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MSVLTRAAQILDALAESNSGLSVRELAEATGLPKSSVHRIVQELTVSQYVMAGGRGGSYQLGPGLLKLGL NNRRQFVAPMRKAIATVAREVNENIDLAMLSGGELVIIEQIATVRNLPTVTVVGRTFALHASSIGKALLS QLPPDQVRNMLPADLEVFTTNTITDVTALLRELDDVRSTGVAFDHEEHDVGISSVAVPLPHPAAIPQAMA IVAPTPRFAQRKTKYVAALDSLTKRANST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4493 | - | - | 100% (239) | IclR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0077 | - | 1e-17 | 31.11% (225) | IclR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3295 | - | 7e-16 | 26.56% (241) | IclR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1748 | - | 1e-34 | 34.93% (229) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3174 | - | 4e-23 | 29.17% (216) | regulatory protein, IclR |
| M. tuberculosis H37Rv | Rv1719 | - | 1e-34 | 34.93% (229) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4423 | - | 4e-22 | 29.96% (237) | transcriptional regulatory protein |
| M. avium 104 | MAV_3024 | - | 2e-18 | 28.96% (221) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_2483 | - | 2e-55 | 48.02% (227) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_3251 | - | 6e-18 | 30.18% (222) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0155 | - | 2e-23 | 31.00% (229) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4493|M.abscessus_ATCC_1997 --------------------------MSVLTRAAQILDALAESNSGLSVR
MSMEG_2483|M.smegmatis_MC2_155 --------------------------MADIGRSTLVLDALAEASKPLTLS
Mb1748|M.bovis_AF2122/97 -------MSAEEQ-------DTRSGGIQVIARAAELLRVLQAHPGGLSQA
Rv1719|M.tuberculosis_H37Rv -------MSAEEQ-------DTRSGGIQVIARAAELLRVLQAHPGGLSQA
Mvan_0155|M.vanbaalenii_PYR-1 -------MPGADQNGRIDATEGRDDGLQVLRRAAAALDEIATAPGRLRLV
MAV_3024|M.avium_104 ------MPAP------------AETPTAVIDRISLVLDAFD-GPGRLTLA
TH_3251|M.thermoresistible__bu MTATLDQPTPNTTVKRTGTERTGETPSAVLDRISLVLDAFD-GPGRLTLA
Mflv_3174|M.gilvum_PYR-GCK --------MESSSVVGSGRMAERSGGVQSVERAFELMELIGRAGGECSLT
MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLA-DLGKAGVT
: * : :
MAB_4493|M.abscessus_ATCC_1997 ELAEATGLPKSSVHRIVQELTVSQYVMAGGRGGSYQLGPGLLKLGLNNR-
MSMEG_2483|M.smegmatis_MC2_155 ELATRTGLPRSTVHRIVQSLERSLYLVRGVDRHGYSLGPGLLKFGMNAH-
Mb1748|M.bovis_AF2122/97 EIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATTVR-
Rv1719|M.tuberculosis_H37Rv EIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATTVR-
Mvan_0155|M.vanbaalenii_PYR-1 DVGTNLGLAKSTARRLLVALVDVGFAAVDDS-GRYHLGDRLLGLTSADG-
MAV_3024|M.avium_104 QIVRRTGLPRSSAHRMLERLVQLRWLRRSGRDYELGMRLVELGSLAVHQ-
TH_3251|M.thermoresistible__bu QVVRRTGLPRSSAHRMLERLVQLRWLRRDGRDYELGMRLVELGSLAVHQ-
Mflv_3174|M.gilvum_PYR-GCK ELSAESPLPPPTIHRLLRTLVGLGYVR-QLPNRRYALGPRLIRLGEVAN-
MMAR_4423|M.marinum_M EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG
:: : .: *:: * :
MAB_4493|M.abscessus_ATCC_1997 -RQFVAPMRKAIATVAREVNENIDLAMLSGGELVIIEQIATVRNLPTVTV
MSMEG_2483|M.smegmatis_MC2_155 -LRLLAGNRPLLARLVREVGENVELAIFSGREVVVVDQLASVNRLHGVTK
Mb1748|M.bovis_AF2122/97 -LGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSA
Rv1719|M.tuberculosis_H37Rv -LGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSA
Mvan_0155|M.vanbaalenii_PYR-1 -STLAARLRPVIERLALATGETVDLSVLRGRQMWFVDQIESAHRLRAVSA
MAV_3024|M.avium_104 -DRLVRAATPLLVELHRATGLVVHLAVLDGPDVVYLEKVGDRLNSVIPSR
TH_3251|M.thermoresistible__bu -DRLHRAAIPRLHELHAATGLVVHLAVLDGSDVVYLEKVGSRLAAAIPTR
Mflv_3174|M.gilvum_PYR-GCK -RQLGAVAGPVLQSLADDLSETASLAVLDGDMVIYTGQVLSAHMMRTNNE
MMAR_4423|M.marinum_M HSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVSTAEIALQTW
. : . *::: : .
MAB_4493|M.abscessus_ATCC_1997 VGRTFALHASSIGKALLSQLPPDQVRNMLPAD-LEVFTTNTITDVTALLR
MSMEG_2483|M.smegmatis_MC2_155 VGKSFSLHASCIGLALLAHLPDDQVAGLLSPP-LQRFTEHTVTDLPAIMG
Mb1748|M.bovis_AF2122/97 VGESFPLYCCANGKALLAALPPERQARALPSR-LAPLTANTITDRAALRD
Rv1719|M.tuberculosis_H37Rv VGESFPLYCCANGKALLAALPPERQARALPSR-LAPLTANTITDRAALRD
Mvan_0155|M.vanbaalenii_PYR-1 VGGRFPLHDTANGKAALALMEDD----AIP---------------DGLLD
MAV_3024|M.avium_104 VGGRQPAHCTAVGKAILAYRDEAT-DLDLG----ARPTKYSISSAPQLAA
TH_3251|M.thermoresistible__bu VGGRRPANCAAVGKAILAYAEDDG-VLSGTGP-LPRNTKYSISDPARLRA
Mflv_3174|M.gilvum_PYR-GCK VGKRVGLHTSGVGKAVLAELEDARILKLVTQSGLPAPTENSASTLSAVFA
MMAR_4423|M.marinum_M VGQSCPVHATSSGKVLLAGLDADEVRQRVGAT-LDSFTENTIVTIDALEA
** * . *: :
MAB_4493|M.abscessus_ATCC_1997 ELDDVRSTGVAFDHEEHDVGISSVAVPLPHP-AAIPQAMAIVAPTPRFAQ
MSMEG_2483|M.smegmatis_MC2_155 RLDEVRRTQIAVDTEEHDVGICAVATAFPGP-TGALQAVAVVMPTARFRA
Mb1748|M.bovis_AF2122/97 ELNRIRVDGVAYDREEQTEGICAVGAVLRGV-SVELVAVSVPVPAQRFYG
Rv1719|M.tuberculosis_H37Rv ELNRIRVDGVAYDREEQTEGICAVGAVLRGV-SVELVAVSVPVPAQRFYG
Mvan_0155|M.vanbaalenii_PYR-1 EIAEVRRTGIAYDRDEHTAGISAAGIAVRLP-GGHVVAISVPAPTERFRA
MAV_3024|M.avium_104 ELAKVRAHGVAFEREESLLGFGCVAAPIGGP-GEAAAAVSVCGPLQRMAL
TH_3251|M.thermoresistible__bu ELAKVRAHGVAFDREESLPGIGCVAAPIGDP-GEAVAAISVCGPMNQMAF
Mflv_3174|M.gilvum_PYR-GCK NVERVRAEGYAVDDEEFEIGVRSVAMAVPG--APTPMAIGISGPTARMGK
MMAR_4423|M.marinum_M QLAATRAAGWASAREELEIGLNAVAAPVYDSTGRVAAALSVSGPAYRLPA
.: * * :* *. ... . *:.: * ::
MAB_4493|M.abscessus_ATCC_1997 RKTK-YVAALDSLTKRANST------------------------------
MSMEG_2483|M.smegmatis_MC2_155 KRER-AVESLQRINPLLAHRN-----------------------------
Mb1748|M.bovis_AF2122/97 REAE-LAGALLAWVSKVDAWFNGTEDRK----------------------
Rv1719|M.tuberculosis_H37Rv REAE-LAGALLAWVSKVDAWFNGTEDRK----------------------
Mvan_0155|M.vanbaalenii_PYR-1 QEST-IVDALRAAAADP-VWAGGVS-------------------------
MAV_3024|M.avium_104 DQRL-AAPVRMTAMGVWRNVEGGPQRVAPTLQRLRPLPPMRPQHPVPK--
TH_3251|M.thermoresistible__bu DHRL-VAPVRMAALGIWRAMEGARQRVVPTLQQVRPLRPGPTAQSLSHSA
Mflv_3174|M.gilvum_PYR-GCK DLIARAVPALKKATGVISEALIGAKEA-----------------------
MMAR_4423|M.marinum_M ADFEEVAQQTIAAADAVSRGLGWTDRIS----------------------
.
MAB_4493|M.abscessus_ATCC_1997 ---------------------
MSMEG_2483|M.smegmatis_MC2_155 ---------------------
Mb1748|M.bovis_AF2122/97 ---------------------
Rv1719|M.tuberculosis_H37Rv ---------------------
Mvan_0155|M.vanbaalenii_PYR-1 ---------------------
MAV_3024|M.avium_104 -PRPALQYA------------
TH_3251|M.thermoresistible__bu LSHPAQSHPARSHRADTRRFA
Mflv_3174|M.gilvum_PYR-GCK ---------------------
MMAR_4423|M.marinum_M ---------------------