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QFAITHPMHSHPYNPELVTGAGIARVAVAAEKAGFGGFGFTDHPAPTQRWLEAGGHDALDPFVAMGFAAA HTTTLRLIPNIVVLPYRNPFVVAKAGATLDLISDGRFTLAVGVGYLKREFAALGVEFDERAAVFEEALDV ITQIWTTDDLSYDGRNFSAKGITAHPKPLTTPHPPIWVGGNTSAARARVAKYAQGWCPFRAPAMLAQTAR TAALETTEHLAKGIDDLRRRLEDAGRDPADVDITFTNDAGGAPGTDDFNADEFLAGAEELERAGVTWLQV NVPGDSLAHAVEAIEGFGETVIAQR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4097 | - | - | 100% (306) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_1590 | - | 2e-36 | 42.35% (196) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_4839 | - | 4e-31 | 34.73% (262) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 1e-28 | 39.78% (186) | hypothetical protein Mb3106c |
| M. tuberculosis H37Rv | Rv3079c | - | 1e-28 | 39.78% (186) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00131 | - | 1e-13 | 27.73% (238) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 1e-27 | 31.62% (234) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_0393 | - | 1e-127 | 69.64% (303) | hypothetical protein MMAR_0393 |
| M. avium 104 | MAV_5129 | - | 1e-126 | 68.98% (303) | hypothetical protein MAV_5129 |
| M. smegmatis MC2 155 | MSMEG_4820 | - | 1e-129 | 70.16% (305) | hypothetical protein MSMEG_4820 |
| M. thermoresistible (build 8) | TH_2146 | - | 1e-133 | 72.79% (305) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1043 | - | 1e-123 | 69.49% (295) | hypothetical protein MUL_1043 |
| M. vanbaalenii PYR-1 | Mvan_2248 | - | 1e-156 | 84.92% (305) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 -----------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHTHI
Rv3079c|M.tuberculosis_H37Rv -----------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHTHI
Mflv_4097|M.gilvum_PYR-GCK ---MQFAITHPMHSHPYNPELVTGAGIARVAVAAEKAGFGGFGFTDH---
Mvan_2248|M.vanbaalenii_PYR-1 ---MQFAITHPMHSHPYNPELVTGTGIAQVAQAAEKAGFGGFGFTDH---
TH_2146|M.thermoresistible__bu ---MRFAFTYPMDSHPYHPDLATGAAVARVAATAETAGFSGFGFTDH---
MMAR_0393|M.marinum_M ---MRFIITHPMHSHPYHPELASGAGVAAVAAAAERAGFHGFGFTDH---
MUL_1043|M.ulcerans_Agy99 -----------MHSHPYHPELASGAGVAAVAAAAERAGFHGFGFTDH---
MAV_5129|M.avium_104 ---MRFTITHPMHSHPYNRELVSGDAIAKVAAATEAAGIHGFGFTDH---
MSMEG_4820|M.smegmatis_MC2_155 ---MRYSITHPMHSHPYHPDLVSGSGVVAVAAAAEAAGFDGFGFTDH---
MAB_0366|M.abscessus_ATCC_1997 ---MKIGVVAPVELG----VTAEPDKILEFARAAERLGFSEISVVEHAVV
MLBr_00131|M.leprae_Br4923 MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALVPR
: . .
Mb3106c|M.bovis_AF2122/97 PVNTQS---PYPGGGPIPEKYYRTLDPFVALAAAAATTQSLVLGTGIALI
Rv3079c|M.tuberculosis_H37Rv PVNTQS---PYPGGGPIPEKYYRTLDPFVALAAAAATTQSLVLGTGIALI
Mflv_4097|M.gilvum_PYR-GCK PAPTQR---WLEAGG------HDALDPFVAMGFAAAHTTTLRLIPNIVVL
Mvan_2248|M.vanbaalenii_PYR-1 PAPTQR---WLEAGG------HDALDPFVAMGFAAAHTSTLRLIPNIVVL
TH_2146|M.thermoresistible__bu PAPTQK---WLDHGG------HDTLDPFVAMGFAAAHTTTLRLIPHIVVL
MMAR_0393|M.marinum_M PAPSQR---WLEAGG------HDSLDPFVALGFAAAQTTSLRLIPNIVVL
MUL_1043|M.ulcerans_Agy99 PAPSQR---WLEAGG------HDSLDPFVALGFAAAQTTSLRLIPNIVVL
MAV_5129|M.avium_104 PAPSQR---WLEAGG------HDALDPFVALGFAAATTSTLRLIPNIVVL
MSMEG_4820|M.smegmatis_MC2_155 PAPSQR---WLDAGG------HDAVDPFVAMAYAAAQTTTLRLVPNIVVL
MAB_0366|M.abscessus_ATCC_1997 IGDTQSTYPYSPTGQSHLPDDIDIPDPLELLSFVAAATTTLGLSTGVLVL
MLBr_00131|M.leprae_Br4923 SVATPK---YLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVT
: . :* :. ** . * : :
Mb3106c|M.bovis_AF2122/97 PE--RDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGR
Rv3079c|M.tuberculosis_H37Rv PE--RDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGR
Mflv_4097|M.gilvum_PYR-GCK PY--RNPFVVAKAGATLDLISDGRFTLAVGVGYLKREFAALGVEFDERAA
Mvan_2248|M.vanbaalenii_PYR-1 PY--RNPFVVAKAGATLDLISEGRFTLAVGVGYLKREFTALGVDFDERAE
TH_2146|M.thermoresistible__bu PY--RNPFVVAKAGASVDLLSGGRFTLGVGVGYLKREFAALGVDFEERAA
MMAR_0393|M.marinum_M PY--RNPFVVAKSAATLDLLSGGRFILAVGVGYLKREFAALGVDHAERAE
MUL_1043|M.ulcerans_Agy99 PY--RNPFVVAKSAATLDLLSGGRFILAVGVGYLKREFAALGVDHAERAE
MAV_5129|M.avium_104 PY--RNPFVVAKSGATLDLLSGGRFTLAVGVGYLKREFAALGVSYDERAE
MSMEG_4820|M.smegmatis_MC2_155 PY--RNPFVVAKSGATLDLLSGGRFTLAVGVGYLKREFAALGVAFDERTE
MAB_0366|M.abscessus_ATCC_1997 PD--HHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGR
MLBr_00131|M.leprae_Br4923 DAGRRNPAVTAQAAATLHLLTRGKAMLGIGVG-EREGNEPYGVEWTKPVA
:.* * *: *::. :: *: : *** :. *
Mb3106c|M.bovis_AF2122/97 VIDERLRAIIEIWTQE--QAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGG
Rv3079c|M.tuberculosis_H37Rv VIDERLRAIIEIWTQE--QAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGG
Mflv_4097|M.gilvum_PYR-GCK VFEEALDVITQIWTTD--DLSYDGRNFSAKGITAHPKPLTTPHPPIWVGG
Mvan_2248|M.vanbaalenii_PYR-1 LFEESLQVIRDAWTTD--DITFEGKHFSAKGITAHPRPVSTPHPPIWVGG
TH_2146|M.thermoresistible__bu LFEEALEVIRAIWTTD--NVSYTGRHFTADGITAHPHPVTKPHPPIWIGG
MMAR_0393|M.marinum_M LFEEALQVIRAVWTSD--DISFEGRHFSARGITAHPRPASNPYPPIWVGG
MUL_1043|M.ulcerans_Agy99 LFDEALQVIRAVWTSD--DISFEGRHFSARGITAHPRPASNPYPPIWVGG
MAV_5129|M.avium_104 LFEEALQVIRAVWTGD--DISFEGRHFSARGITAHPRPVSSPHPPIWIGG
MSMEG_4820|M.smegmatis_MC2_155 LFDESLEVIRGIWTTD--DFTYEGMHFSARGITAHPRPVNP--PPIWIGG
MAB_0366|M.abscessus_ATCC_1997 AADEAIAVMRALWSTDG-PTSHDGEFYSFRNAYSYPKPVRPQGVPLYIGG
MLBr_00131|M.leprae_Br4923 RFQEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWVAA
:* : .: * : . * :::..
Mb3106c|M.bovis_AF2122/97 -GPANFPRIARLNAGWIAISP--------------SPQRLSGP-------
Rv3079c|M.tuberculosis_H37Rv -GPANFPRIARLNAGWIAISP--------------SPQRLSGP-------
Mflv_4097|M.gilvum_PYR-GCK NTSAARARVAKYAQGWCPFRAPAMLAQTARTAALETTEHLAKG-------
Mvan_2248|M.vanbaalenii_PYR-1 NTSAARARVARYAQGWCPFRAPAVLAQTARTAALETVEHLKAG-------
TH_2146|M.thermoresistible__bu NTGAARQRVADHGAGWCPFPAPAVLAQTARTAAMDSAEALAAG-------
MMAR_0393|M.marinum_M NTAAARRRVAAHGDGWCPFPAPAPLAQTAGTAAIDSADRLAAG-------
MUL_1043|M.ulcerans_Agy99 NTAAARRRVAVHGDGWCPFPAPAPLAQTAGTAAIDSADRLAAG-------
MAV_5129|M.avium_104 NTAAARQRVADYGDGWCPFPAPPQLARTAGTAVIDSVAKLADG-------
MSMEG_4820|M.smegmatis_MC2_155 NTAAARARVARHGDGWCPFAAPPGLAQTAGTAAIDSIERLAAG-------
MAB_0366|M.abscessus_ATCC_1997 HSKAAARRAGRLGSGFQPLGLVG--------------DDLTAA-------
MLBr_00131|M.leprae_Br4923 HGPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSITP
. .: .:
Mb3106c|M.bovis_AF2122/97 --LQRLRAMAGG--------DVPVTVCQWGEAAAK---------------
Rv3079c|M.tuberculosis_H37Rv --LQRLRAMAGG--------DVPVTVCQWGEAAAK---------------
Mflv_4097|M.gilvum_PYR-GCK --IDDLRRRLEDAGRDPADVDITFTNDAGGAPGTD---------------
Mvan_2248|M.vanbaalenii_PYR-1 --IDDLRRRLEGTGRDPFDIDITFTNDAGGSPGAA---------------
TH_2146|M.thermoresistible__bu --ITDLHRRLEATGRDPADVDVVFSNLTGGTPGRA---------------
MMAR_0393|M.marinum_M --IDDLRRKCDAAGRDFSAIDVTFTNFDGGGPASA---------------
MUL_1043|M.ulcerans_Agy99 --IDDLRRKCDAAGRDFSAIDVTFTNFDGGGPASA---------------
MAV_5129|M.avium_104 --IADLRRRCDAAQRDWSTIDITFTNFEGGSPADD---------------
MSMEG_4820|M.smegmatis_MC2_155 --IADLRAKLDAAQRDPSTVDIVFTNFDGGNPGDD---------------
MAB_0366|M.abscessus_ATCC_1997 --VGVMRAAAVDAGRDPRGLDLVLG-HGLHRVDQA---------------
MLBr_00131|M.leprae_Br4923 AAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFA
: : .: .
Mb3106c|M.bovis_AF2122/97 ----------------DLEGYRHLG---------VERVLLELPTEPRDPT
Rv3079c|M.tuberculosis_H37Rv ----------------DLEGYRHLG---------VERVLLELPTEPRDPT
Mflv_4097|M.gilvum_PYR-GCK ----------------DFNADEFLAGAEELERAGVTWLQVNVPGDSLAHA
Mvan_2248|M.vanbaalenii_PYR-1 ----------------DFNADEFLSGAAELERAGVTWIQVTVPGDSLAHT
TH_2146|M.thermoresistible__bu ----------------DFNADAYLDGVAKLGALGVTWLQVPIPGDSLNHA
MMAR_0393|M.marinum_M ----------------DFNADAYLGGLEKLATLGVTWVHVGLPGDGLAHA
MUL_1043|M.ulcerans_Agy99 ----------------DFNADAYLGGLEKLAMLGVTWVHVGLPGDGLAHA
MAV_5129|M.avium_104 ----------------EFNADAYLDGLDKLAKLGVTWVSVHLPGDSMAHA
MSMEG_4820|M.smegmatis_MC2_155 ----------------DFDADAYLAGVDQLAALGVTWLHVTIPGDSLAHA
MAB_0366|M.abscessus_ATCC_1997 ----------------ALDQAAHAG-------AGRMLLSASRRATTLEAV
MLBr_00131|M.leprae_Br4923 GVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHG
Mb3106c|M.bovis_AF2122/97 LRYLDKLQAELARLA---------------------
Rv3079c|M.tuberculosis_H37Rv LRYLDKLQAELARLA---------------------
Mflv_4097|M.gilvum_PYR-GCK VEAIEGFGETVIAQR---------------------
Mvan_2248|M.vanbaalenii_PYR-1 LEAIEEFGGSVIGRP---------------------
TH_2146|M.thermoresistible__bu LEAIEAFGSEVIGKL---------------------
MMAR_0393|M.marinum_M LECIDRFRVQVIEAA---------------------
MUL_1043|M.ulcerans_Agy99 LECIDRFRVQVIEAA---------------------
MAV_5129|M.avium_104 LETLDRFRTLVVDAA---------------------
MSMEG_4820|M.smegmatis_MC2_155 LETIEGFGKSVIAR----------------------
MAB_0366|M.abscessus_ATCC_1997 LEEMAGCATRLELGGPR-------------------
MLBr_00131|M.leprae_Br4923 LKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL
:. : :