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MAAEMDWDKTVGAAEDVRRIFEHIPAILVGLEGPDHRFVAVNAAYRGFSPLLDTVGQPAREVYPELEGQQ IYEMLDRVYQTGEPQSGSEWRLQTDYDGSGVEERYFDFVVTPRRRADGSIEGVQLIVDDVTSRVRARQAA EARVEELSERYRNVRDSATVMQQALLAASVPVVPGADIAAEYLVAAEDTAAGGDWFDALALGDRLVLVVG DVVGHGVEAAAVMSQLRTALRMQISTGYTVVEALEAVDRFHKQVPGSKSATMCVGSLDFTSGEFQYCTAG HPPPLLVTADASARYVEPTGAGPLGSGTGFPVRSEVLNIGDAILFYTDGLIERPGRPLEASTAEFADLAA SIASGSGGFVLDAPARPIDRLCSDTLELLLRSTGYNDDVTLLAMQRRAPTPPLHITLDATINAARTVRAQ LREWLAEIGADHSDIADIVHAISEFVENAVEHGYATDVSKGIVVEAALAGDGNVRASVIDRGQWKDHRDG ARGRGRGLAMAEALVSEARIMHGAGGTTATLTHRLSRPARFVTDTMVRRAAFQQTIDSEFVSLVESGRIV VRGDVDSTTAATLDRQIAVESRSGIAPVTIDLSAVTHLGSAGVGALAAACDRARKQGTECVLVAPPGSPA HHVLSLVQLPVVGADTEDIFAQE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1399c | - | - | 100% (653) | hypothetical protein Mb1399c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4423 | - | 1e-48 | 33.50% (406) | multi-sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv1364c | - | 0.0 | 99.69% (653) | hypothetical protein Rv1364c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3991 | rsbU | 0.0 | 77.83% (654) | regulator of sigma subunit, anti-anti-sigma factor RsbU |
| M. avium 104 | MAV_1619 | - | 0.0 | 76.45% (654) | anti-anti-sigma factor |
| M. smegmatis MC2 155 | MSMEG_6131 | - | 8e-16 | 27.92% (265) | magnesium or manganese-dependent protein phosphatase |
| M. thermoresistible (build 8) | TH_2781 | - | 3e-47 | 33.68% (380) | PUTATIVE stage II sporulation protein E (SpoIIE) |
| M. ulcerans Agy99 | MUL_3853 | rsbU | 0.0 | 77.52% (654) | regulator of sigma subunit, anti-anti-sigma factor RsbU |
| M. vanbaalenii PYR-1 | Mvan_3797 | - | 2e-49 | 34.67% (375) | putative GAF sensor protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4423|M.gilvum_PYR-GCK MNWAQTPLGPTSEWPQSLQTAANILLSSRFPMWMAWGPDLTFFCNDAYRN
Mvan_3797|M.vanbaalenii_PYR-1 ---------------------MDELVAAR---------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK VTLGRKYPWALGRPASEVWAEIWDDIGPRIERVLSTGVATWDTSLLLFLE
Mvan_3797|M.vanbaalenii_PYR-1 ------------------------DQMERLVRVIVAIGADLDLDVTLRRI
TH_2781|M.thermoresistible__bu --------------------------------------MSPDFGARYAAA
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK RSGYTEESYHTFSYSPLRDDDGAVVGMLCVVSEDTLQVIGERRMATLRDL
Mvan_3797|M.vanbaalenii_PYR-1 VTGARELSGARYGALGIRGADGTWASFVCDG-------------------
TH_2781|M.thermoresistible__bu LAAYLEDSSERRLAVAHDLGRQALLGRISVLQ------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK GSDPSVVRTEGEILSFVDRQLAQNLRDLPFTLTYLFDDDGSAHLAGMSGI
Mvan_3797|M.vanbaalenii_PYR-1 ----------------MEEDAARALGGLAAGEGIRIDD-----LTGYSGV
TH_2781|M.thermoresistible__bu ----------------IVEDHVRLVDELSRRQPVDTDT------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK TGDHPAAPDVLTGADGELWPVGPPAGGETVLLEVDTAPYPAMPTGDWREP
Mvan_3797|M.vanbaalenii_PYR-1 AGLR-----------------------------------------SQKTP
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK PRQVLIVPLLQQGAAPTGFLVAGLNRYRVLDDAYRGFVALVAGHIAAGIG
Mvan_3797|M.vanbaalenii_PYR-1 MRALLGVPITVRGADFGALYLADDQPDRVFSDSQEGAVRALATAAAAAID
TH_2781|M.thermoresistible__bu ALQFLLQALAAVDVAVRGYLEGTRRYEQQRARAEGLAGRDTFRSALVNAM
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK LSRSYRTQQMRAEELAELDRAKTTFFSNISHEFRTPLTLILDPVSELRRA
Mvan_3797|M.vanbaalenii_PYR-1 NARLFERERESAKWTKASREITTALLS--GDPQTGPLQLIVNLALELADA
TH_2781|M.thermoresistible__bu QEAFFVMDRTGSVIDINEAFAEITGYDGHDLPYRWPHPWVVDEPRADEDL
Mb1399c|M.bovis_AF2122/97 ------------------------------------MAAEMDWDKTVGAA
Rv1364c|M.tuberculosis_H37Rv ------------------------------------MAAEMDWDKTVGAA
MMAR_3991|M.marinum_M ------------------------------------MAAEMDWDKSVGTA
MUL_3853|M.ulcerans_Agy99 ------------MLLLDLLRQRTYSFVRSVHRRDGYMAAEMDWDKNVGTA
MAV_1619|M.avium_104 ------------------------------------MVAEKDWDRIVGAA
MSMEG_6131|M.smegmatis_MC2_155 ----------------------------MRAPFDRVIASPVDLTGPGQRR
:
Mflv_4423|M.gilvum_PYR-GCK DTLGDAARQELDVVWRNGLRLNKLVNTLLDFSRIEAGRTQAHYQPVDLGA
Mvan_3797|M.vanbaalenii_PYR-1 EQAILLVPGEPDLPGD-------------EADTLVVAATAGRYASEVIGR
TH_2781|M.thermoresistible__bu LELLQHGRVQLERQIR---------------------HRSGHLAWVAISV
Mb1399c|M.bovis_AF2122/97 EDVRRIFEHIPAILVG----------------------------------
Rv1364c|M.tuberculosis_H37Rv EDVRRIFEHIPAILVG----------------------------------
MMAR_3991|M.marinum_M NTVRRIFENVPTMLVG----------------------------------
MUL_3853|M.ulcerans_Agy99 NTVRRIFENVPTMLVG----------------------------------
MAV_1619|M.avium_104 DDVRRVFDNVPALLVG----------------------------------
MSMEG_6131|M.smegmatis_MC2_155 LSLLLVEDDRADAILVEEL-------------------------------
Mflv_4423|M.gilvum_PYR-GCK VTAELASVFRSAIERAGLVFDVDCPPLGEEAYVDLDMWEKVIFNLLSNAL
Mvan_3797|M.vanbaalenii_PYR-1 QVPMDGSTTGGVARRG--------------------------LPLITDSF
TH_2781|M.thermoresistible__bu NVVNPNGTA-----------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK KFTFEGSVSVTARRDGRGAVITVSDTGTGVPADEMPRLFERFHRIENTRA
Mvan_3797|M.vanbaalenii_PYR-1 QYPIEG----------------FTDAG-----------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK RSNEGSGIGLALVKELVGLHGGTIEADSAESRGTTFTIRLPWGAGHLPAD
Mvan_3797|M.vanbaalenii_PYR-1 ---ERSAIVMPLIADEAVLG----------------------------VI
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK AVASQPRERRPGNTVDAYVEEALRWTPDGVREYVAESAQPTTGPEKPIGT
Mvan_3797|M.vanbaalenii_PYR-1 AVARRPHQPPFDN-------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK GTLARVLVADDNADMREYLGRLLRSDGYAVEAVVDGWQALEAIRAEPPDL
Mvan_3797|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK VISDVMMPRLDGLGLVAELRADRRTAAVPVLLLSARAGQEASISGLQAGA
Mvan_3797|M.vanbaalenii_PYR-1 ----------DYLELVSDF---ARHAAIALALAAGREH------------
TH_2781|M.thermoresistible__bu -----------FVGTMRDITAAHKAAARESALTR----------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK DDYLVKPFAAAELLARVRANIQLARLREGHARWRTALVDSLQEAFFVCDE
Mvan_3797|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK HGAVVEINPAFTEILGYDSTGLPYPLMHPWWPLKGSDAEANRRVEEAFGS
Mvan_3797|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK FMRDPHGTLTEVPVTHRDGHRLYVTVTFSHADDPETGRDVIVGTLRDVTA
Mvan_3797|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 --------------------------------------------------
Rv1364c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3991|M.marinum_M --------------------------------------------------
MUL_3853|M.ulcerans_Agy99 --------------------------------------------------
MAV_1619|M.avium_104 --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK ERYIVQRESALASLNEKLAQADTLDDAVLAAAEEFSSIWSARRVVAATWP
Mvan_3797|M.vanbaalenii_PYR-1 ------------ALNQELAQADSVDAALHAAAEELRRLWRARRVLAVTFP
TH_2781|M.thermoresistible__bu -------------LATAAGVATSVSEVLSIMLDECRPAIDSRRVIAVTWA
Mb1399c|M.bovis_AF2122/97 -------------LEGPDHRFVAVNAAYRGFSPLLDTVGQPAREVYPELE
Rv1364c|M.tuberculosis_H37Rv -------------LEGPDHRFVAVNAAYRGFSPLLDTVGQPAREVYPELE
MMAR_3991|M.marinum_M -------------LEGPEHRFVAANAAYRRFSPTFTAVGQPAREVYPELE
MUL_3853|M.ulcerans_Agy99 -------------LEGPEHRFVAANAAYRRFSPTFTAVGQPAREVYPELE
MAV_1619|M.avium_104 -------------LEGPDHRFVAVNAAYRALSPPVDPIGLLAREVYPELE
MSMEG_6131|M.smegmatis_MC2_155 -------------IADAPDIDFVWAKSMSDAERTLADHRPDCVLLDLNLP
: :
Mflv_4423|M.gilvum_PYR-GCK DEPDGEHESDAPSLTVVGAPATWDGL-PGSARELILTLRRDHLLAPHTSD
Mvan_3797|M.vanbaalenii_PYR-1 --THGDSVESAPKVVAVGEDTHWADL-SAPTRLTLSALRDGDLLTPNTAQ
TH_2781|M.thermoresistible__bu R----EDAEPTIQVVGDPPASTWADL-DESLRTTLLAARDWPPLTVQPVS
Mb1399c|M.bovis_AF2122/97 GQQIYEMLDRVYQTGEPQSGSEWRLQ-TDYDGSG-VEERYFDFVVTPRRR
Rv1364c|M.tuberculosis_H37Rv GQQIYEMLDRVYQTGEPQSGSEWRLQ-TDYDGSG-VEERYFDFVVTPRRR
MMAR_3991|M.marinum_M SQQIYHMLDRVYETGEPQSGAEWRLQ-ADFDGSG-IDERYFDFLVTPRRR
MUL_3853|M.ulcerans_Agy99 SQQIYHMLDRVYETGEPQSGAEWRLQ-ADFDGSG-IDERYFDFLVTPRRR
MAV_1619|M.avium_104 SQQIFQMFDRVYQTGEPQSGTEWRVQ-ADFEGVGKAQEHFFDFIVTPRRG
MSMEG_6131|M.smegmatis_MC2_155 DAAGIDALHHLGKLDARIPIIVLTGLNDEHFGVSAVASGAQDYLVKGRVE
. . :.
Mflv_4423|M.gilvum_PYR-GCK AG-----AAGVALRHPRGVLVLYVELPEQRLFTAEDDTLLTVLAGRLGQG
Mvan_3797|M.vanbaalenii_PYR-1 PG-----TAGIAMQHPEGILVVWLDLTDQRSFTLEDQTLLTVLAGRLSQG
TH_2781|M.thermoresistible__bu DAGQNTSRGIVAVLSGTPATVLWLEHRVPRPVGIDGRRLINALVGHVSLA
Mb1399c|M.bovis_AF2122/97 ADG-----------SIEGVQLIVDDVTSRVRARQAAEARVEELS------
Rv1364c|M.tuberculosis_H37Rv ADG-----------SIEGVQLIVDDVTSRVRARQAAEARVEELS------
MMAR_3991|M.marinum_M EDG-----------SIEGVQILFDDVTTRVRARLAAEARVEELS------
MUL_3853|M.ulcerans_Agy99 EDG-----------SIEGVQILFDDVTTRVRARLAAEARVEELS------
MAV_1619|M.avium_104 DDG-----------SIEGVQLAFVDVTDRVRNRMAAEARLEELS------
MSMEG_6131|M.smegmatis_MC2_155 PEMLR--------------RAVLYAIERKRAELTSVDLHASQLR------
*
Mflv_4423|M.gilvum_PYR-GCK LQRVHQIDQQRETALALQHAILGPS----LSSAFAVRYQPATRPLQVGGD
Mvan_3797|M.vanbaalenii_PYR-1 LQRVHRVDQQRETALALQHAILGPAD---LPHGFAVRYQAASRPLQVGGD
TH_2781|M.thermoresistible__bu VQHVRRFEIARESSLTLQRAMLPDIV---PPPGFAVRYEPAVRPLEIGGD
Mb1399c|M.bovis_AF2122/97 ----ERYRNVRDSATVMQQALLAASVPVVPGADIAAEYLVAAEDTAAGGD
Rv1364c|M.tuberculosis_H37Rv ----ERYRNVRDSATVMQQALLAASVPVVPGADIAAEYLVAAEDTAAGGD
MMAR_3991|M.marinum_M ----ERYRHLRDSAIVMQQALLAPSVPVVSGADIAAQYLVAAQDTAAGGD
MUL_3853|M.ulcerans_Agy99 ----ERYRHLRDSAIVMQQALLAPSVPVVSGPDIAAQYLVAAQDTAAGGD
MAV_1619|M.avium_104 ----ERYRNVRDSATVMQQALLAPSVPVTPGADVTAEYLVAAQDTAAGGD
MSMEG_6131|M.smegmatis_MC2_155 ---------AQENARLERGLLPSPLLMEGSGVDIVVEARPSRQHALIGGD
::.: : : .... : . ***
Mflv_4423|M.gilvum_PYR-GCK WYDVVDLEDGRIGLIVGDCVGHGLAAATVMGQLRSACRALLLEHPSPAAA
Mvan_3797|M.vanbaalenii_PYR-1 WYDVVDLDDGRIAMIVGDCVGHGLPAATVMGQVRSACRALLFDNPSPAAA
TH_2781|M.thermoresistible__bu WYDVLPLDDHQIGIIVGDCVGRGLPAAAVMGQLRSSARALLLSGAEPARL
Mb1399c|M.bovis_AF2122/97 WFDALALGD-RLVLVVGDVVGHGVEAAAVMSQLRTALRMQISTGYTVVEA
Rv1364c|M.tuberculosis_H37Rv WFDALALGD-RLVLVVGDVVGHGVEAAAVMSQLRTALRMQISAGYTVVEA
MMAR_3991|M.marinum_M WFDAVALGD-RLVLIVGDVVGHGVEAAAVMSQLRTALRLQIAAGRSIGEA
MUL_3853|M.ulcerans_Agy99 WFDAVALGD-RLVLIVGDVVGHGVEAAAVMSQLRTALRLQIAAGRSIGEA
MAV_1619|M.avium_104 WFDAIPLGD-RLVLIVGDVVGHGVEAAAVMSQLRTALRMQILAGYPIAEA
MSMEG_6131|M.smegmatis_MC2_155 FYDVVQTPDRTVHVMIGDVAGHGPDEAALGVALRIGWRALTFAGLRGNER
::*.: * : :::** .*:* *:: :* . *
Mflv_4423|M.gilvum_PYR-GCK LSALDRFAARLPGAR--CTTAFCAVLDPRIGEVVYSCAGHPPPIMVTADR
Mvan_3797|M.vanbaalenii_PYR-1 LAGMDRFAARLPGAQ--CATAVCAVLDPATGELVYSSAGHPPPILMHADG
TH_2781|M.thermoresistible__bu LENLDAVAALIPDAY--CATVLLAVLDTESGTLRYSNAGHVPALLAGPGP
Mb1399c|M.bovis_AF2122/97 LEAVDRFHKQVPGSK--SATMCVGSLDFTSGEFQYCTAGHPPPLLVTADA
Rv1364c|M.tuberculosis_H37Rv LEAVDRFHKQVPGSK--SATMCVGSLDFTSGEFQYCTAGHPPPLLVTADA
MMAR_3991|M.marinum_M LEALDAFHEHVPGSN--SATLCVGSLDFTTGEFQYCTAGHPPPLVVTAEA
MUL_3853|M.ulcerans_Agy99 LEALDAFHEHVPGSN--SATLCVGSLDFTTGEFQYCTAGHPPPLVVTAEA
MAV_1619|M.avium_104 LEAVDRFHKHVPGSS--SATMCVGSLDFGSGEFSYCTAGHPPPLLVTADA
MSMEG_6131|M.smegmatis_MC2_155 MRQLDRILTTERPGKGIFATLCSVALEPDSGRFTVVRAGHPG-LLVHGNG
: :* . . :* *: * . *** ::
Mflv_4423|M.gilvum_PYR-GCK TTELLEGARATPLGLKNPPHRTEARVTMPARATLLLYTDGLVERRRESID
Mvan_3797|M.vanbaalenii_PYR-1 SARLLEGAHTIALGLRVGWSRPEGRLSIPAGATLMLYTDGLVERRRTLLE
TH_2781|M.thermoresistible__bu HATVLTDGASVPLGVQQNRPRPQVSRQLTPGSTLMLYTDGLVERRDSPID
Mb1399c|M.bovis_AF2122/97 SARYVEPTGAGPLGSGTG--FPVRSEVLNIGDAILFYTDGLIERPGRPLE
Rv1364c|M.tuberculosis_H37Rv SARYVEPTGAGPLGSGTG--FPVRSEVLNIGDAILFYTDGLIERPGRPLE
MMAR_3991|M.marinum_M KSRYLEPSGAGPLGSDTG--FPVRTELIGVGDVVLLYTDGLIERPGRPLG
MUL_3853|M.ulcerans_Agy99 KARYLEPSGAGPLGSDTG--FPVRTELIGVGDVVLLYTDGLIERPGRPLG
MAV_1619|M.avium_104 TARYVEPSGAGPLGSGTG--FPVRTEFLDVGDSILLYTDGLIERPGRPLG
MSMEG_6131|M.smegmatis_MC2_155 TVDWLEPRPGAALGLGAR-EWPVNHYELPEGHGLLLLTDGLFEG------
: .** . : ::: ****.*
Mflv_4423|M.gilvum_PYR-GCK DGIARATDVVQ-----------GNRATDLDQLANVIMARLAPADGYHDDV
Mvan_3797|M.vanbaalenii_PYR-1 DGISRAAELLE-----------GHRTSDLEDLADQIMSGLAPSVGYQDDV
TH_2781|M.thermoresistible__bu TGMDRACQVLT-----------AMLDAEPEAVADAMLDTLAPADGYDDDV
Mb1399c|M.bovis_AF2122/97 ASTAEFADLAASIASGSGGFVLDAPARPIDRLCSDTLELLLRSTGYNDDV
Rv1364c|M.tuberculosis_H37Rv ASTAEFADLAASIASGSGGFVLDAPARPIDRLCSDTLELLLRSTGYNDDV
MMAR_3991|M.marinum_M ASTAEFADLAANITSG-GGFVIDAQSRPIDRLCSETLELLLRSTGYNDDI
MUL_3853|M.ulcerans_Agy99 ASTAEFADLAANITSG-GGFVIDAQSRPIDRLCSETLELLLRSTGYNDDI
MAV_1619|M.avium_104 ASTAEFADLAANIVSGQGGFVIESSVRTVDRLCAETLELLLRSTGYSDDV
MSMEG_6131|M.smegmatis_MC2_155 -----------------------HAGRGDERLGESGLLAVAR--------
: : : :
Mflv_4423|M.gilvum_PYR-GCK ALLLYRQ---PEPLDLDFPADVAELAGSRTVLRGWLDSAGVPQDQALDVL
Mvan_3797|M.vanbaalenii_PYR-1 ALLLYRH---PAPLQLNFPADANHLAPARAALRSWLTSARVEPARVMDVL
TH_2781|M.thermoresistible__bu AIVVYRHT--FAPLRIELPATPDRLSEVRARLTGWLTAAGAPELLISDIV
Mb1399c|M.bovis_AF2122/97 TLLAMQRRAPTPPLHITLDATINAARTVRAQLREWLAEIGADHSDIADIV
Rv1364c|M.tuberculosis_H37Rv TLLAMQRRAPTPPLHITLDATINAARTVRAQLREWLAEIGADHSDIADIV
MMAR_3991|M.marinum_M TLLAVQRRAPTPPLNITEDATIHAARAIRSRLRQWLSEIGADSSDISDIV
MUL_3853|M.ulcerans_Agy99 TLLAVQRRAPTPPLNITEDATIHAARAIRSRLRQWLSEIGADSGDISDIV
MAV_1619|M.avium_104 TLLAAQRRTPPPPLNLTLDATIHAARTVRTRLRQWLSDVGADADDISDIV
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------ALAATPGRDFVT
. :
Mflv_4423|M.gilvum_PYR-GCK IAVGEALANAIEHGHRDDPGGRVRLRAVAL-PDRVQLTIIDTGSWKAPDD
Mvan_3797|M.vanbaalenii_PYR-1 VAAGEALANAIEHGHRHTPDGTVSLRATAL-VDRVRLTVADTGSWKVPQP
TH_2781|M.thermoresistible__bu LAVNEACTNSVEHAYRDREPGPMQVYADLR-DGQIMLQVRDFGTWKTPEP
Mb1399c|M.bovis_AF2122/97 HAISEFVENAVEHGYATDVSKGIVVEAALAGDGNVRASVIDRGQWKDHRD
Rv1364c|M.tuberculosis_H37Rv HAISEFVENAVEHGYATDVSKGIVVAAALAGDGNVRASVIDRGQWKDHRD
MMAR_3991|M.marinum_M HAISEFVENAVEHGYSTDVSDGLAVAAALGGDGKLRVAVIDHGTWKHHRE
MUL_3853|M.ulcerans_Agy99 HAISEFVENAVEHGYSTDVSDGLAVAAALGGDGKLRVAVIDHGTWKHHRE
MAV_1619|M.avium_104 HAISEFVENAVEHGYATEVPDGVVVEAMLAGDGNLHASVIDRGRWKDHRE
MSMEG_6131|M.smegmatis_MC2_155 SLINEAESRAQTHGGLSDDIAVIRVERSRR--------------------
.* .: *. : :
Mflv_4423|M.gilvum_PYR-GCK VPALHRGRGIALMKALMQDVTIDSQTTGTTVHMNTRIA------------
Mvan_3797|M.vanbaalenii_PYR-1 GRDSRRGRGIALMRALMHDVEIDIGRSGTSVHLDTRID------------
TH_2781|M.thermoresistible__bu NPRIR-GRGLPMMRAISADVQVDNTRSGTVVELTFTLSGQPALT------
Mb1399c|M.bovis_AF2122/97 G-ARGRGRGLAMAEALVSEARIMHGAGGTTATLTHRLSRPARFVTDTMVR
Rv1364c|M.tuberculosis_H37Rv G-ARGRGRGLAMAEALVSEARIMHGAGGTTATLTHRLSRPARFVTDTMVR
MMAR_3991|M.marinum_M G-ERGRGRGLAMAEALVSETHVSHDGAGTTATVVHRLSRPAQFVTDPVVS
MUL_3853|M.ulcerans_Agy99 G-ERGRGRGLAMAEALVSETHVSHDGAGTTATVVHRLSRPAQFVTDPVVS
MAV_1619|M.avium_104 G-ETGRGRGLAMAEALVSEAHVSHGPEGTTASVTHRLSRPANFVADSLVS
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3797|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 RAAFQQTIDSEFVS-LVESGRIVVRGDVDSTTAATLDRQIAVESRSGIAP
Rv1364c|M.tuberculosis_H37Rv RAAFQQTIDSEFVS-LVESGRIVVRGDVDSTTAATLDRQIAVESRSGIAP
MMAR_3991|M.marinum_M RAPNRPTIDSEFASTVTESGHIVVRGDVDSNTAPTLDRQIAVESRSGIAS
MUL_3853|M.ulcerans_Agy99 RAPNRPAIDSEFASTVTESGHIVVRGDVDSNTAPTLDRQIAVESRSGIAS
MAV_1619|M.avium_104 RAGDHGVRSAEFVSTVTEPGRIVVSGDVDSNTASTLDRQIAVESRSGVAP
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3797|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2781|M.thermoresistible__bu --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 VTIDLSAVTHLGSAGVGALAAACDRARKQGTECVLVAPPGSPAHHVLSLV
Rv1364c|M.tuberculosis_H37Rv VTIDLSAVTHLGSAGVGALAAACDRARKQGTECVLVAPPGSPAHHVLSLV
MMAR_3991|M.marinum_M LTIDLSAVTHLGSAGVSALVTARDRARKQGGRCVLMAPPGSPAHHVLSLV
MUL_3853|M.ulcerans_Agy99 LTIDLSAVTHLGSAGVSALVTARDRARKQGGRCVLMAPPGSPAHHVLSLV
MAV_1619|M.avium_104 LTVDLSAVTHLGSAGVSALAAARERALRQGSDYVLVAPPGSPAHHVLSLV
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK ----------------
Mvan_3797|M.vanbaalenii_PYR-1 ----------------
TH_2781|M.thermoresistible__bu ----------------
Mb1399c|M.bovis_AF2122/97 QLPVVGADTEDIFAQE
Rv1364c|M.tuberculosis_H37Rv QLPVVGADTEDIFAQE
MMAR_3991|M.marinum_M QIPVISGETENVFAED
MUL_3853|M.ulcerans_Agy99 QIPVISGETENVFAED
MAV_1619|M.avium_104 QIPVVSGLAENVVAEG
MSMEG_6131|M.smegmatis_MC2_155 ----------------