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KNAVVTGGASGIGAAVVERLRADGLQVATIDLNPGDAKFSYAADVTDRSAVDAALDEIRAELGPVTVLVN AAGLDRFKKFLDLSFEEWQKVVDVNLNGVFHCTQAVLPDMIEAGWGRIVNISSSSTHSGQPYMSPYVAAK SAVNGLTKSLALEYGPAGITVNAVPPGFIDTPMLRKAEQRGFLGDTEQQIQQTPVRRMGRPEDIAAACAF FISEEAGYITGQILGVNGGRNT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2501 | - | - | 100% (233) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_2469 | - | 3e-64 | 52.92% (240) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1258 | - | 2e-52 | 43.33% (240) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1519 | fabG1 | 1e-37 | 37.66% (231) | 3-oxoacyl- |
| M. tuberculosis H37Rv | Rv1483 | fabG1 | 1e-37 | 37.66% (231) | 3-oxoacyl- |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-40 | 41.13% (231) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2723c | - | 4e-36 | 34.63% (231) | 3-oxoacyl- |
| M. marinum M | MMAR_4715 | - | 1e-101 | 75.97% (233) | 3-oxoacyl- |
| M. avium 104 | MAV_0942 | - | 1e-108 | 82.40% (233) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. smegmatis MC2 155 | MSMEG_4800 | - | 1e-113 | 84.55% (233) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. thermoresistible (build 8) | TH_3102 | - | 1e-108 | 79.83% (233) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 4e-99 | 75.65% (230) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_4157 | - | 1e-123 | 92.27% (233) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2501|M.gilvum_PYR-GCK MK--------------------NAVVTGGASGIGAAVVERLRADGLQVAT
Mvan_4157|M.vanbaalenii_PYR-1 MK--------------------NAVVTGGASGIGAAIAERLRADGMRVAT
MSMEG_4800|M.smegmatis_MC2_155 MK--------------------NAVVTGGGSGIGAAIVARLRADGLNVAS
TH_3102|M.thermoresistible__bu LK--------------------NAVVTGGGSGIGQAVAARLRADGYHVAT
MMAR_4715|M.marinum_M MK--------------------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99 MRPDSSPS----------WCTITSVVTGGASGIGLAIARRLSADGTDVAT
MAV_0942|M.avium_104 MK--------------------TAVVTGGGSGIGLAVVERLRADGLNVAS
Mb1519|M.bovis_AF2122/97 MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
Rv1483|M.tuberculosis_H37Rv MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_2723c|M.abscessus_ATCC_199 MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAV
: . :**** *** *:. ** *** **
Mflv_2501|M.gilvum_PYR-GCK IDLNPGDAK--FSYAADVTDRSAVDAALDEIRAELGPVTVLVNAAGLDRF
Mvan_4157|M.vanbaalenii_PYR-1 IDLNPGDEK--FSYAADVTDRAAVDAVLSEIHTELGPVTVLVNAAGLDRF
MSMEG_4800|M.smegmatis_MC2_155 LDLQPSDDE--FSHVADVTDRVAVDAAMNAVRAQLGPVSVLVNAAGLDCF
TH_3102|M.thermoresistible__bu IDLKPGDDE--FSHAADVTDRAQVDAAFDAIRTQLGPVTILVNAAGLDLF
MMAR_4715|M.marinum_M LDLKTPDGE--LAFSADVTNRSQVDAALTAIRQRLGPVTILVNAAGLDGF
MUL_0315|M.ulcerans_Agy99 LDLKTPDGG--LAFSADVTNRSQVDAALAAIRQRLGPVTILVNAAGLDGF
MAV_0942|M.avium_104 IDLRPSDAE--LAFTADVTDRSQVDAALSAIRAQLGPVTVLVNAAGLDGF
Mb1519|M.bovis_AF2122/97 THRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSAD
Rv1483|M.tuberculosis_H37Rv THRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSAD
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAGITSD
MAB_2723c|M.abscessus_ATCC_199 THRGSGAPEGLLGVQCDITDNDQIDAAFKEVEEKQGPVEVLVANAGITAD
. . :. .*:*: :. .: :. . *** :** **:
Mflv_2501|M.gilvum_PYR-GCK KKFLDLSFEEWQKVVDVNLNGVFHCTQAVLPDMIEAGWGRIVNISSSSTH
Mvan_4157|M.vanbaalenii_PYR-1 KKFLDLTFDEWQKVVDVNLNGVFHCTQAVLPDMIEAGWGRIVNISSSSTH
MSMEG_4800|M.smegmatis_MC2_155 KRFTDISFEKWQQVIDVNLNGVFHCVQAVLPDMIEAGWGRIVNISSSSTH
TH_3102|M.thermoresistible__bu RRFTDISFEDWERVINVNLHGVFHCIQAVLPDMIEAGWGRIVNISSSSTH
MMAR_4715|M.marinum_M KRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWGRIVNISSSSTH
MUL_0315|M.ulcerans_Agy99 KRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWGRIVNISSSSTH
MAV_0942|M.avium_104 KKFNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEAGWGRIVNISSSSTH
Mb1519|M.bovis_AF2122/97 AFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVSGS
Rv1483|M.tuberculosis_H37Rv AFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVSGS
MLBr_01807|M.leprae_Br4923 MLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFMGSVVGL
MAB_2723c|M.abscessus_ATCC_199 MLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFGRLIFMGSVAGQ
: :: :.: :*::.** *.*: : . .* :** : :.*
Mflv_2501|M.gilvum_PYR-GCK SGQPYMSPYVAAKSAVNGLTKSLALEYGPAGITVNAVPPGFIDTPMLRKA
Mvan_4157|M.vanbaalenii_PYR-1 SGQPYMSPYVAAKSAVNGLTKSLALEYGPDGITVNAVPPGFIDTPMLRKA
MSMEG_4800|M.smegmatis_MC2_155 SGQPYMAPYVAAKSAVNGLTKSLALEYGPNGITVNAVPPGFIDTPMLRKA
TH_3102|M.thermoresistible__bu SGAPYMAPYVAAKSGVNGLTKTLALEYGPAGITVNAVPPGFIDTPMLRAA
MMAR_4715|M.marinum_M SGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPPGFIDTPMLRNA
MUL_0315|M.ulcerans_Agy99 SGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPPGFIDTPMLRNA
MAV_0942|M.avium_104 SGAPYMSHYVAAKSAVNGLTKSLALEYGPKGITVNAVPPGFIDTPMLRAA
Mb1519|M.bovis_AF2122/97 WGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTRAL
Rv1483|M.tuberculosis_H37Rv WGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTRAL
MLBr_01807|M.leprae_Br4923 SGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMTRAM
MAB_2723c|M.abscessus_ATCC_199 IGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAPGFIDTDMTREL
* : * *:*:.: *:::::: * . .:*.*.*.**:*** * *
Mflv_2501|M.gilvum_PYR-GCK EQRGFLGDTEQQIQQTPVRRMGRPEDIAAACAFFISEEAGYITGQILGVN
Mvan_4157|M.vanbaalenii_PYR-1 EQRGFLGDTQKQIEQTPVRRMGRPEDIAAACSFLISEEAGYITGQILGVN
MSMEG_4800|M.smegmatis_MC2_155 EDKGFLGDTERQIAATPVRRMGRPGDIAAACAFLISEEAGYITGQILGVN
TH_3102|M.thermoresistible__bu AAKGYLGDIDKTIEATPVRRMGKPEDIAAACAFLISEEAGYITGQILGVN
MMAR_4715|M.marinum_M AAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEAGYITGQILGVN
MUL_0315|M.ulcerans_Agy99 AAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEAGYITGQILGVN
MAV_0942|M.avium_104 EKNGFLGDIEETIARTPVRRMGTPQDIAAACAFLVSEEAGYITGQILGVN
Mb1519|M.bovis_AF2122/97 DER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVD
Rv1483|M.tuberculosis_H37Rv DER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVD
MLBr_01807|M.leprae_Br4923 DSK----YQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVD
MAB_2723c|M.abscessus_ATCC_199 GEK----HVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSGAVIPVD
. : : * *:* ::*.. ::: * :*.*::* :: *:
Mflv_2501|M.gilvum_PYR-GCK GGRNT--
Mvan_4157|M.vanbaalenii_PYR-1 GGRNT--
MSMEG_4800|M.smegmatis_MC2_155 GGRNT--
TH_3102|M.thermoresistible__bu GGRNT--
MMAR_4715|M.marinum_M GGRNT--
MUL_0315|M.ulcerans_Agy99 GGRNT--
MAV_0942|M.avium_104 GGRNT--
Mb1519|M.bovis_AF2122/97 GGMGMGH
Rv1483|M.tuberculosis_H37Rv GGMGMGH
MLBr_01807|M.leprae_Br4923 GGLGMGH
MAB_2723c|M.abscessus_ATCC_199 GGLGMGH
** .