For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TGPGPAGLDASDGLVAVGTPIDLDNCAREPIHIPGSVQPRGVLVVVREPEFEVRQVSANVEELLGHPVES VLGRHLSALMGASQAARVQQAASIVGDLHRRNPVECVLDVRGKSLEFDAILHREPGGVLLVELEVAFGAR PYSFPNTYQAVRSSVEALNRATTMADLYDTAARSVRELTGFDRVMVYRYDEEYNGEVVAEAKRDDLNSFL GLHYPSTDIPAQARALYEKNWLRLISDVDYAPVPLVPAVDPAVGKPLDLTHATLRSVSPIHIEYLQNMGV HASMSISLLRHGRLWGLIACHHYAGPHLPPFGNRAAAEFLGSTLSLRLVDQYEDDQLHRRLDAQAVLVKL TAATMNDGKPLVSALLGAPDLLDLVPADGVVVDIGGHHRTRGSVPSPEVVAAVAAWARAAEDEIARSDSL SRTLPDLDVDPALAAGALVLNLPDGQFAAWFRRESLRSVDWGGDPHNKAIAVSEGGEVRLSPRKSFERWQ EIVRDRGEPWTPTEIESADMLRRHLVETLYHRTRGALRVAELVQRSLIPDSIPDLESWELTAHYEPAAGE RVGGDWYDAFELRDGRLIVVVGDVAGHGVTVAGTMAQLRNALRAQLFAGAAPAEAVRQLNDFCVHLLRSA FATVLVARVDLDSGLVEATSAGHLMPYLTEGSATAVAAPIRLSPPIGLSSARYTQSTFTIEPGQCLVLYS DGLVERRGEVIDDGMDRLARGLGECAEPAAYPIWAALASGHTEDDVTVVTLRRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4519 | - | - | 100% (755) | putative GAF sensor protein |
| M. gilvum PYR-GCK | Mflv_4423 | - | 9e-26 | 36.07% (219) | multi-sensor signal transduction histidine kinase |
| M. gilvum PYR-GCK | Mflv_4521 | - | 7e-23 | 33.96% (212) | putative GAF sensor protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1399c | - | 9e-26 | 35.86% (198) | hypothetical protein Mb1399c |
| M. tuberculosis H37Rv | Rv1364c | - | 3e-26 | 36.36% (198) | hypothetical protein Rv1364c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5186 | - | 1e-27 | 30.94% (307) | sensor-component of a two-component regulator |
| M. avium 104 | MAV_1619 | - | 1e-28 | 39.18% (194) | anti-anti-sigma factor |
| M. smegmatis MC2 155 | MSMEG_6131 | - | 8e-13 | 29.95% (207) | magnesium or manganese-dependent protein phosphatase |
| M. thermoresistible (build 8) | TH_2781 | - | 3e-29 | 36.84% (228) | PUTATIVE stage II sporulation protein E (SpoIIE) |
| M. ulcerans Agy99 | MUL_3853 | rsbU | 3e-26 | 38.14% (194) | regulator of sigma subunit, anti-anti-sigma factor RsbU |
| M. vanbaalenii PYR-1 | Mvan_1931 | - | 1e-27 | 37.80% (209) | multi-sensor signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 MTGDGRGESFSPAGIFADGGEVGRDHARVDWAATPLGPPSRWPQSLLTAA
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 SILLSSRFPMWMAWGPELTFFCNDAYRRDTLGRKYPWALGRPASEVWAEI
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 WDDIGPRIERVLSTGQATWDTALLLFLERSGYPEETYHTFSYSPLRDDDG
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 RVVGMLCVVSEDTVRVIGERRMATLRDLGSDLSLVRSEVDILRFADEQLG
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 HNLRDLPFTLTYLFDGDGSARLAGTSGIAPEHPAVPTRLSADGGGIWPVA
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 EPARSESVLVDLDGDSYPSLPTGDWREPPAQALVVPLLHQGGSPSGFLVV
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 GLNRYRLLDDGYRGFLTLVAGHIAAGIGLARSYRAQQRRAEELAELDRVK
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 TTFFSNISHEFRTPLTLILDPVSELRRAESIDEPVRRELDVVWRNGLRLT
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 KLVNTLLDFSRIEAGRTQARYQPVDLGALTAELASMFRSAVERAGLTFDI
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 DCDPLDEVVYVDRDMWEKVIFNLLSNALKFTFEGAVSVRVRRDGHQAVVV
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mvan_1931|M.vanbaalenii_PYR-1 VADTGTGVPADEMPRLFERFHRIENAKARSNEGSGIGLALVKELIGLHGG
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 -------------MLLLDLLRQRTYS------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MMAR_5186|M.marinum_M -------------MTETGDFGAVDA-------------------------
TH_2781|M.thermoresistible__bu ---------------MSPDFGAR---------------------------
Mvan_1931|M.vanbaalenii_PYR-1 TIVADSAEGQGTAFTIRMPFGAAHLPDDALAPVGDGREAAGGADAYVEEA
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 ---------------------MAAEMDWDKTVGAAEDVRRIFEHIP-AIL
Rv1364c|M.tuberculosis_H37Rv ---------------------MAAEMDWDKTVGAAEDVRRIFEHIP-AIL
MUL_3853|M.ulcerans_Agy99 ----------FVRSVHRRDGYMAAEMDWDKNVGTANTVRRIFENVP-TML
MAV_1619|M.avium_104 ---------------------MVAEKDWDRIVGAADDVRRVFDNVP-ALL
MMAR_5186|M.marinum_M ---------FQTQYADALRAYLDTRDENSLAVGHEFGRRALQEQIS----
TH_2781|M.thermoresistible__bu -------------YAAALAAYLEDSSERRLAVAHDLGRQALLGRIS----
Mvan_1931|M.vanbaalenii_PYR-1 LRWIPADTEADDESAHAPTGSVTAASARVLVADDNADMREYLTRLLRSDG
MSMEG_6131|M.smegmatis_MC2_155 -------------------------------------MRAPFDRVI----
Mflv_4519|M.gilvum_PYR-GCK ------MTGPGPAGLDASDGLVAVGTPIDLDNCAREPIHIPGSVQPRGVL
:
Mb1399c|M.bovis_AF2122/97 VGLEGPDHRFVAVNAAYR------------------GFSPLLDTVGQPAR
Rv1364c|M.tuberculosis_H37Rv VGLEGPDHRFVAVNAAYR------------------GFSPLLDTVGQPAR
MUL_3853|M.ulcerans_Agy99 VGLEGPEHRFVAANAAYR------------------RFSPTFTAVGQPAR
MAV_1619|M.avium_104 VGLEGPDHRFVAVNAAYR------------------ALSPPVDPIGLLAR
MMAR_5186|M.marinum_M -ILDIIENHFRLLDEISP------------------------NPGSDRSV
TH_2781|M.thermoresistible__bu -VLQIVEDHVRLVDELSR------------------------RQPVDTDT
Mvan_1931|M.vanbaalenii_PYR-1 YRVDAVADGLEALEAIRAGAPDIVVSDVMMPRLDGLGLVAELRADRRTAA
MSMEG_6131|M.smegmatis_MC2_155 ------ASPVDLTGPGQR-------------------------------R
Mflv_4519|M.gilvum_PYR-GCK VVVREPEFEVRQVSANVEELLG-------------------HPVESVLGR
.
Mb1399c|M.bovis_AF2122/97 EVYPELEGQQIYEMLDRVYQTGEPQSGSEWRLQTDYDGSG----------
Rv1364c|M.tuberculosis_H37Rv EVYPELEGQQIYEMLDRVYQTGEPQSGSEWRLQTDYDGSG----------
MUL_3853|M.ulcerans_Agy99 EVYPELESQQIYHMLDRVYETGEPQSGAEWRLQADFDGSG----------
MAV_1619|M.avium_104 EVYPELESQQIFQMFDRVYQTGEPQSGTEWRVQADFEGVGK---------
MMAR_5186|M.marinum_M ALEFLLQTLAALDVATRGFLDGTKRYEEQRARAEDLAHRD----------
TH_2781|M.thermoresistible__bu ALQFLLQALAAVDVAVRGYLEGTRRYEQQRARAEGLAGRD----------
Mvan_1931|M.vanbaalenii_PYR-1 TPVLLLSARAGQQESISGLRAGADDYLVKPFAAAELLARVRTNVELARLR
MSMEG_6131|M.smegmatis_MC2_155 LSLLLVEDDRADAILVEELIADAP--------------------------
Mflv_4519|M.gilvum_PYR-GCK HLSALMGASQAARVQQAASIVGDLHRRNPVECVLDVRGKS----------
: .
Mb1399c|M.bovis_AF2122/97 -VEERYFDFVVTPRRR------ADGSIEGVQLIVDDVTSRVRARQAAEAR
Rv1364c|M.tuberculosis_H37Rv -VEERYFDFVVTPRRR------ADGSIEGVQLIVDDVTSRVRARQAAEAR
MUL_3853|M.ulcerans_Agy99 -IDERYFDFLVTPRRR------EDGSIEGVQILFDDVTTRVRARLAAEAR
MAV_1619|M.avium_104 -AQEHFFDFIVTPRRG------DDGSIEGVQLAFVDVTDRVRNRMAAEAR
MMAR_5186|M.marinum_M ----KFRSALVNSLQEGFFVADDEGAVIDMNSAFAEILGYPPEGLPYRWP
TH_2781|M.thermoresistible__bu ----TFRSALVNAMQEAFFVMDRTGSVIDINEAFAEITGYDGHDLPYRWP
Mvan_1931|M.vanbaalenii_PYR-1 HHHAQWRTALVDSLQEAFFVCDADGAVIEINPAFTEILGYDRAGLPYRPM
MSMEG_6131|M.smegmatis_MC2_155 ----------------------------DIDFVWAKSMSDAERTLADHRP
Mflv_4519|M.gilvum_PYR-GCK ----LEFDAILHREPGGVLLVELEVAFGARPYSFPNTYQAVRSSVEALNR
.
Mb1399c|M.bovis_AF2122/97 VEELSER-------YRNVRDSATVMQ---QALLAASVPVVPGADIAAEYL
Rv1364c|M.tuberculosis_H37Rv VEELSER-------YRNVRDSATVMQ---QALLAASVPVVPGADIAAEYL
MUL_3853|M.ulcerans_Agy99 VEELSER-------YRHLRDSAIVMQ---QALLAPSVPVVSGPDIAAQYL
MAV_1619|M.avium_104 LEELSER-------YRNVRDSATVMQ---QALLAPSVPVTPGADVTAEYL
MMAR_5186|M.marinum_M HPWLVDR-------KSAAQQQERVRH---EGS-ADYETPVRHQDGHLSWV
TH_2781|M.thermoresistible__bu HPWVVDE-------PRADEDLLELLQ---HGR-VQLERQIRHRSGHLAWV
Mvan_1931|M.vanbaalenii_PYR-1 HPWWPSADNDPDAHRQVAEAFDSLLG---NRRGTITAVPVTHRDGHRLWV
MSMEG_6131|M.smegmatis_MC2_155 DCVLLDLN------LPDAAGIDALHH---LGKLDARIPIIVLTGLNDEHF
Mflv_4519|M.gilvum_PYR-GCK ATTMADLYDTAARSVRELTGFDRVMVYRYDEEYNGEVVAEAKRDDLNSFL
. : . .
Mb1399c|M.bovis_AF2122/97 VAAEDTAAGGDWFDALALG-------DRLVLVVGDVVGHGVEAAAVMSQL
Rv1364c|M.tuberculosis_H37Rv VAAEDTAAGGDWFDALALG-------DRLVLVVGDVVGHGVEAAAVMSQL
MUL_3853|M.ulcerans_Agy99 VAAQDTAAGGDWFDAVALG-------DRLVLIVGDVVGHGVEAAAVMSQL
MAV_1619|M.avium_104 VAAQDTAAGGDWFDAIPLG-------DRLVLIVGDVVGHGVEAAAVMSQL
MMAR_5186|M.marinum_M AVSINAVRGSGSDRDVYVGTVRDITAERAFAARESAVLRLATSVSVAKSV
TH_2781|M.thermoresistible__bu AISVNVVNPNGT---AFVGTMRDITAAHKAAARESALTRLATAAGVATSV
Mvan_1931|M.vanbaalenii_PYR-1 TATFAHAEDPETGGDVVVGTVRDVSAEHFVVQRETALASLNESLAQADTL
MSMEG_6131|M.smegmatis_MC2_155 GVSAVASG---------------------------AQDYLVKGRVEPEML
Mflv_4519|M.gilvum_PYR-GCK GLHYPSTDIPAQARALYEKNWLRLISDVDYAPVPLVPAVDPAVGKPLDLT
.
Mb1399c|M.bovis_AF2122/97 RTALRMQISTGYTVVEALEAVDRFHKQ------VPGSKSATMCVG-----
Rv1364c|M.tuberculosis_H37Rv RTALRMQISAGYTVVEALEAVDRFHKQ------VPGSKSATMCVG-----
MUL_3853|M.ulcerans_Agy99 RTALRLQIAAGRSIGEALEALDAFHEH------VPGSNSATLCVG-----
MAV_1619|M.avium_104 RTALRMQILAGYPIAEALEAVDRFHKH------VPGSSSATMCVG-----
MMAR_5186|M.marinum_M SEVLSITLEECRTAVDVQRVVAVMWPP-------SDGEPTVQVAGEPAES
TH_2781|M.thermoresistible__bu SEVLSIMLDECRPAIDSRRVIAVTWAR-------EDAEPTIQVVGDPPAS
Mvan_1931|M.vanbaalenii_PYR-1 GDAVRAATAEFAAVWRARRVLAVTWPDGYPVDTETPVDPHLVCAGEPAR-
MSMEG_6131|M.smegmatis_MC2_155 RRAVLYAIERKRAELTS---------------------------------
Mflv_4519|M.gilvum_PYR-GCK HATLRSVSPIHIEYLQNMGVHASMSIS----LLRHGRLWGLIACHHYAGP
.:
Mb1399c|M.bovis_AF2122/97 -SLDFTSGEFQYCTAGHPPPLLVTADASARYVEPTGAGPLGSGTGFPVRS
Rv1364c|M.tuberculosis_H37Rv -SLDFTSGEFQYCTAGHPPPLLVTADASARYVEPTGAGPLGSGTGFPVRS
MUL_3853|M.ulcerans_Agy99 -SLDFTTGEFQYCTAGHPPPLVVTAEAKARYLEPSGAGPLGSDTGFPVRT
MAV_1619|M.avium_104 -SLDFGSGEFSYCTAGHPPPLLVTADATARYVEPSGAGPLGSGTGFPVRT
MMAR_5186|M.marinum_M SWRALDPQLRETFLGARAQLPLTARPIEWPDSPGRAQGLVAVLSGTADVA
TH_2781|M.thermoresistible__bu TWADLDESLRTTLLAARDWPPLTVQPVSDAG-QNTSRGIVAVLSGTPATV
Mvan_1931|M.vanbaalenii_PYR-1 -WSDLPAHTRERITALRDDD------LLDPDTSTAGAAGVALQHPQGVLV
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK HLPPFGNRAAAEFLGSTLSLRLVDQYEDDQLHRRLDAQAVLVKLTAATMN
Mb1399c|M.bovis_AF2122/97 EVLNIGDAILFYTDG----------------LIERPGRPLEASTAEFADL
Rv1364c|M.tuberculosis_H37Rv EVLNIGDAILFYTDG----------------LIERPGRPLEASTAEFADL
MUL_3853|M.ulcerans_Agy99 ELIGVGDVVLLYTDG----------------LIERPGRPLGASTAEFADL
MAV_1619|M.avium_104 EFLDVGDSILLYTDG----------------LIERPGRPLGASTAEFADL
MMAR_5186|M.marinum_M LWLELGAPRWVTAEDRLLVTVLVGHLSLAIGHVRQFESARETSLTLQRAM
TH_2781|M.thermoresistible__bu LWLEHRVPRPVGIDGRRLINALVGHVSLAVQHVRRFEIARESSLTLQRAM
Mvan_1931|M.vanbaalenii_PYR-1 IYVELFERRRFTAEDHTLLTVLAGRLGQGLQRVQQIDQQRETALALQHAI
MSMEG_6131|M.smegmatis_MC2_155 --VDLHASQLRAQEN------------------------ARLERGLLPSP
Mflv_4519|M.gilvum_PYR-GCK DGKPLVSALLGAPDLLDLVPADGVVVDIGGHHRTRGSVPSPEVVAAVAAW
:
Mb1399c|M.bovis_AF2122/97 AASIASGSGGFVLDAPARPIDRLCSDTLELLLRSTGYNDDVTLLAMQRRA
Rv1364c|M.tuberculosis_H37Rv AASIASGSGGFVLDAPARPIDRLCSDTLELLLRSTGYNDDVTLLAMQRRA
MUL_3853|M.ulcerans_Agy99 AANITSG-GGFVIDAQSRPIDRLCSETLELLLRSTGYNDDITLLAVQRRA
MAV_1619|M.avium_104 AANIVSGQGGFVIESSVRTVDRLCAETLELLLRSTGYSDDVTLLAAQRRT
MMAR_5186|M.marinum_M LPPVKPPPGFAVRYEPAVPPLEIGGDWYDVLPIGEHRIGIVVGDCVGRGL
TH_2781|M.thermoresistible__bu LPDIVPPPGFAVRYEPAVRPLEIGGDWYDVLPLDDHQIGIIVGDCVGRGL
Mvan_1931|M.vanbaalenii_PYR-1 LGPALSG-GFAVRYQPATRPLQVGGDWYDVVDLDDGRIALIVGDCVGHGL
MSMEG_6131|M.smegmatis_MC2_155 LLMEGSGVDIVVEARPSRQHALIGGDFYDVVQTPDRTVHVMIGDVAGHGP
Mflv_4519|M.gilvum_PYR-GCK ARAAEDEIARSDSLSRTLPDLDVDPALAAGALVLNLPDGQFAAWFRRESL
: . .
Mb1399c|M.bovis_AF2122/97 PTPPLHITLDATINAARTVRAQLREWLAEIG--ADHSDIADIVHAISEFV
Rv1364c|M.tuberculosis_H37Rv PTPPLHITLDATINAARTVRAQLREWLAEIG--ADHSDIADIVHAISEFV
MUL_3853|M.ulcerans_Agy99 PTPPLNITEDATIHAARAIRSRLRQWLSEIG--ADSGDISDIVHAISEFV
MAV_1619|M.avium_104 PPPPLNLTLDATIHAARTVRTRLRQWLSDVG--ADADDISDIVHAISEFV
MMAR_5186|M.marinum_M PAAAIMGQLRSSARALLLTGAQPALLLEQLD--AAASLIPDAYCTTVFLA
TH_2781|M.thermoresistible__bu PAAAVMGQLRSSARALLLSGAEPARLLENLD--AVAALIPDAYCATVLLA
Mvan_1931|M.vanbaalenii_PYR-1 AAAAIMGQLRSACRALLLEHPSPAAALSGLD--RFAARLPGARCTTAFCA
MSMEG_6131|M.smegmatis_MC2_155 DEAALGVALRIGWRALTFAGLRGNERMRQLDRILTTERPGKGIFATLCSV
Mflv_4519|M.gilvum_PYR-GCK RSVDWGGDPHNKAIAVSEGGEVRLSPRKSFERWQEIVRDRGEPWTPTEIE
* . :
Mb1399c|M.bovis_AF2122/97 ENAVEHGYATDVSKGIVVEAALAGD---------GNVRASVIDRGQWKDH
Rv1364c|M.tuberculosis_H37Rv ENAVEHGYATDVSKGIVVAAALAGD---------GNVRASVIDRGQWKDH
MUL_3853|M.ulcerans_Agy99 ENAVEHGYSTDVSDGLAVAAALGGD---------GKLRVAVIDHGTWKHH
MAV_1619|M.avium_104 ENAVEHGYATEVPDGVVVEAMLAGD---------GNLHASVIDRGRWKDH
MMAR_5186|M.marinum_M ILDTESGILDYSNAGHMPAVLAEPKSGPVLLTDARSVPLAVRRVEPRPEA
TH_2781|M.thermoresistible__bu VLDTESGTLRYSNAGHVPALLAGPGPHATVLTDGASVPLGVQQNRPRPQV
Mvan_1931|M.vanbaalenii_PYR-1 VLDPETGEVVYSCAGHPPPILIGADRSTRLLEEARATPLGLKNPPHRTEA
MSMEG_6131|M.smegmatis_MC2_155 ALEPDSGRFTVVRAGHPGLLVHGNG--------------TVDWLEPRPGA
Mflv_4519|M.gilvum_PYR-GCK SADMLRRHLVETLYHRTRGALRVAELVQRSLIPDSIPDLESWELTAHYEP
Mb1399c|M.bovis_AF2122/97 RDGARGRGRGLAMAEALVSEAR--IMHGAGG---TTATLTHRLSRPARFV
Rv1364c|M.tuberculosis_H37Rv RDGARGRGRGLAMAEALVSEAR--IMHGAGG---TTATLTHRLSRPARFV
MUL_3853|M.ulcerans_Agy99 REGERGRGRGLAMAEALVSETH--VSHDGAG---TTATVVHRLSRPAQFV
MAV_1619|M.avium_104 REGETGRGRGLAMAEALVSEAH--VSHGPEG---TTASVTHRLSRPANFV
MMAR_5186|M.marinum_M TQVLPPGSTLLLFTDGLVERRYESIDEGLGR---VADVVADSVMLPIDAV
TH_2781|M.thermoresistible__bu SRQLTPGSTLMLYTDGLVERRDSPIDTGMDR---ACQVLTAMLDAEPEAV
Mvan_1931|M.vanbaalenii_PYR-1 RETMAPRATLLLYTDGLVERRRESIDDGIAR---AAGVVEDNRATALDEL
MSMEG_6131|M.smegmatis_MC2_155 ALGLGAREWPVNHYELPEGHGLLLLTDGLFE---GHAGRGDERLGESGLL
Mflv_4519|M.gilvum_PYR-GCK AAGERVGGDWYDAFELRDGRLIVVVGDVAGHGVTVAGTMAQLRNALRAQL
: . : :
Mb1399c|M.bovis_AF2122/97 TDTMVRRAAFQQTIDSEFVS-LVESGRIVVRGDVDSTTAATLDRQIAVES
Rv1364c|M.tuberculosis_H37Rv TDTMVRRAAFQQTIDSEFVS-LVESGRIVVRGDVDSTTAATLDRQIAVES
MUL_3853|M.ulcerans_Agy99 TDPVVSRAPNRPAIDSEFASTVTESGHIVVRGDVDSNTAPTLDRQIAVES
MAV_1619|M.avium_104 ADSLVSRAGDHGVRSAEFVSTVTEPGRIVVSGDVDSNTASTLDRQIAVES
MMAR_5186|M.marinum_M ADAVLSQLAPTGGYDDDVAMVAYRYQHGPLRIETSATPDQLVIVRRQLLS
TH_2781|M.thermoresistible__bu ADAMLDTLAPADGYDDDVAIVVYRHTFAPLRIELPATPDRLSEVRARLTG
Mvan_1931|M.vanbaalenii_PYR-1 ANAVMAGLAPADGYHDDVALLLYR-QPAPLDLEFAADVAELAVGREALRG
MSMEG_6131|M.smegmatis_MC2_155 AVARALAATPG--------------------RDFVTSLINEAESRAQTHG
Mflv_4519|M.gilvum_PYR-GCK FAGAAPAEAVRQLNDFCVHLLRSAFATVLVARVDLDSGLVEATSAGHLMP
Mb1399c|M.bovis_AF2122/97 RSGIAPVTIDLSAVTHLGSAGVGALAAACDRARKQGTECVLVAPPGSPAH
Rv1364c|M.tuberculosis_H37Rv RSGIAPVTIDLSAVTHLGSAGVGALAAACDRARKQGTECVLVAPPGSPAH
MUL_3853|M.ulcerans_Agy99 RSGIASLTIDLSAVTHLGSAGVSALVTARDRARKQGGRCVLMAPPGSPAH
MAV_1619|M.avium_104 RSGVAPLTVDLSAVTHLGSAGVSALAAARERALRQGSDYVLVAPPGSPAH
MMAR_5186|M.marinum_M WLQAAEVPDEQAGDIVLVVSEACTNCIEHAYRGQSVGTMLLDVEAADWAI
TH_2781|M.thermoresistible__bu WLTAAGAPELLISDIVLAVNEACTNSVEHAYRDREPGPMQVYADLRDGQI
Mvan_1931|M.vanbaalenii_PYR-1 WLDRAGVGAEQSLDVLIATGEALANAIEHGHREQPRGPVRLRAIALPDRV
MSMEG_6131|M.smegmatis_MC2_155 G----------------LSDDIAVIRVERSRR------------------
Mflv_4519|M.gilvum_PYR-GCK YLTEGSATAVAAPIRLSPPIGLSSARYTQSTFTIEPGQCLVLYSDGLVER
Mb1399c|M.bovis_AF2122/97 HVLSLVQ-----------------LPVVGADTEDIFAQE-----------
Rv1364c|M.tuberculosis_H37Rv HVLSLVQ-----------------LPVVGADTEDIFAQE-----------
MUL_3853|M.ulcerans_Agy99 HVLSLVQ-----------------IPVISGETENVFAED-----------
MAV_1619|M.avium_104 HVLSLVQ-----------------IPVVSGLAENVVAEG-----------
MMAR_5186|M.marinum_M HARVVDSGSWKKPAADPGNG-GRGMTLIRAISDEVEIDNSPGGTAIDMTF
TH_2781|M.thermoresistible__bu MLQVRDFGTWKTPEPNPRIR-GRGLPMMRAISADVQVDNTRSGTVVELTF
Mvan_1931|M.vanbaalenii_PYR-1 HVTVVDSGTWKPPATVPALHRGRGIALMRALMHDVTIDSQTTGTTVHMNA
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4519|M.gilvum_PYR-GCK RGEVIDDGMDRLARGLGECAEPAAYPIWAALASGHTEDDVTVVTLRRP--
Mb1399c|M.bovis_AF2122/97 ---------
Rv1364c|M.tuberculosis_H37Rv ---------
MUL_3853|M.ulcerans_Agy99 ---------
MAV_1619|M.avium_104 ---------
MMAR_5186|M.marinum_M RLPSED---
TH_2781|M.thermoresistible__bu TLSGQPALT
Mvan_1931|M.vanbaalenii_PYR-1 RIV------
MSMEG_6131|M.smegmatis_MC2_155 ---------
Mflv_4519|M.gilvum_PYR-GCK ---------