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VATDRIANPWGTRTPYAPGTRWPERIDTYLADGVTAESVDRWVQSAAVLHSNGDGLDIAVKDGRIVGVRG RAVDRVNHGRLDPKDLFGWQANASADRLTTPLLRVRGALRPCDWDTAMERIVARSRELLDRHGPSSIGFY TSGQLFAEEYYTQAAIAHGAIGTNHVDGNTRLCTATAAEALKESFGCDGQPGSYTDVDHADVIALFGHNV AETQTVLWARMLDRLAGSDPPAIVCVDPRLTPVARHATVHLAPLPGTNVALMNGLLHEIIGNGWIDRDYI DAHSVGFDELQCRVSEFTPEWVAEICGVAATDLRRAARLIGTAQRLLSTVLQGFYQSHQATAAAVQVNNI HLVRGMLGRPGCGVLQMNGQPTAENTRECGADGDLAGFRNWSNDSHVAELADLWNLEPLQIPHYGPPTHA MQMFRFAEEGTLRMLWVTATNPAVSLPELPRIRDILSQQRLFLVVQDIFLTETAALADVVLPAAAWAEKT GTFTNADRTVHLSEKAVEPPGSARSDLEIFLDYARRMDFRDKDGRPFPPWTDPESAFEAWKKCSAGRPCD YTGLSYAKLRGGSGIQWPCNTDHPDGIERLYEDGRFPAAPDYCEAYGKDLITGAPLQPDEYRSLNPSGKA IIKAAQYLPPHERPGPDYPFALITGRTIYHFHTRTKTARAQQLQDAAPEVWVEVSERDARRLGIEAGDLV HVSTPRGRITCAARVGGIRDGVLFVPFHYGYWDRDGGDHQRAGNELTATDWDPASKQPSFKTAAARLDMA PTHTAAPVSEAVAAGSPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4535 | - | - | 100% (788) | nitrate reductase NarB |
| M. avium 104 | MAV_2075 | - | e-100 | 34.06% (731) | FdhF protein |
| M. avium 104 | MAV_4983 | - | 9e-25 | 24.38% (771) | molybdopterin oxidoreductase Fe4S4 subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2924c | fdhF | 5e-22 | 27.03% (296) | formate dehydrogenase H |
| M. gilvum PYR-GCK | Mflv_3016 | - | 4e-96 | 33.56% (721) | molybdopterin oxidoreductase |
| M. tuberculosis H37Rv | Rv2900c | fdhF | 5e-22 | 27.03% (296) | formate dehydrogenase H |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2438 | - | 1e-103 | 35.89% (716) | oxidoreductase |
| M. marinum M | MMAR_3639 | fdhF | 2e-92 | 32.91% (714) | formate dehydrogenase H FdhF |
| M. smegmatis MC2 155 | MSMEG_2837 | - | 0.0 | 78.55% (788) | nitrate reductase NarB |
| M. thermoresistible (build 8) | TH_4483 | - | 3e-28 | 25.64% (776) | PUTATIVE Formate dehydrogenase |
| M. ulcerans Agy99 | MUL_1474 | fdhF | 8e-92 | 32.77% (714) | formate dehydrogenase H FdhF |
| M. vanbaalenii PYR-1 | Mvan_3491 | - | 1e-102 | 34.66% (730) | molybdopterin oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4535|M.avium_104 ------------MATDRIANPWGTRTPYAPGTRWPERIDTYLADGVTAES
MSMEG_2837|M.smegmatis_MC2_155 -----------MARTDRISDPWGSRTPYAAGEPWPQRVDRYLTPGLTDDD
MMAR_3639|M.marinum_M ----------------------------------------MAPNKDAVKT
MUL_1474|M.ulcerans_Agy99 ----------------------------------------MAPNKDAVKT
Mflv_3016|M.gilvum_PYR-GCK ----------------------------------------------MTRT
Mvan_3491|M.vanbaalenii_PYR-1 ----------------------------------------------MTRT
MAB_2438|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2924c|M.bovis_AF2122/97 MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQ
Rv2900c|M.tuberculosis_H37Rv MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQ
TH_4483|M.thermoresistible__bu --------------------------------------------MTTVHT
MAV_4535|M.avium_104 VDRWVQSAAVLHSNGD------------GLDIAVKDGRIVGVRGRAVDRV
MSMEG_2837|M.smegmatis_MC2_155 VDRWVQSAAVLHSNGD------------GLDIAVKDGRIVGVRGRADDRV
MMAR_3639|M.marinum_M VCAYCGVGCGIVLQTT------------TDP-QTGKRRVAKSTGDKSHPA
MUL_1474|M.ulcerans_Agy99 VCAYCGVGCGIVLQTT------------TDP-QTGKRRVAKSTGDKSHPA
Mflv_3016|M.gilvum_PYR-GCK ACSYCGVGCGISVETR------------TDP-ASGVPVIARVSGDKLHPT
Mvan_3491|M.vanbaalenii_PYR-1 ACSYCGVGCGISVETR------------TDP-ATGVPVIARVTGDKLHPS
MAB_2438|M.abscessus_ATCC_1997 --------------MR------------TDAHAAGPVTVATVEGDVLHPS
Mb2924c|M.bovis_AF2122/97 QMGALRTAAALARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEE
Rv2900c|M.tuberculosis_H37Rv QMGALRTAAALARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEE
TH_4483|M.thermoresistible__bu FCRYCLAACGVEVTVE-------------------DNRVVNISADRANPH
. .
MAV_4535|M.avium_104 NHGRLDPKDLFGWQANAS-----------ADRLTTPLLR--VRGALRPCD
MSMEG_2837|M.smegmatis_MC2_155 NHGRLDPKDLFGWQANHA-----------RDRLRTPLIR--QDGVLVESD
MMAR_3639|M.marinum_M NLGRLCTKGTTTADLLAA-----------PGRMESAHLRAHRAGHLESIP
MUL_1474|M.ulcerans_Agy99 NLGRLCTKGTTTADLLAA-----------PGRMESAHLRAHRAGHLESIP
Mflv_3016|M.gilvum_PYR-GCK NFGRLCTKGATHAEMMAAT----------DGRLTTALVRPSRDADPVALD
Mvan_3491|M.vanbaalenii_PYR-1 NFGRLCTKGATHAEMMAAT----------DGRLTTALLRPSRDAEPVATD
MAB_2438|M.abscessus_ATCC_1997 NQGRLCTKGATHAQLMAA-----------DGRMTTAHLRSIRGQQPIPAP
Mb2924c|M.bovis_AF2122/97 ATKRTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPIS
Rv2900c|M.tuberculosis_H37Rv ATKRTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPIS
TH_4483|M.thermoresistible__bu TWHDFCAKGRTAHQVVEHP-----------RRILAPMRR--VGDRYVEAD
. . *: .
MAV_4535|M.avium_104 WDTAMERIVARSRELLDRHGPSSIGFYTSGQLFAEEYYTQAAIAHGAIGT
MSMEG_2837|M.smegmatis_MC2_155 WDTAMDRIVARSRQLLDERGPNSIGFYTSGQLFLEEYYTQCVIAHGAIGT
MMAR_3639|M.marinum_M IDDAITQCAMRLRAIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGT
MUL_1474|M.ulcerans_Agy99 IDDAITQCAMRLRAIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGT
Mflv_3016|M.gilvum_PYR-GCK VDDAVAEAGSRLRAIVDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRT
Mvan_3491|M.vanbaalenii_PYR-1 VDDALAEAGARLRAILDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRT
MAB_2438|M.abscessus_ATCC_1997 LAAATAEAGRRLREILDNHGPDAIALYVSGQMTLEAQYLANKLAKGYIRT
Mb2924c|M.bovis_AF2122/97 WDAAYQLIAEQLNGLDS---PDRAVFYTSGRTSNEAAFCYQLLVR-SFGT
Rv2900c|M.tuberculosis_H37Rv WDAAYQLIAEQLNGLDS---PDRAVFYTSGRTSNEAAFCYQLLVR-SFGT
TH_4483|M.thermoresistible__bu WDEAITDIATRLNALIDADGPDAIGLYYGNPTGYSTSNLIFMNAWLDAVG
* : . : . *. .* .. . .
MAV_4535|M.avium_104 NHVDGNTRLCTATAAEALKESFGCDGQPGSYTDVDHADVIALFGH-----
MSMEG_2837|M.smegmatis_MC2_155 NHVDGNTRLCTATAAEALKESFGCDGQPGSYTDVDHADVIALYGH-----
MMAR_3639|M.marinum_M NQIESNSRLCMAGASSGYKLSLGADGPPGSYQDFDHADVFLVIGA-----
MUL_1474|M.ulcerans_Agy99 KQIESNSRLCMAGASSGYKLSLGADGPPGSYQDFDHADVFLVIGA-----
Mflv_3016|M.gilvum_PYR-GCK VHIESNSRLCMASAGTGYKQSLGSDGPPGSYTDFDCTNLFFVIGS-----
Mvan_3491|M.vanbaalenii_PYR-1 VHIESNSRLCMASAGTGFKQSLGADGPPGSYTDFDCTDLFFVIGS-----
MAB_2438|M.abscessus_ATCC_1997 THIESNSRLCMASAGTGYAQSLGADGPPGSYSDIEHSDLFFVIGA-----
Mb2924c|M.bovis_AF2122/97 NNLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAGQ-----
Rv2900c|M.tuberculosis_H37Rv NNLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAGQ-----
TH_4483|M.thermoresistible__bu TNNRYAVGSVDQNALHVVAEAMYGSPIMVPVSDVDNCDYFLIVGANPAVS
: : :: . . *.: : : : *
MAV_4535|M.avium_104 --NVAETQTVLWARMLDRLAGSDPPAIVCVDPRLTP--------------
MSMEG_2837|M.smegmatis_MC2_155 --NVAETQTVLWMRMLDRLAGPNPPAIVCIDPRPTP--------------
MMAR_3639|M.marinum_M --NMADCHPILFLRMMERVKSG--AKLIVVDPRRTA--------------
MUL_1474|M.ulcerans_Agy99 --NMADCHPILFLRMMERVKSG--AKLIVVDPRRTA--------------
Mflv_3016|M.gilvum_PYR-GCK --NMADCHPILYLRMADRLKAG--ARLIVVDPRRTA--------------
Mvan_3491|M.vanbaalenii_PYR-1 --NMADCHPILYLRMADRLKAG--AKLIVVDPRRTA--------------
MAB_2438|M.abscessus_ATCC_1997 --NMADCHPILFLRMADRLSSG--ARLIVVDPRRTA--------------
Mb2924c|M.bovis_AF2122/97 --NPGTNHPRMLSVLGKAKANG--AKIIAVNPLPEAGLIRFKDPQKVNGV
Rv2900c|M.tuberculosis_H37Rv --NPGTNHPRMLSVLGKAKANG--AKIIAVNPLPEAGLIRFKDPQKVNGV
TH_4483|M.thermoresistible__bu AWNWVESVPDGWRRALRRQRAG--ATIVVVDPIRTE--------------
* . . :: ::*
MAV_4535|M.avium_104 ---VARHATVHLAPLPGTNVALMNGLLHEIIGNGW------IDRDYIDAH
MSMEG_2837|M.smegmatis_MC2_155 ---VARHATVHLAPLPGTNVALMNGLLHEILDHDW------MDHDYIEAH
MMAR_3639|M.marinum_M ---TADKADLFLQIAPGTDLALLNGLLHLIVENEQ------TDPQFISEF
MUL_1474|M.ulcerans_Agy99 ---TADKADLFLQIAPGTDLALLNGLLHLIVENEQ------TDPQFISEF
Mflv_3016|M.gilvum_PYR-GCK ---TADKADLYLPIRPGTDLALLNGILRVLVQDGA------IDEAFIAEH
Mvan_3491|M.vanbaalenii_PYR-1 ---TADKADLYLPIRPGTDLALLNGILHLLVENGA------VDQEFIAEH
MAB_2438|M.abscessus_ATCC_1997 ---TADRADLFLQITPGTDLALLNGLLHLLVENGA------VDAEFIAQH
Mb2924c|M.bovis_AF2122/97 VGHGIPIADEFVQIRLGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNH
Rv2900c|M.tuberculosis_H37Rv VGHGIPIADEFVQIRLGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNH
TH_4483|M.thermoresistible__bu ---TADRADIHLAVRPGQDWALLLAMVKIILDEGL------EHRGDCTEL
* .: * : **: .: : :: .
MAV_4535|M.avium_104 SVGFDELQCRVSEFTPEWVAEICGVAATDLRRAARLIGTAQRLLSTVLQG
MSMEG_2837|M.smegmatis_MC2_155 TVGFHELRKRVAEFPPERVADICGVDPDDVRRAGELIGTAERLLSTVLQG
MMAR_3639|M.marinum_M TEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWMSCWTMG
MUL_1474|M.ulcerans_Agy99 TEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWMSCWTMG
Mflv_3016|M.gilvum_PYR-GCK TEGWEAMPAFLADYPPSRVAEITGLAEADIRSAAAMIAEAGDWISCWTMG
Mvan_3491|M.vanbaalenii_PYR-1 TQGWESMPEFLAGYPPDRVAAITGLSEADIRAAADMIAEAGDWLSCWTMG
MAB_2438|M.abscessus_ATCC_1997 TEGWDGMPEFLAGYAPAVVAAITGLAEEDIRTAARWIGEAREWMTLWTMG
Mb2924c|M.bovis_AF2122/97 CAGFDGYRRRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMG
Rv2900c|M.tuberculosis_H37Rv CAGFDGYRRRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMG
TH_4483|M.thermoresistible__bu ATGVPRLRELVAAADLDDLAARCDVPRTQIERVARGFATARTAMAVTRTG
* : .: ::. .. : : : *
MAV_4535|M.avium_104 FYQSHQATAAAVQVNNIHLVRGMLGRPGCGVLQMNGQPTAENTRECGADG
MSMEG_2837|M.smegmatis_MC2_155 FYQSHQATAAAVQVNNIHLVRGMLGRPGCGLLQMNGQPTAENTRECGADG
MMAR_3639|M.marinum_M LNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMG
MUL_1474|M.ulcerans_Agy99 LNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMG
Mflv_3016|M.gilvum_PYR-GCK LNQSTHGTWNTNAICNLHLATGAICRPGAGPMSLTGQPNAMGGREMGYMG
Mvan_3491|M.vanbaalenii_PYR-1 LNQSTHGTWNTNAICNLHLATGAICRPGSGPMSLTGQPNAMGGREMGYMG
MAB_2438|M.abscessus_ATCC_1997 LNQSTHGTWNTNAICNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMG
Mb2924c|M.bovis_AF2122/97 LTQHAHAVATIGEVTNVLLLRGMIGKPGAGVCPVRGHSNVQGDR------
Rv2900c|M.tuberculosis_H37Rv LTQHAHAVATIGEVTNVLLLRGMIGKPGAGVCPVRGHSNVQGDR------
TH_4483|M.thermoresistible__bu VSLHATGTVGEWLGHVLNVITGRMDRPGGRRFER-GYVDAQRLT------
. .. : : * : :** * .
MAV_4535|M.avium_104 -DLAGFRNWSNDSHVAELADLWNLEPLQIPHYGPPTHAMQMFRFAEEGTL
MSMEG_2837|M.smegmatis_MC2_155 -DLAGFRNWANDSHIEELATLWNLDVTAIPHYAPPTHAMQMFRYAEEGSL
MMAR_3639|M.marinum_M PGLPGQRSVLSAPDREFVEEQWGLPGGALRTDVS-GGVIDMFSRMADGEI
MUL_1474|M.ulcerans_Agy99 PGLPGQRSVLSAPDREFVEEQWGLPGGALRTDVS-GGVIDMFSRMADGEI
Mflv_3016|M.gilvum_PYR-GCK PGLPGQRAVLSAEDRSFVETQWDLEPGTVRTEVG-PGTVEMFRRIAGGDI
Mvan_3491|M.vanbaalenii_PYR-1 PGLPGQRSVASAADRAFVEEQWDLEPGTIRADIG-PGTVEMFRQMGSGDI
MAB_2438|M.abscessus_ATCC_1997 PGLPGQRSVKSPADRDFVEKRWQLPPGSIRAEFG-TGTVDMFAQMAAGNI
Mb2924c|M.bovis_AF2122/97 --TMGIWEKMPEQFLAALDREFGITSPRAHGFDT----VAAIRAMRDGRV
Rv2900c|M.tuberculosis_H37Rv --TMGIWEKMPEQFLAALDREFGITSPRAHGFDT----VAAIRAMRDGRV
TH_4483|M.thermoresistible__bu ------ALVKPPAHRSRVHGRPMVAGAHALAELP-----DEITTPGPGRI
: : : * :
MAV_4535|M.avium_104 RMLWVTATNPAVSLPELPRIRDILSQQRLFLVVQDIFLTETAALADVVLP
MSMEG_2837|M.smegmatis_MC2_155 RMLWVSATNPAVSLPELGRIRRILSQDRLFLVVQDLFLTETAQLADVVLP
MMAR_3639|M.marinum_M KACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNEYANVLLP
MUL_1474|M.ulcerans_Agy99 KACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNEYANVLLP
Mflv_3016|M.gilvum_PYR-GCK KAVWIICTNPVASVANRDTVITGLQSAELVITQDAYVDTATNRYADIMLP
Mvan_3491|M.vanbaalenii_PYR-1 KAAWIICTNPVASVANRDAVVAGLSTAELVITQDVYADTATNRYADIVLP
MAB_2438|M.abscessus_ATCC_1997 KACWIICTNPVASVANRKNVVDGLRRAELVIAQDAFLATATNEYADILLP
Mb2924c|M.bovis_AF2122/97 SVFMGMGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALI
Rv2900c|M.tuberculosis_H37Rv SVFMGMGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALI
TH_4483|M.thermoresistible__bu RALVINSGNPVVSGPDGARLDAALAQLDLLVAID-LVQRESHRHAHWLLP
* . : .: * * : . . *
MAV_4535|M.avium_104 AAAWAEKT-----GTFTNADRTVHLSEKAVEPPGSARSDLEIFLDYARRM
MSMEG_2837|M.smegmatis_MC2_155 AAAWAEKT-----GTFTNADRTVHISDKAVDPPGQARSDFDIFLDYARRM
MMAR_3639|M.marinum_M AALWTESD-----GVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEM
MUL_1474|M.ulcerans_Agy99 AALWTESD-----GVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEM
Mflv_3016|M.gilvum_PYR-GCK ATLWAEAD-----AVMVNSGRTLTLLAQSVPAAGDARPDWELICGVARHL
Mvan_3491|M.vanbaalenii_PYR-1 ATLWAETD-----AVMVNSDRNLTLLQQSVPPVGDARPDWELICGVARHL
MAB_2438|M.abscessus_ATCC_1997 AALWAESD-----GVSINSERTATLTNRAVEAPGDARPDWQLICDIATAM
Mb2924c|M.bovis_AF2122/97 LPTLGRTD-----RDTRNGRKQLVSVEDSMSMVHLSRGSLHPPSDQVR--
Rv2900c|M.tuberculosis_H37Rv LPTLGRTD-----RDTRNGRKQLVSVEDSMSMVHLSRGSLHPPSDQVR--
TH_4483|M.thermoresistible__bu AVHWLERDDLLALTSGMHDEPYAQYGVRAVDPPPRAREEWRIFVDLALAM
. : :: : . .
MAV_4535|M.avium_104 DFRDKDGRPFPPWTDPESAFEAWKKCSAGRP-CDYTGLS--YAKLRGGSG
MSMEG_2837|M.smegmatis_MC2_155 DFRDRDGRPLPAWNTPDEAFEAWKRCSAGRP-CDYTGLS--YEKLRGSGG
MMAR_3639|M.marinum_M GFSESFS-----YSSAAEVFEEIKRFSNPATGYDLRGIS--HDRLRETP-
MUL_1474|M.ulcerans_Agy99 GFSESFS-----YSSAAEVFEEIKRFSNPATGYDLRGIS--HDRLRETP-
Mflv_3016|M.gilvum_PYR-GCK GFGDAFD-----HKSSEEIFDEIRRFHNPRTGYDLRGVT--YERLRATP-
Mvan_3491|M.vanbaalenii_PYR-1 GFGDAFD-----YKSSEQIFDEIRRFHNPGTGYDLRGIT--YERLRDTP-
MAB_2438|M.abscessus_ATCC_1997 GFGDAFG-----YSSSEEIFEEIRAFWNPRTGYDMRGMS--YARLRQGP-
Mb2924c|M.bovis_AF2122/97 -------------SEVQIICQLARALFGPGHPVPWERFADDYDTIRDAIA
Rv2900c|M.tuberculosis_H37Rv -------------SEVQIICQLARALFGPGHPVPWERFADDYDTIRDAIA
TH_4483|M.thermoresistible__bu G-RPLFG------VRGINEFVTATRWLALRTGRPGVAFGPHWLDRLMVAT
.
MAV_4535|M.avium_104 IQWPCNTDHPDGIERLYEDGRFPAAPDYCEAYGKDLITGAPLQPDEYRSL
MSMEG_2837|M.smegmatis_MC2_155 IQWPCNAEHPDGVERLYAGGEFFAAPDYCEAYGKDLITGAPLEPTEYRAM
MMAR_3639|M.marinum_M LQWPCPPDGASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPT--------
MUL_1474|M.ulcerans_Agy99 LQWPCPPDGASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPT--------
Mflv_3016|M.gilvum_PYR-GCK VQWPCPSEDAPDRNPIRYLNDGVSQDLHIDDDGHIPRLAFAT--------
Mvan_3491|M.vanbaalenii_PYR-1 VQWPCASAEQSDRNPIRYLNDGVSQDQYVGPDGHRPRLAFPT--------
MAB_2438|M.abscessus_ATCC_1997 VQWPCPPESEVDRNPIRYLNDGISQHPHVDENGVVPRLAFPT--------
Mb2924c|M.bovis_AF2122/97 AVVPGCDDYNHKVRVPDGFQLPHPPRDAREFRTSTGKANFAVN-------
Rv2900c|M.tuberculosis_H37Rv AVVPGCDDYNHKVRVPDGFQLPHPPRDAREFRTSTGKANFAVN-------
TH_4483|M.thermoresistible__bu SRKINGHRLTWRDLREHPHGLVLGPREFGHFRSALRTPDKKVHT------
MAV_4535|M.avium_104 NPSGKAIIKAAQYLPPHERPGPDYPFALITGRTIYHFHTRTKTARAQQLQ
MSMEG_2837|M.smegmatis_MC2_155 NPFGKAIIKAAEYVPPHERPSAEYPCVLITGRTVYHFHTRTKTGRTPQLQ
MMAR_3639|M.marinum_M -ATGRAVFFARPHLVPDEMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLN
MUL_1474|M.ulcerans_Agy99 -ATGRAVFFARPHLVPDEMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLN
Mflv_3016|M.gilvum_PYR-GCK -PSRRAVFHPRPHLDAAELPDDDYPFILNTGRLQHQWHTMTKTGRVAKLT
Mvan_3491|M.vanbaalenii_PYR-1 -PSRRAVFHPRPHMDAAELPDDDYPLVLNTGRLQHQWHTMTKTGKVAKLN
MAB_2438|M.abscessus_ATCC_1997 -PSRRAVFHARAHRDPAELPGEGYPVVLNTGRLQHHWHTLTKTGRIKTLD
Mb2924c|M.bovis_AF2122/97 -PLQWVPVPPGRLVLQTLRSHDQYNTTIYG--LDDRYRGVKGGRRVVFIN
Rv2900c|M.tuberculosis_H37Rv -PLQWVPVPPGRLVLQTLRSHDQYNTTIYG--LDDRYRGVKGGRRVVFIN
TH_4483|M.thermoresistible__bu APPEFIARVRELLAEPHPQAPPGYPFVLGNRRRRHSMNSWLN--ELPDLH
. . * : . . :
MAV_4535|M.avium_104 DAAPEVWVEVSERDARRLGIEAGDLVHVSTPRGRITCAARVGG-IRDGVL
MSMEG_2837|M.smegmatis_MC2_155 AAAPEVWVELARADALRAGIVEGDLVEIRTVRGCVTAAARLTD-LRRGVV
MMAR_3639|M.marinum_M KLNPGPFVEVHPDDAADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNC
MUL_1474|M.ulcerans_Agy99 KLNPGPFVEVHPDDAADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNC
Mflv_3016|M.gilvum_PYR-GCK KLNPAPFVEIHPSDAAALGITDGQDLELRTRRGRAVLPAVLTERVRPGNT
Mvan_3491|M.vanbaalenii_PYR-1 KLNPGPFVEIHPDDAAALGISGGHDVELVTRRGRAVLPAVLTDRVQPGNT
MAB_2438|M.abscessus_ATCC_1997 RLHPSPFVEIHPHDATTLGISDGDIVEIASRRGTAELPALVSDRVKRGSC
Mb2924c|M.bovis_AF2122/97 PADIETFGLTAGDRVDLVSEWTDGQGGLQERRAKDFLVVAYSTPVGNAAA
Rv2900c|M.tuberculosis_H37Rv PADIETFGLTAGDRVDLVSEWTDGQGGLQERRAKDFLVVAYSTPVGNAAA
TH_4483|M.thermoresistible__bu PGGRQNTAILHPDDAATLGIADGDRVRLSSPVGVVEAEANLSDRPRRGLV
. . : . . .
MAV_4535|M.avium_104 FVPFHYGYWDR--DGGD--HQRAGNELTATDWDPASKQPSFKTAAA----
MSMEG_2837|M.smegmatis_MC2_155 FLPFHYGYWDTGDDGGKDGHHRAANELTLTDWDPVSKQPIFKTAAAS---
MMAR_3639|M.marinum_M FAPFHWN--------DAFGEYLSINAVTNDAVDPISRQPEYKACAVTLTK
MUL_1474|M.ulcerans_Agy99 FAPFHWN--------DAFGEYLSINAVTNDAVDPISRQPEYKACAVTLTK
Mflv_3016|M.gilvum_PYR-GCK WAPFHWN--------DEHGENLTINALTNDAVDPDSLQPEFKVCAVRLTP
Mvan_3491|M.vanbaalenii_PYR-1 WVPFHWN--------DEHGDHLTVNALTNDAVDPDSLQPEFKVCAVRLAP
MAB_2438|M.abscessus_ATCC_1997 FAPFHWN--------DAHGPGLTINAVTNDAVDPDSLQPEFKVSAVALRP
Mb2924c|M.bovis_AF2122/97 YYPETNP-------------LVPLDHTAAQSNTPVSKAIIVRLEPTA---
Rv2900c|M.tuberculosis_H37Rv YYPETNP-------------LVPLDHTAAQSNTPVSKAIIVRLEPTA---
TH_4483|M.thermoresistible__bu ILDHGWG-------------SRVFDPSGHHPPQSYGVNRNLLVDAS----
: . . .
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M VARPQLQPEPGEPADTCADATAPKLLADTAQFSVTQVDALAELLGVANEP
MUL_1474|M.ulcerans_Agy99 VARPQLQPEPGEPADACADATAPKLLADTAQFSVTQVDALAELLGVGNEP
Mflv_3016|M.gilvum_PYR-GCK VPAADG--------------------------------------------
Mvan_3491|M.vanbaalenii_PYR-1 VPAAG---------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 T-------------------------------------------------
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M TPQFGPFARSYLAGLIAGLRSETGRRMAGVPTLPVSSPFDTGTRLWLDGL
MUL_1474|M.ulcerans_Agy99 TPQFGPSARSYLAGLIAGLRSETGRRMAGVSTLPISSPFDTGTRLWLDGL
Mflv_3016|M.gilvum_PYR-GCK APDLTDDEKLYIAGFLAGVDEGR----PGVPVLPAGAPVGARARLWVDGL
Mvan_3491|M.vanbaalenii_PYR-1 APEFTETEKLYLAGFFAGIEEGL----PGVPVLPASAPVGPRARLWVDGL
MAB_2438|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 ----------------------------------------RLDMAPTHTA
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------VRRIGAGMAATP
MMAR_3639|M.marinum_M LAGMFARAETPPALPFPQTPGAAAQSDNAAEAAVEQPPIVVLWASQTGTA
MUL_1474|M.ulcerans_Agy99 LAGMFARAETPPALPFPQTPGAAAQSDNAAEAAVEQPPIVVLWASQTGTA
Mflv_3016|M.gilvum_PYR-GCK LAGRYSRLETA------------------APSASPRGGPLVLWASQTGTA
Mvan_3491|M.vanbaalenii_PYR-1 LAGRYSRSDTV------------------AETPATEG-PLVLWASQTGNA
MAB_2438|M.abscessus_ATCC_1997 --GRTKADSMP------------------EKQKEALGDVAILWTSQTGNA
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu ----------------------------------------IDPLSQTSTL
MAV_4535|M.avium_104 APVSEAVAAGSPS-------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 EPVAHAVADEHL--------------------------------------
MMAR_3639|M.marinum_M EELAASVAAQLSAAELPVVLHGMDEFAVADLVSTQRLLLVTSTTGDGEPP
MUL_1474|M.ulcerans_Agy99 EELAASVAAQLSAAELPVVLHGMDEFAVADLVSTQRLLLVTSTTGDGEPP
Mflv_3016|M.gilvum_PYR-GCK EEFAGSLGERLA----GARLRAMDDTDLSELSDAGEVVIVTSTFGDGGPP
Mvan_3491|M.vanbaalenii_PYR-1 EEFAGRLGERLN----GARLRAMDDVELDDLSEAGEVVIVTSTFGDGGPP
MAB_2438|M.abscessus_ATCC_1997 ETAAVSVHRLLHTAGISATITAMDECDPADLVGVNTAVVIASSFGEGGPP
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu GTANVAIERSGA--------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M DNGAAFWRELCAATAPSLAGTRYSVLALGDSNYADFCGHGRALDHRLAEL
MUL_1474|M.ulcerans_Agy99 DNGAAFWRELCAPTAPSLAGTRYSVLALGDSNYADFCGHGRALDHRLAEL
Mflv_3016|M.gilvum_PYR-GCK DNGTAFWERLESADAPALDGVRYTVLGIGDRSYDNFCGHAKSLDTRLADL
Mvan_3491|M.vanbaalenii_PYR-1 DNGAGFWERLESPHAPSLDGVRYTVLGIGDRSYDNFCGHARSLDARLADL
MAB_2438|M.abscessus_ATCC_1997 DNGARFWAALSGDTKP-LNHMRYAVLGFGDRAYADFCGHAKALDARLHEL
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M GASRVTDRVDCEPDYEESAARWLQEVLDGLRRTAPPVITAAPVR--AASI
MUL_1474|M.ulcerans_Agy99 GASRITDRVDCEPDYEESAARWLQEVLDGLRRTAPPVITAEPVR--AASI
Mflv_3016|M.gilvum_PYR-GCK GATRMLDRADCEAYDEQPMAAWADSVVGLMSTPVTPAPT-------QPAV
Mvan_3491|M.vanbaalenii_PYR-1 GATRMLDRVECEAYDAQPLARWADSVVELVAAPGTPP----------AAP
MAB_2438|M.abscessus_ATCC_1997 GASPLLGRVDGEATDRTLVASWTADLLDAIGDGATAIVETVRKLRSEGLR
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M ANRPQGYTKKRPLLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGD
MUL_1474|M.ulcerans_Agy99 ASRPQGYTKKRPLLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGD
Mflv_3016|M.gilvum_PYR-GCK PAAPAPFTRGNPAQAPLCRNVRLTPDGAGKDVRQFGFDISGQDLAYSVGD
Mvan_3491|M.vanbaalenii_PYR-1 AQEPTLFTRAEPVAAPLCRNTRLTPQGAAKEVRQIGFDISAHDVTYSVGD
MAB_2438|M.abscessus_ATCC_1997 VAAPERFTRDAPILAALSHNELLSAPNSGKEVRRIEFDLTGHDVSYSAGD
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M ALGVWPRNAHQLVDEWLGVTQLDGHTEVEVAGHGTMSLRAALTDRFEIAH
MUL_1474|M.ulcerans_Agy99 ALGVWPRNAHQLVDEWLGVTRLDGHTEVEVAGHGTMSLRAALTDRFEIAH
Mflv_3016|M.gilvum_PYR-GCK SLGVWVVNSDAVVESWLSATGFHGAEAVIVDGR-QISLREALTRHYDVCK
Mvan_3491|M.vanbaalenii_PYR-1 SLGVCVVNSDFVVENWLAATDLRGDEAVVVDGV-QQALRDALTAHYDVCK
MAB_2438|M.abscessus_ATCC_1997 ALGIYPTNREEDVQRWLTTTGFDAQLPVTIDGG-ELPLATALANHYDICR
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M LSPDLLRFVAQRTLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQS
MUL_1474|M.ulcerans_Agy99 LSPDLLRFVAQRTLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQS
Mflv_3016|M.gilvum_PYR-GCK VTSNLVTFVAEHCPDAATA----KRLRN-DRGALDTWLVDRNGLDLVREF
Mvan_3491|M.vanbaalenii_PYR-1 VTSNLVKFVAEHCRDAATA----KRLRN-DRGELDRWLVNRNGLDLVREF
MAB_2438|M.abscessus_ATCC_1997 VTEDLLRFIAERRRDKHSA----KLLQGRDTQAREVWLRGRNALDVIREF
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M PVRASVDEWMSVLKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVP
MUL_1474|M.ulcerans_Agy99 PVRASVDEWMSVLKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVP
Mflv_3016|M.gilvum_PYR-GCK GIRADPALWQEVLVRLTPRQYSISSSPLVSPHEVQLTVSVVRYRGADGTP
Mvan_3491|M.vanbaalenii_PYR-1 SVRADPQLWQEVLVRLTPRQYSISSSPLVSPNEVQLTVSVVRYRGADGGP
MAB_2438|M.abscessus_ATCC_1997 PIRAAIEEWQQVLIRLTPRQYSISSSPLVSPQAISLTVSIVRYQGPDGSP
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M RRGVCSTYLADRSPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPF
MUL_1474|M.ulcerans_Agy99 RRGVCSTYLADRSPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPF
Mflv_3016|M.gilvum_PYR-GCK RGGVASTYLADLPDCTPVPVFLQRSPHFRPPEDPHTPMIMVGPGTGIAPF
Mvan_3491|M.vanbaalenii_PYR-1 RGGVASTYLADLPDGTAVPVFLQRSPHFRPPQDSHTPMIMVGPGTGIAPF
MAB_2438|M.abscessus_ATCC_1997 RGGVGSTFLADRAQHLPVPIFLQRSPHFRPPRTSDTPMIMIGPGTGIAPF
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M RGFLQERRALGHTGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLA
MUL_1474|M.ulcerans_Agy99 RGFLQERRALGHTGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLA
Mflv_3016|M.gilvum_PYR-GCK RGFLQERRALGHRGANWLFFGDQHREQNFYYRDDLLDMVDDGFLNRLDLA
Mvan_3491|M.vanbaalenii_PYR-1 RGFLQERRALGHRGPNWLFFGDQHRAQNFYYRDDLQDMVDDGFLNRLDLA
MAB_2438|M.abscessus_ATCC_1997 RGFLQERRALGHTGANWLFFGDQHRTEHFYYRDELDGFLRDGSLRRLDLA
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M FSRDQRDKVYVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLC
MUL_1474|M.ulcerans_Agy99 FSRDQRDKVYVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLC
Mflv_3016|M.gilvum_PYR-GCK FSRDQRQRIYVQHKMLDYGADVWRWLDDGAHFYVCGDATRMAKDVDDALT
Mvan_3491|M.vanbaalenii_PYR-1 FSRDQARRVYVQHKMLDYGADVWRWLDDGAHFYVCGDATRMAGDVDDALT
MAB_2438|M.abscessus_ATCC_1997 FSRDQAKRIYVQHRMMEQGAQLWRWLNEGAHLYVCGDASRMAKDVDGALL
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
TH_4483|M.thermoresistible__bu --------------------------------------------------
MAV_4535|M.avium_104 --------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------
MMAR_3639|M.marinum_M QIVAEHGGLDPESATAFVHALSADKRYHRDVY
MUL_1474|M.ulcerans_Agy99 QIVAEHGGLDPESATAFVHALSADKRYHRDVY
Mflv_3016|M.gilvum_PYR-GCK EILRTHARMSSDAAREYKREMVAEKRYVRDVY
Mvan_3491|M.vanbaalenii_PYR-1 EIIRTHGGMSADAARDYKREMVAEKRYVRDVY
MAB_2438|M.abscessus_ATCC_1997 TIAQKHGKLSGEQALEFRKELVAEKRYVRDVY
Mb2924c|M.bovis_AF2122/97 --------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------
TH_4483|M.thermoresistible__bu --------------------------------