-1e-12076.41% (284) regulatory proteins, IclR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1802c|M.bovis_AF2122/97           -----------------MPPTEG----------KSTTNRDEGIQVLRRAV
Rv1773c|M.tuberculosis_H37Rv        -----------------MPPTEG----------KSTTNRDEGIQVLRRAV
MSMEG_2890|M.smegmatis_MC2_155      MED-------------LMTITVESPVT------SGKGAAADTPSAVIDRI
Mvan_2889|M.vanbaalenii_PYR-1       MTNRHMPIRSMTFRRIPMTVTIESPAA------PAAKVATETPSAVIDRV
TH_3251|M.thermoresistible__bu      -----------------MTATLDQPTPNTTVKRTGTERTGETPSAVLDRI
Mflv_4551|M.gilvum_PYR-GCK          -----------------------------------MTTPVETPSAVIDRV
MAV_3024|M.avium_104                -----------------------------------MPAPAETPTAVIDRI
MAB_0077|M.abscessus_ATCC_1997      ---------------------------------MTITADSATPSAVIDRV
MUL_1967|M.ulcerans_Agy99           ------------------------------------MRQDSGIGVIDKAV
MMAR_4423|M.marinum_M               -----------------MSSGISSMIMGTGNDGGASESDPAPTVQSVDRA
                                                                                      

Mb1802c|M.bovis_AF2122/97           AALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSV-DSHGR
Rv1773c|M.tuberculosis_H37Rv        AALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSV-DSHGR
MSMEG_2890|M.smegmatis_MC2_155      SLVLDAFDGPGRLTLAQVVRRTGLPRSSAHRMLERLVQLRWLRR-NGR-D
Mvan_2889|M.vanbaalenii_PYR-1       SLVLDAFDGPGRLTLAQIVRRTGLPRSSAHRMLERLVQLRWLRR-SGR-D
TH_3251|M.thermoresistible__bu      SLVLDAFDGPGRLTLAQVVRRTGLPRSSAHRMLERLVQLRWLRR-DGR-D
Mflv_4551|M.gilvum_PYR-GCK          SLVLDAFDGPGRLTLAQIVRRTGLPRSSAHRMLERLVQLRWLRR-TGR-D
MAV_3024|M.avium_104                SLVLDAFDGPGRLTLAQIVRRTGLPRSSAHRMLERLVQLRWLRR-SGR-D
MAB_0077|M.abscessus_ATCC_1997      SLLLDAFDGPGRLTLAQLVRRTGLPRSSVHRMLERLVQLRWLRR-DGR-D
MUL_1967|M.ulcerans_Agy99           GLLRATAKSP--CGLAELCERTGLPRATAYRLAAALEVHRLLGR-DEDGR
MMAR_4423|M.marinum_M               LLVLELLADLGKAGVTEVADELGVHKSTASRLITALEARGYVEQLSDRGK
                                      :           :.::  . *: :::. *:   *     :        

Mb1802c|M.bovis_AF2122/97           FALGERLLGFG--SVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRM
Rv1773c|M.tuberculosis_H37Rv        FALGERLLGFG--SVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRM
MSMEG_2890|M.smegmatis_MC2_155      YELGMRLVELGSLAVHQDRLHKAAIPKLHELHAATG-LVVHLAVLDGPDV
Mvan_2889|M.vanbaalenii_PYR-1       YELGMRLVELGSLAVHQDRLHKAAIPMLHELHAATG-LVVHLAVLDGSDV
TH_3251|M.thermoresistible__bu      YELGMRLVELGSLAVHQDRLHRAAIPRLHELHAATG-LVVHLAVLDGSDV
Mflv_4551|M.gilvum_PYR-GCK          YELGMRLVELGSLAVHQDRVHRAATPLLHDLHRATG-LVVHLAVLDGSDV
MAV_3024|M.avium_104                YELGMRLVELGSLAVHQDRLVRAATPLLVELHRATG-LVVHLAVLDGPDV
MAB_0077|M.abscessus_ATCC_1997      YELGTRLVELGSLAVHQDRLHAAALPMLHELHRATG-LVVHLSILDGADV
MUL_1967|M.ulcerans_Agy99           WGLGPAITELA--AHVDDPLLTAGATVLPRLCETTG-ESVQLYRREGTSR
MMAR_4423|M.marinum_M               YQLGIGVSRLARARSGHSDLVKLSQDACDKLAADLG-ETANLAILDENRA
                                    : **  :  :.        :          :    .   ..*        

Mb1802c|M.bovis_AF2122/97           WFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDD-------ADAE
Rv1773c|M.tuberculosis_H37Rv        WFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDD-------ADAE
MSMEG_2890|M.smegmatis_MC2_155      VFMEKVGNRMAAAIPTRVGGRQPAHCAAVGKAVLAYADDCDVEALTDDVL
Mvan_2889|M.vanbaalenii_PYR-1       VYMEKVGNRMTAAIPTRVGGRQPAHCAAVGKAMLAFAAAEDIQAYDSAQL
TH_3251|M.thermoresistible__bu      VYLEKVGSRLAAAIPTRVGGRRPANCAAVGKAILAYAEDDGVLS-GTGPL
Mflv_4551|M.gilvum_PYR-GCK          VYLDKIGDGMASAIPTRVGGRQPAHCTAVGKAMLAFNDD-----VDVDLQ
MAV_3024|M.avium_104                VYLEKVGDRLNSVIPSRVGGRQPAHCTAVGKAILAYRDEA----TDLDLG
MAB_0077|M.abscessus_ATCC_1997      VYLEKIGAGIGAAVATRIGGRQPAHCTASGKAILAYRAQILD---GCTAL
MUL_1967|M.ulcerans_Agy99           VCVAALEPPAGLRDTVPVGARLPMTAGSGAKVLLAHSDP-----------
MMAR_4423|M.marinum_M               VNIVEAVSTAEIALQTWVGQSCPVHATSSGKVLLAGLDADEVRQRVGATL
                                      :              :*   *    : .*. **               

Mb1802c|M.bovis_AF2122/97           AALCRLDPMVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRA-LGD
Rv1773c|M.tuberculosis_H37Rv        AALCRLDPMVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRA-LGD
MSMEG_2890|M.smegmatis_MC2_155      ARRTKYSITNSGRLRSELAKVRAHGIAFDREESFPGLGCVAAPIGD-PGQ
Mvan_2889|M.vanbaalenii_PYR-1       PRRTKYSISTHAQLRTELQKVRSHGIAFDREESVPGFGCVAAPIGD-PGE
TH_3251|M.thermoresistible__bu      PRNTKYSISDPARLRAELAKVRAHGVAFDREESLPGIGCVAAPIGD-PGE
Mflv_4551|M.gilvum_PYR-GCK          SRMTKYSIGTAAQLAAELAKVRAHGVAYEREESLPGFGCVAAAIGR-PGE
MAV_3024|M.avium_104                ARPTKYSISSAPQLAAELAKVRAHGVAFEREESLLGFGCVAAPIGG-PGE
MAB_0077|M.abscessus_ATCC_1997      ARKTRYSIGSAAQLRPELDKVRGHGVAFDREELQQGIGCVAAPIGS-IGD
MUL_1967|M.ulcerans_Agy99           -ATQQAVLPTAKFTDRVLAEVRRRGWAQSVAEREPGVASVSAPVRDGRGV
MMAR_4423|M.marinum_M               DSFTENTIVTIDALEAQLAATRAAGWASAREELEIGLNAVAAPVYDSTGR
                                        .            :   *  * *    *   *. ..: .     * 

Mb1802c|M.bovis_AF2122/97           NVIAISVPAPTARFLE-KEQRIIAALRAAAD-------------SPDWTR
Rv1773c|M.tuberculosis_H37Rv        NVIAISVPAPTARFLE-KEQRIIAALRAAAD-------------SPDWTR
MSMEG_2890|M.smegmatis_MC2_155      AVAAVSVCGPMNRMV--FDHRMAAPVRMTALGIWRAMQGAEMRVAPTLQQ
Mvan_2889|M.vanbaalenii_PYR-1       AAAAVSVCGPMNAMK--FDQRLVAPVRMAAMRIWRAVEGGPMRVAPTLQQ
TH_3251|M.thermoresistible__bu      AVAAISVCGPMNQMA--FDHRLVAPVRMAALGIWRAMEGARQRVVPTLQQ
Mflv_4551|M.gilvum_PYR-GCK          AVAAVSVCGPMNRMA--FER-LAAPVRVTAMGIWRNAEDGPARVTPTLQP
MAV_3024|M.avium_104                AAAAVSVCGPLQRMA--LDQRLAAPVRMTAMGVWRNVEGGPQRVAPTLQR
MAB_0077|M.abscessus_ATCC_1997      AVAAVSVCGPMTRMT--FDQRLAAPVRMTAMGIWRNVENGPSRVAPTLQP
MUL_1967|M.ulcerans_Agy99           VVAAISVSGPIDRIGRRPGARWAADLLAAADELARRL-------------
MMAR_4423|M.marinum_M               VAAALSVSGPAYRLPAADFEEVAQQTIAAADAVSRGLGWTDRIS------
                                     . *:** .*   :              :*                    

Mb1802c|M.bovis_AF2122/97           --------------------------------------
Rv1773c|M.tuberculosis_H37Rv        --------------------------------------
MSMEG_2890|M.smegmatis_MC2_155      MRPLRGGPSGTPAGHPAANLALA---------------
Mvan_2889|M.vanbaalenii_PYR-1       VRPLRGG------------MQLA---------------
TH_3251|M.thermoresistible__bu      VRPLRPGPTAQSLSHSALSHPAQSHPARSHRADTRRFA
Mflv_4551|M.gilvum_PYR-GCK          LRPLRGGPAARPVAVRNDALQYA---------------
MAV_3024|M.avium_104                LRPLPPMRPQHPVPKPRPALQYA---------------
MAB_0077|M.abscessus_ATCC_1997      IRPLRCGPAASSTGREMNSPALQYA-------------
MUL_1967|M.ulcerans_Agy99           --------------------------------------
MMAR_4423|M.marinum_M               --------------------------------------