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PHSPTSLTHWGVFSAEIVDGDIAAVNPPPDDADPSPLLGNMPGSIRHRARITGPAVRRGWLRDGPGPSTE RGADEFVAVSWDELTDLLATELRRVVDTYGNEAIYGGSYGWSSAGRFHHAQSQVHRFLKMLGGYTFSRHS YSLGATGAIMPRVVGTHDDLFKRSTQWDVIVEHTGLMVCFGGMPLKNTGINDGGTSAHPMRDALRRFRGR GGRIVSFSPLRDDVDGDCQWLALRPGTDVAVMLGLAYVLATEGLADREFLDTHCTGYERFERYLLGHDDG VAKSPEWAAHISGLSADTLRALAHRMAAERTIVTVSWSLQRTRHGEQAPWMGVTLAAMLGQIGLPGGGFG HGYGSMNEPGLAPLRCRLPSLPQGPNPVRTFIPVAAVTDMLLHPGEPFDYNGLRLTYPDIKCVYWSGGNP FHHHQNIPRLRRALGRVDTIVVHDPYWTAMAKHADIVVPSTTSFERNDFSGSKNDPLLVAMPQLAEPYAD SRDDYTTFSALAERLGFGEQFTEGRTAWEWLVHLYEKWAAGLDFAVPSFAEFWAAGHVELPTDTGLTLFE DFRADPQAHPLGTPSGRIEIFSEDIDSFGYDDCAGHPRWYEPAEWLGGERARRYPLHLLANQPASRLHSQ LDGGATSQSSKVQGREPVRMHPSDAAARGLADGDVVRVFNDRGACLAGVVIDDGVLPRVVQLATGAWYDP ADPADPDSLCLHGNPNVLTDDVGTSSLAKGCTGAHVLVEIEKFAGPVPPVRAHEPPVIRTLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2738 | - | - | 100% (763) | biotin sulfoxide reductase |
| M. smegmatis MC2 155 | MSMEG_6816 | - | 2e-42 | 26.50% (702) | molybdopterin oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_0161 | - | 8e-24 | 23.80% (647) | formate dehydrogenase, alpha subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1477 | bisC | 0.0 | 70.13% (760) | biotin sulfoxide reductase |
| M. gilvum PYR-GCK | Mflv_3958 | - | 0.0 | 77.69% (753) | molybdopterin guanine dinucleotide-containing S/N-oxide |
| M. tuberculosis H37Rv | Rv1442 | bisC | 0.0 | 70.13% (760) | biotin sulfoxide reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3041 | - | 0.0 | 76.56% (751) | putative biotin sulfoxide reductase BisC |
| M. marinum M | MMAR_2605 | - | 6e-16 | 22.65% (671) | anaerobic dehydrogenase |
| M. avium 104 | MAV_4535 | - | 2e-16 | 23.31% (502) | nitrate reductase NarB |
| M. thermoresistible (build 8) | TH_4041 | - | 2e-28 | 26.65% (514) | PUTATIVE Formate dehydrogenase |
| M. ulcerans Agy99 | MUL_1474 | fdhF | 9e-13 | 21.43% (504) | formate dehydrogenase H FdhF |
| M. vanbaalenii PYR-1 | Mvan_2438 | - | 0.0 | 79.15% (753) | molybdopterin guanine dinucleotide-containing S/N-oxide |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1477|M.bovis_AF2122/97 -------------------------------------MQVYTSATHWGVF
Rv1442|M.tuberculosis_H37Rv -------------------------------------MQVYTSATHWGVF
Mflv_3958|M.gilvum_PYR-GCK MLQSTSITKSPRRIDSKERRLFHPSFRRNGVRRLSCVARTRTSLTHWGAF
Mvan_2438|M.vanbaalenii_PYR-1 MVG-----------------------RGGRAVRLSSVSATQTSLTHWGAF
MSMEG_2738|M.smegmatis_MC2_155 ------------------------------------MPHSPTSLTHWGVF
MAB_3041|M.abscessus_ATCC_1997 -------------------------MIRPAFSAVQVSGSARLSHTHWGAF
MMAR_2605|M.marinum_M -------------------------------------MATVDDGRHLHTC
TH_4041|M.thermoresistible__bu ----------------------------------------MATEQRVTYC
MUL_1474|M.ulcerans_Agy99 --------------------------------------MAPNKDAVKTVC
MAV_4535|M.avium_104 -------MATDRIANPWGTRTPYAPGTRWPERIDTYLADGVTAESVDRWV
Mb1477|M.bovis_AF2122/97 TARVHGGDIAAVAALASDTNPAPQLQNLPG--AVRHRSRIANPAVRRGWL
Rv1442|M.tuberculosis_H37Rv TARVHGGDIAAVAALASDTNPAPQLQNLPG--AVRHRSRIANPAVRRGWL
Mflv_3958|M.gilvum_PYR-GCK SATVESGDIASVRPWSGDADPSPALGNLPG--SVRHRSRVTAPAVRRGWL
Mvan_2438|M.vanbaalenii_PYR-1 SATVEAGEITAVAPVAGDDDPSVALGNLPG--SVRHISRVTTPAVRRGWL
MSMEG_2738|M.smegmatis_MC2_155 SAEIVDGDIAAVNPPPDDADPSPLLGNMPG--SIRHRARITGPAVRRGWL
MAB_3041|M.abscessus_ATCC_1997 TPEVRDGEVIGVTPIETDLDPSPLLQNIPG--SIRHQARVTAPAVRSGWL
MMAR_2605|M.marinum_M PLCEAMCGLEIRVADGPSGGRVVGIRGNRD--DVWSRGHICPKGASLGAL
TH_4041|M.thermoresistible__bu RICEPLCGLIATVEDG----RLQSLRPDPD--HPLSRGRACPKGIAFTEV
MUL_1474|M.ulcerans_Agy99 AYCGVGCGIVLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADL
MAV_4535|M.avium_104 QSAAVLHSNGDGLDIAVKDGRIVGVRGRAV--DRVNHGRLDPKDLFGWQA
.:
Mb1477|M.bovis_AF2122/97 QHGPG-----PSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYG
Rv1442|M.tuberculosis_H37Rv QHGPG-----PSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYG
Mflv_3958|M.gilvum_PYR-GCK ENGPG-----PDTLLGADEFVAVTWDDLVELLGGELRRVIDTHGNEAIYG
Mvan_2438|M.vanbaalenii_PYR-1 DHGPG-----PDDSRGADDFVAVTWDELTELLGDELRRVIDTHGNGAIYG
MSMEG_2738|M.smegmatis_MC2_155 RDGPG-----PSTERGADEFVAVSWDELTDLLATELRRVVDTYGNEAIYG
MAB_3041|M.abscessus_ATCC_1997 REGPG-----PSDKRGADEYVEVSWDELTELLADELRRVVDTHGNEAIYG
MMAR_2605|M.marinum_M HDDPDRIR-HPMIK-IDGQWHEVSWDAAFRRCTELLAPVIDTYGIGAVT-
TH_4041|M.thermoresistible__bu QNDPDRVL-YPLRRRADGEFERVGWDEALDDIAARLTAIRDRHGGGAIG-
MUL_1474|M.ulcerans_Agy99 LAAPGRMESAHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHGPDAVG-
MAV_4535|M.avium_104 NASADRLT--TPLLRVRGALRPCDWDTAMERIVARSRELLDRHGPSSIG-
.. * * :* ::
Mb1477|M.bovis_AF2122/97 SSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGA
Rv1442|M.tuberculosis_H37Rv SSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGA
Mflv_3958|M.gilvum_PYR-GCK GSYGWSSAGRFHHAQSQVHRFLNCLGGYTYSRHSYSLGATGVIMPRVVG-
Mvan_2438|M.vanbaalenii_PYR-1 GSYGWSSAGRFHHAQSQVHRFLNCLGGYTFSRHSYSLGATGVIMPRVVG-
MSMEG_2738|M.smegmatis_MC2_155 GSYGWSSAGRFHHAQSQVHRFLKMLGGYTFSRHSYSLGATGAIMPRVVG-
MAB_3041|M.abscessus_ATCC_1997 GSYGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGVIMPHVIG-
MMAR_2605|M.marinum_M -----AYTGNPLAHSFSLARYAGVLLGMSGMPVTYSPGTVDQWPKNLSSH
TH_4041|M.thermoresistible__bu -----QYFGNPVAFGYATALWSGMFVARLGSRHQYSSGSQDINSRFVASK
MUL_1474|M.ulcerans_Agy99 ---VYVSGQMSIEAQYLANKLTKGFIGTKQIESNSRLCMAGASSGYKLSL
MAV_4535|M.avium_104 ---FYTSGQLFAEEYYTQAAIAHGAIGTNHVDGNTRLCTATAAEALKESF
. .
Mb1477|M.bovis_AF2122/97 ALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHP-DRDYV
Rv1442|M.tuberculosis_H37Rv ALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHP-DRDYV
Mflv_3958|M.gilvum_PYR-GCK THDDLFTRSTQWQVIVENTDTMVCFGGLALKNTAVNDGGTTAHP-ARDAL
Mvan_2438|M.vanbaalenii_PYR-1 THDDLFKRSTQWDVIVEHTDLMVCFGGVALKNTGVNHGGTTAHP-ARGAL
MSMEG_2738|M.smegmatis_MC2_155 THDDLFKRSTQWDVIVEHTGLMVCFGGMPLKNTGINDGGTSAHP-MRDAL
MAB_3041|M.abscessus_ATCC_1997 THDGLFKRSTSWDVIVENTDLLIAFGGIALKNTGVNHGGTTAHP-ARDAL
MMAR_2605|M.marinum_M LMYGGWWTFPVPD--IERTDLLVIMG----ANPAASQGSLLAAPDVMGLI
TH_4041|M.thermoresistible__bu LLYGAASQIPFPD--LPRTDFLFMLG----ANPFVSHGSALRAPRIKDDL
MUL_1474|M.ulcerans_Agy99 GADGPPGSYQDFD----HADVFLVIG----------ANMADCHPILFLRM
MAV_4535|M.avium_104 GCDGQPGSYTDVD----HADVIALFG----------HNVAETQTVLWARM
: .: : :* . . :
Mb1477|M.bovis_AF2122/97 GRYRARGG--RLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGL
Rv1442|M.tuberculosis_H37Rv GRYRARGG--RLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGL
Mflv_3958|M.gilvum_PYR-GCK NRLRARGG--RIVSFSPLRDDV-------DGPCDWHAPVPGTDVAIMLAL
Mvan_2438|M.vanbaalenii_PYR-1 DRFRARGG--HLVSFSPLRDDV-------DGPCDWFAPVPGTDVAIMLAL
MSMEG_2738|M.smegmatis_MC2_155 RRFRGRGG--RIVSFSPLRDDV-------DGDCQWLALRPGTDVAVMLGL
MAB_3041|M.abscessus_ATCC_1997 NRFRDRGG--RIVSFSPLHDDI-------DGECEWHAPIPGTDVAVMLAL
MMAR_2605|M.marinum_M DAIRQRGK--VIVIDPVRTVTA-------ARADEWLPIVPGTDAALLLAV
TH_4041|M.thermoresistible__bu TDITRRGG--RVVVVDPRRTET-------ARAFEHIAVRPDSDAWLLLSM
MUL_1474|M.ulcerans_Agy99 MERVKSGA--KLIVVDPRRTAT------ADKADLFLQIAPGTDLALLNGL
MAV_4535|M.avium_104 LDRLAGSDPPAIVCVDPRLTPVAR------HATVHLAPLPGTNVALMNGL
. :: *.:: :: .:
Mb1477|M.bovis_AF2122/97 AYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLA
Rv1442|M.tuberculosis_H37Rv AYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLA
Mflv_3958|M.gilvum_PYR-GCK AHVLATESLADREFLASHCTGYDRFERYLLGADDGIPKSPQWASSLCGLS
Mvan_2438|M.vanbaalenii_PYR-1 AHVLAAESLADRDFLATYCTGYDRFERYLLGVDDGTPKSPQWAAQICGLD
MSMEG_2738|M.smegmatis_MC2_155 AYVLATEGLADREFLDTHCTGYERFERYLLGHDDGVAKSPEWAAHISGLS
MAB_3041|M.abscessus_ATCC_1997 AHVLAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPKSPEWAAPISGLD
MMAR_2605|M.marinum_M AHTLFDEDLVN---PGPHVDGVDTMRRVAADWP------PARVSAVTGIE
TH_4041|M.thermoresistible__bu LQVIFAEGLEDTAAIARQTTGCSTLRGLVAGFP------PEATAARTGVP
MUL_1474|M.ulcerans_Agy99 LHLIVENEQTDPQFISEFTEGWEVMPSFLEQFT------PDRVSEITGIP
MAV_4535|M.avium_104 LHEIIGNGWIDRDYIDAHSVGFDELQCRVSEFT------PEWVAEICGVA
: : : * . : * .: *:
Mb1477|M.bovis_AF2122/97 AGDLRDLARRMAEHRTLITTSLS-LQRIEHGEQTVWMAATLAAMLGQIGL
Rv1442|M.tuberculosis_H37Rv AGDLRDLARRMAEHRTLITTSLS-LQRIEHGEQTVWMAATLAAMLGQIGL
Mflv_3958|M.gilvum_PYR-GCK ADDLTALARRMAAGRTLVTVSWS-LQRTRHGEQAPWMGLTLAAMLGQIGL
Mvan_2438|M.vanbaalenii_PYR-1 ADDLTALARRMAACRTIVTVSWS-LQRTRHGEQAPWMGLTLAAMLGQIGL
MSMEG_2738|M.smegmatis_MC2_155 ADTLRALAHRMAAERTIVTVSWS-LQRTRHGEQAPWMGVTLAAMLGQIGL
MAB_3041|M.abscessus_ATCC_1997 AAELRTLARRMAAGRTLVTVSWS-LQRVRHGEQAPWMGLTLAAMLGQIGL
MMAR_2605|M.marinum_M EERIRRLARELAGTHKSVVYGRIGLCNQEFGSLASWLVDVINILTGHFDT
TH_4041|M.thermoresistible__bu ADVVRSLARDFAAAPTAAAYGRTGACLGRHGTLVSFLLDALSIVTGNLDR
MUL_1474|M.ulcerans_Agy99 SEDIRTAARWIGTAANWMSCWTMGLNQSTHGTWNTNALCNLHLATGAICR
MAV_4535|M.avium_104 ATDLRRAARLIGTAQRLLSTVLQGFYQSHQATAAAVQVNNIHLVRGMLGR
: *: :. . : * :
Mb1477|M.bovis_AF2122/97 PGGGFGHGY---SSNGVGNPPLACGLPALPQ------GNNPVSTFIPVAA
Rv1442|M.tuberculosis_H37Rv PGGGFGHGY---SSNGVGNPPLACGLPALPQ------GNNPVSTFIPVAA
Mflv_3958|M.gilvum_PYR-GCK PGGGFGHGYG--SMNEAGLAPIRCGLPRLPQ------GVNPVTTFIPVAA
Mvan_2438|M.vanbaalenii_PYR-1 PGGGFGHGYG--SMNEPGLAPVRCGLPRLPQ------GINPVTTFIPVAA
MSMEG_2738|M.smegmatis_MC2_155 PGGGFGHGYG--SMNEPGLAPLRCRLPSLPQ------GPNPVRTFIPVAA
MAB_3041|M.abscessus_ATCC_1997 PGGGFGHGYG--SMNEPGLAPVSCPLPTFPQ------GPNPVETFIPVAA
MMAR_2605|M.marinum_M PGGAMFPRPAAWSITTQPLPGLEGGVAEFGRWHTRVRGAKEVLGQAPVSC
TH_4041|M.thermoresistible__bu EGGLLMAH----AVIPFEELGERTGRLTYGTERSRIGGLPEVISTFPAAL
MUL_1474|M.ulcerans_Agy99 PGSGPFSLTG----QPNAMGGREMGYMGPGLP-----GQRSVLSAPDREF
MAV_4535|M.avium_104 PGCGVLQMNGQPTAENTRECGADGDLAGFRN-----WSNDSHVAELADLW
* .
Mb1477|M.bovis_AF2122/97 ISELLQRPGQRLAYNGR--------LLELPDIKCVYWAGGNPFHHHQNLP
Rv1442|M.tuberculosis_H37Rv ISELLQRPGQRLAYNGR--------LLELPDIKCVYWAGGNPFHHHQNLP
Mflv_3958|M.gilvum_PYR-GCK VSDMLLHPGEPFDYNGL--------RLTYPDIRLVYWAGGNPFHHHQNLP
Mvan_2438|M.vanbaalenii_PYR-1 VSDMLLSPGEPFDYNGL--------RLHYPDIRLVYWAGGNPFHHHQNIP
MSMEG_2738|M.smegmatis_MC2_155 VTDMLLHPGEPFDYNGL--------RLTYPDIKCVYWSGGNPFHHHQNIP
MAB_3041|M.abscessus_ATCC_1997 ISELLLRPGQTLAYNGQ--------TLTLPDIRCVYWAGGNPFHHHQNLP
MMAR_2605|M.marinum_M LAEEIATPGD-------------------GQLRALITIAGNPVLSTPGGD
TH_4041|M.thermoresistible__bu MADEINTPGD-------------------GQLRALFVTAGNPVLTVPNGP
MUL_1474|M.ulcerans_Agy99 VEEQWGLPGGALRTDVSGGVIDMFSRMADGEIKACWIICSNPVATVANRK
MAV_4535|M.avium_104 NLEPLQIPHYGPPTHAMQMFR----FAEEGTLRMLWVTATNPAVSLPELP
: * :: **
Mb1477|M.bovis_AF2122/97 RLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDFAASKTNPTL
Rv1442|M.tuberculosis_H37Rv RLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDFAASKTNPTL
Mflv_3958|M.gilvum_PYR-GCK RLRRALSRPDTVVVHDPYWTAMAKHADIVVPSTTFAERDDLSGSRNDPML
Mvan_2438|M.vanbaalenii_PYR-1 RLRRALRRPDTVVVHDPYWTPMAKHADIVVPSTTFAERHDFSGSRNDPVL
MSMEG_2738|M.smegmatis_MC2_155 RLRRALGRVDTIVVHDPYWTAMAKHADIVVPSTTSFERNDFSGSKNDPLL
MAB_3041|M.abscessus_ATCC_1997 RLRRALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDDFSGSRNDPLL
MMAR_2605|M.marinum_M KLDEALSSLEAMISVDLWLNETTRHADVILPGLSPLEQPHHDDLVLQFAI
TH_4041|M.thermoresistible__bu ALEKVLGKLDLIVSLDFYVTETNRHAHYVLPATTFLERDDYPYGFAANCP
MUL_1474|M.ulcerans_Agy99 TVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDGVMVNCERNM
MAV_4535|M.avium_104 RIRDILSQQRLFLVVQDIFLTETAALADVVLPAAAWAEKTGTFTNADRTV
: * .: : :: : .
Mb1477|M.bovis_AF2122/97 IAMPAMVPPYANA----RDDYHTFSALAHRLG-------FGKQFTEGRSA
Rv1442|M.tuberculosis_H37Rv IAMPAMVPPYANA----RDDYHTFSALAHRLG-------FGKQFTEGRSA
Mflv_3958|M.gilvum_PYR-GCK MAMPRLTETYAQA----RDDYDTYAALAGHLG-------VRQAFTEGRSS
Mvan_2438|M.vanbaalenii_PYR-1 MAMRRLAEPYAQA----RDDYDTFAALARRLG-------VADTFTEGRTS
MSMEG_2738|M.smegmatis_MC2_155 VAMPQLAEPYADS----RDDYTTFSALAERLG-------FGEQFTEGRTA
MAB_3041|M.abscessus_ATCC_1997 VAMKAVAPPYANS----RDDYTTFSALADRLG-------FGEQFSEGRTA
MMAR_2605|M.marinum_M RSFANYSAPVFDP-GDRPHEWEILIRLTGLCTGTPAEDVDVAAIDDGFFD
TH_4041|M.thermoresistible__bu TVFIQSAEPVVGAYGEARNEWEVFDELARRMG--------LSLFATGPLE
MUL_1474|M.ulcerans_Agy99 SLFPKAVDPVGDA----LPDWQIIARIACEMG------FSESFSYSSAAE
MAV_4535|M.avium_104 HLSEKAVEPPGSA----RSDLEIFLDYARRMDFR----DKDGRPFPPWTD
. . : :
Mb1477|M.bovis_AF2122/97 REWLEHMYDKWSAELDFP--------VPSFAEFWRTG--RLELPT----R
Rv1442|M.tuberculosis_H37Rv REWLEHMYDKWSAELDFP--------VPSFAEFWRTG--RLELPT----R
Mflv_3958|M.gilvum_PYR-GCK RQWLRHIYETWSRTLDFD--------VPAFDGFWAAG--ALRLPT----D
Mvan_2438|M.vanbaalenii_PYR-1 AQWLRHLYEKWSATLDFE--------VPSFDEFWQVG--QVRLPT----D
MSMEG_2738|M.smegmatis_MC2_155 WEWLVHLYEKWAAGLDFA--------VPSFAEFWAAG--HVELPT----D
MAB_3041|M.abscessus_ATCC_1997 AQWLRHIYTEWAGALNFS--------VPSFDEFWDRG--YLELPT----D
MMAR_2605|M.marinum_M YLAFTKGFDGAAIRKRYEHDGWAGGPERILDLTLRTGPFGDRYGQ----N
TH_4041|M.thermoresistible__bu RLNPVLAWLDRRGVGRLT-------PRRLMELLLRLGPYGDRFGL----R
MUL_1474|M.ulcerans_Agy99 VFEEIKRFSNPATGYDLR--------GISHDRLRETP---LQWPC----P
MAV_4535|M.avium_104 PESAFEAWKKCSAGRPCDYT------GLSYAKLRGGS--GIQWPCNTDHP
: .
Mb1477|M.bovis_AF2122/97 TGLTWLADFRADPAAHPLGTPSGRIEIFSDTVDAFALP--DCAGHPTWYE
Rv1442|M.tuberculosis_H37Rv TGLTWLADFRADPAAHPLGTPSGRIEIFSDTVDAFALP--DCAGHPTWYE
Mflv_3958|M.gilvum_PYR-GCK DGLTLLADFRADPSAHPLATPSGRIEIFSADIDSFGYD--DCRGHPAWFE
Mvan_2438|M.vanbaalenii_PYR-1 EGLTLFADFRADPSAHRLATPSGRIEIFSADIAGFGYR--DCVGHPAWFE
MSMEG_2738|M.smegmatis_MC2_155 TGLTLFEDFRADPQAHPLGTPSGRIEIFSEDIDSFGYD--DCAGHPRWYE
MAB_3041|M.abscessus_ATCC_1997 AGLTLLSDFRENPAAHPLHTPSGRIEIFSETIDGFGYS--DCGGHPQWYE
MMAR_2605|M.marinum_M PGGLTLDMLKANPNGIDFG-PMVSQ--LPDILGTPEKK--IRLAPQYLLD
TH_4041|M.thermoresistible__bu RGGLNPRRLRENPHGIVVA-DRVPTGVLGKVVRHRGGR--VCLAPDEVVA
MUL_1474|M.ulcerans_Agy99 PDGASN---RSPIRYLNDGVSQLQFVRADGTVPRLAFP--TATGRAVFFA
MAV_4535|M.avium_104 DGIERLYEDGRFPAAPDYCEAYGKDLITGAPLQPDEYRSLNPSGKAIIKA
. : .
Mb1477|M.bovis_AF2122/97 PSEWLGGPRAARYPLHLIAN-QPRTRLHSQLDHGGASMASKIRGREPIRI
Rv1442|M.tuberculosis_H37Rv PSEWLGGPRAARYPLHLIAN-QPRTRLHSQLDHGGASMASKIRGREPIRI
Mflv_3958|M.gilvum_PYR-GCK PTEWLGGPRAADYPLHLVAN-QPAGRLHGQLDAGAASQATKVAGREPIRM
Mvan_2438|M.vanbaalenii_PYR-1 PAEWLGGPRAERYPLHLLAN-QPASRLHSQLDGGATSQASKVAGREPVRM
MSMEG_2738|M.smegmatis_MC2_155 PAEWLGGERARRYPLHLLAN-QPASRLHSQLDGGATSQSSKVQGREPVRM
MAB_3041|M.abscessus_ATCC_1997 PTEWLGGERAQRFPLHLIAN-QPRTRLHSQLDFGGTSQGSKVRGREPLRI
MMAR_2605|M.marinum_M DLPRLASR-MDRPAEQLVLV-NRRHLRSNNSWLHNVPALMKGKDRCTLLM
TH_4041|M.thermoresistible__bu EVHRLGQRHPDDPAYPLLAI-GMREMRSQNTWMHNSPTLMKGDRRHRARI
MUL_1474|M.ulcerans_Agy99 RPHLVPDEMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEV
MAV_4535|M.avium_104 AQYLPPHERPGPDYPFALITGRTIYHFHTRTKTARAQQLQDAAPEVWVEV
: . :
Mb1477|M.bovis_AF2122/97 HPDDAAARELTDGDIVRVFNDRGACLAGVVIDDGLRPKVVQLSTGA----
Rv1442|M.tuberculosis_H37Rv HPDDAAARELTDGDIVRVFNDRGACLAGVVIDDGLRPKVVQLSTGA----
Mflv_3958|M.gilvum_PYR-GCK HPADAHARDLSGGDVVRVFNDRGACLAGVVLDDRVRPQVVQLSTGA----
Mvan_2438|M.vanbaalenii_PYR-1 HPDDAAERGLAAGDVVRMFNDSGACLAGVVLDDRVRPRVVQLSTGA----
MSMEG_2738|M.smegmatis_MC2_155 HPSDAAARGLADGDVVRVFNDRGACLAGVVIDDGVLPRVVQLATGA----
MAB_3041|M.abscessus_ATCC_1997 HPQDAATRGIADGDVVRVFNDRGACLAGAVLDEGLRRQVVQLSTGA----
MMAR_2605|M.marinum_M HPDDAARNGITDNDTVTVRSSAGEITVPVELTSAIKPGVVSMPHGW----
TH_4041|M.thermoresistible__bu HPADAAAAGVTHGGPVRIESPYGAIETEALCTDEMTPGTVAIPHGW----
MUL_1474|M.ulcerans_Agy99 HPDDAADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAF
MAV_4535|M.avium_104 SERDARRLGIEAGDLVHVSTPRGRITCAARVGG-IRDGVLFVPFHYG---
** : .. : : . * . : .
Mb1477|M.bovis_AF2122/97 -----------------WFDPADPRDPDSMCVHGNPNALSNDSGTSSLAH
Rv1442|M.tuberculosis_H37Rv -----------------WFDPADPRDPDSMCVHGNPNALSNDSGTSSLAH
Mflv_3958|M.gilvum_PYR-GCK -----------------WFDPADPADPHSMCVHGNPNVLTDDVGTSKLAH
Mvan_2438|M.vanbaalenii_PYR-1 -----------------WFDPADPADPDSMCVHGNPNMLTDDVGTSALAH
MSMEG_2738|M.smegmatis_MC2_155 -----------------WYDPADPADPDSLCLHGNPNVLTDDVGTSSLAK
MAB_3041|M.abscessus_ATCC_1997 -----------------WFDPIEPADPNSACAHGNPNVLTDDSGTSSLAQ
MMAR_2605|M.marinum_M -----------------GHGKP---GTRLAVANSAPGVNTNVLSPPTLLD
TH_4041|M.thermoresistible__bu -----------------GHNG----GWRLANRLAGANVNELTSNDSADLE
MUL_1474|M.ulcerans_Agy99 GEYLSINAVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADACA
MAV_4535|M.avium_104 -----------------YWDRDGGDHQRAGNELTATDWDPASKQPSFKTA
. .
Mb1477|M.bovis_AF2122/97 GSTGQHVLVQIERFTGELPPVRAHEPPRLA--------------------
Rv1442|M.tuberculosis_H37Rv GSTGQHVLVQIERFTGELPPVRAHEPPRLA--------------------
Mflv_3958|M.gilvum_PYR-GCK GCTGAHVLVQIEKYAGTPPPVRAHQPPVFTPR------------------
Mvan_2438|M.vanbaalenii_PYR-1 GCTGAHALVQIEKYTAAPPPVRAHQPPVFAAR------------------
MSMEG_2738|M.smegmatis_MC2_155 GCTGAHVLVEIEKFAGPVPPVRAHEPPVIRTLR-----------------
MAB_3041|M.abscessus_ATCC_1997 GCTGQHVLVQIERFEGTPPPVRAHTPPRFVARD-----------------
MMAR_2605|M.marinum_M EPSGNGVLNGIPVTVS----------------------------------
TH_4041|M.thermoresistible__bu RLAGMSVLNGVPVRLVPVG-------------------------------
MUL_1474|M.ulcerans_Agy99 DATAPKLLADTAQFSVTQVDALAELLGVGNEPTPQFGPSARSYLAGLIAG
MAV_4535|M.avium_104 AARLDMAPTHTAAPVSEAVAAGSPS-------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 LRSETGRRMAGVSTLPISSPFDTGTRLWLDGLLAGMFARAETPPALPFPQ
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 TPGAAAQSDNAAEAAVEQPPIVVLWASQTGTAEELAASVAAQLSAAELPV
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 VLHGMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAPTAPSL
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 AGTRYSVLALGDSNYADFCGHGRALDHRLAELGASRITDRVDCEPDYEES
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 AARWLQEVLDGLRRTAPPVITAEPVRAASIASRPQGYTKKRPLLTSVMRN
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 TTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQLVDEWLGVT
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 RLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQRTLDSNTAN
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 QLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSVLKPIQPRL
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 YSISSSPKEHPGEVHLTVSPVRYNFQGVPRRGVCSTYLADRSPSDQIAIY
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 VRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGHTGPNWLFFG
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 EQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVYVQHLMQQRGAQ
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2605|M.marinum_M --------------------------------------------------
TH_4041|M.thermoresistible__bu --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 LWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLDPESATAFVHAL
MAV_4535|M.avium_104 --------------------------------------------------
Mb1477|M.bovis_AF2122/97 -----------
Rv1442|M.tuberculosis_H37Rv -----------
Mflv_3958|M.gilvum_PYR-GCK -----------
Mvan_2438|M.vanbaalenii_PYR-1 -----------
MSMEG_2738|M.smegmatis_MC2_155 -----------
MAB_3041|M.abscessus_ATCC_1997 -----------
MMAR_2605|M.marinum_M -----------
TH_4041|M.thermoresistible__bu -----------
MUL_1474|M.ulcerans_Agy99 SADKRYHRDVY
MAV_4535|M.avium_104 -----------