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VSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLADLGKAGVTEVADELGVHKSTASRLITALE ARGYVEQLSDRGKYQLGIGVSRLARARSGHSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVS TAEIALQTWVGQSCPVHATSSGKVLLAGLDADEVRQRVGATLDSFTENTIVTIDALEAQLAATRAAGWAS AREELEIGLNAVAAPVYDSTGRVAAALSVSGPAYRLPAADFEEVAQQTIAAADAVSRGLGWTDRIS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4423 | - | - | 100% (276) | transcriptional regulatory protein |
| M. marinum M | MMAR_1725 | - | 5e-17 | 30.58% (242) | transcriptional regulatory protein |
| M. marinum M | MMAR_4779 | - | 3e-08 | 28.08% (203) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1748 | - | 1e-20 | 32.89% (228) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3087 | - | 1e-86 | 62.89% (256) | transcriptional regulator, TrmB |
| M. tuberculosis H37Rv | Rv1719 | - | 1e-20 | 32.89% (228) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4493 | - | 4e-22 | 29.96% (237) | IclR family transcriptional regulator |
| M. avium 104 | MAV_3513 | - | 1e-28 | 35.20% (250) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_6757 | - | 5e-29 | 36.51% (252) | glycerol operon regulatory protein |
| M. thermoresistible (build 8) | TH_3647 | - | 1e-20 | 31.15% (244) | PUTATIVE putative transcriptional regulator, IclR family |
| M. ulcerans Agy99 | MUL_1967 | - | 5e-17 | 30.58% (242) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0462 | - | 1e-29 | 34.92% (252) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLADLG-KAGVT
Mflv_3087|M.gilvum_PYR-GCK --------MAQHDKTSTTSPTDAPAAVQSVDRALQVLEIVAAHG-QAGVT
MSMEG_6757|M.smegmatis_MC2_155 ----------------------MPGTVQSVERAAAILQLLGIEDESLGLV
MAV_3513|M.avium_104 MPAKRARVAGPAAAAPAADALAPQYPIESVDNALKLLLLLGEQP-EIRLS
Mvan_0462|M.vanbaalenii_PYR-1 --MQKPPVAG---MEHDSTGKLPQYPIESVDNALRLILLLGDRS-EIRLT
TH_3647|M.thermoresistible__bu ---VRKRARG--------AIERPTYLLESVDNALRLLQMLRDGG-AVRLT
MUL_1967|M.ulcerans_Agy99 --------------------MRQDSGIGVIDKAVGLLRATAKSP--CGLA
Mb1748|M.bovis_AF2122/97 --------------MSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQA
Rv1719|M.tuberculosis_H37Rv --------------MSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQA
MAB_4493|M.abscessus_ATCC_1997 --------------------------MSVLTRAAQILDALAESNSGLSVR
: : .* ::
MMAR_4423|M.marinum_M EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG
Mflv_3087|M.gilvum_PYR-GCK EIAAELGVHKSTVSRLVAVLEARGYVEQVSERGKYRLGFAIPRLAHVAGG
MSMEG_6757|M.smegmatis_MC2_155 QIAGALGLAKGTAHGLLRTLHGVGFVEQDAS-GRYRLGPDLFHLGSTQLD
MAV_3513|M.avium_104 EATRYLGVASSTAHRLLAMLAYRGFVRQDPVSKAYLPGPSLTGVAFAIFG
Mvan_0462|M.vanbaalenii_PYR-1 DASEYLHVASSTAHRLLSMLQYRGFVRQDPISRAYQPGPSLTNVAFAVHS
TH_3647|M.thermoresistible__bu EAAEELGVAPSTAHRLLAMLVYRGFAVQD-EKRTYLPGPALRAGPAERGW
MUL_1967|M.ulcerans_Agy99 ELCERTGLPRATAYRLAAALEVHRLLGRD-EDGRWGLGPAITELAAHVDD
Mb1748|M.bovis_AF2122/97 EIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATT--V
Rv1719|M.tuberculosis_H37Rv EIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATT--V
MAB_4493|M.abscessus_ATCC_1997 ELAEATGLPKSSVHRIVQELTVSQYVMAGGRGGSYQLGPGLLKLGLN--N
: : .:. : * : * :
MMAR_4423|M.marinum_M HSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVSTAEIALQTW
Mflv_3087|M.gilvum_PYR-GCK QNDLVKLGQAACDMLSAGVGETANLAVLDADRIVNIVEAIGPSEITLRTW
MSMEG_6757|M.smegmatis_MC2_155 LNELKARALNWADALAARTGEAVRVAAFRAGRAVVAHHVFRADATAQVLE
MAV_3513|M.avium_104 RLDIARSAAPIMRALSEQLRETVHVGMLDGASVRFVAAVEGPAAVRVASR
Mvan_0462|M.vanbaalenii_PYR-1 RMDIPRTAAPILRRLADTLQETVHVGTLDGRLVRFIAALESPSAVRVISR
TH_3647|M.thermoresistible__bu TREFTDVCLPHLEALSTVCGETVNLVIRVGTGVRFLTSVESTAMLRVGDR
MUL_1967|M.ulcerans_Agy99 P--LLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP
Mb1748|M.bovis_AF2122/97 RLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSA
Rv1719|M.tuberculosis_H37Rv RLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSA
MAB_4493|M.abscessus_ATCC_1997 RRQFVAPMRKAIATVAREVNENIDLAMLSGGELVIIEQIATVRNLPTVTV
. :. * :
MMAR_4423|M.marinum_M VGQSCPVHATSSGKVLLAGLDADEVRQRVGAT-LDSFTENTIVTIDALEA
Mflv_3087|M.gilvum_PYR-GCK VGQSCPAYATSSGKVLLAGLDPAELPARIRPP-LTEFTDSTLCGLAELQD
MSMEG_6757|M.smegmatis_MC2_155 VGAIVPLHASALGKVLLA---FDPGAARSLGA-LDSLTYRTITNRAQLQH
MAV_3513|M.avium_104 LGRALPAHCTSTGKVMLAQLSAAELRALLPRERLKRITAHSIGSRAALET
Mvan_0462|M.vanbaalenii_PYR-1 LGGTRPAHCTSTGKVLLAGLSDDELDQLYPDPHLEPLTEHSVRTLTELRT
TH_3647|M.thermoresistible__bu RGQVLPAERTAGGRALLAELDDEVVERLYADR--------SAGQRAELLT
MUL_1967|M.ulcerans_Agy99 VGARLPMTAGSGAKVLLAHSDPATQQAVLPTA-------------KFTDR
Mb1748|M.bovis_AF2122/97 VGESFPLYCCANGKALLAALPPERQARALPSR-LAPLTANTITDRAALRD
Rv1719|M.tuberculosis_H37Rv VGESFPLYCCANGKALLAALPPERQARALPSR-LAPLTANTITDRAALRD
MAB_4493|M.abscessus_ATCC_1997 VGRTFALHASSIGKALLSQLPPDQVRNMLPAD-LEVFTTNTITDVTALLR
* . : .:.:*:
MMAR_4423|M.marinum_M QLAATRAAGWASAREELEIGLNAVAAPVYDSTGRVAA--ALSVSGPAYRL
Mflv_3087|M.gilvum_PYR-GCK ELAAVRERGWACVREELEVGLNAVAAPVYDVHAQVIA--ALSVSGPSYRL
MSMEG_6757|M.smegmatis_MC2_155 ELADTRDRGWAASVEEEQPGVASIAAPVRDRGGYVVA--SIGISGDVERL
MAV_3513|M.avium_104 ELAAIRERGYATNREESEEGVASVAVPIPTRAPGLR--LALNAAAPQNRL
Mvan_0462|M.vanbaalenii_PYR-1 QLAEVRKSGFAISNQESEEGVASVAVAVPQGGSGIRLALALNASAPSYRF
TH_3647|M.thermoresistible__bu ELAAVREVGFGLNVEHTEEGVAAFGAVVRNRLGRAVG--AVTVAVPIVRY
MUL_1967|M.ulcerans_Agy99 VLAEVRRRGWAQSVAEREPGVASVSAPVRDGRGVVVA--AISVSGPIDRI
Mb1748|M.bovis_AF2122/97 ELNRIRVDGVAYDREEQTEGICAVGAVLRGVSVELVA---VSVPVPAQRF
Rv1719|M.tuberculosis_H37Rv ELNRIRVDGVAYDREEQTEGICAVGAVLRGVSVELVA---VSVPVPAQRF
MAB_4493|M.abscessus_ATCC_1997 ELDDVRSTGVAFDHEEHDVGISSVAVPLPHPAAIPQA---MAIVAPTPRF
* * * . . *: :... : : *
MMAR_4423|M.marinum_M P---AADFEEVAQQTIAAADAVSRGLGWTDRIS--
Mflv_3087|M.gilvum_PYR-GCK A---VDRFDEVAKQTVAAAEQISRRLGWTTRN---
MSMEG_6757|M.smegmatis_MC2_155 CDHRARPLERLAELVVRAGRSVSREFGHGREL---
MAV_3513|M.avium_104 D---AARYPAVAAALVAAAKEIGDQLG--------
Mvan_0462|M.vanbaalenii_PYR-1 R---PSDVRKACSALKDAAAELARNLG--------
TH_3647|M.thermoresistible__bu Q---RHARGDLVRQLFRTADEISVDLDGRFDSLEP
MUL_1967|M.ulcerans_Agy99 G---RRPGARWAADLLAAADELARRL---------
Mb1748|M.bovis_AF2122/97 Y----GREAELAGALLAWVSKVDAWFNGTEDRK--
Rv1719|M.tuberculosis_H37Rv Y----GREAELAGALLAWVSKVDAWFNGTEDRK--
MAB_4493|M.abscessus_ATCC_1997 A----QRKTKYVAALDSLTKRANST----------