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VANAGLGFGVLGPLSVTAGGAQLPLGAPKQRAVLAMLLIHRNRPVSVDALIDGVWGAAPVPAARTSIQSY VSTLRRLLRSALPNPNGLLASVPPGYQLNVADADCDLGRFRGHKTAGVQAASRGRFEEASGHLAAALREW RGPVLDDLHNFAFVDAFANLLLEERVAAHTARAEAEIACGRADGVIGELEALVAQHPYREPLWAQLITAY YVTERQSDALGAYRRLKTALAEGLGIDPGPTVKALQQRILRQEPLGPGQPGKAARRAMLSTHKQSTVRSE SAAAVVDNPVVARLRDKAGRHYQLNGVTTRIGRLDDNEIVLDDTEVSRHHAVIIDTGTDFLITDMKSTNG VQVRGRRVQRSATLVDGDHIRIGNSEFVFEIRPA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_0226 | - | - | 100% (384) | EmbR protein |
M. avium 104 | MAV_1418 | - | e-114 | 56.91% (376) | putative transcriptional regulator |
M. avium 104 | MAV_0024 | - | 6e-11 | 43.48% (92) | xyppx repeat-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1298c | embR | 1e-124 | 59.95% (377) | transcriptional regulatory protein EMBR |
M. gilvum PYR-GCK | Mflv_4653 | - | 3e-30 | 31.45% (318) | transcriptional regulator |
M. tuberculosis H37Rv | Rv1267c | embR | 1e-124 | 59.95% (377) | transcriptional regulatory protein EMBR |
M. leprae Br4923 | MLBr_00022 | - | 4e-13 | 36.29% (124) | hypothetical protein MLBr_00022 |
M. abscessus ATCC 19977 | MAB_0039c | - | 1e-10 | 40.86% (93) | hypothetical protein MAB_0039c |
M. marinum M | MMAR_4155 | embR | 1e-123 | 58.51% (376) | transcriptional regulatory protein EmbR |
M. smegmatis MC2 155 | MSMEG_1963 | - | 1e-34 | 38.71% (248) | putative transcriptional regulatory protein |
M. thermoresistible (build 8) | TH_2237 | - | 1e-10 | 43.82% (89) | CONSERVED HYPOTHETICAL PROTEIN TB39.8 |
M. ulcerans Agy99 | MUL_4018 | embR | 1e-122 | 57.98% (376) | transcriptional regulatory protein EmbR |
M. vanbaalenii PYR-1 | Mvan_1815 | - | 3e-29 | 34.13% (252) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4653|M.gilvum_PYR-GCK ----------MRYRLLGPLQVVHGEAAVDIGPRKQRSVLAALLLAQGRVV Mvan_1815|M.vanbaalenii_PYR-1 --------------MLGPLQVVHGETVIDVGPRKQRAVLAVLLLAQGRVV MSMEG_1963|M.smegmatis_MC2_155 --------------MLGPLQVVHSGTPVDIGAPKQRAVLAMLLLAQGRVV MMAR_4155|M.marinum_M MAGSAMVDKRLEFGLLGPLEMTIDGELVPLGTPKQRAVLAMLVINRNRPV MUL_4018|M.ulcerans_Agy99 MAGSAMVDKRLEFGLLGPLEMTIDGELVPLGTPKQRAVLAMLVINRNRPV Mb1298c|M.bovis_AF2122/97 MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPV Rv1267c|M.tuberculosis_H37Rv MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPV MAV_0226|M.avium_104 -----MANAGLGFGVLGPLSVTAGGAQLPLGAPKQRAVLAMLLIHRNRPV MLBr_00022|M.leprae_Br4923 --------------------------------MDNQKELIQRIERKLESS TH_2237|M.thermoresistible__bu --------------------------------MG----LADRIERKLEAT MAB_0039c|M.abscessus_ATCC_199 --------------------------------MG----IVQRFERKLEDV : . : . Mflv_4653|M.gilvum_PYR-GCK STDRLVDVVWGDDVPASATASLQVYISNLRRALRSGAGDRTVSSVAQPIV Mvan_1815|M.vanbaalenii_PYR-1 STDRLADAVWGDDVPASVTASLQVYISNLRRALRD-------SQMASPIV MSMEG_1963|M.smegmatis_MC2_155 SVDRLIDAVWGDDPPASATASLQAYISNLRRALRDGS---DTAQVASPIV MMAR_4155|M.marinum_M GVDSLITALWEEWPPAGARASIHSYVSNLRKLLSGAG-----VDPRAMLA MUL_4018|M.ulcerans_Agy99 GVDSLITALWEEWPPAGARASIHSYVSNLRKLLSGAG-----VDPRAMLA Mb1298c|M.bovis_AF2122/97 GVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAG-----IDPRVVLA Rv1267c|M.tuberculosis_H37Rv GVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAG-----IDPRVVLA MAV_0226|M.avium_104 SVDALIDGVWGAAPVPAARTSIQSYVSTLRRLLRSAL-----PNPNGLLA MLBr_00022|M.leprae_Br4923 IDDAFARMFGGSIVPQEVEALLRREASDGVRSLQGNR---LLAPNEYIIT TH_2237|M.thermoresistible__bu VGDAFARVFGGSIVPQEVEARLRREAQAGARDVGGGR---ILAPNDYVIT MAB_0039c|M.abscessus_ATCC_199 VGDAFARVFGGSIVPQEVQASLRREAADGVRSAGQGR---LLAPNEFFVL * : . . : :: : : Mflv_4653|M.gilvum_PYR-GCK RQPPGYFLDAGPDESDIAVFTAACARAAAAIDGERWDEALAEADTALSLV Mvan_1815|M.vanbaalenii_PYR-1 RQPPGYFLDVGPDEVDVSAFTAGCARAAAAIDAERWEEALTEADTALGLV MSMEG_1963|M.smegmatis_MC2_155 RQPPGYYLDAPADAVDLAQFTAGCQQAAQAVEEQRWVDALTAADEALALW MMAR_4155|M.marinum_M AAPPGYRLSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQHLSRALTQW MUL_4018|M.ulcerans_Agy99 TAPPGYRLSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQHLSRALAQW Mb1298c|M.bovis_AF2122/97 AAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREW Rv1267c|M.tuberculosis_H37Rv AAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREW MAV_0226|M.avium_104 SVPPGYQLNVADADCDLGRFRGHKTAGVQAASRGRFEEASGHLAAALREW MLBr_00022|M.leprae_Br4923 LGVHDLEKMKADPDLTSSAFASDLADYIHEQGWQTYGDVVVRFDQSSSLH TH_2237|M.thermoresistible__bu LSESDYRKVSADPDRTSTTFAKHLEGYIHDQGWQTYGDVVVRFEQSSNLH MAB_0039c|M.abscessus_ATCC_199 LSTADHEKAADDRDLNPDTFAELLREYIRDQGWQTYGEVVVRFEQSPNLH . * : :. : Mflv_4653|M.gilvum_PYR-GCK RGELLEDIGDADWIREDAARFAEMRTECLAGKVMSLLALGKIPAALTAAS Mvan_1815|M.vanbaalenii_PYR-1 RGELLEDMADADWVREAAARVAEMRTECLANKVMALLALGKVPAALTEVS MSMEG_1963|M.smegmatis_MC2_155 RGPFLDDLRDEQWVHEDAARAGELRSECVDHRITALLALGRVSTALAAVT MMAR_4155|M.marinum_M RGPVLDDLRDFQFVDAFATALVEDKILAHTAKAEAEIACGRAAAVITELE MUL_4018|M.ulcerans_Agy99 RGPVLDDLRDFQFVDAFATALVEDKILAHTAKAEAEIACGRAAAVITELE Mb1298c|M.bovis_AF2122/97 RGPVLDDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELE Rv1267c|M.tuberculosis_H37Rv RGPVLDDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELE MAV_0226|M.avium_104 RGPVLDDLHNFAFVDAFANLLLEERVAAHTARAEAEIACGRADGVIGELE MLBr_00022|M.leprae_Br4923 TG----QIRARSVVNPDVEPRPTVNDPVRTQSNQAFSAEPG-VPPMTDNS TH_2237|M.thermoresistible__bu TG----QFRARGLVNPDT----TTGEPAQAQQDRAYTAEPG-VPPMSDNP MAB_0039c|M.abscessus_ATCC_199 TG----QFRTRGVVNPDS----KRDRPHGAVTTAPPTPDPQPGAPMTDNP * :: : . . : Mflv_4653|M.gilvum_PYR-GCK QLGALDPLADRGCRLQMLALYRAGRTADALEVYTRYARRLDAELGLEPGP Mvan_1815|M.vanbaalenii_PYR-1 RLREVDPLGDRSCKLQMLTLYRAGRAAEALEAYTRHARLLDAELGLEPGP MSMEG_1963|M.smegmatis_MC2_155 QLRSAEPLSDRACWLHMLTLYRAGRAPEALDAYTRHAQMLDNELGLVPGA MMAR_4155|M.marinum_M ALTAEHPYREPLWTQLITAYYLTDRQSDALGAYRRVKTTLAEDLGIDPGP MUL_4018|M.ulcerans_Agy99 ALTAEHPYREPLWTQLITAYYLTDRQSDALGAYRRVKTTLAEDLSIDPGP Mb1298c|M.bovis_AF2122/97 ALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGP Rv1267c|M.tuberculosis_H37Rv ALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGP MAV_0226|M.avium_104 ALVAQHPYREPLWAQLITAYYVTERQSDALGAYRRLKTALAEGLGIDPGP MLBr_00022|M.leprae_Br4923 SYRGGQGQGRPSD------DYYGRPQDDPRGADP---QGGQDPRGCYPPK TH_2237|M.thermoresistible__bu SYRGGQGPGRPADDE--YDDRYGRP-DDPRGQYPPADQGGYPPRGGYPEQ MAB_0039c|M.abscessus_ATCC_199 ----GPQQGRPGEEYGREDDRYGRPDQDPRGQQP---QGGQ----GYPPR :. * Mflv_4653|M.gilvum_PYR-GCK ELRDLQTAVLRQAPELSGWPRSPGWTGAAAVTAT--EAVPVRLDTVESAS Mvan_1815|M.vanbaalenii_PYR-1 ELRELQTAVLRQAPELAGWPRSPEWTGAAALPQPQPEPATVPPAAMEAVS MSMEG_1963|M.smegmatis_MC2_155 ELRELQTAILRQAPELAAWPRSPEWTGAEEVHTP----APPHPPVPEPGA MMAR_4155|M.marinum_M TLRALNERILRQEPLDAKMNAKSTAVGTVTVLDQR--------------- MUL_4018|M.ulcerans_Agy99 TLRALNERILRQEPLDAKMNAKSTAVGTVTVLDQR--------------- Mb1298c|M.bovis_AF2122/97 TLRALNERILRQQPLDAKKSAKTTAAGTVTVLDQR--------------- Rv1267c|M.tuberculosis_H37Rv TLRALNERILRQQPLDAKKSAKTTAAGTVTVLDQR--------------- MAV_0226|M.avium_104 TVKALQQRILRQEPLGPGQPGKAARRAMLSTHKQS--------------- MLBr_00022|M.leprae_Br4923 PGS-YPQQAGHPPLHR---PDQGGYPGQGGYEDQR--------------- TH_2237|M.thermoresistible__bu PGGGYPEQQGGYPEQQGGYPDQGGYPPRGGYPDQG--------------- MAB_0039c|M.abscessus_ATCC_199 QGG----------------YEGGGYGQGQPYGQDY--------------- Mflv_4653|M.gilvum_PYR-GCK HRAPLVGRRRELAAAADVLDRVTAGAARWLVLSGPPGIGKTRLAEEIAGL Mvan_1815|M.vanbaalenii_PYR-1 HRAPLVGRERELARAADVLARAAAGATRWLVLSGPPGIGKTRLAEEIAGL MSMEG_1963|M.smegmatis_MC2_155 QRGLLIGRKRELAVATDLLADVAAGETRWLVLSGPPGIGKTRLAEEIT-- MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK VAAGDGDVVWVNCPDERGTPPWWPMRQLVRALGADADEVLEIPPHADPDT Mvan_1815|M.vanbaalenii_PYR-1 VGARGGEVAWVSCPDERATPPWWPMRRLVRALGADADEVLEIPAHADPDT MSMEG_1963|M.smegmatis_MC2_155 -DGCDAEVVWVSCPDERSTPPWWPMRQLVRALGADADEVLEVPPHADPDT MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK ARFLVYERIQRLLESAPRLLAVVVDDVQWADTTSAACLAYIAGTLRDRPV Mvan_1815|M.vanbaalenii_PYR-1 ARFLVYERIQALLEAAPRLLAVVVDDVQWSDTASAACLAYIAGALRDHPV MSMEG_1963|M.smegmatis_MC2_155 ARFQVYERVQALLESTGRPAVVVIDDVQWADSTSASCLAYIAGALRDHPV MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK LVVVTVRDGEHPAEVSRLLSTVARGEANRLIEVPALSSEDVATLANEVAE Mvan_1815|M.vanbaalenii_PYR-1 LVIATVRDGEHAPEVARLLSTVARGEDNRHIEVPALSSADVATLANEVAE MSMEG_1963|M.smegmatis_MC2_155 AIVLTVRDVDHTAEVARLLATVARGDGNRHLALSSLSTDDVAALANQISE MMAR_4155|M.marinum_M ----TMVSGQQAVAYLHTIAS------GHDYPIRTAATRIGRLSDNDIVL MUL_4018|M.ulcerans_Agy99 ----TMVSGQQAVAYLHTIAS------GHDYPIRTAATRIGRLSDNDIVL Mb1298c|M.bovis_AF2122/97 ----TMASGQQAVAYLHDIAS------GRGYPLQAAATRIGRLHDNDIVL Rv1267c|M.tuberculosis_H37Rv ----TMASGQQAVAYLHDIAS------GRGYPLQAAATRIGRLHDNDIVL MAV_0226|M.avium_104 ----TVRSESAAAVVDNPVVARLRDKAGRHYQLNGVTTRIGRLDDNEIVL MLBr_00022|M.leprae_Br4923 --------AYHDQG----QGGYPSPYEQRPATPGGYGSQ---GHDQGYR- TH_2237|M.thermoresistible__bu --------GYPEQGGYPDQGGYPPSYEQRP--PAGYGPPPGGGYDQGYRQ MAB_0039c|M.abscessus_ATCC_199 --------GRPPAG--YDQGGYQ----QRPPQQGGYDQG----------- : Mflv_4653|M.gilvum_PYR-GCK EVVTAAEAAELADRTGGNPFFVSEYARLPREERAGNEIPRAVRSVLDRRL Mvan_1815|M.vanbaalenii_PYR-1 ETVTAAEAAELAARTGGNPFFVSEYARLPREERAGNEIPRAVRSVLDRRL MSMEG_1963|M.smegmatis_MC2_155 DVVDHAEAQILAERTGGNPFFVSEYARLPRAERG--EIPVAVKSVLDRRL MMAR_4155|M.marinum_M DSANVSRHHAVIIDTGTN-YIINDLRSSNGVHVQHQRIRGAVTLNDGDHI MUL_4018|M.ulcerans_Agy99 DSANVSRHHAVIIDTGTN-YIINDLRSSNGVHVQHQRIRGAVTLNDGDHI Mb1298c|M.bovis_AF2122/97 DSANVSRHHAVIVDTGTN-YVINDLRSSNGVHVQHERIRSAVTLNDGDHI Rv1267c|M.tuberculosis_H37Rv DSANVSRHHAVIVDTGTN-YVINDLRSSNGVHVQHERIRSAVTLNDGDHI MAV_0226|M.avium_104 DDTEVSRHHAVIIDTGTD-FLITDMKSTNGVQVRGRRVQRSATLVDGDHI MLBr_00022|M.leprae_Br4923 -PGSYGPPSGGQPGYGG----YGDYGRGPARPDEGSYTPSGFPAPPEQRV TH_2237|M.thermoresistible__bu PPPGYGPP-GGQPGYGAP--PAGEYDYG--RPPGGRPDDYGRPGHPDQ-G MAB_0039c|M.abscessus_ATCC_199 ---GYGAP--PQAPQGG-----GDYGRPPAPPQQGG----GYGAPPQQ-G . * : . Mflv_4653|M.gilvum_PYR-GCK AALDPAVMQVLRAAAVIADVLDSVTVPLLARTTALDLDTLADYLDEAADE Mvan_1815|M.vanbaalenii_PYR-1 AALDPAVVQVLRAAAVIGDVIDASAVPVLAQATRLDLDTLADYLDEAADE MSMEG_1963|M.smegmatis_MC2_155 AGLDPGVLAVLRVAAVIGDPIDADVVPVLARVAKIDFDTLADHLDAAADE MMAR_4155|M.marinum_M RICDHEFTFQLTARNPR--------------------------------- MUL_4018|M.ulcerans_Agy99 RICDHDFTFQLTARNPR--------------------------------- Mb1298c|M.bovis_AF2122/97 RICDHEFTFQISAGTHGGT------------------------------- Rv1267c|M.tuberculosis_H37Rv RICDHEFTFQISAGTHGGT------------------------------- MAV_0226|M.avium_104 RIGNSEFVFEIRPA------------------------------------ MLBr_00022|M.leprae_Br4923 AYPDQGGGY-DQGYQHSG-------------------------------- TH_2237|M.thermoresistible__bu GYPDQGGGYPDQGYGDQGGGYPD--------------------------- MAB_0039c|M.abscessus_ATCC_199 GYGEPPRPN-YGEYEQGG-------------------------------- : Mflv_4653|M.gilvum_PYR-GCK RIIVNSHTGDGYVFAHGLLREQLLTGMPALRRQRVHAKVADVLADSALPD Mvan_1815|M.vanbaalenii_PYR-1 RIVVAAHAGDGYAFAHGLLREQLLASMPALRRQRMHAKVAEVLADSTAPD MSMEG_1963|M.smegmatis_MC2_155 RIVVNAHTGDGYTFAHGLLRDHLMAGLPALRRQRLHAQVAEVLAGNPSDD MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 ----LGYGREDYGRQEYTQYAENLPGGVYAPSSGGYAEPAGRDYDYGQPG TH_2237|M.thermoresistible__bu ----QGYGDQGYGGQPYGRPDYGQQPGQGDYGAGGYGDAGGYGAGYGDPG MAB_0039c|M.abscessus_ATCC_199 -----GYGGGQYGGQQGPPPGQDYGRPPAYPQQGGYGAPP-QQGGYGSPE Mflv_4653|M.gilvum_PYR-GCK APTWRAQHLVAAQPLVEPTVVVPACRLAAEQATQQWSSDIAAGWWQAALD Mvan_1815|M.vanbaalenii_PYR-1 APTRRAQHLIAAQPLVEPAAVVQACRLAAEQATAQWSSDIAAGWWQAALD MSMEG_1963|M.smegmatis_MC2_155 AITRRAQHLVAAQPLVDPVEVVAACRLAAEAATQRWSSDIAAGWWQAALD MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 AAN-DYSQPVIGGYGGYG--------ALG--SAVILQLDDGSGRTYQLRE TH_2237|M.thermoresistible__bu RGDYDYAGAGYGQDAGYGRQDYQQPPATGRPTTVTLQLDDGSGRTYQLRE MAB_0039c|M.abscessus_ATCC_199 YGD--YEQGGYQSSPDYG---APAGGPGGGRTTVTLQLDDGSGRTYQLRE Mflv_4653|M.gilvum_PYR-GCK AYDRLPASERDDADRDALTVELLEAHSRAGRGQLVLDSVTRYLGEALRTG Mvan_1815|M.vanbaalenii_PYR-1 AYDRLPASERDDTERDALTVELLEAHSRAGRGQLVLDSVQRYLGEALRTG MSMEG_1963|M.smegmatis_MC2_155 AYDRVPVASRSETERDALTVAMLEAHSRAGRGRTVLGYVERHLTEALRNE MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 GSNIVGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNA TH_2237|M.thermoresistible__bu GANVIGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNA MAB_0039c|M.abscessus_ATCC_199 GTNVIGRGQDAQFRLPDTGVSRRHLEVRFDGHAALLSDLNSTNGTTVNNA Mflv_4653|M.gilvum_PYR-GCK RAASAGRVASALLRASGGWPWLAPGNDPGELLTLLSRAATLSEGEPASAA Mvan_1815|M.vanbaalenii_PYR-1 RAASAGRVASALLRASGGWPWLAPGHDPGELLALLGRAATLSEGQPASAA MSMEG_1963|M.smegmatis_MC2_155 RADTAGLVASVLLRSSGGWPWLAPGDDPGALLTLLQRAAEMAAEHPAAGA MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 PVQEWQLADGDVIRLGHSEIIVRIH------------------------- TH_2237|M.thermoresistible__bu PVQEWQLADGDVIRLGHSEIIVRMH------------------------- MAB_0039c|M.abscessus_ATCC_199 PVTEWQLADGDIIRLGHSEIIVRVQ------------------------- Mflv_4653|M.gilvum_PYR-GCK RVLPALAVGHCYHPDPTIAPELLDRAERLAEATGDPDVIADVLIGRLITF Mvan_1815|M.vanbaalenii_PYR-1 RVLPALAVGHCYHPDRRVAEDLLDRAERLAEETGDPDVLADVLMGRLITF MSMEG_1963|M.smegmatis_MC2_155 RVLAALGVGCCYHPDPGVAAGHLDRAERLAERTEDPDVLADVLMGRLITY MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK SGVATLSAQSLEWVQRLNALRHSRSREDAVIAHSVATMAAMNLGDVDGAR Mvan_1815|M.vanbaalenii_PYR-1 SGVATVSHETLQWVERLNALGHKRSREDSVIAHSVATMAAMNLGDVAATR MSMEG_1963|M.smegmatis_MC2_155 SGVNERSHEIFEWVARLEVLQHSRSREDSVIAHSVATMSAMLLADTELTE MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK RHVQAGIAGSEELQLPVLRAQLRWMEAVLAVWHGDFAEAGRHHAIAAHVH Mvan_1815|M.vanbaalenii_PYR-1 RHVEAGIAGSEELQLPVLRAQLRWMEAVLAMWIGDFAEAARHHAIAAHVH MSMEG_1963|M.smegmatis_MC2_155 RHLRAGVVGSEELQLPVLRAQLRWMEAVLATWRGDFDEAQRHHSIAAHVH MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK EQTELYEAGSGLLARATLLRERGGPVDPSWTDLNA-QQAGGLGMVGVVRT Mvan_1815|M.vanbaalenii_PYR-1 EQTELYEAGSGLLATASLVRERGGPVDAGWAAVQASKETGGQDMVGVVRT MSMEG_1963|M.smegmatis_MC2_155 EQTELYGAGSGLLAEVTLLREIGGPVPAGFGVTPADVERGGQGMEAMVHV MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK GVLTLLSGPKARAEALATLRHWAQH-TDRAHIWTTLGHHTLLAHLAVDHD Mvan_1815|M.vanbaalenii_PYR-1 ALLTLESGPQARAEAVARLRKWARTSTGRGDIWTTLGHHALLAHMAADHG MSMEG_1963|M.smegmatis_MC2_155 ALLTIERGP--RAAAATRLDNWVNT--DRGQIWTNLGEAAWMAHLAVDYG MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK LPDFAEPLLAQLDPYRDRIAVIGQVGMAGPVALATARLHALRGDKAAALA Mvan_1815|M.vanbaalenii_PYR-1 LDEFAEPLLAELDPFRDRIAVLGQVGMAGPVALATARLHALRGDTRRALA MSMEG_1963|M.smegmatis_MC2_155 LGEYAEPLLAVLQPFTDRIAVIGQVGHAGPVALATARLHALRGDRARALE MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK DLALARSIAERSAGVPTLLRCRLLECELTEESPGRSTAASTLAAEAADLG Mvan_1815|M.vanbaalenii_PYR-1 DVTVARQIAERSAGVPTLLRCRLLVCQLAEPSADRAADAAALATEADSVG MSMEG_1963|M.smegmatis_MC2_155 DLAKAEDVARRTGARPTLMRCALLACELAEDGAARRQAAAKLAADAEAMG MMAR_4155|M.marinum_M -------------------------------------------------- MUL_4018|M.ulcerans_Agy99 -------------------------------------------------- Mb1298c|M.bovis_AF2122/97 -------------------------------------------------- Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0226|M.avium_104 -------------------------------------------------- MLBr_00022|M.leprae_Br4923 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAB_0039c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_4653|M.gilvum_PYR-GCK MAAVAEAASRLL Mvan_1815|M.vanbaalenii_PYR-1 MAAVAAAARRLA MSMEG_1963|M.smegmatis_MC2_155 MHGIAAQARSLS MMAR_4155|M.marinum_M ------------ MUL_4018|M.ulcerans_Agy99 ------------ Mb1298c|M.bovis_AF2122/97 ------------ Rv1267c|M.tuberculosis_H37Rv ------------ MAV_0226|M.avium_104 ------------ MLBr_00022|M.leprae_Br4923 ------------ TH_2237|M.thermoresistible__bu ------------ MAB_0039c|M.abscessus_ATCC_199 ------------