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MPAPAETPTAVIDRISLVLDAFDGPGRLTLAQIVRRTGLPRSSAHRMLERLVQLRWLRRSGRDYELGMRL VELGSLAVHQDRLVRAATPLLVELHRATGLVVHLAVLDGPDVVYLEKVGDRLNSVIPSRVGGRQPAHCTA VGKAILAYRDEATDLDLGARPTKYSISSAPQLAAELAKVRAHGVAFEREESLLGFGCVAAPIGGPGEAAA AVSVCGPLQRMALDQRLAAPVRMTAMGVWRNVEGGPQRVAPTLQRLRPLPPMRPQHPVPKPRPALQYA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3024 | - | - | 100% (278) | transcriptional regulator, IclR family protein |
| M. avium 104 | MAV_3513 | - | 2e-16 | 30.70% (228) | transcriptional regulator, IclR family protein |
| M. avium 104 | MAV_3839 | - | 6e-12 | 34.17% (199) | transcriptional regulator, IclR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1802c | - | 6e-16 | 31.78% (214) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4551 | - | 1e-118 | 78.42% (278) | regulatory protein, IclR |
| M. tuberculosis H37Rv | Rv1773c | - | 6e-16 | 31.78% (214) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0077 | - | 1e-107 | 71.68% (279) | IclR family transcriptional regulator |
| M. marinum M | MMAR_4423 | - | 4e-15 | 30.67% (225) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2890 | - | 1e-111 | 75.86% (261) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3251 | - | 1e-108 | 77.22% (259) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_1967 | - | 2e-11 | 33.33% (198) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2889 | - | 1e-109 | 77.52% (258) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1802c|M.bovis_AF2122/97 -----------------MPPTEG----------KSTTNRDEGIQVLRRAV
Rv1773c|M.tuberculosis_H37Rv -----------------MPPTEG----------KSTTNRDEGIQVLRRAV
MAV_3024|M.avium_104 -----------------------------------MPAPAETPTAVIDRI
Mflv_4551|M.gilvum_PYR-GCK -----------------------------------MTTPVETPSAVIDRV
MSMEG_2890|M.smegmatis_MC2_155 MED-------------LMTITVESPVT------SGKGAAADTPSAVIDRI
Mvan_2889|M.vanbaalenii_PYR-1 MTNRHMPIRSMTFRRIPMTVTIESPAA------PAAKVATETPSAVIDRV
TH_3251|M.thermoresistible__bu -----------------MTATLDQPTPNTTVKRTGTERTGETPSAVLDRI
MAB_0077|M.abscessus_ATCC_1997 ---------------------------------MTITADSATPSAVIDRV
MUL_1967|M.ulcerans_Agy99 ------------------------------------MRQDSGIGVIDKAV
MMAR_4423|M.marinum_M -----------------MSSGISSMIMGTGNDGGASESDPAPTVQSVDRA
Mb1802c|M.bovis_AF2122/97 AALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSV-DSHGR
Rv1773c|M.tuberculosis_H37Rv AALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSV-DSHGR
MAV_3024|M.avium_104 SLVLDAFDGPGRLTLAQIVRRTGLPRSSAHRMLERLVQLRWLRR-SGR-D
Mflv_4551|M.gilvum_PYR-GCK SLVLDAFDGPGRLTLAQIVRRTGLPRSSAHRMLERLVQLRWLRR-TGR-D
MSMEG_2890|M.smegmatis_MC2_155 SLVLDAFDGPGRLTLAQVVRRTGLPRSSAHRMLERLVQLRWLRR-NGR-D
Mvan_2889|M.vanbaalenii_PYR-1 SLVLDAFDGPGRLTLAQIVRRTGLPRSSAHRMLERLVQLRWLRR-SGR-D
TH_3251|M.thermoresistible__bu SLVLDAFDGPGRLTLAQVVRRTGLPRSSAHRMLERLVQLRWLRR-DGR-D
MAB_0077|M.abscessus_ATCC_1997 SLLLDAFDGPGRLTLAQLVRRTGLPRSSVHRMLERLVQLRWLRR-DGR-D
MUL_1967|M.ulcerans_Agy99 GLLRATAKSP--CGLAELCERTGLPRATAYRLAAALEVHRLLGR-DEDGR
MMAR_4423|M.marinum_M LLVLELLADLGKAGVTEVADELGVHKSTASRLITALEARGYVEQLSDRGK
: :.:: . *: :::. *: * :
Mb1802c|M.bovis_AF2122/97 FALGERLLGFG--SVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRM
Rv1773c|M.tuberculosis_H37Rv FALGERLLGFG--SVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRM
MAV_3024|M.avium_104 YELGMRLVELGSLAVHQDRLVRAATPLLVELHRATG-LVVHLAVLDGPDV
Mflv_4551|M.gilvum_PYR-GCK YELGMRLVELGSLAVHQDRVHRAATPLLHDLHRATG-LVVHLAVLDGSDV
MSMEG_2890|M.smegmatis_MC2_155 YELGMRLVELGSLAVHQDRLHKAAIPKLHELHAATG-LVVHLAVLDGPDV
Mvan_2889|M.vanbaalenii_PYR-1 YELGMRLVELGSLAVHQDRLHKAAIPMLHELHAATG-LVVHLAVLDGSDV
TH_3251|M.thermoresistible__bu YELGMRLVELGSLAVHQDRLHRAAIPRLHELHAATG-LVVHLAVLDGSDV
MAB_0077|M.abscessus_ATCC_1997 YELGTRLVELGSLAVHQDRLHAAALPMLHELHRATG-LVVHLSILDGADV
MUL_1967|M.ulcerans_Agy99 WGLGPAITELA--AHVDDPLLTAGATVLPRLCETTG-ESVQLYRREGTSR
MMAR_4423|M.marinum_M YQLGIGVSRLARARSGHSDLVKLSQDACDKLAADLG-ETANLAILDENRA
: ** : :. : : . ..*
Mb1802c|M.bovis_AF2122/97 WFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDD-------ADAE
Rv1773c|M.tuberculosis_H37Rv WFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAALDD-------ADAE
MAV_3024|M.avium_104 VYLEKVGDRLNSVIPSRVGGRQPAHCTAVGKAILAYRDEA----TDLDLG
Mflv_4551|M.gilvum_PYR-GCK VYLDKIGDGMASAIPTRVGGRQPAHCTAVGKAMLAFNDD-----VDVDLQ
MSMEG_2890|M.smegmatis_MC2_155 VFMEKVGNRMAAAIPTRVGGRQPAHCAAVGKAVLAYADDCDVEALTDDVL
Mvan_2889|M.vanbaalenii_PYR-1 VYMEKVGNRMTAAIPTRVGGRQPAHCAAVGKAMLAFAAAEDIQAYDSAQL
TH_3251|M.thermoresistible__bu VYLEKVGSRLAAAIPTRVGGRRPANCAAVGKAILAYAEDDGVLS-GTGPL
MAB_0077|M.abscessus_ATCC_1997 VYLEKIGAGIGAAVATRIGGRQPAHCTASGKAILAYRAQILD---GCTAL
MUL_1967|M.ulcerans_Agy99 VCVAALEPPAGLRDTVPVGARLPMTAGSGAKVLLAHSDP-----------
MMAR_4423|M.marinum_M VNIVEAVSTAEIALQTWVGQSCPVHATSSGKVLLAGLDADEVRQRVGATL
: :* * : .*. **
Mb1802c|M.bovis_AF2122/97 AALCRLDPMVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRA-LGD
Rv1773c|M.tuberculosis_H37Rv AALCRLDPMVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRA-LGD
MAV_3024|M.avium_104 ARPTKYSISSAPQLAAELAKVRAHGVAFEREESLLGFGCVAAPIGG-PGE
Mflv_4551|M.gilvum_PYR-GCK SRMTKYSIGTAAQLAAELAKVRAHGVAYEREESLPGFGCVAAAIGR-PGE
MSMEG_2890|M.smegmatis_MC2_155 ARRTKYSITNSGRLRSELAKVRAHGIAFDREESFPGLGCVAAPIGD-PGQ
Mvan_2889|M.vanbaalenii_PYR-1 PRRTKYSISTHAQLRTELQKVRSHGIAFDREESVPGFGCVAAPIGD-PGE
TH_3251|M.thermoresistible__bu PRNTKYSISDPARLRAELAKVRAHGVAFDREESLPGIGCVAAPIGD-PGE
MAB_0077|M.abscessus_ATCC_1997 ARKTRYSIGSAAQLRPELDKVRGHGVAFDREELQQGIGCVAAPIGS-IGD
MUL_1967|M.ulcerans_Agy99 -ATQQAVLPTAKFTDRVLAEVRRRGWAQSVAEREPGVASVSAPVRDGRGV
MMAR_4423|M.marinum_M DSFTENTIVTIDALEAQLAATRAAGWASAREELEIGLNAVAAPVYDSTGR
. : * * * * *. ..: . *
Mb1802c|M.bovis_AF2122/97 NVIAISVPAPTARFLE-KEQRIIAALRAAAD-------------SPDWTR
Rv1773c|M.tuberculosis_H37Rv NVIAISVPAPTARFLE-KEQRIIAALRAAAD-------------SPDWTR
MAV_3024|M.avium_104 AAAAVSVCGPLQRMA--LDQRLAAPVRMTAMGVWRNVEGGPQRVAPTLQR
Mflv_4551|M.gilvum_PYR-GCK AVAAVSVCGPMNRMA--FER-LAAPVRVTAMGIWRNAEDGPARVTPTLQP
MSMEG_2890|M.smegmatis_MC2_155 AVAAVSVCGPMNRMV--FDHRMAAPVRMTALGIWRAMQGAEMRVAPTLQQ
Mvan_2889|M.vanbaalenii_PYR-1 AAAAVSVCGPMNAMK--FDQRLVAPVRMAAMRIWRAVEGGPMRVAPTLQQ
TH_3251|M.thermoresistible__bu AVAAISVCGPMNQMA--FDHRLVAPVRMAALGIWRAMEGARQRVVPTLQQ
MAB_0077|M.abscessus_ATCC_1997 AVAAVSVCGPMTRMT--FDQRLAAPVRMTAMGIWRNVENGPSRVAPTLQP
MUL_1967|M.ulcerans_Agy99 VVAAISVSGPIDRIGRRPGARWAADLLAAADELARRL-------------
MMAR_4423|M.marinum_M VAAALSVSGPAYRLPAADFEEVAQQTIAAADAVSRGLGWTDRIS------
. *:** .* : :*
Mb1802c|M.bovis_AF2122/97 --------------------------------------
Rv1773c|M.tuberculosis_H37Rv --------------------------------------
MAV_3024|M.avium_104 LRPLPPMRPQHPVPKPRPALQYA---------------
Mflv_4551|M.gilvum_PYR-GCK LRPLRGGPAARPVAVRNDALQYA---------------
MSMEG_2890|M.smegmatis_MC2_155 MRPLRGGPSGTPAGHPAANLALA---------------
Mvan_2889|M.vanbaalenii_PYR-1 VRPLRGG------------MQLA---------------
TH_3251|M.thermoresistible__bu VRPLRPGPTAQSLSHSALSHPAQSHPARSHRADTRRFA
MAB_0077|M.abscessus_ATCC_1997 IRPLRCGPAASSTGREMNSPALQYA-------------
MUL_1967|M.ulcerans_Agy99 --------------------------------------
MMAR_4423|M.marinum_M --------------------------------------