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VLQSTSITKSPRRIDSKERRLFHPSFRRNGVRRLSCVARTRTSLTHWGAFSATVESGDIASVRPWSGDAD PSPALGNLPGSVRHRSRVTAPAVRRGWLENGPGPDTLLGADEFVAVTWDDLVELLGGELRRVIDTHGNEA IYGGSYGWSSAGRFHHAQSQVHRFLNCLGGYTYSRHSYSLGATGVIMPRVVGTHDDLFTRSTQWQVIVEN TDTMVCFGGLALKNTAVNDGGTTAHPARDALNRLRARGGRIVSFSPLRDDVDGPCDWHAPVPGTDVAIML ALAHVLATESLADREFLASHCTGYDRFERYLLGADDGIPKSPQWASSLCGLSADDLTALARRMAAGRTLV TVSWSLQRTRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEAGLAPIRCGLPRLPQGVNPVTTFIP VAAVSDMLLHPGEPFDYNGLRLTYPDIRLVYWAGGNPFHHHQNLPRLRRALSRPDTVVVHDPYWTAMAKH ADIVVPSTTFAERDDLSGSRNDPMLMAMPRLTETYAQARDDYDTYAALAGHLGVRQAFTEGRSSRQWLRH IYETWSRTLDFDVPAFDGFWAAGALRLPTDDGLTLLADFRADPSAHPLATPSGRIEIFSADIDSFGYDDC RGHPAWFEPTEWLGGPRAADYPLHLVANQPAGRLHGQLDAGAASQATKVAGREPIRMHPADAHARDLSGG DVVRVFNDRGACLAGVVLDDRVRPQVVQLSTGAWFDPADPADPHSMCVHGNPNVLTDDVGTSKLAHGCTG AHVLVQIEKYAGTPPPVRAHQPPVFTPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3958 | - | - | 100% (798) | molybdopterin guanine dinucleotide-containing S/N-oxide reductase |
| M. gilvum PYR-GCK | Mflv_5161 | - | 2e-32 | 24.50% (694) | molybdopterin oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4342 | - | 8e-22 | 25.58% (477) | molydopterin dinucleotide-binding region |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1477 | bisC | 0.0 | 68.16% (760) | biotin sulfoxide reductase |
| M. tuberculosis H37Rv | Rv1442 | bisC | 0.0 | 68.16% (760) | biotin sulfoxide reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3041 | - | 0.0 | 73.61% (758) | putative biotin sulfoxide reductase BisC |
| M. marinum M | MMAR_3639 | fdhF | 9e-17 | 21.90% (653) | formate dehydrogenase H FdhF |
| M. avium 104 | MAV_4535 | - | 4e-20 | 23.43% (478) | nitrate reductase NarB |
| M. smegmatis MC2 155 | MSMEG_2738 | - | 0.0 | 77.69% (753) | biotin sulfoxide reductase |
| M. thermoresistible (build 8) | TH_4041 | - | 3e-25 | 26.71% (513) | PUTATIVE Formate dehydrogenase |
| M. ulcerans Agy99 | MUL_1474 | fdhF | 6e-17 | 21.90% (653) | formate dehydrogenase H FdhF |
| M. vanbaalenii PYR-1 | Mvan_2438 | - | 0.0 | 84.60% (766) | molybdopterin guanine dinucleotide-containing S/N-oxide |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1477|M.bovis_AF2122/97 -------------------------------------MQVYTSATHWGVF
Rv1442|M.tuberculosis_H37Rv -------------------------------------MQVYTSATHWGVF
Mflv_3958|M.gilvum_PYR-GCK MLQSTSITKSPRRIDSKERRLFHPSFRRNGVRRLSCVARTRTSLTHWGAF
Mvan_2438|M.vanbaalenii_PYR-1 MVG-----------------------RGGRAVRLSSVSATQTSLTHWGAF
MSMEG_2738|M.smegmatis_MC2_155 ------------------------------------MPHSPTSLTHWGVF
MAB_3041|M.abscessus_ATCC_1997 -------------------------MIRPAFSAVQVSGSARLSHTHWGAF
MMAR_3639|M.marinum_M -----------------------------MAPNKDAVKTVCAYCGVGCGI
MUL_1474|M.ulcerans_Agy99 -----------------------------MAPNKDAVKTVCAYCGVGCGI
MAV_4535|M.avium_104 -----------------MATDRIANPWGTRTPYAPGTRWPERIDTYLADG
TH_4041|M.thermoresistible__bu -------------------------------MATEQRVTYCRICEPLCGL
Mb1477|M.bovis_AF2122/97 TARVHGGDIAAVAALASDTNPAPQLQNLPGAVRHRSRIANPAVRRGWLQH
Rv1442|M.tuberculosis_H37Rv TARVHGGDIAAVAALASDTNPAPQLQNLPGAVRHRSRIANPAVRRGWLQH
Mflv_3958|M.gilvum_PYR-GCK SATVESGDIASVRPWSGDADPSPALGNLPGSVRHRSRVTAPAVRRGWLEN
Mvan_2438|M.vanbaalenii_PYR-1 SATVEAGEITAVAPVAGDDDPSVALGNLPGSVRHISRVTTPAVRRGWLDH
MSMEG_2738|M.smegmatis_MC2_155 SAEIVDGDIAAVNPPPDDADPSPLLGNMPGSIRHRARITGPAVRRGWLRD
MAB_3041|M.abscessus_ATCC_1997 TPEVRDGEVIGVTPIETDLDPSPLLQNIPGSIRHQARVTAPAVRSGWLRE
MMAR_3639|M.marinum_M VLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLLAAPGRMES
MUL_1474|M.ulcerans_Agy99 VLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLLAAPGRMES
MAV_4535|M.avium_104 VTAESVDRWVQSAAVLHSNGDGLDIAVKDGRIVGVRGRAVDRVNHGRLDP
TH_4041|M.thermoresistible__bu IATVEDGRLQSLRP------DPDHPLSRGRACPKGIAFTEVQNDPDRVLY
. : . :
Mb1477|M.bovis_AF2122/97 G-------------PGPSSARGAEEFVEVSWDELIELLASELRRTVDRYG
Rv1442|M.tuberculosis_H37Rv G-------------PGPSSARGAEEFVEVSWDELIELLASELRRTVDRYG
Mflv_3958|M.gilvum_PYR-GCK G-------------PGPDTLLGADEFVAVTWDDLVELLGGELRRVIDTHG
Mvan_2438|M.vanbaalenii_PYR-1 G-------------PGPDDSRGADDFVAVTWDELTELLGDELRRVIDTHG
MSMEG_2738|M.smegmatis_MC2_155 G-------------PGPSTERGADEFVAVSWDELTDLLATELRRVVDTYG
MAB_3041|M.abscessus_ATCC_1997 G-------------PGPSDKRGADEYVEVSWDELTELLADELRRVVDTHG
MMAR_3639|M.marinum_M ---------------AHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHG
MUL_1474|M.ulcerans_Agy99 ---------------AHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHG
MAV_4535|M.avium_104 KDLFGWQANASADRLTTPLLRVRGALRPCDWDTAMERIVARSRELLDRHG
TH_4041|M.thermoresistible__bu P----------------LRRRADGEFERVGWDEALDDIAARLTAIRDRHG
* . * :*
Mb1477|M.bovis_AF2122/97 NEAIYGSSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIF
Rv1442|M.tuberculosis_H37Rv NEAIYGSSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIF
Mflv_3958|M.gilvum_PYR-GCK NEAIYGGSYGWSSAGRFHHAQSQVHRFLNCLGGYTYSRHSYSLGATGVIM
Mvan_2438|M.vanbaalenii_PYR-1 NGAIYGGSYGWSSAGRFHHAQSQVHRFLNCLGGYTFSRHSYSLGATGVIM
MSMEG_2738|M.smegmatis_MC2_155 NEAIYGGSYGWSSAGRFHHAQSQVHRFLKMLGGYTFSRHSYSLGATGAIM
MAB_3041|M.abscessus_ATCC_1997 NEAIYGGSYGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGVIM
MMAR_3639|M.marinum_M PDAVGVYVSGQMSIEAQYLANKLTKGFIGTNQIESNSRLCMAGASSGYKL
MUL_1474|M.ulcerans_Agy99 PDAVGVYVSGQMSIEAQYLANKLTKGFIGTKQIESNSRLCMAGASSGYKL
MAV_4535|M.avium_104 PSSIGFYTSGQLFAEEYYTQAAIAHGAIGTNHVDGNTRLCTATAAEALKE
TH_4041|M.thermoresistible__bu GGAIGQYFGNPVAFG--YATALWSGMFVARLG----SRHQYSSGSQDINS
:: . : : :* : .:
Mb1477|M.bovis_AF2122/97 PHIVGAALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHP
Rv1442|M.tuberculosis_H37Rv PHIVGAALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHP
Mflv_3958|M.gilvum_PYR-GCK PRVVG-THDDLFTRSTQWQVIVENTDTMVCFGGLALKNTAVNDGGTTAHP
Mvan_2438|M.vanbaalenii_PYR-1 PRVVG-THDDLFKRSTQWDVIVEHTDLMVCFGGVALKNTGVNHGGTTAHP
MSMEG_2738|M.smegmatis_MC2_155 PRVVG-THDDLFKRSTQWDVIVEHTGLMVCFGGMPLKNTGINDGGTSAHP
MAB_3041|M.abscessus_ATCC_1997 PHVIG-THDGLFKRSTSWDVIVENTDLLIAFGGIALKNTGVNHGGTTAHP
MMAR_3639|M.marinum_M SLGAD--------GPPGSYQDFDHADVFLVIG--------ANMADCHPIL
MUL_1474|M.ulcerans_Agy99 SLGAD--------GPPGSYQDFDHADVFLVIG--------ANMADCHPIL
MAV_4535|M.avium_104 SFGCD--------GQPGSYTDVDHADVIALFG--------HNVAETQTVL
TH_4041|M.thermoresistible__bu RFVAS--KLLYGAASQIPFPDLPRTDFLFMLG---ANPFVSHGSALRAPR
. . .: : :* . .
Mb1477|M.bovis_AF2122/97 DRDYVGRYRARGGRLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIM
Rv1442|M.tuberculosis_H37Rv DRDYVGRYRARGGRLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIM
Mflv_3958|M.gilvum_PYR-GCK ARDALNRLRARGGRIVSFSPLRDDV-------DGPCDWHAPVPGTDVAIM
Mvan_2438|M.vanbaalenii_PYR-1 ARGALDRFRARGGHLVSFSPLRDDV-------DGPCDWFAPVPGTDVAIM
MSMEG_2738|M.smegmatis_MC2_155 MRDALRRFRGRGGRIVSFSPLRDDV-------DGDCQWLALRPGTDVAVM
MAB_3041|M.abscessus_ATCC_1997 ARDALNRFRDRGGRIVSFSPLHDDI-------DGECEWHAPIPGTDVAVM
MMAR_3639|M.marinum_M FLRMMERVKS-GAKLIVVDPRRTAT------ADKADLFLQIAPGTDLALL
MUL_1474|M.ulcerans_Agy99 FLRMMERVKS-GAKLIVVDPRRTAT------ADKADLFLQIAPGTDLALL
MAV_4535|M.avium_104 WARMLDRLAGSDPPAIVCVDPRLTP-----VARHATVHLAPLPGTNVALM
TH_4041|M.thermoresistible__bu IKDDLTDITRRGGRVVVVDPRRTET-------ARAFEHIAVRPDSDAWLL
: . : : *.:: ::
Mb1477|M.bovis_AF2122/97 LGLAYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALS
Rv1442|M.tuberculosis_H37Rv LGLAYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALS
Mflv_3958|M.gilvum_PYR-GCK LALAHVLATESLADREFLASHCTGYDRFERYLLGADDGIPKSPQWASSLC
Mvan_2438|M.vanbaalenii_PYR-1 LALAHVLAAESLADRDFLATYCTGYDRFERYLLGVDDGTPKSPQWAAQIC
MSMEG_2738|M.smegmatis_MC2_155 LGLAYVLATEGLADREFLDTHCTGYERFERYLLGHDDGVAKSPEWAAHIS
MAB_3041|M.abscessus_ATCC_1997 LALAHVLAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPKSPEWAAPIS
MMAR_3639|M.marinum_M NGLLHLIVENEQTDPQFISEFTEGWEVMPSFLEQFT------PDRVSEIT
MUL_1474|M.ulcerans_Agy99 NGLLHLIVENEQTDPQFISEFTEGWEVMPSFLEQFT------PDRVSEIT
MAV_4535|M.avium_104 NGLLHEIIGNGWIDRDYIDAHSVGFDELQCRVSEFT------PEWVAEIC
TH_4041|M.thermoresistible__bu LSMLQVIFAEGLEDTAAIARQTTGCSTLRGLVAGFP------PEATAART
.: : : * : * . : : *: .:
Mb1477|M.bovis_AF2122/97 GLAAGDLRDLARRMAEHR-TLITTSLSLQRIEHGEQTVWMAATLAAMLGQ
Rv1442|M.tuberculosis_H37Rv GLAAGDLRDLARRMAEHR-TLITTSLSLQRIEHGEQTVWMAATLAAMLGQ
Mflv_3958|M.gilvum_PYR-GCK GLSADDLTALARRMAAGR-TLVTVSWSLQRTRHGEQAPWMGLTLAAMLGQ
Mvan_2438|M.vanbaalenii_PYR-1 GLDADDLTALARRMAACR-TIVTVSWSLQRTRHGEQAPWMGLTLAAMLGQ
MSMEG_2738|M.smegmatis_MC2_155 GLSADTLRALAHRMAAER-TIVTVSWSLQRTRHGEQAPWMGVTLAAMLGQ
MAB_3041|M.abscessus_ATCC_1997 GLDAAELRTLARRMAAGR-TLVTVSWSLQRVRHGEQAPWMGLTLAAMLGQ
MMAR_3639|M.marinum_M GIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGTWNTNALCNLHLATGA
MUL_1474|M.ulcerans_Agy99 GIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGTWNTNALCNLHLATGA
MAV_4535|M.avium_104 GVAATDLRRAARLIGTAQRLLSTVLQGFYQSHQATAAAVQVNNIHLVRGM
TH_4041|M.thermoresistible__bu GVPADVVRSLARDFAAAPTAAAYGRTGACLGRHGTLVSFLLDALSIVTGN
*: : : *: :. . :. : *
Mb1477|M.bovis_AF2122/97 IGLPG----GGFGHGY-SSNGVGNPPLACGLPALPQGNNPVSTFIPVAAI
Rv1442|M.tuberculosis_H37Rv IGLPG----GGFGHGY-SSNGVGNPPLACGLPALPQGNNPVSTFIPVAAI
Mflv_3958|M.gilvum_PYR-GCK IGLPG----GGFGHGYGSMNEAGLAPIRCGLPRLPQGVNPVTTFIPVAAV
Mvan_2438|M.vanbaalenii_PYR-1 IGLPG----GGFGHGYGSMNEPGLAPVRCGLPRLPQGINPVTTFIPVAAV
MSMEG_2738|M.smegmatis_MC2_155 IGLPG----GGFGHGYGSMNEPGLAPLRCRLPSLPQGPNPVRTFIPVAAV
MAB_3041|M.abscessus_ATCC_1997 IGLPG----GGFGHGYGSMNEPGLAPVSCPLPTFPQGPNPVETFIPVAAI
MMAR_3639|M.marinum_M ICRPG----SGPFSLTGQPNAMGGREMGYMGPGLP-GQRSVLSAPDREFV
MUL_1474|M.ulcerans_Agy99 ICRPG----SGPFSLTGQPNAMGGREMGYMGPGLP-GQRSVLSAPDREFV
MAV_4535|M.avium_104 LGRPG----CGVLQMNGQPTAENTR--ECGADGDLAGFRNWSNDSHVAEL
TH_4041|M.thermoresistible__bu LDREGGLLMAHAVIPFEELGERTGRLTYGTERSRIGGLPEVISTFPAALM
: * . * . :
Mb1477|M.bovis_AF2122/97 SELLQRPGQRLAYNG--------RLLELP-DIKCVYWAGGNPFHHHQNLP
Rv1442|M.tuberculosis_H37Rv SELLQRPGQRLAYNG--------RLLELP-DIKCVYWAGGNPFHHHQNLP
Mflv_3958|M.gilvum_PYR-GCK SDMLLHPGEPFDYNG--------LRLTYP-DIRLVYWAGGNPFHHHQNLP
Mvan_2438|M.vanbaalenii_PYR-1 SDMLLSPGEPFDYNG--------LRLHYP-DIRLVYWAGGNPFHHHQNIP
MSMEG_2738|M.smegmatis_MC2_155 TDMLLHPGEPFDYNG--------LRLTYP-DIKCVYWSGGNPFHHHQNIP
MAB_3041|M.abscessus_ATCC_1997 SELLLRPGQTLAYNG--------QTLTLP-DIRCVYWAGGNPFHHHQNLP
MMAR_3639|M.marinum_M EEQWGLPGGALRTDVSGGVIDMFSRMADG-EIKACWIICSNPVATVANRK
MUL_1474|M.ulcerans_Agy99 EEQWGLPGGALRTDVSGGVIDMFSRMADG-EIKACWIICSNPVATVANRK
MAV_4535|M.avium_104 ADLWNLEPLQIPHYGPPTHAMQMFRFAEEGTLRMLWVTATNPAVSLPELP
TH_4041|M.thermoresistible__bu ADEINTPG--------------------DGQLRALFVTAGNPVLTVPNGP
: :: : ** :
Mb1477|M.bovis_AF2122/97 RLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDF----AASKT
Rv1442|M.tuberculosis_H37Rv RLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDF----AASKT
Mflv_3958|M.gilvum_PYR-GCK RLRRALSRPDTVVVHDPYWTAMAKHADIVVPSTTFAERDDL----SGSRN
Mvan_2438|M.vanbaalenii_PYR-1 RLRRALRRPDTVVVHDPYWTPMAKHADIVVPSTTFAERHDF----SGSRN
MSMEG_2738|M.smegmatis_MC2_155 RLRRALGRVDTIVVHDPYWTAMAKHADIVVPSTTSFERNDF----SGSKN
MAB_3041|M.abscessus_ATCC_1997 RLRRALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDDF----SGSRN
MMAR_3639|M.marinum_M TVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDG----VMVNC
MUL_1474|M.ulcerans_Agy99 TVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDG----VMVNC
MAV_4535|M.avium_104 RIRDILSQQRLFLVVQDIFLTETAALADVVLPAAAWAEKTG----TFTNA
TH_4041|M.thermoresistible__bu ALEKVLGKLDLIVSLDFYVTETNRHAHYVLPATTFLERDDYPYGFAANCP
: * : .: : *: .:: .
Mb1477|M.bovis_AF2122/97 NPTLIAMPAMVPPYANARDDYHTFSALAHRLGFG----KQFTEGRSAREW
Rv1442|M.tuberculosis_H37Rv NPTLIAMPAMVPPYANARDDYHTFSALAHRLGFG----KQFTEGRSAREW
Mflv_3958|M.gilvum_PYR-GCK DPMLMAMPRLTETYAQARDDYDTYAALAGHLGVR----QAFTEGRSSRQW
Mvan_2438|M.vanbaalenii_PYR-1 DPVLMAMRRLAEPYAQARDDYDTFAALARRLGVA----DTFTEGRTSAQW
MSMEG_2738|M.smegmatis_MC2_155 DPLLVAMPQLAEPYADSRDDYTTFSALAERLGFG----EQFTEGRTAWEW
MAB_3041|M.abscessus_ATCC_1997 DPLLVAMKAVAPPYANSRDDYTTFSALADRLGFG----EQFSEGRTAAQW
MMAR_3639|M.marinum_M ERNMSLFPKAVDPVGDALPDWQIIARIACEMGFS----ESFSYSSAAEVF
MUL_1474|M.ulcerans_Agy99 ERNMSLFPKAVDPVGDALPDWQIIARIACEMGFS----ESFSYSSAAEVF
MAV_4535|M.avium_104 DRTVHLSEKAVEPPGSARSDLEIFLDYARRMDFRDKDGRPFPPWTDPESA
TH_4041|M.thermoresistible__bu TVFIQSAEPVVGAYGEARNEWEVFDELARRMGLS-----LFATGPLERLN
: . . ..: : * .:.. *.
Mb1477|M.bovis_AF2122/97 LEH-MYDKWSAELDFPVPSFAEFW-------RTG-RLELP---TRTGLTW
Rv1442|M.tuberculosis_H37Rv LEH-MYDKWSAELDFPVPSFAEFW-------RTG-RLELP---TRTGLTW
Mflv_3958|M.gilvum_PYR-GCK LRH-IYETWSRTLDFDVPAFDGFW-------AAG-ALRLP---TDDGLTL
Mvan_2438|M.vanbaalenii_PYR-1 LRH-LYEKWSATLDFEVPSFDEFW-------QVG-QVRLP---TDEGLTL
MSMEG_2738|M.smegmatis_MC2_155 LVH-LYEKWAAGLDFAVPSFAEFW-------AAG-HVELP---TDTGLTL
MAB_3041|M.abscessus_ATCC_1997 LRH-IYTEWAGALNFSVPSFDEFW-------DRG-YLELP---TDAGLTL
MMAR_3639|M.marinum_M EEIKRFSNPATGYDLRGISHDRLR-------ETP-LQWPC---PPDGASN
MUL_1474|M.ulcerans_Agy99 EEIKRFSNPATGYDLRGISHDRLR-------ETP-LQWPC---PPDGASN
MAV_4535|M.avium_104 FEAWKKCSAGRPCDYTGLSYAKLR-------GGSGIQWPCNTDHPDGIER
TH_4041|M.thermoresistible__bu PVLAWLDRRGVGRLTPRRLMELLLRLGPYGDRFG---------LRRGGLN
. : *
Mb1477|M.bovis_AF2122/97 LADFRADPAAHPLGTPSGRIEIFSDTVDAFALP--DCAGHPTWYEPSEWL
Rv1442|M.tuberculosis_H37Rv LADFRADPAAHPLGTPSGRIEIFSDTVDAFALP--DCAGHPTWYEPSEWL
Mflv_3958|M.gilvum_PYR-GCK LADFRADPSAHPLATPSGRIEIFSADIDSFGYD--DCRGHPAWFEPTEWL
Mvan_2438|M.vanbaalenii_PYR-1 FADFRADPSAHRLATPSGRIEIFSADIAGFGYR--DCVGHPAWFEPAEWL
MSMEG_2738|M.smegmatis_MC2_155 FEDFRADPQAHPLGTPSGRIEIFSEDIDSFGYD--DCAGHPRWYEPAEWL
MAB_3041|M.abscessus_ATCC_1997 LSDFRENPAAHPLHTPSGRIEIFSETIDGFGYS--DCGGHPQWYEPTEWL
MMAR_3639|M.marinum_M RSPIR----YLNDGVSQLQFVRADGTVPRLAFP--TATGRAVFFARPHLV
MUL_1474|M.ulcerans_Agy99 RSPIR----YLNDGVSQLQFVRADGTVPRLAFP--TATGRAVFFARPHLV
MAV_4535|M.avium_104 LYEDGRFPAAPDYCEAYGKDLITGAPLQPDEYRSLNPSGKAIIKAAQYLP
TH_4041|M.thermoresistible__bu PRRLRENPHGIVVADR-VPTGVLGKVVRHRGGR--VCLAPDEVVAEVHRL
. : .
Mb1477|M.bovis_AF2122/97 GGPR--AARYPLHLIANQPRTRLHSQLDHGGASMASKIRGREPIRIHPDD
Rv1442|M.tuberculosis_H37Rv GGPR--AARYPLHLIANQPRTRLHSQLDHGGASMASKIRGREPIRIHPDD
Mflv_3958|M.gilvum_PYR-GCK GGPR--AADYPLHLVANQPAGRLHGQLDAGAASQATKVAGREPIRMHPAD
Mvan_2438|M.vanbaalenii_PYR-1 GGPR--AERYPLHLLANQPASRLHSQLDGGATSQASKVAGREPVRMHPDD
MSMEG_2738|M.smegmatis_MC2_155 GGER--ARRYPLHLLANQPASRLHSQLDGGATSQSSKVQGREPVRMHPSD
MAB_3041|M.abscessus_ATCC_1997 GGER--AQRFPLHLIANQPRTRLHSQLDFGGTSQGSKVRGREPLRIHPQD
MMAR_3639|M.marinum_M PDEMP-DGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDD
MUL_1474|M.ulcerans_Agy99 PDEMP-DGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDD
MAV_4535|M.avium_104 PHERP-GPDYPFALITGRTIYHFHTRTKTARAQQLQDAAPEVWVEVSERD
TH_4041|M.thermoresistible__bu GQRHPDDPAYPLLAIGMREMRSQNTWMHN--SPTLMKGDRRHRARIHPAD
:*: : : . . .: *
Mb1477|M.bovis_AF2122/97 AAARELTDGDIVRVFNDRGACLAGVVIDDGLRP----------------K
Rv1442|M.tuberculosis_H37Rv AAARELTDGDIVRVFNDRGACLAGVVIDDGLRP----------------K
Mflv_3958|M.gilvum_PYR-GCK AHARDLSGGDVVRVFNDRGACLAGVVLDDRVRP----------------Q
Mvan_2438|M.vanbaalenii_PYR-1 AAERGLAAGDVVRMFNDSGACLAGVVLDDRVRP----------------R
MSMEG_2738|M.smegmatis_MC2_155 AAARGLADGDVVRVFNDRGACLAGVVIDDGVLP----------------R
MAB_3041|M.abscessus_ATCC_1997 AATRGIADGDVVRVFNDRGACLAGAVLDEGLRR----------------Q
MMAR_3639|M.marinum_M AADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYL
MUL_1474|M.ulcerans_Agy99 AADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYL
MAV_4535|M.avium_104 ARRLGIEAGDLVHVSTPRGRITCAARVGG---------------------
TH_4041|M.thermoresistible__bu AAAAGVTHGGPVRIESPYGAIETEALCTDEMTP-----------------
* : *. :.: . * .
Mb1477|M.bovis_AF2122/97 VVQLSTGAWFDPAD-----------------------PRDPDSMCVHGNP
Rv1442|M.tuberculosis_H37Rv VVQLSTGAWFDPAD-----------------------PRDPDSMCVHGNP
Mflv_3958|M.gilvum_PYR-GCK VVQLSTGAWFDPAD-----------------------PADPHSMCVHGNP
Mvan_2438|M.vanbaalenii_PYR-1 VVQLSTGAWFDPAD-----------------------PADPDSMCVHGNP
MSMEG_2738|M.smegmatis_MC2_155 VVQLATGAWYDPAD-----------------------PADPDSLCLHGNP
MAB_3041|M.abscessus_ATCC_1997 VVQLSTGAWFDPIE-----------------------PADPNSACAHGNP
MMAR_3639|M.marinum_M SINAVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADTCADATA
MUL_1474|M.ulcerans_Agy99 SINAVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADACADATA
MAV_4535|M.avium_104 ---IRDGVLFVPFHYG---------------------YWDRDGGDHQRAG
TH_4041|M.thermoresistible__bu ------GTVAIPHG--------------------------WGHNGGWRLA
. *
Mb1477|M.bovis_AF2122/97 NALSNDSGTSSLAHGSTGQHVLVQIERFTGELPP----------------
Rv1442|M.tuberculosis_H37Rv NALSNDSGTSSLAHGSTGQHVLVQIERFTGELPP----------------
Mflv_3958|M.gilvum_PYR-GCK NVLTDDVGTSKLAHGCTGAHVLVQIEKYAGTPPP----------------
Mvan_2438|M.vanbaalenii_PYR-1 NMLTDDVGTSALAHGCTGAHALVQIEKYTAAPPP----------------
MSMEG_2738|M.smegmatis_MC2_155 NVLTDDVGTSSLAKGCTGAHVLVEIEKFAGPVPP----------------
MAB_3041|M.abscessus_ATCC_1997 NVLTDDSGTSSLAQGCTGQHVLVQIERFEGTPPP----------------
MMAR_3639|M.marinum_M PKLLADTAQFSVTQVDALAELLGVANEPTPQFGPFARSYLAGLIAGLRSE
MUL_1474|M.ulcerans_Agy99 PKLLADTAQFSVTQVDALAELLGVGNEPTPQFGPSARSYLAGLIAGLRSE
MAV_4535|M.avium_104 NELTATDWDPASKQPSFKTAAARLDMAPTHTAAP----------------
TH_4041|M.thermoresistible__bu NRLAGANVNELTSNDSADLERLAGMSVLNGVPVR----------------
* :
Mb1477|M.bovis_AF2122/97 ---------------------------------VRAHEPPRLA-------
Rv1442|M.tuberculosis_H37Rv ---------------------------------VRAHEPPRLA-------
Mflv_3958|M.gilvum_PYR-GCK ---------------------------------VRAHQPPVFTPR-----
Mvan_2438|M.vanbaalenii_PYR-1 ---------------------------------VRAHQPPVFAAR-----
MSMEG_2738|M.smegmatis_MC2_155 ---------------------------------VRAHEPPVIRTLR----
MAB_3041|M.abscessus_ATCC_1997 ---------------------------------VRAHTPPRFVARD----
MMAR_3639|M.marinum_M TGRRMAGVPTLPVSSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGA
MUL_1474|M.ulcerans_Agy99 TGRRMAGVSTLPISSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGA
MAV_4535|M.avium_104 ---------------------------------VSEAVAAGSPS------
TH_4041|M.thermoresistible__bu ------------------------------------LVPVG---------
.
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M AAQSDNAAEAAVEQPPIVVLWASQTGTAEELAASVAAQLSAAELPVVLHG
MUL_1474|M.ulcerans_Agy99 AAQSDNAAEAAVEQPPIVVLWASQTGTAEELAASVAAQLSAAELPVVLHG
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M MDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAATAPSLAGTR
MUL_1474|M.ulcerans_Agy99 MDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAPTAPSLAGTR
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M YSVLALGDSNYADFCGHGRALDHRLAELGASRVTDRVDCEPDYEESAARW
MUL_1474|M.ulcerans_Agy99 YSVLALGDSNYADFCGHGRALDHRLAELGASRITDRVDCEPDYEESAARW
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M LQEVLDGLRRTAPPVITAAPVRAASIANRPQGYTKKRPLLTSVMRNTTLS
MUL_1474|M.ulcerans_Agy99 LQEVLDGLRRTAPPVITAEPVRAASIASRPQGYTKKRPLLTSVMRNTTLS
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M RPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQLVDEWLGVTQLDG
MUL_1474|M.ulcerans_Agy99 RPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQLVDEWLGVTRLDG
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M HTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQRTLDSNTANQLAE
MUL_1474|M.ulcerans_Agy99 HTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQRTLDSNTANQLAE
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M LMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSVLKPIQPRLYSIS
MUL_1474|M.ulcerans_Agy99 LMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSVLKPIQPRLYSIS
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M SSPKEHPGEVHLTVSPVRYNFQGVPRRGVCSTYLADRSPSDQIAIYVRKS
MUL_1474|M.ulcerans_Agy99 SSPKEHPGEVHLTVSPVRYNFQGVPRRGVCSTYLADRSPSDQIAIYVRKS
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M SNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGHTGPNWLFFGEQHA
MUL_1474|M.ulcerans_Agy99 SNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGHTGPNWLFFGEQHA
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M ATDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVYVQHLMQQRGAQLWQW
MUL_1474|M.ulcerans_Agy99 ATDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVYVQHLMQQRGAQLWQW
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M LQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLDPESATAFVHALSADK
MUL_1474|M.ulcerans_Agy99 LQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLDPESATAFVHALSADK
MAV_4535|M.avium_104 --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
Mb1477|M.bovis_AF2122/97 -------
Rv1442|M.tuberculosis_H37Rv -------
Mflv_3958|M.gilvum_PYR-GCK -------
Mvan_2438|M.vanbaalenii_PYR-1 -------
MSMEG_2738|M.smegmatis_MC2_155 -------
MAB_3041|M.abscessus_ATCC_1997 -------
MMAR_3639|M.marinum_M RYHRDVY
MUL_1474|M.ulcerans_Agy99 RYHRDVY
MAV_4535|M.avium_104 -------
TH_4041|M.thermoresistible__bu -------