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M. abscessus ATCC 19977 MAB_3041 (-)

annotation: putative biotin sulfoxide reductase BisC
coordinates: 3092259 - 3094583
length: 774

VIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDPSPLLQNIPGSIRHQARVTAPAVRS
GWLREGPGPSDKRGADEYVEVSWDELTELLADELRRVVDTHGNEAIYGGSYGWASAGRFHHAQSQVHRFL
KLLGGYTFSRHSYSLGATGVIMPHVIGTHDGLFKRSTSWDVIVENTDLLIAFGGIALKNTGVNHGGTTAH
PARDALNRFRDRGGRIVSFSPLHDDIDGECEWHAPIPGTDVAVMLALAHVLAVEKLADLTFLSSYCTGYE
RFERYLLGVDDGVPKSPEWAAPISGLDAAELRTLARRMAAGRTLVTVSWSLQRVRHGEQAPWMGLTLAAM
LGQIGLPGGGFGHGYGSMNEPGLAPVSCPLPTFPQGPNPVETFIPVAAISELLLRPGQTLAYNGQTLTLP
DIRCVYWAGGNPFHHHQNLPRLRRALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDDFSGSRNDPLL
VAMKAVAPPYANSRDDYTTFSALADRLGFGEQFSEGRTAAQWLRHIYTEWAGALNFSVPSFDEFWDRGYL
ELPTDAGLTLLSDFRENPAAHPLHTPSGRIEIFSETIDGFGYSDCGGHPQWYEPTEWLGGERAQRFPLHL
IANQPRTRLHSQLDFGGTSQGSKVRGREPLRIHPQDAATRGIADGDVVRVFNDRGACLAGAVLDEGLRRQ
VVQLSTGAWFDPIEPADPNSACAHGNPNVLTDDSGTSSLAQGCTGQHVLVQIERFEGTPPPVRAHTPPRF
VARD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3041--100% (774)putative biotin sulfoxide reductase BisC
M. abscessus ATCC 19977MAB_3870c-1e-2223.66% (655) molybdopterin oxidoreductase
M. abscessus ATCC 19977MAB_2438-9e-1722.22% (666) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1477bisC0.070.21% (762) biotin sulfoxide reductase
M. gilvum PYR-GCKMflv_3958-0.073.61% (758) molybdopterin guanine dinucleotide-containing S/N-oxide
M. tuberculosis H37RvRv1442bisC0.070.21% (762) biotin sulfoxide reductase
M. leprae Br4923-----
M. marinum MMMAR_2605-4e-1523.93% (422) anaerobic dehydrogenase
M. avium 104MAV_4535-4e-1422.73% (739) nitrate reductase NarB
M. smegmatis MC2 155MSMEG_2738-0.076.56% (751) biotin sulfoxide reductase
M. thermoresistible (build 8)TH_4483-8e-2525.62% (726) PUTATIVE Formate dehydrogenase
M. ulcerans Agy99MUL_1474fdhF2e-0920.68% (469) formate dehydrogenase H FdhF
M. vanbaalenii PYR-1Mvan_2438-0.073.83% (768) molybdopterin guanine dinucleotide-containing S/N-oxide

CLUSTAL 2.0.9 multiple sequence alignment


Mb1477|M.bovis_AF2122/97            -------------------------------------MQVYTSATHWGVF
Rv1442|M.tuberculosis_H37Rv         -------------------------------------MQVYTSATHWGVF
Mflv_3958|M.gilvum_PYR-GCK          MLQSTSITKSPRRIDSKERRLFHPSFRRNGVRRLSCVARTRTSLTHWGAF
Mvan_2438|M.vanbaalenii_PYR-1       MVG-----------------------RGGRAVRLSSVSATQTSLTHWGAF
MSMEG_2738|M.smegmatis_MC2_155      ------------------------------------MPHSPTSLTHWGVF
MAB_3041|M.abscessus_ATCC_1997      -------------------------MIRPAFSAVQVSGSARLSHTHWGAF
TH_4483|M.thermoresistible__bu      ----------------------------------------MTTVHTFCRY
MMAR_2605|M.marinum_M               -----------------------------------MATVDDGRHLHTCPL
MUL_1474|M.ulcerans_Agy99           ------------------------------------MAPNKDAVKTVCAY
MAV_4535|M.avium_104                -MATDRIANPWGTRTPYAPGTRWPERIDTYLADGVTAESVDRWVQSAAVL
                                                                                      

Mb1477|M.bovis_AF2122/97            TARVHGGDIAAVAA------LASDTNPAPQLQNLPGAVRHRSRIANPAVR
Rv1442|M.tuberculosis_H37Rv         TARVHGGDIAAVAA------LASDTNPAPQLQNLPGAVRHRSRIANPAVR
Mflv_3958|M.gilvum_PYR-GCK          SATVESGDIASVRP------WSGDADPSPALGNLPGSVRHRSRVTAPAVR
Mvan_2438|M.vanbaalenii_PYR-1       SATVEAGEITAVAP------VAGDDDPSVALGNLPGSVRHISRVTTPAVR
MSMEG_2738|M.smegmatis_MC2_155      SAEIVDGDIAAVNP------PPDDADPSPLLGNMPGSIRHRARITGPAVR
MAB_3041|M.abscessus_ATCC_1997      TPEVRDGEVIGVTP------IETDLDPSPLLQNIPGSIRHQARVTAPAVR
TH_4483|M.thermoresistible__bu      CLAACGVEVTVEDN------RVVNISADRANPHTWHDFCAKGRTAHQVVE
MMAR_2605|M.marinum_M               CEAMCGLEIRVADGPSGG--RVVGIRGNRDDVWSRGHICPKGASLGALHD
MUL_1474|M.ulcerans_Agy99           CGVGCGIVLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLLA
MAV_4535|M.avium_104                HSNGDGLDIAVKDG------RIVGVRGRAVDRVNHGRLDPKDLFGWQANA
                                            :                            .            

Mb1477|M.bovis_AF2122/97            RGWLQHGPGPSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYGS
Rv1442|M.tuberculosis_H37Rv         RGWLQHGPGPSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYGS
Mflv_3958|M.gilvum_PYR-GCK          RGWLENGPGPDTLLGADEFVAVTWDDLVELLGGELRRVIDTHGNEAIYGG
Mvan_2438|M.vanbaalenii_PYR-1       RGWLDHGPGPDDSRGADDFVAVTWDELTELLGDELRRVIDTHGNGAIYGG
MSMEG_2738|M.smegmatis_MC2_155      RGWLRDGPGPSTERGADEFVAVSWDELTDLLATELRRVVDTYGNEAIYGG
MAB_3041|M.abscessus_ATCC_1997      SGWLREGPGPSDKRGADEYVEVSWDELTELLADELRRVVDTHGNEAIYGG
TH_4483|M.thermoresistible__bu      HPRRILAP---MRRVGDRYVEADWDEAITDIATRLNALIDADGPDAIG--
MMAR_2605|M.marinum_M               DPDRIRHP---MIKIDGQWHEVSWDAAFRRCTELLAPVIDTYGIGAVT--
MUL_1474|M.ulcerans_Agy99           APGRMESAHLRAHRAG-HLESIPIDDAITQCAMRLRAIIDEHGPDAVGVY
MAV_4535|M.avium_104                SADRLTTP---LLRVRGALRPCDWDTAMERIVARSRELLDRHGPSSIGFY
                                           .                *             :*  *  ::   

Mb1477|M.bovis_AF2122/97            SYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGAA
Rv1442|M.tuberculosis_H37Rv         SYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGAA
Mflv_3958|M.gilvum_PYR-GCK          SYGWSSAGRFHHAQSQVHRFLNCLGGYTYSRHSYSLGATGVIMPRVVG-T
Mvan_2438|M.vanbaalenii_PYR-1       SYGWSSAGRFHHAQSQVHRFLNCLGGYTFSRHSYSLGATGVIMPRVVG-T
MSMEG_2738|M.smegmatis_MC2_155      SYGWSSAGRFHHAQSQVHRFLKMLGGYTFSRHSYSLGATGAIMPRVVG-T
MAB_3041|M.abscessus_ATCC_1997      SYGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGVIMPHVIG-T
TH_4483|M.thermoresistible__bu      LYYGNPTGYSTSNLIFMNAWLDAVG----TNNRYAVGSVDQNALHVVA--
MMAR_2605|M.marinum_M               AYTGNPLAHSFSLARYAGVLLGMSG----MPVTYSPGTVDQWPKNLSS--
MUL_1474|M.ulcerans_Agy99           VSGQMSIEAQYLANKLTKGFIGTKQIESNSRLCMAGASSGYKLSLGAD--
MAV_4535|M.avium_104                TSGQLFAEEYYTQAAIAHGAIGTNHVDGNTRLCTATAAEALKESFGCD--
                                                        :             : .:            

Mb1477|M.bovis_AF2122/97            LFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHPDRDYVGR
Rv1442|M.tuberculosis_H37Rv         LFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHPDRDYVGR
Mflv_3958|M.gilvum_PYR-GCK          HDDLFTRSTQWQVIVENTDTMVCFGGLALKNTAVNDGGTTAHPARDALNR
Mvan_2438|M.vanbaalenii_PYR-1       HDDLFKRSTQWDVIVEHTDLMVCFGGVALKNTGVNHGGTTAHPARGALDR
MSMEG_2738|M.smegmatis_MC2_155      HDDLFKRSTQWDVIVEHTGLMVCFGGMPLKNTGINDGGTSAHPMRDALRR
MAB_3041|M.abscessus_ATCC_1997      HDGLFKRSTSWDVIVENTDLLIAFGGIALKNTGVNHGGTTAHPARDALNR
TH_4483|M.thermoresistible__bu      -EAMYGSPIMVPVSDVDNCDYFLIVGANPAVSAWNWVESVPDGWRRALRR
MMAR_2605|M.marinum_M               -HLMYGGWWTFPVPDIERTDLLVIMGANPAAS---QGSLLAAPDVMGLID
MUL_1474|M.ulcerans_Agy99           -------GPPGSYQDFDHADVFLVIGAN--------MADCHPILFLRMME
MAV_4535|M.avium_104                -------GQPGSYTDVDHADVIALFGHN--------VAETQTVLWARMLD
                                                    .    . . *                     :  

Mb1477|M.bovis_AF2122/97            YRARGGR--LVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGLAY
Rv1442|M.tuberculosis_H37Rv         YRARGGR--LVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGLAY
Mflv_3958|M.gilvum_PYR-GCK          LRARGGR--IVSFSPLRDDV-------DGPCDWHAPVPGTDVAIMLALAH
Mvan_2438|M.vanbaalenii_PYR-1       FRARGGH--LVSFSPLRDDV-------DGPCDWFAPVPGTDVAIMLALAH
MSMEG_2738|M.smegmatis_MC2_155      FRGRGGR--IVSFSPLRDDV-------DGDCQWLALRPGTDVAVMLGLAY
MAB_3041|M.abscessus_ATCC_1997      FRDRGGR--IVSFSPLHDDI-------DGECEWHAPIPGTDVAVMLALAH
TH_4483|M.thermoresistible__bu      QR-AGAT--IVVVDPIRTET------ADRADIHLAVRPGQDWALLLAMVK
MMAR_2605|M.marinum_M               AIRQRGK--VIVIDPVRTVT------AARADEWLPIVPGTDAALLLAVAH
MUL_1474|M.ulcerans_Agy99           RVKSGAK--LIVVDPRRTAT------ADKADLFLQIAPGTDLALLNGLLH
MAV_4535|M.avium_104                RLAGSDPPAIVCVDPRLTPV------ARHATVHLAPLPGTNVALMNGLLH
                                             :: ..*                      ** : *:: .:  

Mb1477|M.bovis_AF2122/97            VLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLAAG
Rv1442|M.tuberculosis_H37Rv         VLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLAAG
Mflv_3958|M.gilvum_PYR-GCK          VLATESLADREFLASHCTGYDRFERYLLGADDGIPKSPQWASSLCGLSAD
Mvan_2438|M.vanbaalenii_PYR-1       VLAAESLADRDFLATYCTGYDRFERYLLGVDDGTPKSPQWAAQICGLDAD
MSMEG_2738|M.smegmatis_MC2_155      VLATEGLADREFLDTHCTGYERFERYLLGHDDGVAKSPEWAAHISGLSAD
MAB_3041|M.abscessus_ATCC_1997      VLAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPKSPEWAAPISGLDAA
TH_4483|M.thermoresistible__bu      IILDEGLEHRGDCTELATGVPRLRELVAAADLDD------LAARCDVPRT
MMAR_2605|M.marinum_M               TLFDEDLVN---PGPHVDGVDTMRRVAADWPPAR------VSAVTGIEEE
MUL_1474|M.ulcerans_Agy99           LIVENEQTDPQFISEFTEGWEVMPSFLEQFTPDR------VSEITGIPSE
MAV_4535|M.avium_104                EIIGNGWIDRDYIDAHSVGFDELQCRVSEFTPEW------VAEICGVAAT
                                     :  :   .         *   :                  :   .:   

Mb1477|M.bovis_AF2122/97            DLRDLARRMAEHRTLITTSLS-LQRIEHGEQTVWMAATLAAMLGQIGLPG
Rv1442|M.tuberculosis_H37Rv         DLRDLARRMAEHRTLITTSLS-LQRIEHGEQTVWMAATLAAMLGQIGLPG
Mflv_3958|M.gilvum_PYR-GCK          DLTALARRMAAGRTLVTVSWS-LQRTRHGEQAPWMGLTLAAMLGQIGLPG
Mvan_2438|M.vanbaalenii_PYR-1       DLTALARRMAACRTIVTVSWS-LQRTRHGEQAPWMGLTLAAMLGQIGLPG
MSMEG_2738|M.smegmatis_MC2_155      TLRALAHRMAAERTIVTVSWS-LQRTRHGEQAPWMGVTLAAMLGQIGLPG
MAB_3041|M.abscessus_ATCC_1997      ELRTLARRMAAGRTLVTVSWS-LQRVRHGEQAPWMGLTLAAMLGQIGLPG
TH_4483|M.thermoresistible__bu      QIERVARGFATARTAMAVTRTGVSLHATGTVGEWLGHVLNVITGRMDRPG
MMAR_2605|M.marinum_M               RIRRLARELAGTHKSVVYGRIGLCNQEFGSLASWLVDVINILTGHFDTPG
MUL_1474|M.ulcerans_Agy99           DIRTAARWIGTAANWMSCWTMGLNQSTHGTWNTNALCNLHLATGAICRPG
MAV_4535|M.avium_104                DLRRAARLIGTAQRLLSTVLQGFYQSHQATAAAVQVNNIHLVRGMLGRPG
                                     :   *: :.     :      .     .         :    * :  **

Mb1477|M.bovis_AF2122/97            GG-FGHGY-SSNGVGNPPLACG-------LPALPQGNNPVSTFIPVAAIS
Rv1442|M.tuberculosis_H37Rv         GG-FGHGY-SSNGVGNPPLACG-------LPALPQGNNPVSTFIPVAAIS
Mflv_3958|M.gilvum_PYR-GCK          GG-FGHGYGSMNEAGLAPIRCG-------LPRLPQGVNPVTTFIPVAAVS
Mvan_2438|M.vanbaalenii_PYR-1       GG-FGHGYGSMNEPGLAPVRCG-------LPRLPQGINPVTTFIPVAAVS
MSMEG_2738|M.smegmatis_MC2_155      GG-FGHGYGSMNEPGLAPLRCR-------LPSLPQGPNPVRTFIPVAAVT
MAB_3041|M.abscessus_ATCC_1997      GG-FGHGYGSMNEPGLAPVSCP-------LPTFPQGPNPVETFIPVAAIS
TH_4483|M.thermoresistible__bu      GRRFERGYVDAQRLTALVKPPA-------HRSRVHGRPMVAGAHALAELP
MMAR_2605|M.marinum_M               GAMFPRPAAWSITTQPLPGLEGGVAEFGRWHTRVRGAKEVLGQAPVSCLA
MUL_1474|M.ulcerans_Agy99           SGPFSLTGQPNAMGGREMGYMG---------PGLPGQRSVLSAPDREFVE
MAV_4535|M.avium_104                CGVLQMNGQPTAENTRECGADG----------DLAGFRNWSNDSHVAELA
                                       :                               *            : 

Mb1477|M.bovis_AF2122/97            ELLQRPGQRLAYNGR---------LLELPDIKCVYWAGGNPFHHHQNLPR
Rv1442|M.tuberculosis_H37Rv         ELLQRPGQRLAYNGR---------LLELPDIKCVYWAGGNPFHHHQNLPR
Mflv_3958|M.gilvum_PYR-GCK          DMLLHPGEPFDYNGL---------RLTYPDIRLVYWAGGNPFHHHQNLPR
Mvan_2438|M.vanbaalenii_PYR-1       DMLLSPGEPFDYNGL---------RLHYPDIRLVYWAGGNPFHHHQNIPR
MSMEG_2738|M.smegmatis_MC2_155      DMLLHPGEPFDYNGL---------RLTYPDIKCVYWSGGNPFHHHQNIPR
MAB_3041|M.abscessus_ATCC_1997      ELLLRPGQTLAYNGQ---------TLTLPDIRCVYWAGGNPFHHHQNLPR
TH_4483|M.thermoresistible__bu      DEITTPGP--------------------GRIRALVINSGNPVVSGPDGAR
MMAR_2605|M.marinum_M               EEIATPGD--------------------GQLRALITIAGNPVLSTPGGDK
MUL_1474|M.ulcerans_Agy99           EQWGLPGGALRTDVSGGVIDMFS-RMADGEIKACWIICSNPVATVANRKT
MAV_4535|M.avium_104                DLWNLEPLQIPHYGPPTHAMQMFRFAEEGTLRMLWVTATNPAVSLPELPR
                                    :                             ::       **         

Mb1477|M.bovis_AF2122/97            LRRALSRVDTIVVHEQYWT-AMAKHADIVVPTTTSFERDDFAASKT----
Rv1442|M.tuberculosis_H37Rv         LRRALSRVDTIVVHEQYWT-AMAKHADIVVPTTTSFERDDFAASKT----
Mflv_3958|M.gilvum_PYR-GCK          LRRALSRPDTVVVHDPYWT-AMAKHADIVVPSTTFAERDDLSGSRN----
Mvan_2438|M.vanbaalenii_PYR-1       LRRALRRPDTVVVHDPYWT-PMAKHADIVVPSTTFAERHDFSGSRN----
MSMEG_2738|M.smegmatis_MC2_155      LRRALGRVDTIVVHDPYWT-AMAKHADIVVPSTTSFERNDFSGSKN----
MAB_3041|M.abscessus_ATCC_1997      LRRALSRVDTVVVHDPVWT-AMAKHADIVVPSTTSLERDDFSGSRN----
TH_4483|M.thermoresistible__bu      LDAALAQLDLLVAIDLVQR-ESHRHAHWLLPAVHWLERDDLLALTSGMHD
MMAR_2605|M.marinum_M               LDEALSSLEAMISVDLWLN-ETTRHADVILPGLSPLEQPHHDDLVLQFAI
MUL_1474|M.ulcerans_Agy99           VLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDGVMVNCER---
MAV_4535|M.avium_104                IRDILSQQRLFLVVQDIFLTETAALADVVLPAAAWAEKTGTFTNADR---
                                    :   *     .:  :          *. ::*     *             

Mb1477|M.bovis_AF2122/97            NPTLIAMPAMVPPYANARDDYHTFSALAHRLGFGKQFTEGRSAREWLEHM
Rv1442|M.tuberculosis_H37Rv         NPTLIAMPAMVPPYANARDDYHTFSALAHRLGFGKQFTEGRSAREWLEHM
Mflv_3958|M.gilvum_PYR-GCK          DPMLMAMPRLTETYAQARDDYDTYAALAGHLGVRQAFTEGRSSRQWLRHI
Mvan_2438|M.vanbaalenii_PYR-1       DPVLMAMRRLAEPYAQARDDYDTFAALARRLGVADTFTEGRTSAQWLRHL
MSMEG_2738|M.smegmatis_MC2_155      DPLLVAMPQLAEPYADSRDDYTTFSALAERLGFGEQFTEGRTAWEWLVHL
MAB_3041|M.abscessus_ATCC_1997      DPLLVAMKAVAPPYANSRDDYTTFSALADRLGFGEQFSEGRTAAQWLRHI
TH_4483|M.thermoresistible__bu      EPYAQYGVRAVDPPPRAREEWRIFVDLALAMGRPLFGVRGINEFVTATRW
MMAR_2605|M.marinum_M               RSFANYSAPVFDPGDRPHEWEILIRLTGLCTGTPAEDVDVAAIDDGFFDY
MUL_1474|M.ulcerans_Agy99           --NMSLFPKAVDPVGDALPDWQIIARIACEMGFSESFSYS-SAAEVFEEI
MAV_4535|M.avium_104                --TVHLSEKAVEPPGSARSDLEIFLDYARRMDFRDKDGRPFPPWTDPESA
                                                .   .          .   .                  

Mb1477|M.bovis_AF2122/97            YDKWSAELD---FPVP--SFAEFWRTGRLELPTRTGLTWLADFRA----D
Rv1442|M.tuberculosis_H37Rv         YDKWSAELD---FPVP--SFAEFWRTGRLELPTRTGLTWLADFRA----D
Mflv_3958|M.gilvum_PYR-GCK          YETWSRTLD---FDVP--AFDGFWAAGALRLPTDDGLTLLADFRA----D
Mvan_2438|M.vanbaalenii_PYR-1       YEKWSATLD---FEVP--SFDEFWQVGQVRLPTDEGLTLFADFRA----D
MSMEG_2738|M.smegmatis_MC2_155      YEKWAAGLD---FAVP--SFAEFWAAGHVELPTDTGLTLFEDFRA----D
MAB_3041|M.abscessus_ATCC_1997      YTEWAGALN---FSVP--SFDEFWDRGYLELPTDAGLTLLSDFRE----N
TH_4483|M.thermoresistible__bu      LALRTGRPG---VAFG--PHWLDRLMVATSRKINGHRLTWRDLRE----H
MMAR_2605|M.marinum_M               LAFTKGFDG---AAIR--KRYEHDGWAGGPERILDLTLRTGPFGDRYGQN
MUL_1474|M.ulcerans_Agy99           KRFSNPATG---YDLRGISHDRLRETPLQWPCPPDGASNRSPIRY-----
MAV_4535|M.avium_104                FEAWKKCSAGRPCDYTGLSYAKLRGGSGIQWPCNTDHPDGIERLYEDGRF
                                                                                      

Mb1477|M.bovis_AF2122/97            PAAHPLGTPSGRIEIFSDTVDAFALPDCAGHPTWYEPS-------EWLGG
Rv1442|M.tuberculosis_H37Rv         PAAHPLGTPSGRIEIFSDTVDAFALPDCAGHPTWYEPS-------EWLGG
Mflv_3958|M.gilvum_PYR-GCK          PSAHPLATPSGRIEIFSADIDSFGYDDCRGHPAWFEPT-------EWLGG
Mvan_2438|M.vanbaalenii_PYR-1       PSAHRLATPSGRIEIFSADIAGFGYRDCVGHPAWFEPA-------EWLGG
MSMEG_2738|M.smegmatis_MC2_155      PQAHPLGTPSGRIEIFSEDIDSFGYDDCAGHPRWYEPA-------EWLGG
MAB_3041|M.abscessus_ATCC_1997      PAAHPLHTPSGRIEIFSETIDGFGYSDCGGHPQWYEPT-------EWLGG
TH_4483|M.thermoresistible__bu      PHGLVLGPRE--FGHFRSALRTPDKKVHTAPPEFIARVR------ELLAE
MMAR_2605|M.marinum_M               PGGLTLDMLKANPNGIDFGPMVSQLPDILGTPEKKIRLAPQYLLDDLPRL
MUL_1474|M.ulcerans_Agy99           ---LNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARP-------HLVPD
MAV_4535|M.avium_104                PAAPDYCEAYGKDLITGAPLQPDEYRSLNPSGKAIIKAAQ-----YLPPH
                                                                                      

Mb1477|M.bovis_AF2122/97            PRAARYPLHLIANQPRTRLHSQLDHGGASMASKIRGRE-PIRIHPDDAAA
Rv1442|M.tuberculosis_H37Rv         PRAARYPLHLIANQPRTRLHSQLDHGGASMASKIRGRE-PIRIHPDDAAA
Mflv_3958|M.gilvum_PYR-GCK          PRAADYPLHLVANQPAGRLHGQLDAGAASQATKVAGRE-PIRMHPADAHA
Mvan_2438|M.vanbaalenii_PYR-1       PRAERYPLHLLANQPASRLHSQLDGGATSQASKVAGRE-PVRMHPDDAAE
MSMEG_2738|M.smegmatis_MC2_155      ERARRYPLHLLANQPASRLHSQLDGGATSQSSKVQGRE-PVRMHPSDAAA
MAB_3041|M.abscessus_ATCC_1997      ERAQRFPLHLIANQPRTRLHSQLDFGGTSQGSKVRGRE-PLRIHPQDAAT
TH_4483|M.thermoresistible__bu      PHPQAPPGYPFVLGNRRRRHSMNSWLNELPDLHPGGRQNTAILHPDDAAT
MMAR_2605|M.marinum_M               ASRMDRPAEQLVLVNRRHLRSNNSWLHNVPALMKGKDRCTLLMHPDDAAR
MUL_1474|M.ulcerans_Agy99           EMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAAD
MAV_4535|M.avium_104                ERPGPDYPFALITGRTIYHFHTRTKTARAQQLQDAAPEVWVEVSERDARR
                                              .                               :   **  

Mb1477|M.bovis_AF2122/97            RELTDGDIVRVFNDRGACLAGVVIDDGLRPK-------------------
Rv1442|M.tuberculosis_H37Rv         RELTDGDIVRVFNDRGACLAGVVIDDGLRPK-------------------
Mflv_3958|M.gilvum_PYR-GCK          RDLSGGDVVRVFNDRGACLAGVVLDDRVRPQ-------------------
Mvan_2438|M.vanbaalenii_PYR-1       RGLAAGDVVRMFNDSGACLAGVVLDDRVRPR-------------------
MSMEG_2738|M.smegmatis_MC2_155      RGLADGDVVRVFNDRGACLAGVVIDDGVLPR-------------------
MAB_3041|M.abscessus_ATCC_1997      RGIADGDVVRVFNDRGACLAGAVLDEGLRRQ-------------------
TH_4483|M.thermoresistible__bu      LGIADGDRVRLSSPVGVVEAEANLSDRPRRG-------------------
MMAR_2605|M.marinum_M               NGITDNDTVTVRSSAGEITVPVELTSAIKPG-------------------
MUL_1474|M.ulcerans_Agy99           MQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSIN
MAV_4535|M.avium_104                LGIEAGDLVHVSTPRGRITCAARVG-GIRDG-------------------
                                      :  .* : : .  *     . :                          

Mb1477|M.bovis_AF2122/97            --------------------VVQLSTGAWFDPADPRDPDSMCVHGNPNAL
Rv1442|M.tuberculosis_H37Rv         --------------------VVQLSTGAWFDPADPRDPDSMCVHGNPNAL
Mflv_3958|M.gilvum_PYR-GCK          --------------------VVQLSTGAWFDPADPADPHSMCVHGNPNVL
Mvan_2438|M.vanbaalenii_PYR-1       --------------------VVQLSTGAWFDPADPADPDSMCVHGNPNML
MSMEG_2738|M.smegmatis_MC2_155      --------------------VVQLATGAWYDPADPADPDSLCLHGNPNVL
MAB_3041|M.abscessus_ATCC_1997      --------------------VVQLSTGAWFDPIEPADPNSACAHGNPNVL
TH_4483|M.thermoresistible__bu      --------------------LVILDHGWGSRVFDPSGHHPPQSYGVNRNL
MMAR_2605|M.marinum_M               --------------------VVSMPHGWGHG---KPGTRLAVANSAPGVN
MUL_1474|M.ulcerans_Agy99           AVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADACADATAPKL
MAV_4535|M.avium_104                --------------------VLFVPFHYGYWDRDGGDHQRAGNELTATDW
                                                        :                             

Mb1477|M.bovis_AF2122/97            SNDSGTSSLAHGSTGQHVLVQIERFTGELPPVRAHEPPRLA---------
Rv1442|M.tuberculosis_H37Rv         SNDSGTSSLAHGSTGQHVLVQIERFTGELPPVRAHEPPRLA---------
Mflv_3958|M.gilvum_PYR-GCK          TDDVGTSKLAHGCTGAHVLVQIEKYAGTPPPVRAHQPPVFTPR-------
Mvan_2438|M.vanbaalenii_PYR-1       TDDVGTSALAHGCTGAHALVQIEKYTAAPPPVRAHQPPVFAAR-------
MSMEG_2738|M.smegmatis_MC2_155      TDDVGTSSLAKGCTGAHVLVEIEKFAGPVPPVRAHEPPVIRTLR------
MAB_3041|M.abscessus_ATCC_1997      TDDSGTSSLAQGCTGQHVLVQIERFEGTPPPVRAHTPPRFVARD------
TH_4483|M.thermoresistible__bu      LVDASIDPLSQTSTLGTANVAIERSGA-----------------------
MMAR_2605|M.marinum_M               TNVLSPPTLLDEPSGNGVLNGIPVTVS-----------------------
MUL_1474|M.ulcerans_Agy99           LADTAQFSVTQVDALAELLGVGNEPTPQFGPSARSYLAGLIAGLRSETGR
MAV_4535|M.avium_104                DPASKQPSFKTAAARLDMAPTHTAAPVSEAVAAGSPS-------------
                                            .    :                                    

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           RMAGVSTLPISSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQ
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           SDNAAEAAVEQPPIVVLWASQTGTAEELAASVAAQLSAAELPVVLHGMDE
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           FAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAPTAPSLAGTRYSV
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           LALGDSNYADFCGHGRALDHRLAELGASRITDRVDCEPDYEESAARWLQE
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           VLDGLRRTAPPVITAEPVRAASIASRPQGYTKKRPLLTSVMRNTTLSRPR
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           SAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQLVDEWLGVTRLDGHTE
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           VEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQRTLDSNTANQLAELMR
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           PENKAALADWTWGRQSVDLLAQSPVRASVDEWMSVLKPIQPRLYSISSSP
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           KEHPGEVHLTVSPVRYNFQGVPRRGVCSTYLADRSPSDQIAIYVRKSSNF
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           RPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGHTGPNWLFFGEQHAATD
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           FYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVYVQHLMQQRGAQLWQWLQD
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            --------------------------------------------------
Rv1442|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_3958|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2438|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2738|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4483|M.thermoresistible__bu      --------------------------------------------------
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_1474|M.ulcerans_Agy99           GAQVYVCGTADPMAKDVDRMLCQIVAEHGGLDPESATAFVHALSADKRYH
MAV_4535|M.avium_104                --------------------------------------------------
                                                                                      

Mb1477|M.bovis_AF2122/97            ----
Rv1442|M.tuberculosis_H37Rv         ----
Mflv_3958|M.gilvum_PYR-GCK          ----
Mvan_2438|M.vanbaalenii_PYR-1       ----
MSMEG_2738|M.smegmatis_MC2_155      ----
MAB_3041|M.abscessus_ATCC_1997      ----
TH_4483|M.thermoresistible__bu      ----
MMAR_2605|M.marinum_M               ----
MUL_1474|M.ulcerans_Agy99           RDVY
MAV_4535|M.avium_104                ----