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MSTDLRGRVALVTGAARGMGAAHARRLAAAGATVAVNDREDSDALTALATEIGGLTAPGDVSDPKSCRAL ATHVAATTGRLDVLVANHAYMTMAPLLEHADDDWWKVVDTNLGGTFFLVQSVLPHMRRTGAGRIVVIASE WGVTGWPEATAYAAAKSGLISLVKTLGRELAREHIIVNAVAPGVIDTPQLQVDADAAGVGLDDIHRRYAE AIPLGRIGSADEVAVAVELLSDFDLEAVVGQVISCNGGSTRTRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0045 | - | - | 100% (254) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4185 | - | 6e-34 | 36.84% (247) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4157 | - | 8e-31 | 37.24% (239) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 2e-30 | 35.06% (251) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0798 | - | 1e-122 | 85.43% (254) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 2e-30 | 35.06% (251) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-30 | 35.95% (242) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4680c | - | 4e-30 | 36.29% (248) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4715 | - | 6e-31 | 37.60% (242) | 3-oxoacyl- |
| M. avium 104 | MAV_3962 | - | 1e-32 | 36.84% (247) | NAD-dependent epimerase/dehydratase:Short-chain |
| M. smegmatis MC2 155 | MSMEG_1071 | - | 1e-115 | 82.54% (252) | 3-oxoacyl- |
| M. thermoresistible (build 8) | TH_4266 | - | 1e-31 | 34.94% (249) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0676 | - | 3e-31 | 34.69% (271) | carveol-like dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0045|M.vanbaalenii_PYR-1 --------------MSTDLRGRVALVTGAARGMGAAHARRLAAAGATVAV
Mflv_0798|M.gilvum_PYR-GCK --------------MTTDLRGRVALVTGAAQGMGAAHARRLAKAGATVAV
MSMEG_1071|M.smegmatis_MC2_155 ---------------MTSLAGRVALVTGAAQGMGAAHARRLASAGATVAV
MMAR_4715|M.marinum_M --------------------MKTAVVTGGASGIGLAIARRLRADGIDVAT
MAV_3962|M.avium_104 --------------------MRVAVVTGGASGMGEATCHELGRRGMKIAV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_4680c|M.abscessus_ATCC_199 -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
Mb2882c|M.bovis_AF2122/97 -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
TH_4266|M.thermoresistible__bu ------------VDDRFSMAGRVAVITGGGTGIGRASALVLAEYGADIVL
MUL_0676|M.ulcerans_Agy99 ---------------MGALDGRVALITGGARGQGRAHALALAGKGADIAL
: ::**. * * * : * :.
Mvan_0045|M.vanbaalenii_PYR-1 NDRE------------DSDALTALATEIG----GLTAPGDVSDPKSCRAL
Mflv_0798|M.gilvum_PYR-GCK NDRE------------DSDALAALASEIG----GLTAAGDVSDPAQCRAV
MSMEG_1071|M.smegmatis_MC2_155 NDIR------------AGDALHALAQEIG----GLTAPGDVSDPAVCRQI
MMAR_4715|M.marinum_M LDLK------------TPDGE-------------LAFSADVTNRSQVDAA
MAV_3962|M.avium_104 LDVD------------EHAAQRVTDDLRTGGATALGVGADVTDRAAVEQA
MLBr_01807|M.leprae_Br4923 THRA------------SVVPD-----------WFFGVECDVTDNDAIGAA
MAB_4680c|M.abscessus_ATCC_199 ADVL------------DGDGRQLAAELG---DAARFTHLDVTDAEQWREL
Mb2882c|M.bovis_AF2122/97 GDVD------------VEAGGAAADELS-----GLFVPTDVCDEDAVNGL
Rv2857c|M.tuberculosis_H37Rv GDVD------------VEAGGAAADELS-----GLFVPTDVCDEDAVNGL
TH_4266|M.thermoresistible__bu AGRR------------PEPLKKTAAEIEALGRRALAVPTDVTAPDECRAL
MUL_0676|M.ulcerans_Agy99 ADAPGPMAELTYPLGSEEDLLATAELVGQLGRRCLPMVVDVRDPAQVNTA
**
Mvan_0045|M.vanbaalenii_PYR-1 ATHVAATTGRLDVLVANHAYMT--MAPLLEHADDDWWKVVDTNLGGTFFL
Mflv_0798|M.gilvum_PYR-GCK TARIAETAGRLDILVANHAYMT--MAPLLEHDPDDWWKVVDTNLGGTFFL
MSMEG_1071|M.smegmatis_MC2_155 ADDVAAATGRLDILVANHAYMT--MAPLLDHDEGDWWRVVDTNLGGTFHL
MMAR_4715|M.marinum_M LTAIRQRLGPVTILVNAAGLDG--FKRFSNITFEDWQRVIDVNLNGVFHT
MAV_3962|M.avium_104 FAKVRSELGPVTVLVTSAGMFG--FSPFLDITAESWSRIIDVNLTGTFHC
MLBr_01807|M.leprae_Br4923 FKAVEEHQGPVEVLVANAGITS--DMLIMRMSEEQFQKVIDVNLTGVFRV
MAB_4680c|M.abscessus_ATCC_199 IDTTLAGFGTITGLVNNAGISS--AAMVADEPLEHFRKVIEINLVGVFIG
Mb2882c|M.bovis_AF2122/97 FDGAAETYGRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLC
Rv2857c|M.tuberculosis_H37Rv FDGAAETYGRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLC
TH_4266|M.thermoresistible__bu VDATVGEFGRLDVLVNNAGGGA--TKPLMKWTDDEWHEVLNLNLSSAWYL
MUL_0676|M.ulcerans_Agy99 VERTVRELGSLDIVLANAGIVS--TGRLEEVSDQVWQQLMDTNLTGVFHT
* : . . . : .: : ** ..:
Mvan_0045|M.vanbaalenii_PYR-1 VQSVLPHMRRTGAGRIVVIASEWGVTG-WPEATAYAAAKSGLISLVKTLG
Mflv_0798|M.gilvum_PYR-GCK VQSVLPYMREAGAGRIVVISSEWGVTG-WPGATAYAASKSGLISLVKTLG
MSMEG_1071|M.smegmatis_MC2_155 VQAVLPHMRRLGAGRIVVIASEWGVIG-WPEATAYAAAKSGLISLVKSLG
MMAR_4715|M.marinum_M IQAVLPDMVAAGWGRIVNISSSSTHSG-TPYMTHYVAAKSAVNGLTKALA
MAV_3962|M.avium_104 CQVALPDMVAANWGRIVMISSSSAQRG-SPFAAHYAASKGAVITLTKSLA
MLBr_01807|M.leprae_Br4923 AKLASRNMIKQRFGRYIFMGSVVGLSG-VPGQANYAASKSGLIGMARSLA
MAB_4680c|M.abscessus_ATCC_199 MQAVIPAMRAHGCGSIVNISSAAGLVG-LALTSGYGASKWGVRGLSKVAA
Mb2882c|M.bovis_AF2122/97 CRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELG
Rv2857c|M.tuberculosis_H37Rv CRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELG
TH_4266|M.thermoresistible__bu SRAAAKPMIDQGRGAIVNISSGAGLLA-MPQAPVYAAAKAGLNNLTGSMA
MUL_0676|M.ulcerans_Agy99 LRAAIPVMRQQRFGRIVATSSMGGRMG-IPELAAYNATKWGIIGLIKSVA
: . * * : .* . . * *:* .: : .
Mvan_0045|M.vanbaalenii_PYR-1 RELAREHIIVNAVAPGVIDTPQLQVDADAAGV-GLDDIHRRYAEAIPLGR
Mflv_0798|M.gilvum_PYR-GCK RELAREHIIVNAVAPGVIDTPQLQVDADAAGV-ALEVIHRRYAESIPLGR
MSMEG_1071|M.smegmatis_MC2_155 RELAPEHIIVNAVAPGVTDTPQLQVDADAAGV-DLATIHAQYAEAIPMGR
MMAR_4715|M.marinum_M LEYGPSGITVNAVPPGFIDTPMLRNAAAQG----HLGDIEQNIARTPVRR
MAV_3962|M.avium_104 REYAPHGITVNNIPPSGIETPMQHQGQAAG----YLPSNEQIAANIPLGY
MLBr_01807|M.leprae_Br4923 RELGSRSITANVVAPGFIDTEMTRAMDSK--------YQEAALQAIPLGR
MAB_4680c|M.abscessus_ATCC_199 IELGRERIRVNSVHPGVIYTPMTAKEGFR--------EGEGNMPIAAMGR
Mb2882c|M.bovis_AF2122/97 VQFARQGIRVNALCPGPVNTPLLQELFAKN-----PERAARRMVHVPLGR
Rv2857c|M.tuberculosis_H37Rv VQFARQGIRVNALCPGPVNTPLLQELFAKN-----PERAARRMVHVPLGR
TH_4266|M.thermoresistible__bu AAWTRKGVRVNCIACGAIRTPGLEADAKRQ-----GFDIDMIGQTNGSGR
MUL_0676|M.ulcerans_Agy99 LEVAKEGITANVICPTTTQTPMMQPAGIGDDQEVPDDLVRRMMKANPIPQ
: .* : *
Mvan_0045|M.vanbaalenii_PYR-1 -IGSADEVAVAVELLSDFDLEAVVGQVISCNGGSTRTRA-------
Mflv_0798|M.gilvum_PYR-GCK -IGVGDEVSAAVELLADFDVEAIVGQVISCNGGSMRARA-------
MSMEG_1071|M.smegmatis_MC2_155 -IGSADEIAATVEFLADFELEAVVGQVISSNGGSTRARA-------
MMAR_4715|M.marinum_M -IGKPEDIAAACAFLVSEEAGYITGQILGVNGGRNT----------
MAV_3962|M.avium_104 -LGTGADIAAAVGFLTSDEARYITGQVLGVNGGAVMLTVRIR----
MLBr_01807|M.leprae_Br4923 -IGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH--------
MAB_4680c|M.abscessus_ATCC_199 -VGNADEVAGAVAYLLSDAASYVTGAELAVDGGWTAGPTLTTITGQ
Mb2882c|M.bovis_AF2122/97 -FAEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL----
Rv2857c|M.tuberculosis_H37Rv -FAEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL----
TH_4266|M.thermoresistible__bu -IAEPDEIGYGVLFFASDASSYCSGQTLYMHGGPGPAGV-------
MUL_0676|M.ulcerans_Agy99 PWLQPEDVSRGVVYLVTDPG-VITGSVLEVGLGGSARMH-------
::. : . : *