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ARGTGRKDRAPGTFGSVDKLATGYRARYFGPDGRRHKAPVLFLTKTDARAWLAQRHSEIVAQQWTPPNAV EVPKTTFTEYADQWLLTRQVAGRPLKDRTREHYQALLDDHITATFGALPLASITADDVRQWYARTLTDKP TMRSHAYGLLRTILATAVSDGKISVNPCSIRGAGTAKRVHKVRPATVGEIGTIADAMPAQWSLMVLLAAW LAMRFGELTELRRKDIDLADEVVRVRRAVVRTDDGFKVTTPKSDAGIRDIAIPPHLIPPIEAHLSQHVGA KADALLFPAVGGGHLAPATLYRRFYTARERANRKDLRWHDLRHSGAVLAAATGATLAELMARLGHSTPQA ALRYQHAAQGRDRQIAALLSKIAENGGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3899 | - | - | 100% (379) | phage integrase family protein |
| M. gilvum PYR-GCK | Mflv_2927 | - | 2e-25 | 26.99% (389) | phage integrase family protein |
| M. gilvum PYR-GCK | Mflv_2786 | - | 1e-05 | 28.40% (169) | phage integrase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2335c | - | 6e-08 | 29.27% (123) | hypothetical protein Mb2335c |
| M. tuberculosis H37Rv | Rv2659c | - | 1e-120 | 60.64% (376) | phiRv2 prophage integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4848 | - | 1e-22 | 29.26% (311) | prophage integrase |
| M. avium 104 | MAV_1484 | - | 2e-55 | 37.07% (348) | integrase |
| M. smegmatis MC2 155 | MSMEG_5754 | - | 1e-09 | 23.83% (386) | gp41 protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0529 | - | 8e-22 | 28.94% (311) | prophage integrase |
| M. vanbaalenii PYR-1 | Mvan_2508 | - | 1e-138 | 65.37% (387) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4848|M.marinum_M -MAGSVPRGIRKRTNSAGQARYQVRYLVRDPNSPSGWVETSSTFATMREA
MUL_0529|M.ulcerans_Agy99 -MAGNTPRGIRKRLNAAGEPRYQVRYLIRDPDAPSGWVETSATFPTLREA
Mflv_3899|M.gilvum_PYR-GCK MARGTGRKDRAPGTFGSVDKLATG-YRARYFGPDGRRHKAPVLFLTKTDA
Mvan_2508|M.vanbaalenii_PYR-1 MARGEGRKTRQAGTFGTVQQLPSGRYRAMYYGPDRRRYKAPTTFRAKADA
Rv2659c|M.tuberculosis_H37Rv -MTQTGKRQRRK--FGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDA
MAV_1484|M.avium_104 -----------------MRQLPSGRWQASYLH-NGVVFKALATFPTKSSA
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_5754|M.smegmatis_MC2_155 -MLQRMARIPDYVKVIDLDSGRRYEVRPEVTGADGKRRQKRERFKTLKEA
MMAR_4848|M.marinum_M RAFKADRDGEAAIG--------------ARRFDPRLGRASLSAIWTQYSA
MUL_0529|M.ulcerans_Agy99 KAFKSERDNEAALG--------------ARRFDPRLGRTPLSRIWTQFSD
Mflv_3899|M.gilvum_PYR-GCK RAWLAQRHSEIVAQ-----QWTPP---NAV-EVPKTTFTEYADQWLLTRQ
Mvan_2508|M.vanbaalenii_PYR-1 RGWLALRQAEIISK-----AWTPP---EAAPKITRTTFADYARNWIKQ--
Rv2659c|M.tuberculosis_H37Rv EAWLTDRRREIDRQ-----LWSPA---SGQEDRPGAPFGEYAEGWLKQ--
MAV_1484|M.avium_104 GHWLQAEEDLIDLDRRRPGEWTPPAERAARRQAEKLTLRTYAKTWLDN--
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_5754|M.smegmatis_MC2_155 VDHYTAIAGDRGRG--------------VHVAPSELTVEDAVDSWLLG--
MMAR_4848|M.marinum_M SKQPAVSPKTWSGYAQHWELRISPRFGHVPVDEISRKDVQQFIGGLTVG-
MUL_0529|M.ulcerans_Agy99 SKKPAVSPKTWSGYNQHWELRIKPRFGHVPVDEITRADVRAFVDGLTVG-
Mflv_3899|M.gilvum_PYR-GCK VAGRPLKDRTREHYQALLDDHITATFGALPLASITADDVRQWYARTLTDK
Mvan_2508|M.vanbaalenii_PYR-1 ---RDLKQHTREHYEVLLERHLISPFGSLPLSSITVDDVRGWYATFATET
Rv2659c|M.tuberculosis_H37Rv ---RGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVGT
MAV_1484|M.avium_104 --KTKLARRTRDNYQGHLDNHVLPALGDLGLADITPEHVRTWFAGLGNEH
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_5754|M.smegmatis_MC2_155 ---QRIRPKTMSAYITSLR-PIVDHLGKRTVQSITKDDLEQVVQALRAGT
MMAR_4848|M.marinum_M PWAKLA------------------------TLRLLRSILDMAREDGRIHI
MUL_0529|M.ulcerans_Agy99 PWAKVS------------------------TLRLLRSILDVAHQDGRIHR
Mflv_3899|M.gilvum_PYR-GCK PTMRSH------------------------AYGLLRTILATAVSDGKISV
Mvan_2508|M.vanbaalenii_PYR-1 PTLRSH------------------------TYGLLRTILGTAASDGKISS
Rv2659c|M.tuberculosis_H37Rv PTMRAH------------------------SYSLLRAIMQTALADDLIDS
MAV_1484|M.avium_104 ETRNAQ------------------------AYAVLNGVFNTAVADDLIDR
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_5754|M.smegmatis_MC2_155 SKMGTWNAPTKLTKAAKKVRSPWAASSINPMLARTRSIFEDLVNQGVVVR
MMAR_4848|M.marinum_M NPAQGVSSGRIPARER-HRYLSATEVAALAHACGDQGDIVTILA-FTGLR
MUL_0529|M.ulcerans_Agy99 NPALGVSAGRIPERER-HRYLTAQEVRMLATACGDQGDVVTILA-YTGLR
Mflv_3899|M.gilvum_PYR-GCK NPCSIRGAGTAKRVHK-VRPATVGEIGTIADAMPAQWSLMVLLAAWLAMR
Mvan_2508|M.vanbaalenii_PYR-1 NPCLIRGAGTTKRVKK-IRPATLPEIEKITTEMPEQYQAMILLAAWCALR
Rv2659c|M.tuberculosis_H37Rv NPCRISGASTARRVHK-IRPATLDELETITKAMPDPYQAFVLMAAWLAMR
MAV_1484|M.avium_104 NPCRIRGAAQVKHARRSVVLLDATQLTALAEKMPDDARLGVLLAGWCGLR
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_5754|M.smegmatis_MC2_155 NVAALVKP-LATDTEKTMNTLNAEQVTQLLAVTDSHCYGIAWRLAVLGLR
MMAR_4848|M.marinum_M WSELVGLRVGDIDLKA-----------RRLYVRQAAPDVEGRIIVGPPKT
MUL_0529|M.ulcerans_Agy99 WSEPVGLRVKDIDLTA-----------RRLYVRRAAPEVEGHIVIGPPKT
Mflv_3899|M.gilvum_PYR-GCK FGELTELRRKDIDLAD-----------EVVRVRRAVVRTDDGFKVTTPKS
Mvan_2508|M.vanbaalenii_PYR-1 FGELTELRRKDIVLTTTVDLEGETVHMGVIRVERAVVRVDDGYLVTTPKS
Rv2659c|M.tuberculosis_H37Rv YGELTELRRKDIDLHG-----------EVARVRRAVVRVGEGFKVTTPKS
MAV_1484|M.avium_104 KGEVFALRRGDVAADG-----------SSVRIERSVTYREGRFEVGPTKT
Mb2335c|M.bovis_AF2122/97 --------------------------------------MTGAGIVETTTN
MSMEG_5754|M.smegmatis_MC2_155 RGEILALRWDAVDFDAG-----------TLAISAARLATAGGATTGAPKT
....
MMAR_4848|M.marinum_M RAAVRTVPLPRIVIDALKPRIENRSTKE-------QAITSPNGGFLRSNN
MUL_0529|M.ulcerans_Agy99 RAGIRTVPLPQVVVDIFKGRITGQAPDQ-------PAVTSTNGAMLRSNN
Mflv_3899|M.gilvum_PYR-GCK DAGIRDIAIPPHLIPPIEAHLSQHVGAKADA-LLFPAVGG--GHLAPATL
Mvan_2508|M.vanbaalenii_PYR-1 DAGTRDVAIPPHLVPVIHDHLAVHVDGGPDA-LLFPAAHG--RHLAPATL
Rv2659c|M.tuberculosis_H37Rv DAGVRDISIPPHLIPAIEDHLHKHVNPGRES-LLFPSVNDPNRHLAPSAL
MAV_1484|M.avium_104 RESRRVVSVPPHVRPAVLEHLQRHVADGDDA-LVFVEPST--GSFAGEKR
Mb2335c|M.bovis_AF2122/97 R--VRHVPVP----EPVSERLRDELPTEPNA-LVFPSYRG---GHLPIEE
MSMEG_5754|M.smegmatis_MC2_155 KTSVRTLPMPEDLTAALRRVRKRQKEYRLKLGSKWTDSGYVVVDEFGVAP
* :.:* . .
MMAR_4848|M.marinum_M WRR--HTHWNKALKKTGLAPLTIHDLRHTYASLARKSGADLRYVQKTMGH
MUL_0529|M.ulcerans_Agy99 WRR--HTHWNKALKSTDLAPLTIHDLRHTYASLARKSGADLRYVQKTMGH
Mflv_3899|M.gilvum_PYR-GCK YR----RFYT-ARERANRKDLRWHDLRHSGAVLAAATGATLAELMARLGH
Mvan_2508|M.vanbaalenii_PYR-1 YR----QFYK-ARVAADRPDLRFHDLRHSGAVLAAATGATLAELMARLGH
Rv2659c|M.tuberculosis_H37Rv YR----MFYK-ARKAAGRPDLRVHDLRHSGAVLAASTGATLAELMQRLGH
MAV_1484|M.avium_104 FR----TAWESARAAIGQPDMHFHDLRHAAGVMAAQTGATVRELMDRLGH
Mb2335c|M.bovis_AF2122/97 YR----RAFDKGCKAVGIADLVPHGLRHTTASLAISAGANVKVVQRLLGH
MSMEG_5754|M.smegmatis_MC2_155 YPDTLTAAWRKTLANAGLPHVRLHDARHSCATLMHLSGVPTVVIAAWLGH
: : . : *. **: . : :*. : :**
MMAR_4848|M.marinum_M STPTVTANIYSDLYSDELDHVATNLDRLNDVAKDQAN-GQEPDTPKHP--
MUL_0529|M.ulcerans_Agy99 STPTVTANIYSDLYADELDQVATNLDQLHATEIQTPTTGQEPDEPNQPSS
Mflv_3899|M.gilvum_PYR-GCK STPQAALR-YQHAAQGRDRQIAALLSKIAENGGA----------------
Mvan_2508|M.vanbaalenii_PYR-1 STPQAAMR-YQHAAQGRDQAIAAALSKIALGQ------------------
Rv2659c|M.tuberculosis_H37Rv STAGAALR-YQHAAKGRDREIAALLSKLAENQEM----------------
MAV_1484|M.avium_104 TSPNMSMR-YQHTAEGRAAALADKLSALASTNP-----------------
Mb2335c|M.bovis_AF2122/97 ATAAMTLDRHGHLLSDDLAGVAGLLVQAIKSAAASLRYSDPDSVAVENIS
MSMEG_5754|M.smegmatis_MC2_155 QDPGFTLRTYAHSNHDALADAAAMLGSITTGKKKEAK-------------
. : : . . * *
MMAR_4848|M.marinum_M ---
MUL_0529|M.ulcerans_Agy99 A--
Mflv_3899|M.gilvum_PYR-GCK ---
Mvan_2508|M.vanbaalenii_PYR-1 ---
Rv2659c|M.tuberculosis_H37Rv ---
MAV_1484|M.avium_104 ---
Mb2335c|M.bovis_AF2122/97 AAS
MSMEG_5754|M.smegmatis_MC2_155 ---