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MTSLAGRVALVTGAAQGMGAAHARRLASAGATVAVNDIRAGDALHALAQEIGGLTAPGDVSDPAVCRQIA DDVAAATGRLDILVANHAYMTMAPLLDHDEGDWWRVVDTNLGGTFHLVQAVLPHMRRLGAGRIVVIASEW GVIGWPEATAYAAAKSGLISLVKSLGRELAPEHIIVNAVAPGVTDTPQLQVDADAAGVDLATIHAQYAEA IPMGRIGSADEIAATVEFLADFELEAVVGQVISSNGGSTRARA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1071 | - | - | 100% (253) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_6538 | - | 1e-36 | 41.39% (244) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. smegmatis MC2 155 | MSMEG_0294 | fabG | 6e-34 | 37.80% (246) | 3-oxoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 2e-30 | 35.86% (251) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0798 | - | 1e-109 | 78.57% (252) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 2e-30 | 35.86% (251) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-26 | 34.29% (245) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4680c | - | 5e-30 | 35.48% (248) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4715 | - | 1e-31 | 38.59% (241) | 3-oxoacyl- |
| M. avium 104 | MAV_3962 | - | 6e-37 | 39.84% (246) | NAD-dependent epimerase/dehydratase:Short-chain |
| M. thermoresistible (build 8) | TH_3102 | - | 6e-32 | 39.33% (239) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 2e-32 | 38.91% (239) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_0045 | - | 1e-115 | 82.54% (252) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0798|M.gilvum_PYR-GCK ------MTTDLRGR--------VALVTGAAQGMGAAHARRLAKAGATVAV
Mvan_0045|M.vanbaalenii_PYR-1 ------MSTDLRGR--------VALVTGAARGMGAAHARRLAAAGATVAV
MSMEG_1071|M.smegmatis_MC2_155 -------MTSLAGR--------VALVTGAAQGMGAAHARRLASAGATVAV
Mb2882c|M.bovis_AF2122/97 ---MMDLSQRLAGR--------VAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv ---MMDLSQRLAGR--------VAVITGGGSGIGLAAGRRMRAEGATIVV
MAB_4680c|M.abscessus_ATCC_199 ---MNGNSALLQGK--------NVIVTGGARGLGAAFSRHIVSQGGRVVI
MMAR_4715|M.marinum_M ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
TH_3102|M.thermoresistible__bu ----------LK----------NAVVTGGGSGIGQAVAARLRADGYHVAT
MAV_3962|M.avium_104 ----------MR----------VAVVTGGASGMGEATCHELGRRGMKIAV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
::**. *:* * .: * :.
Mflv_0798|M.gilvum_PYR-GCK NDREDSDALAALASEIG----GLTAAGDVSDPAQCRAVTARIAETAGRLD
Mvan_0045|M.vanbaalenii_PYR-1 NDREDSDALTALATEIG----GLTAPGDVSDPKSCRALATHVAATTGRLD
MSMEG_1071|M.smegmatis_MC2_155 NDIRAGDALHALAQEIG----GLTAPGDVSDPAVCRQIADDVAAATGRLD
Mb2882c|M.bovis_AF2122/97 GD-VDVEAGGAAADELS----GLFVPTDVCDEDAVNGLFDGAAETYGRID
Rv2857c|M.tuberculosis_H37Rv GD-VDVEAGGAAADELS----GLFVPTDVCDEDAVNGLFDGAAETYGRID
MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGR-QLAAELGD--AARFTHLDVTDAEQWRELIDTTLAGFGTIT
MMAR_4715|M.marinum_M LDLKTPDGE-------------LAFSADVTNRSQVDAALTAIRQRLGPVT
MUL_0315|M.ulcerans_Agy99 LDLKTPDGG-------------LAFSADVTNRSQVDAALAAIRQRLGPVT
TH_3102|M.thermoresistible__bu IDLKPGDDE-------------FSHAADVTDRAQVDAAFDAIRTQLGPVT
MAV_3962|M.avium_104 LDVDEHAAQRVTDDLRTGGATALGVGADVTDRAAVEQAFAKVRSELGPVT
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFG-----------VECDVTDNDAIGAAFKAVEEHQGPVE
. ** : * :
Mflv_0798|M.gilvum_PYR-GCK ILVANHAYMTMAP--LLEHDPDDWWKVVDTNLGGTFFLVQSVLPYMREAG
Mvan_0045|M.vanbaalenii_PYR-1 VLVANHAYMTMAP--LLEHADDDWWKVVDTNLGGTFFLVQSVLPHMRRTG
MSMEG_1071|M.smegmatis_MC2_155 ILVANHAYMTMAP--LLDHDEGDWWRVVDTNLGGTFHLVQAVLPHMRRLG
Mb2882c|M.bovis_AF2122/97 IAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAG
Rv2857c|M.tuberculosis_H37Rv IAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAG
MAB_4680c|M.abscessus_ATCC_199 GLVNNAGISSAAM--VADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHG
MMAR_4715|M.marinum_M ILVNAAGLDGFKR--FSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
MUL_0315|M.ulcerans_Agy99 ILVNAAGLDGFKR--FSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
TH_3102|M.thermoresistible__bu ILVNAAGLDLFRR--FTDISFEDWERVINVNLHGVFHCIQAVLPDMIEAG
MAV_3962|M.avium_104 VLVTSAGMFGFSP--FLDITAESWSRIIDVNLTGTFHCCQVALPDMVAAN
MLBr_01807|M.leprae_Br4923 VLVANAGITSDML--IMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
. . . : :: : ** ..: : . *
Mflv_0798|M.gilvum_PYR-GCK AGRIVVISSEWGVTG-WPGATAYAASKSGLISLVKTLGRELAREHIIVNA
Mvan_0045|M.vanbaalenii_PYR-1 AGRIVVIASEWGVTG-WPEATAYAAAKSGLISLVKTLGRELAREHIIVNA
MSMEG_1071|M.smegmatis_MC2_155 AGRIVVIASEWGVIG-WPEATAYAAAKSGLISLVKSLGRELAPEHIIVNA
Mb2882c|M.bovis_AF2122/97 KGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNA
Rv2857c|M.tuberculosis_H37Rv KGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNA
MAB_4680c|M.abscessus_ATCC_199 CGSIVNISSAAGLVG-LALTSGYGASKWGVRGLSKVAAIELGRERIRVNS
MMAR_4715|M.marinum_M WGRIVNISSSSTHSG-TPYMTHYVAAKSAVNGLTKALALEYGPSGITVNA
MUL_0315|M.ulcerans_Agy99 WGRIVNISSSSTHSG-TPYMTHYVAAKSAVNGLTKALALEYGPSGITVNA
TH_3102|M.thermoresistible__bu WGRIVNISSSSTHSG-APYMAPYVAAKSGVNGLTKTLALEYGPAGITVNA
MAV_3962|M.avium_104 WGRIVMISSSSAQRG-SPFAAHYAASKGAVITLTKSLAREYAPHGITVNN
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSG-VPGQANYAASKSGLIGMARSLARELGSRSITANV
* : .* * . * *:* .: : : . : . * .*
Mflv_0798|M.gilvum_PYR-GCK VAPGVIDTPQLQVDADAAGVALEVIHRRYAESIPLGRIGVGDEVSAAVEL
Mvan_0045|M.vanbaalenii_PYR-1 VAPGVIDTPQLQVDADAAGVGLDDIHRRYAEAIPLGRIGSADEVAVAVEL
MSMEG_1071|M.smegmatis_MC2_155 VAPGVTDTPQLQVDADAAGVDLATIHAQYAEAIPMGRIGSADEIAATVEF
Mb2882c|M.bovis_AF2122/97 LCPGPVNTPLLQELFAKN----PERAARRMVHVPLGRFAEPDEIAAAVAF
Rv2857c|M.tuberculosis_H37Rv LCPGPVNTPLLQELFAKN----PERAARRMVHVPLGRFAEPDEIAAAVAF
MAB_4680c|M.abscessus_ATCC_199 VHPGVIYTPMTAKEGFRE-------GEGNMPIAAMGRVGNADEVAGAVAY
MMAR_4715|M.marinum_M VPPGFIDTPMLRNAAAQG---HLGDIEQNIARTPVRRIGKPEDIAAACAF
MUL_0315|M.ulcerans_Agy99 VPPGFIDTPMLRNAAAQG---HLGDIEQNIARTPVRRIGKPEDIAAACAF
TH_3102|M.thermoresistible__bu VPPGFIDTPMLRAAAAKG---YLGDIDKTIEATPVRRMGKPEDIAAACAF
MAV_3962|M.avium_104 IPPSGIETPMQHQGQAAG---YLPSNEQIAANIPLGYLGTGADIAAAVGF
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMDSKY-------QEAALQAIPLGRIGAVEEIAGAVSF
: *. * .: .. ::: :
Mflv_0798|M.gilvum_PYR-GCK LADFDVEAIVGQVISCNGGSMRARA-------
Mvan_0045|M.vanbaalenii_PYR-1 LSDFDLEAVVGQVISCNGGSTRTRA-------
MSMEG_1071|M.smegmatis_MC2_155 LADFELEAVVGQVISSNGGSTRARA-------
Mb2882c|M.bovis_AF2122/97 LASDDASFITASTFLVDGGISSAYVTPL----
Rv2857c|M.tuberculosis_H37Rv LASDDASFITASTFLVDGGISSAYVTPL----
MAB_4680c|M.abscessus_ATCC_199 LLSDAASYVTGAELAVDGGWTAGPTLTTITGQ
MMAR_4715|M.marinum_M LVSEEAGYITGQILGVNGGRNT----------
MUL_0315|M.ulcerans_Agy99 LVSEEAGYITGQILGVNGGRNT----------
TH_3102|M.thermoresistible__bu LISEEAGYITGQILGVNGGRNT----------
MAV_3962|M.avium_104 LTSDEARYITGQVLGVNGGAVMLTVRIR----
MLBr_01807|M.leprae_Br4923 LASEDAGYISGAVIPVDGGLGMGH--------
* . : . : :**