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VSHNVTSSAREDPRIGHSRRVILRAALAEFAAHGYTGFRMESVAARAEVGRSTVYRHWPDKGALIADALA GLSRQPDPAHEDSAATARRRAHILLNHLAQALTDSPVSACVPALIHAAANDDAFRDRLHRFSAQRRQRLT ATIAEGVASGEFPPTVDPEIASAALSGAVFYRALMTADAPDTDFVADLLDEVLGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3506 | - | - | 100% (195) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5008 | - | 2e-13 | 30.57% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1535 | - | 3e-13 | 29.41% (170) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1199c | - | 4e-11 | 25.71% (175) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1167c | - | 4e-11 | 25.71% (175) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3462c | - | 1e-14 | 31.67% (180) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2639 | - | 2e-11 | 28.80% (191) | hypothetical protein MMAR_2639 |
| M. avium 104 | MAV_2958 | - | 1e-12 | 30.11% (186) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5190 | - | 2e-14 | 30.68% (176) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3283 | - | 3e-11 | 28.11% (185) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3114 | - | 1e-08 | 28.40% (169) | hypothetical protein MUL_3114 |
| M. vanbaalenii PYR-1 | Mvan_3287 | - | 2e-84 | 78.46% (195) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3506|M.gilvum_PYR-GCK -------------------------MSHNVTSSAREDPRIG-HSRRVILR
Mvan_3287|M.vanbaalenii_PYR-1 -------------------------MSHSETSRPKEDPRIG-HSRRAILR
Mb1199c|M.bovis_AF2122/97 -------------------------MTVSAPAKANPYRRRGEVLERALYD
Rv1167c|M.tuberculosis_H37Rv -------------------------MTVSAPAKANPYRRRGEVLERALYD
MMAR_2639|M.marinum_M MTLSGEPGYSYTGLVSSDNADPPDAGTGAPVPAGRRSDRRPAQTIRKVLE
MUL_3114|M.ulcerans_Agy99 --------------------------------------------------
MAV_2958|M.avium_104 ---------------MPEDASSPVIAGGAPTGPARRSDRRPGQTIRKVLD
MAB_3462c|M.abscessus_ATCC_199 -----------------MNETVGPGEVDTPRRHFGNRHGRSEAAREAVLH
MSMEG_5190|M.smegmatis_MC2_155 -------------------------------MAGERPGGRTAAVRRAVLS
TH_3283|M.thermoresistible__bu ---------------------------MPGSGARSPGRPRDPALDDAIRA
Mflv_3506|M.gilvum_PYR-GCK AALAEFAAHGYTGFRMESVAARAEVGRSTVYRHWPDKGALIADALA-GLS
Mvan_3287|M.vanbaalenii_PYR-1 AALAEFAANGYAGFRMESVAARAGVGRSTVYRHWPDRAALVADALA-GLN
Mb1199c|M.bovis_AF2122/97 ATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALP
Rv1167c|M.tuberculosis_H37Rv ATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALP
MMAR_2639|M.marinum_M AGLDELRATSFANLTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLLR
MUL_3114|M.ulcerans_Agy99 --MDELRATSFANLTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLLR
MAV_2958|M.avium_104 AGLQELRESSYAGLTMRAVATRAGVSPASAYTYFPSKSALVAAVYLRFLR
MAB_3462c|M.abscessus_ATCC_199 AADDLLVARGYAGVTMEGIAKAAGVAKQTVYRWWSSKVDVLMDVFLEDAA
MSMEG_5190|M.smegmatis_MC2_155 AAEDLLIEAGFDGLELTVVAERAGVGKSTVYRRWGTVPALVADLLTDMAE
TH_3283|M.thermoresistible__bu AARDVVVEHGYDATTLALIADRAGVSVPTIYRRWQHKHELIEEAVLHLDT
. .: : :* * .. : * : ::
Mflv_3506|M.gilvum_PYR-GCK RQPDPAHEDSAATARRRAHILLNHLAQALTD-SPVSACVPALIHAAANDD
Mvan_3287|M.vanbaalenii_PYR-1 RQPDPGHGDGADTAGQRAHVLLSHLAQALTD-SPVSACIPALIHAAANDT
Mb1199c|M.bovis_AF2122/97 PVPEPRADRSARENLLAVFTANCEILAGKTA-LPSMEIVSQLLHEPELRA
Rv1167c|M.tuberculosis_H37Rv PVPEPRADRSARENLLAVFTANCEILAGKTA-LPSMEIVSQLLHEPELRA
MMAR_2639|M.marinum_M DLPLHTDVNDTTKTRVSATMRDMAMVVADEP-ELTAACGTALMADDPAVQ
MUL_3114|M.ulcerans_Agy99 DLPLHTDVNDTTKTRVSATMRDMAMVVADEP-ELTAACGTALMADDPAVQ
MAV_2958|M.avium_104 DLPVHTDVNETAQRRVSATLRDMAVVVADEP-ELTAACGAALMADDPAVK
MAB_3462c|M.abscessus_ATCC_199 CQLDPPDLGGLEADLRHHLSATAQFLAADDAGAVFRALIGQSQHDGQLAD
MSMEG_5190|M.smegmatis_MC2_155 QSLPRADTGSLRGDLQANARLVRRTLADARQGRLFKAMIAAATCDPRTAE
TH_3283|M.thermoresistible__bu FELPEP-TGDLEADLGTWVRLFLTVAMEPAARAAVPGLMSAYSRNPDDYR
Mflv_3506|M.gilvum_PYR-GCK AFRDRLHRFSAQRRQRLTATIAEGVASGEFPPTVDPEIASAALSGAVFYR
Mvan_3287|M.vanbaalenii_PYR-1 DFRDRLHGFSAQRRRRLTDVISAGVTAGEFPATVDPETASVALSGGVFYR
Mb1199c|M.bovis_AF2122/97 IFIN---SVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQH
Rv1167c|M.tuberculosis_H37Rv IFIN---SVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQH
MMAR_2639|M.marinum_M PLRA---QIGEEVARRIGAALGPGWPR-SVKSTLQMTFSGALMTARFLSY
MUL_3114|M.ulcerans_Agy99 PLRT---QIGEEVARRIGAALGPGWPR-SVKSTLQMTFSGALMTARFLSY
MAV_2958|M.avium_104 PLRE---QIGEEVSRRIAAALGPGWPR-AVKSTLQMTFSGALMTARFVSF
MAB_3462c|M.abscessus_ATCC_199 DFRG---RYLREQQARDQIPIARAVARGELPADVDVAHVAEQLVAPLYYR
MSMEG_5190|M.smegmatis_MC2_155 ALED----FYARRIAEWSGCVTDAIARGEAPAGTDAAAAIRQVSAPLYYQ
TH_3283|M.thermoresistible__bu RLMT---RGELPVRAAIAAMLERAKAAGQAAPDCDPDAVFELIRGATFLR
: : . . .
Mflv_3506|M.gilvum_PYR-GCK ALMTADAPDTDFVADLLDEVLGR----------
Mvan_3287|M.vanbaalenii_PYR-1 CLMTADAADADFVAGLLDAVLGR----------
Mb1199c|M.bovis_AF2122/97 VLFTGSPPDREQLTRIIDAMILTTGERRES---
Rv1167c|M.tuberculosis_H37Rv VLFTGSPPDREQLTRIIDAMILTTGERRES---
MMAR_2639|M.marinum_M EEIAG--QLDEAVNLILGAAVA-----------
MUL_3114|M.ulcerans_Agy99 EEIAG--QLDEAVNLILGAAVA-----------
MAV_2958|M.avium_104 AEISG--QLDEAVDLILGAARAS----------
MAB_3462c|M.abscessus_ATCC_199 VIVTGETVDAAFVDRIVEDFLRRRE--------
MSMEG_5190|M.smegmatis_MC2_155 FLTSTKRLTTADADRAAEAAVAAIDAGVYTARG
TH_3283|M.thermoresistible__bu ALTHSDEDAEAFCTRITEAVLRAVRS-------