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TKAVIVTGAAGGIGAALCERVRKDGYLAVGIDRSPAPAADADIRLDLSESEQLVDVGRELGEKYELKAVV HNAAAQPIAGAGDTPLADWVEALRVNVIAVDALMSGTRVNLAANDGSVIVISSAHARATTGGVTAYATTK AALEGWVRSAALDLGPGVRVNAVAPGAIDTAKLREGFARWGEESAEARKAILRQRTALRRIGEPSDVAGA VSFLIGDDARFITGTVLVVDGGATARLGSE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4767 | - | - | 100% (241) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_2501 | - | 2e-25 | 33.47% (236) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_4508 | - | 5e-25 | 31.60% (250) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0950c | - | 2e-23 | 34.68% (248) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0927c | - | 2e-23 | 34.68% (248) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-17 | 29.11% (237) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4632 | - | 5e-24 | 31.43% (245) | short chain dehydrogenase |
| M. marinum M | MMAR_4765 | - | 1e-25 | 36.47% (255) | short chain dehydrogenase |
| M. avium 104 | MAV_0942 | - | 6e-24 | 32.78% (241) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. smegmatis MC2 155 | MSMEG_6538 | - | 3e-26 | 33.89% (239) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. thermoresistible (build 8) | TH_4254 | - | 9e-25 | 34.13% (252) | PUTATIVE putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol |
| M. ulcerans Agy99 | MUL_0336 | - | 7e-25 | 36.05% (258) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1861 | - | 2e-27 | 32.41% (253) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0942|M.avium_104 --------------------MKTAVVTGGGSGIGLAVVERLRADGLNVAS
MSMEG_6538|M.smegmatis_MC2_155 ------------------MTAKTALVTGGASGIGKAIAERLASDGHQVAI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
Mvan_1861|M.vanbaalenii_PYR-1 ------------MPMHNRLLGKGVLVTGAASGIGEATVRRLLDEGASVVG
TH_4254|M.thermoresistible__bu -----------MTAGSTRLAGKVVLVTGAGGGLGTAIARRLADEGARLVL
Mb0950c|M.bovis_AF2122/97 -----------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLI
Rv0927c|M.tuberculosis_H37Rv -----------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLI
MAB_4632|M.abscessus_ATCC_1997 -----------MILDRFKLDGNVAVVTGAGRGLGAAIAEAFAQAGADVLI
MMAR_4765|M.marinum_M ------------MVD--ELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MUL_0336|M.ulcerans_Agy99 ------------MVD--ELAGKIAIVTGGASGIGRATVARFIAEGARVVI
Mflv_4767|M.gilvum_PYR-GCK -------------------MTKAVIVTGAAGGIGAALCERVRKDGYLAVG
. ::**. *:* * . *
MAV_0942|M.avium_104 IDLR--PSDAELA-----------FTADVTDRSQVDAALSAIRAQLGPVT
MSMEG_6538|M.smegmatis_MC2_155 LDLN--PGDGPHA-----------YTADVTDRAQVDGVFKAVREELGPVS
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFG-----------VECDVTDNDAIGAAFKAVEEHQGPVE
Mvan_1861|M.vanbaalenii_PYR-1 CDLAPGPPSDLPGDIGY-------LSGDVRDTATAERAVAAVIERTGRLD
TH_4254|M.thermoresistible__bu ADLQESQCAALADELPAPAGAHHPLGFDVADETAWISAISTVSAQYGALH
Mb0950c|M.bovis_AF2122/97 ASRTSSELDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLD
Rv0927c|M.tuberculosis_H37Rv ASRTSSELDAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLD
MAB_4632|M.abscessus_ATCC_1997 ASRTESQLREVAAKVQAAGRQAEVVVADLSDTEASAALAQKAVDRFGRLD
MMAR_4765|M.marinum_M ADVEEERGESLAAALGAD---AMFCRTDVSQPEQVAAVVAAAVENFGGLH
MUL_0336|M.ulcerans_Agy99 ADVEEERGESLAAALGAD---AMFCRTDVSQPEQVAAVVAAAVDNFGGLH
Mflv_4767|M.gilvum_PYR-GCK IDRSP------APAADAD------IRLDLSESEQLVDVGRELGEKY-ELK
*: . :
MAV_0942|M.avium_104 VLVNAAG--LDGFKKFNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEAG
MSMEG_6538|M.smegmatis_MC2_155 ILVNAAG--LSDFTPFTDISFDHWQRVVNVNLHGVFHVVQAALPDMVAAG
MLBr_01807|M.leprae_Br4923 VLVANAG--ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
Mvan_1861|M.vanbaalenii_PYR-1 GVVHSAG--VGGGGPIHLLPDAEWDRVLDVNLKGTFVVLRAALAQMITQD
TH_4254|M.thermoresistible__bu ALVNNAA--IGALGNVAEERLERWDRILDVGATGVWLGMKHAVPLIRRSG
Mb0950c|M.bovis_AF2122/97 IVVNNVG--GTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHS
Rv0927c|M.tuberculosis_H37Rv IVVNNVG--GTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHS
MAB_4632|M.abscessus_ATCC_1997 VVVNNVG--GTMPKPFLDTTNDDLAEAFSFNVLSGHALLRAAVPHLLK-S
MMAR_4765|M.marinum_M VMVNNAGVSGVMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAA-H
MUL_0336|M.ulcerans_Agy99 VMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAA-H
Mflv_4767|M.gilvum_PYR-GCK AVVHNAA--AQPIAGAGDTPLADWVEALRVNVIAVDALMSGTRVNLAA--
:* .. . .. . :
MAV_0942|M.avium_104 -----WGRIVNISSSSTHSG-APYMSHYVAAKSAVNGLTKSLALEYGPKG
MSMEG_6538|M.smegmatis_MC2_155 -----WGRIVNISSSSTHSG-VPYMSSYVSAKSAVNGLTKSLALEFGPAG
MLBr_01807|M.leprae_Br4923 -----FGRYIFMGSVVGLSG-VPGQANYAASKSGLIGMARSLARELGSRS
Mvan_1861|M.vanbaalenii_PYR-1 RVDGERGAIVTLSSIEGLEG-TAGGSAYNASKGGVVLLTKNAAIDYGPSG
TH_4254|M.thermoresistible__bu -----GGSVVNICSIFGTVGGFGDSAAYHAAKGAVRTLTKNAALHWAPDG
Mb0950c|M.bovis_AF2122/97 ----GGGSVINISSTMGRLA-ARGFAAYGTAKAALAHYTRLAALDLCP-R
Rv0927c|M.tuberculosis_H37Rv ----GGGSVINISSTMGRLA-ARGFAAYGTAKAALAHYTRLAALDLCP-R
MAB_4632|M.abscessus_ATCC_1997 ----DNASVINITSTMGRLP-GRAFLGYCTAKGALAHYTRTAAMDLSP-R
MMAR_4765|M.marinum_M ----GGGSIVNLTSIGGIQA-GGGVMTYRASKAAVIQFTKSAAIELAHYE
MUL_0336|M.ulcerans_Agy99 ----GGGSIVNLTSIGGIQA-GGGVMTYRASKGAVIQFTKSAAIELAHYE
Mflv_4767|M.gilvum_PYR-GCK ----NDGSVIVISSAHARAT-TGGVTAYATTKAALEGWVRSAALDLGP-G
. : : * * ::*..: .: * .
MAV_0942|M.avium_104 ITVNAVPPGFIDTPMLR-AAEKNG-------FLGDIEETIARTPVRRMGT
MSMEG_6538|M.smegmatis_MC2_155 ITVNAVPPGFIDTPMLR-AAEARG-------ELGDIDDTIAATPVRRMGR
MLBr_01807|M.leprae_Br4923 ITANVVAPGFIDTEMTR-AMDSK-----------YQEAALQAIPLGRIGA
Mvan_1861|M.vanbaalenii_PYR-1 IRVNAICPGFIETPLFESVIGIPG-------MEGPRDGLRHEHKLRRFGR
TH_4254|M.thermoresistible__bu VRVNSLHPGFIETPQLR---ELYK-------GTERYERMLAGTPLGRLGR
Mb0950c|M.bovis_AF2122/97 VRVNAIAPGSILTSALEVVAA----------NDELRAPMEQATPLRRLGD
Rv0927c|M.tuberculosis_H37Rv VRVNAIAPGSILTSALEVVAA----------NDELRAPMEQATPLRRLGD
MAB_4632|M.abscessus_ATCC_1997 IRVNGIAPGSILTSALEVVAG----------NDEMRNTLEQNTPLHRLGD
MMAR_4765|M.marinum_M IRVNAIAPGNIPTPLLASSAAGMDQEQVERFTAQIRQTMREDRPLKREGT
MUL_0336|M.ulcerans_Agy99 IRVNAIAPGNIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKREGT
Mflv_4767|M.gilvum_PYR-GCK VRVNAVAPGAIDTAKLREGFARWGEES----AEARKAILRQRTALRRIGE
: .* : ** * * : * *
MAV_0942|M.avium_104 PQDIAAACAFLVSEEAGYITGQILGVNGGRNT---------------
MSMEG_6538|M.smegmatis_MC2_155 PEDIAATCSFLISEEAGYITGQIIGVNGGRNT---------------
MLBr_01807|M.leprae_Br4923 VEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-------------
Mvan_1861|M.vanbaalenii_PYR-1 PEEVAAVAAFLVSSDAAFVSGQAIAVDGGYTAGRDHHVTELMGLGGP
TH_4254|M.thermoresistible__bu PDEIAAVVAFLVSDDASFITGSEVYADGGWTAR--------------
Mb0950c|M.bovis_AF2122/97 PVDIAAAAVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL-----
Rv0927c|M.tuberculosis_H37Rv PVDIAAAAVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL-----
MAB_4632|M.abscessus_ATCC_1997 PADIAAAAVYLASPAGSFLTGKVLEVDGGLIAPNLDIPLPDLA----
MMAR_4765|M.marinum_M PEDIAEAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MUL_0336|M.ulcerans_Agy99 PEDIAEAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
Mflv_4767|M.gilvum_PYR-GCK PSDVAGAVSFLIGDDARFITGTVLVVDGGATARLGSE----------
::* . :: . . :::* : .:**