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MQLVFPLPHMLRLPAMSQPWEGSVTGADQTRMAKCADAWGYDMIAVPEHFVIPAEHVELSGPHYLQSTVA QAYLAGATERIRLNSCITVLPLQHPIVLAKALATADWMSGGRMMVTFGVGWLKGEFDALGVPFRERGRIA DEYLAAIVELWTSDSPSFDGRYVSFDEIAFEPKPVQRPHLPIWIGGDADAALRRAAKYASGWWSFLTPPD KIAERVEFIKSQDGYDGRPFDVVHGLGTNRVGEGHVAQKDPHARPGMSAAEIADKLNWLGEQGVTVSAVP IPKVSGVEEYLDYAQWVIEEIRPQVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1590 | - | - | 100% (306) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_4544 | - | 1e-37 | 36.07% (219) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_4097 | - | 2e-36 | 42.35% (196) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 6e-28 | 28.53% (319) | hypothetical protein Mb0815c |
| M. tuberculosis H37Rv | Rv0791c | - | 6e-28 | 28.53% (319) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00131 | - | 1e-11 | 25.74% (237) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 5e-31 | 34.36% (259) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_3440 | - | 8e-36 | 38.24% (204) | hypothetical protein MMAR_3440 |
| M. avium 104 | MAV_3045 | - | 1e-144 | 75.08% (305) | hypothetical protein MAV_3045 |
| M. smegmatis MC2 155 | MSMEG_0654 | - | 1e-155 | 83.93% (305) | hypothetical protein MSMEG_0654 |
| M. thermoresistible (build 8) | TH_2945 | - | 1e-132 | 71.48% (305) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2716 | - | 7e-36 | 38.24% (204) | hypothetical protein MUL_2716 |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 1e-166 | 89.84% (305) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0815c|M.bovis_AF2122/97 MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFL
Rv0791c|M.tuberculosis_H37Rv MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFL
MMAR_3440|M.marinum_M ------------MSAAAAKLSIATP---VVTLLPGVSAPWEKTASIEDLT
MUL_2716|M.ulcerans_Agy99 ------MLASIAMSAAAAKLSIATP---VVTLLPGVSAPWEKTASIEDLT
Mflv_1590|M.gilvum_PYR-GCK -----------------MQLVFPLP---HMLRLPAMSQPWEGSVTGADQT
Mvan_5167|M.vanbaalenii_PYR-1 -----------------MRLVFALP---HMLRLPAMSQPWEASVTGADQT
MSMEG_0654|M.smegmatis_MC2_155 ------------MKEFGMKLVFNLP---HMLRLKAMMQPWEAEVTGADQT
MAV_3045|M.avium_104 -----------------MKFAFPVP---HLMRLKAIAQPWEAAVTGPEQR
TH_2945|M.thermoresistible__bu -----------------MKFTFALP---HMMELDAMMQPWEMAVTGADQT
MAB_0366|M.abscessus_ATCC_1997 -----------------MKIGVVAPVELGVTAEPDKILEFARAAERLGFS
MLBr_00131|M.leprae_Br4923 ------------MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSY
:
Mb0815c|M.bovis_AF2122/97 TISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAALS
Rv0791c|M.tuberculosis_H37Rv TISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAALS
MMAR_3440|M.marinum_M QIA--ETADKLGYYHLTCSEHIALPAAEKRRRGTR---YWDPLATLGYLA
MUL_2716|M.ulcerans_Agy99 QIA--ETADKLGYYHLTCSEHIALPAAEKRRRGTR---YWDPLATLSYLA
Mflv_1590|M.gilvum_PYR-GCK RMA--KCADAWGYDMIAVPEHFVIPAEHVELSGPH---YLQSTVAQAYLA
Mvan_5167|M.vanbaalenii_PYR-1 RMA--RCADQWGYDMIAVPEHFVIPAEHVELSGPH---YLQSTVAQAYLA
MSMEG_0654|M.smegmatis_MC2_155 RMV--KCADRWGYDMIAVPEHFVIPNEHVELSGPH---YLQSTVAQAYIA
MAV_3045|M.avium_104 RMM--QCADRWGYDMIAVPEHLVIPVDQVELSGSH---YLHSTTAQAFIA
TH_2945|M.thermoresistible__bu RMA--RRAEELGFDMIAVPEHIVMPREHVDLSGGH---WLHSTIAQAYFA
MAB_0366|M.abscessus_ATCC_1997 EISVVEHAVVIGDTQSTYPYSPTGQSHLPDDIDIP-----DPLELLSFVA
MLBr_00131|M.leprae_Br4923 WVG--DHLNALVPRSVATPKYLGVAAKVVPKIDAN----YEPWTMLGNLA
: : . . . .:
Mb0815c|M.bovis_AF2122/97 RDTTK--LRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAGWFR
Rv0791c|M.tuberculosis_H37Rv RDTTK--LRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAGWFR
MMAR_3440|M.marinum_M ARTQR--IRLATNVLVLGYHHPLEIAKRYGTLDTVSNGRLILGVGVGSLK
MUL_2716|M.ulcerans_Agy99 ARTQR--IRLATNVLVLGYHHPLEIAKRYGTLDTVSNGRLILGVGVGSLK
Mflv_1590|M.gilvum_PYR-GCK GATER--IRLNSCITVLPLQHPIVLAKALATADWMSGGRMMVTFGVGWLK
Mvan_5167|M.vanbaalenii_PYR-1 GATER--IRLNSCITVLPLQHPVVLAKALATADWMSGGRMMVTFGVGWLQ
MSMEG_0654|M.smegmatis_MC2_155 GATER--IMLNSCITVLPLQHPIVLAKALATADWMSSGRMMVTFGVGWLQ
MAV_3045|M.avium_104 GATER--VAINSCVTILPLQHPIVLAKALATADWMSGGRMMVTFGVGWLA
TH_2945|M.thermoresistible__bu GATER--ITLNSCVTILPLQHPLVTAKALATADWLSGGRMMVTFGVGWLQ
MAB_0366|M.abscessus_ATCC_1997 AATTT--LGLSTGVLVLPDHHPVVLAKRLATLDRLSRGRLRICAGVGWMR
MLBr_00131|M.leprae_Br4923 AGNRLNGLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVGERE
. : : : ::* *: .* . :: *: : *.*
Mb0815c|M.bovis_AF2122/97 RESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPT--YAGRFYTLDGA
Rv0791c|M.tuberculosis_H37Rv RESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPT--YAGRFYTLDGA
MMAR_3440|M.marinum_M EEFDLIGAPFE---DRGARADDALRALRAALSVPEPR--YHGEFYSFRDM
MUL_2716|M.ulcerans_Agy99 EEFDLIGAPFE---NRGARADDALRALRAALSVPEPR--YHGEFYSFRDM
Mflv_1590|M.gilvum_PYR-GCK GEFDALGVPFR---ERGRIADEYLAAIVELWTSDSPS--FDGRYVSFDEI
Mvan_5167|M.vanbaalenii_PYR-1 GEFEALGVPFR---ERGRMADEYLAVIKELWTSDAPS--FEGKYVSFREV
MSMEG_0654|M.smegmatis_MC2_155 REFELLGVPFH---ERGRMADEYLAAIVELWTSDSPK--FEGRYVSFGDI
MAV_3045|M.avium_104 REFELLGVPFG---ERGRIADEYLAAIDELWTSDTPR--FDGRYVSFADI
TH_2945|M.thermoresistible__bu REFELLGVPFR---KRGRIADEYLAAIIELWTQDEPS--FAGQFVSFEDV
MAB_0366|M.abscessus_ATCC_1997 EEIEACGGDFD---RRGRAADEAIAVMRALWSTDGPTS-HDGEFYSFRNA
MLBr_00131|M.leprae_Br4923 GN-EPYGVEWT---KPVARFQEALATIRALWDSNGELVSRESQFFPLHNA
: : * : : : .: ..: .:
Mb0815c|M.bovis_AF2122/97 TCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSP-QQVTQRRG
Rv0791c|M.tuberculosis_H37Rv TCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSP-QQVTQRRG
MMAR_3440|M.marinum_M VVDPCAVQKRLP-IWVGGRTLRSLRRATSLAEGWVPFGIS----LGEARD
MUL_2716|M.ulcerans_Agy99 VVDPCAVQKRLP-IWVGGRTLRSLRRATSLAEGWVPFGIS----LGEARD
Mflv_1590|M.gilvum_PYR-GCK AFEPKPVQRPHLPIWIGGDADAALRRAAKYASGWWSFLTPP-DKIAERVE
Mvan_5167|M.vanbaalenii_PYR-1 AFEPKPVQKPHLPIWIGGDADAALRRAAKYASGWWSFLTPP-EKLAERLD
MSMEG_0654|M.smegmatis_MC2_155 AFEPKPVQKPHLPIFIGGDADAALRRAARYASGWWSFLTPP-EKLAERID
MAV_3045|M.avium_104 AFEPKPVQKPHLPVWIGGDADAALRRAARFGSGWWPFLTPP-EQIAEKLD
TH_2945|M.thermoresistible__bu VFEPKPIQQPHPPIWIGGDSDAALRRAARFASGWFTFLTKP-EDIAARVD
MAB_0366|M.abscessus_ATCC_1997 YSYPKPVRPQGVPLYIGGHSKAAARRAGRLGSGFQPLGLVG-DDLTAAVG
MLBr_00131|M.leprae_Br4923 LFDLPPYRGKWPEIWVAAHGPRMLQATGRYADAWIPIVLVRPTDYSCALE
. : :::.. : : ...
Mb0815c|M.bovis_AF2122/97 FLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEPGLIV
Rv0791c|M.tuberculosis_H37Rv FLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEPGLIV
MMAR_3440|M.marinum_M WLSRFDIGSG--------------------------FEVVLSSPEPLNPI
MUL_2716|M.ulcerans_Agy99 WLSRFDIGSG--------------------------FEVVLSSPEPLNPI
Mflv_1590|M.gilvum_PYR-GCK FIKSQDGYDGRPFDVVHGLGTN------------RVGEGHVAQKDPHARP
Mvan_5167|M.vanbaalenii_PYR-1 FIKSQPDYDGRPFDVVHGLGTN------------RVGEGHVAQHDPDARP
MSMEG_0654|M.smegmatis_MC2_155 FIKSQPEYDGRAFDVVHGMATT------------RVGEGHTVRDDPNARP
MAV_3045|M.avium_104 YIKSQPCYDGRPFEVMHGLGTN------------RVGEGHVARRDVRDRP
TH_2945|M.thermoresistible__bu IITSQPEYDGRPFDVMHGLGTN------------RVGEGHVPTGDRGAWP
MAB_0366|M.abscessus_ATCC_1997 VMRAAAVDAGRDPRGLD------------------LVLGHGLHRVDQAAL
MLBr_00131|M.leprae_Br4923 VVRTAASDAGRDPMSITPAAVRG---IITGRTRDDVDEALDSVLVRMIAL
: *
Mb0815c|M.bovis_AF2122/97 GT-PDRCVER-IREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTE
Rv0791c|M.tuberculosis_H37Rv GT-PDRCVER-IREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTE
MMAR_3440|M.marinum_M GD-PERTRHL-LADLAAHGATTICATFAHSSRQQYLDNL------HALAE
MUL_2716|M.ulcerans_Agy99 GD-PERTRHL-LADLAAHGATTICATFAHSSRQQYLDNL------HALAE
Mflv_1590|M.gilvum_PYR-GCK GMSAAEIADK-LNWLGEQGVTVSAVPIPKVSGVEEYLDYAQWVIEEIRPQ
Mvan_5167|M.vanbaalenii_PYR-1 GMSAAEIVDR-LSWLGAQGVTVSAVPIPKVRGVEEYLDYAQWVIEEIKPQ
MSMEG_0654|M.smegmatis_MC2_155 GMSAQEIIDR-LSWLGEQGVTVSAVPLPPVRGVDEYLDYAQWVIEEIKPQ
MAV_3045|M.avium_104 GMSAGQIVDR-LGWLAEQGVTVTAVPVPAVGGVDEYLDYAQWVIEEIKPQ
TH_2945|M.thermoresistible__bu GMSAAELIDR-IGALHEHGVTYTSVPIPPVRGVEEYLDYSQWVMEEIAPN
MAB_0366|M.abscessus_ATCC_1997 DQAAHAGAGR-MLLSASRRATTLEAVLEEMAGCATRLELGGPR-------
MLBr_00131|M.leprae_Br4923 GVPGEAWARHGVEHPMGADFAGVQDIIPQTIDEETVVSYAAKVPAALMKE
. : .
Mb0815c|M.bovis_AF2122/97 VTIP----------------------------------------------
Rv0791c|M.tuberculosis_H37Rv VTIP----------------------------------------------
MMAR_3440|M.marinum_M LDSP----------------------------------------------
MUL_2716|M.ulcerans_Agy99 LDSP----------------------------------------------
Mflv_1590|M.gilvum_PYR-GCK VR------------------------------------------------
Mvan_5167|M.vanbaalenii_PYR-1 VP------------------------------------------------
MSMEG_0654|M.smegmatis_MC2_155 VP------------------------------------------------
MAV_3045|M.avium_104 LA------------------------------------------------
TH_2945|M.thermoresistible__bu VP------------------------------------------------
MAB_0366|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00131|M.leprae_Br4923 VLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSSLRKTVSALLPHARV
Mb0815c|M.bovis_AF2122/97 -------
Rv0791c|M.tuberculosis_H37Rv -------
MMAR_3440|M.marinum_M -------
MUL_2716|M.ulcerans_Agy99 -------
Mflv_1590|M.gilvum_PYR-GCK -------
Mvan_5167|M.vanbaalenii_PYR-1 -------
MSMEG_0654|M.smegmatis_MC2_155 -------
MAV_3045|M.avium_104 -------
TH_2945|M.thermoresistible__bu -------
MAB_0366|M.abscessus_ATCC_1997 -------
MLBr_00131|M.leprae_Br4923 LRGLKKL