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AYSAFVRTHGWSGAKPASDDEAVARILEAAGKAIEERGADFSISDVARTVGVTRQTVYRYFSSTEALLVA AAVHAVDGFLDRLAAHLVGVTDPPEAVTEAVATALEWLPREKYIGLIMAPGGSTHVQSVTSDIALRFARD MVGRLDVDWTAAGFDEAELDQLSEHLLRIIQSFVLDPGRPPRRGDELRSYLRRWVGNALLRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1606 | - | - | 100% (203) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4281 | - | 1e-47 | 45.92% (196) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0364 | - | 3e-46 | 47.45% (196) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 2e-06 | 40.00% (75) | transcriptional regulatory repressor protein (TETR-family) |
| M. tuberculosis H37Rv | Rv1255c | - | 2e-06 | 25.45% (165) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 3e-05 | 30.33% (122) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4765 | - | 2e-45 | 47.18% (195) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 1e-44 | 46.94% (196) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_1115 | - | 8e-57 | 56.41% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5854 | - | 3e-80 | 71.28% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1262 | - | 3e-77 | 69.23% (195) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 1e-36 | 45.61% (171) | hypothetical protein MUL_4888 |
| M. vanbaalenii PYR-1 | Mvan_5152 | - | 1e-100 | 88.00% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1606|M.gilvum_PYR-GCK ---MAYSAFVRTHGWSGAKPASDDEAVARILEAAGKAIEE-RGADFSISD
Mvan_5152|M.vanbaalenii_PYR-1 MTGLAYSSLVRTHGWSGAKPASDEEAVARILAAAGKVIEE-RGADFSISD
MSMEG_5854|M.smegmatis_MC2_155 ---------MRTHGWSGSAPATDEEAIARILAAAGKAIDE-RGADFSIAD
TH_1262|M.thermoresistible__bu ---------MRTHGWGGSAPASDEEAIARILEAAKRTIEE-RGAEFSIAD
MAV_1115|M.avium_104 ---------MRRHGWSGDIPADDEEAVARILTATRRAIDE-RGT-VSVSQ
MMAR_0226|M.marinum_M --------MARRRGWNGAPPASDEEASRRIVDTAVRLIAE-TGSDVSLAQ
MUL_4888|M.ulcerans_Agy99 --------MVSRPKRRGVSRIG------RGVRRHRRGIAE-TGSDVSLAQ
MAB_4765|M.abscessus_ATCC_1997 --------MARRRGWDGQPPSSDEEAAERIVAAAVKLIGE-TGSAVSLAD
Rv1255c|M.tuberculosis_H37Rv ---------MAGTDWLS--ARRTELAADRILDAAERLFTQRDPASIGMNE
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFAT-EGLSVPIDE
Mb3885|M.bovis_AF2122/97 -MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDD
: . : . : :
Mflv_1606|M.gilvum_PYR-GCK VARTVGVTRQTVYRYFSSTEALLVAAAVHAVDGFLDRLAAHLVGVTDP--
Mvan_5152|M.vanbaalenii_PYR-1 VARTVGVTRQTVYRYFPSTEALLVAAAVHAVDGFLERLTAHMAGITDP--
MSMEG_5854|M.smegmatis_MC2_155 VARTLGVTRQTVYRYFPSTDALLVAAAVHAASGFLDRLAAHLSGITDP--
TH_1262|M.thermoresistible__bu VARAVGVTRQTVYRYFPSTDALLVAAAMHAAGDFLDRLAVHLQGITDP--
MAV_1115|M.avium_104 VASTLGVTRQTIYRYFPTHEALLGATALSAVEGFLDRLAAHLGSITDP--
MMAR_0226|M.marinum_M VAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLTEAVRGMRDP--
MUL_4888|M.ulcerans_Agy99 VAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLTEAVRGMRDP--
MAB_4765|M.abscessus_ATCC_1997 VAAELGVIRQTVYRYFPTADALMHAASLASVDGFLDRLTHVVRGITDP--
Rv1255c|M.tuberculosis_H37Rv IAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEP--
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPG--
Mb3885|M.bovis_AF2122/97 LAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDR
:* * *.* :: : :*: : .
Mflv_1606|M.gilvum_PYR-GCK PEAVTEAVATALEWLPREK-YIGLIMAPGG-STHVQSVT-SDIALRFARD
Mvan_5152|M.vanbaalenii_PYR-1 AEAVTEAVATALEWLPREK-YIGLIMVPGR-STHVQSVT-SDIALRFGRD
MSMEG_5854|M.smegmatis_MC2_155 VEAVTEAIATALEWVPQDK-HLGLLISPGRADAHTESVT-SDVAVDFARA
TH_1262|M.thermoresistible__bu VEAVAEAIATTLEWLPEDT-HIGLLVAPGRPTAHTESVT-SDVAIDFANR
MAV_1115|M.avium_104 TEAVVEGIAYTFEQLAHDR-YLSLVFQPGKASAFTAGVT-SDIAISFGRS
MMAR_0226|M.marinum_M AEAMAEAVMFTLRDVVRTP-HLGILIAQPYAHTHPENLT-SEEAQVFGVR
MUL_4888|M.ulcerans_Agy99 AEAMAEAVMFTLRDVVRTP-HLGILIAQPYAHTHPENLT-SEEAQVFGVR
MAB_4765|M.abscessus_ATCC_1997 AEALTEGVLYTLEEVTRTP-HLGIMMSEPYAHSHTSDMT-SDEAQAFGLR
Rv1255c|M.tuberculosis_H37Rv AERLLVSITTTLRMVRDNP-ALAAWFTTTRPPIGGEMAGRSEVIAALAAA
MLBr_00316|M.leprae_Br4923 EALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAEDAFLTILSD
Mb3885|M.bovis_AF2122/97 ENMWRTGINVFFETFGSHK-AVTRAGQAARATSVEVAELWSTFMQKWIAY
:. : .
Mflv_1606|M.gilvum_PYR-GCK MVGRLDVDWTAAGF-DEAELDQLSEHLLRIIQSFVLD--PGR-PPRRGDE
Mvan_5152|M.vanbaalenii_PYR-1 MVGRLDVDWAAAGF-DDADLDQLSEHLLRIIQSFVVD--PGR-PPRHGEQ
MSMEG_5854|M.smegmatis_MC2_155 MLRKFDVDWAGLGF-GDDDLDELAEHLLRIIQSFIID--PGR-PPRTGAT
TH_1262|M.thermoresistible__bu MLRRFDVDWAAVGY-SDADLDELAEHLLRVIQSFVID--PGR-PPRDGQS
MAV_1115|M.avium_104 ILQRFEVDWGAAGF-ADAGLDELVEVMLRTLQSLIVD--PGR-PPRTGAE
MMAR_0226|M.marinum_M MLERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVA--PNV-PSRSDDE
MUL_4888|M.ulcerans_Agy99 MLERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVA--PNV-PSRSDDE
MAB_4765|M.abscessus_ATCC_1997 MLDRFDVDWVQYGY-DDAAKRELVEFALRIMLSFFVS--PNE-ATRSRDE
Rv1255c|M.tuberculosis_H37Rv FLNSLGPD-------DPTTVERRARWVVRMLTSLLMF--PGRDEADERAM
MLBr_00316|M.leprae_Br4923 LL-----------YAAQYAGTARTDVGVREVKSILVG--CQAMEAYN-SA
Mb3885|M.bovis_AF2122/97 TAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEAR
.. .
Mflv_1606|M.gilvum_PYR-GCK LRSYLRRWVGNALLRR---------
Mvan_5152|M.vanbaalenii_PYR-1 LRTYLRRWVGNALPLR---------
MSMEG_5854|M.smegmatis_MC2_155 LRSYLRRWVGAAVKPAQASVQSPRV
TH_1262|M.thermoresistible__bu LRAYLRRWVGAAVTGAR--------
MAV_1115|M.avium_104 LRRFLQDWVAPAVRAHAISR-----
MMAR_0226|M.marinum_M LKSFIKRWVGGAILAQKR-------
MUL_4888|M.ulcerans_Agy99 LKSFIRRWVGGAIVAQKR-------
MAB_4765|M.abscessus_ATCC_1997 LRGFLKRWLGGAVLAQGR-------
Rv1255c|M.tuberculosis_H37Rv IAEFVVPIVTPASAAARKAGHPGPE
MLBr_00316|M.leprae_Br4923 LAERVTDVVVDGLRAAR--------
Mb3885|M.bovis_AF2122/97 VLDTLVHIWVTSIYGENR-------
: : .