For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPTEPVRVSFRRHVREKVLRATRELAIEKGWDQVRMSEVAESVGVSRPTLYKEFGDKQGLGDALVVSEGQ RFMEGILAVLAEHVGDVRGGITAAVQFTLCEAEDSPLLKAVLTSNPSGNDRGGSSSTGVLPLLPTSASLL QLCSAALITWFNDHFDDLDPEDVEEVADVLVRLTVSHVVLPAADIATTGERISRVALRYLGVVHSL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2046 | - | - | 100% (206) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3596c | - | 4e-17 | 28.65% (178) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2152 | - | 2e-09 | 28.72% (188) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 7e-17 | 28.95% (190) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4718 | - | 5e-18 | 28.35% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3249c | - | 8e-17 | 28.95% (190) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 4e-05 | 36.84% (57) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3158 | - | 2e-91 | 82.67% (202) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4212 | - | 4e-17 | 29.47% (190) | putative transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1842 | - | 2e-16 | 26.40% (178) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0467 | - | 2e-18 | 29.21% (178) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2593 | - | 9e-18 | 30.00% (190) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1745 | - | 2e-17 | 28.40% (169) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2046|M.abscessus_ATCC_1997 -------------------------------------------------M
MMAR_3158|M.marinum_M -------------------------------------------------M
Mflv_4718|M.gilvum_PYR-GCK -MTAQPIATSARVATRHADQRRADTRARGASLGPVRATVIVAPVGG-GND
Mvan_1745|M.vanbaalenii_PYR-1 -MRATHRAEPC----RHARSRNTASQGTAVTASAGPGTITVARVGL-SND
TH_0467|M.thermoresistible__bu ---------------------------------------VVSRR-----D
MSMEG_1842|M.smegmatis_MC2_155 MIHAVTHAVAG---------AQFGAPARVVRGPLTAESDIVARVSRPRAK
Mb3277c|M.bovis_AF2122/97 -----------------------------------MSTPSAT----VAPV
Rv3249c|M.tuberculosis_H37Rv -----------------------------------MSTPSAT----VAPV
MUL_2593|M.ulcerans_Agy99 ---------------MPRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPV
MAV_4212|M.avium_104 -------------------------------------------------M
MLBr_00717|M.leprae_Br4923 --------------------------------------------------
MAB_2046|M.abscessus_ATCC_1997 PTEPVRVSFRRHVREKVLRATRELAIEKGWDQVRMSEVAESVGVSRPTLY
MMAR_3158|M.marinum_M PTDSARMSFRRHIREQVLRATRELTIEKGWEQVRVSEVAELVGVSRPTLY
Mflv_4718|M.gilvum_PYR-GCK KRISYAEASRVLLRDSILDGMREMLLARDWSQITLSDVAKAAGISRQTIY
Mvan_1745|M.vanbaalenii_PYR-1 KRVSYAEASRVLLRDSILDGMREMLLTRDWSAITLSDVAKAAGISRQTIY
TH_0467|M.thermoresistible__bu KRVPYAEASRVLLRDSILDGMRELLQTRDWSQITLADVAKAAGISRQTIY
MSMEG_1842|M.smegmatis_MC2_155 QRMPYAEASRVLLRDSILDGMRDLLLTRDWSAITLSHVAQAAGVSRQTIY
Mb3277c|M.bovis_AF2122/97 KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
Rv3249c|M.tuberculosis_H37Rv KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
MUL_2593|M.ulcerans_Agy99 KRVPYAEASRVLLRDSVLDAMRDLLFTRDWSAITLSDVARSAGISRQTIY
MAV_4212|M.avium_104 KRMPYAEASRALLRDSVLDAMRDLLVTRDWSAITLSDVARAAGISRQTIY
MLBr_00717|M.leprae_Br4923 MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMY
. * .:* :: : :. : : .:*. .*:** :*
MAB_2046|M.abscessus_ATCC_1997 KEFGDKQGLGDALVVSEGQRFMEGILAVLAEHVGDVRGGITAAVQFTLCE
MMAR_3158|M.marinum_M KEFGDKQGLGDALVVAEGQRFLEGIHAILAEHTGDVQGGITAAVRFTLRE
Mflv_4718|M.gilvum_PYR-GCK NEFGSRQGLAQGYAMRLADRLVDQIHAAIDNNVGDMYAAFLQGFRDFFVE
Mvan_1745|M.vanbaalenii_PYR-1 NEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRDFFVE
TH_0467|M.thermoresistible__bu NEFGSRQGLAQGYALRLADRLVDEVDEAIANNVGDIHAAFLAGFRKFFAE
MSMEG_1842|M.smegmatis_MC2_155 NEFGSRQGLAEGYAMRLADRLVDAVDDAINNNVGDVYAAFLEGFRAFFAE
Mb3277c|M.bovis_AF2122/97 NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
Rv3249c|M.tuberculosis_H37Rv NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
MUL_2593|M.ulcerans_Agy99 NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MAV_4212|M.avium_104 NEFGSRQGLAQGYALRLADRLVDTIHEALDAHVGNIYESFLDAFRRFFAD
MLBr_00717|M.leprae_Br4923 HYFPDKRAFFAAVVKDEADRLYAATNIPPPAGL-TMFEEVRVGVLAYMAY
: * .::.: . . .:*: . . .. :
MAB_2046|M.abscessus_ATCC_1997 AEDSPLLKAVLTSNPSGNDRGGSSSTGVLPLLPT-SASLLQLCSAALITW
MMAR_3158|M.marinum_M AEASPLLKSVLTSSHSGDDRAGAPTTGVLPLLPT-SASLLQLSSAALVAW
Mflv_4718|M.gilvum_PYR-GCK SAADPLVISLLT---------GSSKPDLLQLITTDSAPIINHCSSRLTES
Mvan_1745|M.vanbaalenii_PYR-1 SAADPLVISLLT---------GTSKPDLLQLITTDSAPIINHCSSRLTES
TH_0467|M.thermoresistible__bu SAADPLVISLLT---------GSAKPDLLQLITTDSAPIITRASQRLTES
MSMEG_1842|M.smegmatis_MC2_155 SAADPLVISLLT---------GAAKPDLLQIITIGSGPIITRCSERLTAT
Mb3277c|M.bovis_AF2122/97 SAADPLVISLLT---------GVAKPDLLQLITTDSAPIITRASARLAPA
Rv3249c|M.tuberculosis_H37Rv SAADPLVISLLT---------GVAKPDLLQLITTDSAPIITRASARLAPA
MUL_2593|M.ulcerans_Agy99 SAADPLVISLLT---------GVAKPDLLQLITTDSAPIITRASARLATA
MAV_4212|M.avium_104 AAADPLVTSLRT---------GVAKPDLLQLITTDSAVIITRASARLASA
MLBr_00717|M.leprae_Br4923 HKQNPEAAWAAYVG------LGRSDPVLLGIDDEAKNRQMEHIMSRIGDV
.* * . . :* : . : :
MAB_2046|M.abscessus_ATCC_1997 FNDHFDDLDPEDVEEVADVLVR--------LTVSHVVLP---AADIATTG
MMAR_3158|M.marinum_M FHDHFADLDSEDVEEVADVLVR--------LTVSHVVLP---SADIATTG
Mflv_4718|M.gilvum_PYR-GCK LMGSWVRCSEEDAGVLSRAIVR--------LAMSYISMPPEADHDVARDL
Mvan_1745|M.vanbaalenii_PYR-1 FMSSWVRVSQEDAGVLARAIVR--------LAMSYISMPPEADHDVARDL
TH_0467|M.thermoresistible__bu FQSSWVRASEEDAGVLARAIVR--------LAMSYVSMPPEADHDVAHDL
MSMEG_1842|M.smegmatis_MC2_155 FQSSWIKASDDDAGVLARAIVR--------LAMSYVSMPPEADHDVAGDL
Mb3277c|M.bovis_AF2122/97 FTDTWVATTDNDANVLSRAIVR--------LCLSYVSMPPEADHDVAADL
Rv3249c|M.tuberculosis_H37Rv FTDTWVATTDNDANVLSRAIVR--------LCLSYVSMPPEADHDVAADL
MUL_2593|M.ulcerans_Agy99 FTQTWVATSDDDANVLARAIVR--------LSLSYVSMPPEADHNVAADL
MAV_4212|M.avium_104 LTHTWVSTTDEDAGVLARAIVR--------LALSYVSMPPEADHDVAADL
MLBr_00717|M.leprae_Br4923 VSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRLADSC
. * .:*: : . : * :*
MAB_2046|M.abscessus_ATCC_1997 ERISRVALRYLGVVHSL-------------
MMAR_3158|M.marinum_M ARISRVALRYLGVGYR--------------
Mflv_4718|M.gilvum_PYR-GCK ARLMTPFAERYGVVADPVEGGNSQVTRRP-
Mvan_1745|M.vanbaalenii_PYR-1 ARLMTPFAERYGVIDP--------------
TH_0467|M.thermoresistible__bu ARLMTPFAERYGVIEEV-------------
MSMEG_1842|M.smegmatis_MC2_155 ARLMSPFAERYGVIDTP-------------
Mb3277c|M.bovis_AF2122/97 ARLITPFAERHGVINVP-------------
Rv3249c|M.tuberculosis_H37Rv ARLITPFAERHGVINVP-------------
MUL_2593|M.ulcerans_Agy99 ARLMTPFAERHGVINVP-------------
MAV_4212|M.avium_104 ARLMTPFAERHGVVNVG-------------
MLBr_00717|M.leprae_Br4923 AHALLDAIARVPEISKELADAMAIARQPPQ
: