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TAGRVLKALIPLILIAFGVLWPVVFDGGSGDPTDIDDPVVISHYDVNMAIAADGTMTAVETITTEFYSTD RHGIFRYWDVANQNDPHLRQKPEIQSILLDGRPVTYQMLWEDAGRFRVAKIGDADRYLSDGTHVFEIRYT IPGVLDPGDVGADRQFAETVGGGTPSESVFFWNVIAPAWNNRIERADVTLTLPGGAGAAQCSVGFGVGRG CDGLTVDGNRVRFSAQDLPPRTPVTVRAGVDVPTPPRATLPWPYTWDRVLGQSVSGAVGVGALAVLLGAV ALLWFRSVLEKPPGFPLQYAPPPGLGPVQAEYIRTESVSKHGLTATLFYLAEQDLIRLRQVNDTHWKITS TAEPGRWGDVDPVSVAVASRLKIINRGSEFEAKKTAKSGEKLNKAKTDMAKAVESWALDSGLMVPRRKEL WLRAANAVAFILMVCAFFRWGFPATMWAVPFAVFFLLSAGSWRDGVGTRRTAAGRDLWSRVGGFHRLLST DSAESRFDFSARKDLYIAYVPFAVAAGVAAVWAQKYQDYTGSVAPQPEWYGSSHSSSSGTAFSGGAGGGD FDSFESALSSSIGAYTASQASSSSSGGGSSSSSGGGGGGGGGGGGGSW*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3732 | - | - | 100% (609) | hypothetical protein Mflv_3732 |
M. gilvum PYR-GCK | Mflv_5091 | - | 2e-05 | 36.07% (61) | triple helix repeat-containing collagen |
M. gilvum PYR-GCK | Mflv_2720 | - | 7e-05 | 29.93% (147) | hypothetical protein Mflv_2720 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 2e-06 | 40.00% (60) | PE-PGRS family protein |
M. tuberculosis H37Rv | Rv3345c | PE_PGRS50 | 7e-07 | 35.38% (65) | PE-PGRS family protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1280c | - | 8e-05 | 32.50% (80) | hypothetical protein MAB_1280c |
M. marinum M | MMAR_0884 | - | 3e-08 | 44.87% (78) | hypothetical protein MMAR_0884 |
M. avium 104 | MAV_0118 | - | 2e-05 | 32.00% (100) | PPE family protein |
M. smegmatis MC2 155 | MSMEG_3062 | - | 0.0 | 63.86% (606) | hypothetical protein MSMEG_3062 |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_2783 | - | 4e-07 | 42.42% (66) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_2685 | - | 0.0 | 78.33% (609) | hypothetical protein Mvan_2685 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3541|M.bovis_AF2122/97 ------------MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQ Rv3345c|M.tuberculosis_H37Rv -----------MVMSLMVAPELVAAAAADLTGIGQAISAANAAAAGPTTQ MUL_2783|M.ulcerans_Agy99 ------------MPHVTTSPNLLAATAGDLAAIASTMRQASAAAAAPTAA Mflv_3732|M.gilvum_PYR-GCK ------------MTAGRVLKALIPLILIAFGVLWPVVFDGGSGDPTDIDD Mvan_2685|M.vanbaalenii_PYR-1 ------------MSVGRLVKALIPLILIAFGVLWPVVFHGGS-SASEIDD MSMEG_3062|M.smegmatis_MC2_155 --------------MRRVVAWTFTLALIVFGLLWPVIFAGGGGDAANVDD MAB_1280c|M.abscessus_ATCC_199 -----------MGKKQIQKEHWEGHDHQSIYNAAQAFQTGNPQAAQESIN MAV_0118|M.avium_104 MTAPVWMALPPEVHSTLLSSGPGPGPLLAAAATWTGLSTQYDSAATELTA MMAR_0884|M.marinum_M ---------MDVVLGVAIAGPIARLALVGAAAEGSAVIDQSSVDLAEGPV . Mb3541|M.bovis_AF2122/97 VLAAGADEVSARIAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYM Rv3345c|M.tuberculosis_H37Rv VLAAAGDEVSAAIAALFGTHAQEYQALSARVATFHEQFVRSLTAAGSAYA MUL_2783|M.ulcerans_Agy99 VQPAGGDVVSAGIASLFGAHAYNYQVLSAKAAEFHDRFVEILQTSAQAYG Mflv_3732|M.gilvum_PYR-GCK PVVISHYDVNMAIAADGTMTAVETITTEFYSTDRHGIFRYWDVANQNDPH Mvan_2685|M.vanbaalenii_PYR-1 PVVIADYDVDMVVDDAGDMTAVETLTTEFYTTARHGIFRYWDVANPNSPY MSMEG_3062|M.smegmatis_MC2_155 PVVITDYRAQFSIDADGEMKAVETITAEFPS-GRHGIFRYWDVANPNNPH MAB_1280c|M.abscessus_ATCC_199 SIAEQLGDIMHTLGGKVQGILVEDWRGAAAKSLQANMSEYFRASERGIIS MAV_0118|M.avium_104 VLTGSMPVWDGPTADRYVAAHMPYLAWLQLAGALSAEAAAQHQGVATAYT MMAR_0884|M.marinum_M AVLTETIVGTNQLLADEGHHLVATRLCWSDQDRAEDLRRALDDSGVLDVA Mb3541|M.bovis_AF2122/97 LAEATN------VEQNLLNLINAPTQTLLGRPLIGDGAN-ATTPGGAGGD Rv3345c|M.tuberculosis_H37Rv TAEAANASPLQALEQQVLGAINAPTQLWLGRPLIGDGVHGAPGTGQPGGA MUL_2783|M.ulcerans_Agy99 STEATN-------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK LRQKPE--------------------------------------IQSILL Mvan_2685|M.vanbaalenii_PYR-1 VRQKPE--------------------------------------VTSVLL MSMEG_3062|M.smegmatis_MC2_155 VRQIPE--------------------------------------ITSIDL MAB_1280c|M.abscessus_ATCC_199 IRHVADR---------------------------------MPPLADAMSA MAV_0118|M.avium_104 AALAAMP--------------------------------TLPELAANHAT MMAR_0884|M.marinum_M VLSESE------------------------------------AVTALLGP . Mb3541|M.bovis_AF2122/97 GGLLFGSGGNGAPGAPGQAGGAGGSAGLLGNGGSGGAGGTGAPGGNGGNA Rv3345c|M.tuberculosis_H37Rv GGLLWGNGGNGGSGAAGQVGGPGGAAGLFGNGGSGGSGGAGAAGGVGGSG MUL_2783|M.ulcerans_Agy99 ASPLEKAIGVFTAPAEGQAGGPGTGNGAIGGGLHGGAGGFGDVGQPTAN- Mflv_3732|M.gilvum_PYR-GCK DGRPVTYQMLWEDAGRFRVAKIGDADRYLSDGTHVFEIRYTIPGVLDPG- Mvan_2685|M.vanbaalenii_PYR-1 DGRPVPYQMLWEDVGRFRVAKIGDPDRYLSDGTHVFEIRYTIPGVLDPG- MSMEG_3062|M.smegmatis_MC2_155 DGRPAPYEMQWADNQRFRIAKIGDPDSTLSYGTHVFEIAYTVPGVLDPG- MAB_1280c|M.abscessus_ATCC_199 AKRSIEPPMSDAQISQLKKSGSSDADIQQRKNQEQFFARLQMVGLFSEP- MAV_0118|M.avium_104 HAALVATNFFGVNTIPIAVNEADYARMWTQAATTMTTYQATTEAVQMTS- MMAR_0884|M.marinum_M AHAGSAVLLVGEETASLSVLGGGDAPPTMLAAAPVEGDATSTFDTLMAHL . Mb3541|M.bovis_AF2122/97 GWLYGRGGVGGAGGIGGGTGGAGGHAWLFGHGGTGGIGGGPGGNGGWLLG Rv3345c|M.tuberculosis_H37Rv GWLNGNGGAGGAGGTG-ANGGAGGNAWLFGAGGSGGAG-----------T MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M D------------------------------------------------- Mb3541|M.bovis_AF2122/97 NGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGGAGGTGGGAGGTGGNAAWL Rv3345c|M.tuberculosis_H37Rv NGGVGGSGGFVYGNGGAGGIG-------GIGGIGGNGGDAG--------L MUL_2783|M.ulcerans_Agy99 ------------------------------------AAPVG--------- Mflv_3732|M.gilvum_PYR-GCK --------------------------------------DVG--------- Mvan_2685|M.vanbaalenii_PYR-1 --------------------------------------GTG--------- MSMEG_3062|M.smegmatis_MC2_155 --------------------------------------SVG--------- MAB_1280c|M.abscessus_ATCC_199 ------------------------------------VVREG--------- MAV_0118|M.avium_104 --------------------------------------VAG--------- MMAR_0884|M.marinum_M -----------------------------------DQG------------ Mb3541|M.bovis_AF2122/97 LGGGGTGGAGGIGGGNGGHGGNGGWLLGNGGNGGLGGDGDGGTGGGHGGN Rv3345c|M.tuberculosis_H37Rv FGNGGAGGAGAAG------------------------------------- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGTGGDGGTGGRGGLLMGAGA Rv3345c|M.tuberculosis_H37Rv ------LPGAAG--LNGGDGSD-------GGNGGTGGNGGRGGLLVGN-- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGHGGTGGAGGAGVDGGGAGGAGGAGGNGGAGGQAALLFGRGGTGGAGGY Rv3345c|M.tuberculosis_H37Rv ----------------GGAGGAGGVGGDGGKG------------------ MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGDGGGGGDGFDGTMAGLGGTGGSGGTGGDGGAPGNGGAGGAGQLLSHSG Rv3345c|M.tuberculosis_H37Rv -----GAGD------PSFAVNNGAGGNGGHGGNPGVGGAGGAGGLLAG-- MUL_2783|M.ulcerans_Agy99 --------------------PAGATAAAGTGGSP---------------- Mflv_3732|M.gilvum_PYR-GCK ------------------ADRQFAETVGGGTPSESVFFWNVIAPAWNN-- Mvan_2685|M.vanbaalenii_PYR-1 ------------------ADRQFAGSTGGPDSSPSVFYWNVIAPAWNN-- MSMEG_3062|M.smegmatis_MC2_155 ------------------ADRRFAAESGDPQ-APTTFYWNVIAPAWNN-- MAB_1280c|M.abscessus_ATCC_199 --------------------DNVTDVRPPQGNNPG--------------- MAV_0118|M.avium_104 ---------------------SGTGGKAGSGSGSGTG------------- MMAR_0884|M.marinum_M -------------------GAPGEVLLVGSSEHTTVIADQFRDASTMR-- Mb3541|M.bovis_AF2122/97 VAGASGKGGAGGTGGNGGAGSAGADAPAGSGAMGSTGFAGGAGGDGGNGG Rv3345c|M.tuberculosis_H37Rv ----------------------------AHGAAGATPTSGGNGGDGGIGA MUL_2783|M.ulcerans_Agy99 --------------------------------AQATVHSGPAAGNGD-AA Mflv_3732|M.gilvum_PYR-GCK ----------------------------RIERADVTLTLPGGAGAAQCSV Mvan_2685|M.vanbaalenii_PYR-1 ----------------------------RIDRADITVTLPGDIGTAQCSV MSMEG_3062|M.smegmatis_MC2_155 ----------------------------FIRHADITVALPADATGAQCSV MAB_1280c|M.abscessus_ATCC_199 ---------------------------------NITLQQPANGSESGTGG MAV_0118|M.avium_104 -------------------------------AGTGTGTGTGTGTGTGTGT MMAR_0884|M.marinum_M ----------------------------VEVPEDPTFALARGAAMAAAGA * . Mb3541|M.bovis_AF2122/97 GSGASQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGG Rv3345c|M.tuberculosis_H37Rv TANSPLQAGGAGGNGGHGGLVGNGGT-------------GGAGGAG-HAG MUL_2783|M.ulcerans_Agy99 SVGTGVQHGGAGGGSGDGMASSHVSD-------------GGAARAGGAAN Mflv_3732|M.gilvum_PYR-GCK GFGVGRGCDGLTVDGNRVRFSAQDLPPR-----------TPVTVRAGVDV Mvan_2685|M.vanbaalenii_PYR-1 GFGVGRECDELTVDGNRVQLTAESLPPR-----------TPVTLRVGVDV MSMEG_3062|M.smegmatis_MC2_155 GYGVGTPCD-LTVSGNTVRLQADNLEPR-----------TPVTLRAGVDV MAB_1280c|M.abscessus_ATCC_199 GGGGGQNGGGSGGGQGSGDLSKLTDG--------------LADKNTKPAF MAV_0118|M.avium_104 GTGAGSGTGGGTGAGGGGGTGSFQLPTPEEIWEMLFGPDGEQIPGQGQPN MMAR_0884|M.marinum_M GSTMAQQVLGGDAGEATTYLPPELAATAS-----------GQDEDEQLAY Mb3541|M.bovis_AF2122/97 NAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGA Rv3345c|M.tuberculosis_H37Rv STGATGTALQP-TGGNGTNGGAGGHGGNGGNGGAQHGDGGVGGKGGAGGS MUL_2783|M.ulcerans_Agy99 SAGG--------TDAAASSSGAGGGGSAG---------------QGVAST Mflv_3732|M.gilvum_PYR-GCK PTPPRATLPWPYTWDRVLGQSVSGAVGVGALAVLLGAVALLWFRSVLEKP Mvan_2685|M.vanbaalenii_PYR-1 PTPPRAEVLWPHTWDRVLGRSVDGVAWMVGLTVAFGILALLWFRSVLERS MSMEG_3062|M.smegmatis_MC2_155 PTPAQAELPWPYTWDPVLGRSVPRVVTTGVLTVLAALGALMWLRTTIEPS MAB_1280c|M.abscessus_ATCC_199 SDGS----------GNQSGQGQGAGAGSG---------------SGAGGG MAV_0118|M.avium_104 WSPSEYLQNLGNFFNGNAQAVAWLQQNLSGLLNPSQFPALINYFIAWQTY MMAR_0884|M.marinum_M SQAGENELLPVTGADEYGDYGPDDDEFADDYEDEAPAGTRLSSRSLLISN Mb3541|M.bovis_AF2122/97 GGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLL Rv3345c|M.tuberculosis_H37Rv GGAGGNGFDAATLGS-PGADGGMGGNGGKGGDGGKAGDGGAGA------- MUL_2783|M.ulcerans_Agy99 GGDHGAGATSSASGHSPGHGVGLGSGLGRSLDG----------------- Mflv_3732|M.gilvum_PYR-GCK PGFPLQYAPPPGLGPVQAEYIRTESVSKHGLTATLFYLAEQDL------- Mvan_2685|M.vanbaalenii_PYR-1 PGFPLQYAPPPGLGPVQAEYIRTESVSKHGLTATLFYLAERDL------- MSMEG_3062|M.smegmatis_MC2_155 PGFPVQYAPPDGLGPVQLEFIRTEAVPSNGLTATLFHLADRGL------- MAB_1280c|M.abscessus_ATCC_199 SPQSGSGGSGSGLGNALSGLGGSSDKTG---------------------- MAV_0118|M.avium_104 RIINWTIRTLRFILQELPLLLQVGLSLSITSLGGLAGLAGLAG------- MMAR_0884|M.marinum_M AVVAFAVIGFASLAVAVAVAIRPTASSEPVEGHQNAQPGKFMP------- Mb3541|M.bovis_AF2122/97 AAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADN Rv3345c|M.tuberculosis_H37Rv ----------------AGDVTLAVNQGAGGDGGNGGEVGVGGKGGAGGVS MUL_2783|M.ulcerans_Agy99 ------------------YGTAALAGGPLGAVGSGAPGAVGGVGELLAPT Mflv_3732|M.gilvum_PYR-GCK ------------------IRLRQVNDTHWKITSTAEPGRWGDVDPVSVAV Mvan_2685|M.vanbaalenii_PYR-1 ------------------VALRQVSDEHWEIKGIAEPGKWADVDPVSIAV MSMEG_3062|M.smegmatis_MC2_155 ------------------ISLRQESETRWSIRGMAAPAAWADADEVGIAV MAB_1280c|M.abscessus_ATCC_199 ---------------------SGLPLGSTTAAGYSSPSSSGS--GAGTLS MAV_0118|M.avium_104 ------------------LAGLAAPASAPAPAAMPQPAGMGAQPPVVSAA MMAR_0884|M.marinum_M -----------------LLPTQQQAPVPPPPPDAPTAGFQGGTIPTVQGV . Mb3541|M.bovis_AF2122/97 TTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGK Rv3345c|M.tuberculosis_H37Rv ANPALNGSAGANGTAPTSGGNGGNGGAGATPTVAGE-NGGAGGNGGHGG- MUL_2783|M.ulcerans_Agy99 ATSALPTAASATAEPSLAMSTKAQLVRATNPLQPVNPAHSDS-------- Mflv_3732|M.gilvum_PYR-GCK ASRLKIINRGSEFEAKKTAKSGEKLNKAKTDMAKAVESWALDSG------ Mvan_2685|M.vanbaalenii_PYR-1 ASRLKVLNPGSEFDAKKTVKSGEKLNKAKADMAKAVEKWAVESG------ MSMEG_3062|M.smegmatis_MC2_155 GAALKVMSPGATFRADGSVTAGKKLNRAKTDMADAVKKWAFDGG------ MAB_1280c|M.abscessus_ATCC_199 GPGALRGGAGVPGLGGGAGTNPTGIGGAGVRGGAMGMGGMG--------- MAV_0118|M.avium_104 PAMAPMAPTSPVAPATSAVSTPAPVASAIAPPATPPVPPAPVTG------ MMAR_0884|M.marinum_M VPRQATPTVPAPVAPAPAPAPGVVPAPIPLPIPIIIPPWPNWSPG----- : Mb3541|M.bovis_AF2122/97 GGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNG Rv3345c|M.tuberculosis_H37Rv ------------------SVGNGGAGGAGGNGVAG-----TGLALNGGNG MUL_2783|M.ulcerans_Agy99 ------------------SANQGGPARRTGVERDGPTLFLPLTSLR---- Mflv_3732|M.gilvum_PYR-GCK -----------------LMVPRRKELWLRAANAVAFILMVCAFFRWG--- Mvan_2685|M.vanbaalenii_PYR-1 -----------------LLVPRKKELWLRAANVAAFVLMICGFFRWG--- MSMEG_3062|M.smegmatis_MC2_155 -----------------LMVRRRKELWLRVANLFAFIAALAGFCLWFG-- MAB_1280c|M.abscessus_ATCC_199 ------------------MAPMGGAHGRGGHGEEDDEHQTPEFLINWD-- MAV_0118|M.avium_104 ------------------AEGFGYMVGSFGLGMDSKAQTRARSALAAG-- MMAR_0884|M.marinum_M -----------------MPTPSTVTVTPTTPTTTAPSTVTPTTPTTTAP- Mb3541|M.bovis_AF2122/97 GDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQ Rv3345c|M.tuberculosis_H37Rv GNGGIGGNGGSAAG---------TGGDGGKGGNGGAGANGQDFSASANG- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 QGNGGNGGNGGTGGKGGTGGDGALAGSSGGAGGKGGNGGDAGKAGTGSAP Rv3345c|M.tuberculosis_H37Rv -ANGGQGGNGGNGGIGGKGGDAFATFAKAGNGGAGGNGGNVGVAGQ---- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GTAGTGGDGGKGGNGGIGAAGTTGPVGTGASGGTGGSGGAGGTGGDGGAA Rv3345c|M.tuberculosis_H37Rv --------GGAGGKGAIPAM-------------------KGATGADGTAP MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 NGGTAGAGGAGGNGGKGGDGGAGVTSSTAGNSGGAGGSGGKGGDAGAGGA Rv3345c|M.tuberculosis_H37Rv TS-----------GGDGGNGGNGASPTVAGGNGGDGGKGGSGGNVGNG-- MUL_2783|M.ulcerans_Agy99 -------------------GLRRHSKKRSGLRAQSGRLRDSGDAVSSP-- Mflv_3732|M.gilvum_PYR-GCK ------------------FPATMWAVPFAVFFLLSAGSWRDGVGTRRT-- Mvan_2685|M.vanbaalenii_PYR-1 ------------------FPATMWALPFAAFFLFSAGSWRDGVGTRRT-- MSMEG_3062|M.smegmatis_MC2_155 ------------------ISATMVGLPFAAFFAFSVGCWPAGLGTRRT-- MAB_1280c|M.abscessus_ATCC_199 ------------------NGNELFGDLPKASPGVIGDWSEHERAEKQR-- MAV_0118|M.avium_104 -------------------RPAASSAGAAAVEQEQGRTRRRPRSVIDPG- MMAR_0884|M.marinum_M ----------------STVTPTTPTTTAPSTLTPTTPTTTVPSTVITP-- Mb3541|M.bovis_AF2122/97 GATPGANGIAGNGGDGGDGAAGAVGISGATGAGDGGHGGTGGAGGNGGTG Rv3345c|M.tuberculosis_H37Rv ----------GNGGAGGNGAAGQAGTPGPTSGDSGTSGTDGGAGGNGGAG MUL_2783|M.ulcerans_Agy99 -------------RWEPDDLLRALGLRPPGHQ------------------ Mflv_3732|M.gilvum_PYR-GCK -------------AAGRDLWSRVGGFHRLLSTDSAESRFDFSARKDLYIA Mvan_2685|M.vanbaalenii_PYR-1 -------------AAGRELWSRAGGFHRMLATDSAETRFDFSARKDLYTA MSMEG_3062|M.smegmatis_MC2_155 -------------PAGRQLWSRAGGFHRLLSTDSAETRFDFAARKDLYVA MAB_1280c|M.abscessus_ATCC_199 -------------RESEKRRYKSMGWNVDFGDDD---------------- MAV_0118|M.avium_104 --------YRYEFIEGDDEVVAVASAAQDRYRPSDSGGSIQGFAGTLPKS MMAR_0884|M.marinum_M -------------TTTAPITPTTVAPTTVNPTTVAPTTVAPTTQQTVVPQ . Mb3541|M.bovis_AF2122/97 GAGGSGIDGVGGGTGGTGGNGGNGAIGGAGGDAGGSGNSGGNGGTGGKGG Rv3345c|M.tuberculosis_H37Rv GAGGTLAG--HGGNGGKGGNGGQGGIGGAG-------------ERGADGA MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK YVPFAVAAGVAAVWAQKYQDYTGSVAP----------------QPEWYGS Mvan_2685|M.vanbaalenii_PYR-1 YIPFAVAAGVAALWAKKYEAYTGAVAP----------------QPDWYGT MSMEG_3062|M.smegmatis_MC2_155 YIPFAVAAGTAALWAKKYQASVGDIAP----------------QPDWYHS MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 GVRASGLNTLAGNESGDGARIPMLPESWDGP------------------- MMAR_0884|M.marinum_M PTQETVAPLPTQQTVAPQPTIAPQPTQQAPEPPSGGSSGGSSGGGSSSGG Mb3541|M.bovis_AF2122/97 NAGAGGAAGSNGGTVGANGTGGDGGNGGAAGAATAG--SNGGAGTGSAGG Rv3345c|M.tuberculosis_H37Rv GPNANGANGENGGSGGNGGDGGAGGNGGAGGKAQAAGYTDGATGTGGDGG MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK SHSSSSGTAFSGGAGGGDFDSFESALSSSIGAYTASQASSSSSGGGSSSS Mvan_2685|M.vanbaalenii_PYR-1 STSSSTSRGISGG-GGADFDSFESALSSSIGAYTASQSSSSSSSGGGSSS MSMEG_3062|M.smegmatis_MC2_155 --SSDGGWKFSDGGGGTSFDSFESALSSSISAYTASQSSSSSSSGGGGSS MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M GSSSGGGSSSGGGSSSGGGSSSGGGSSSGGGSSSGGGSSSGGGSSSGGGS Mb3541|M.bovis_AF2122/97 NGGTGGRGGSGGAGGDGIGGVGGGKGGNGADGEVGGAGGAGGSGPNTSPG Rv3345c|M.tuberculosis_H37Rv NGGDGGKAGDGGAGENGLN-----------------------SGAMLPGG MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK SGGGGGGGGGGGGGSW---------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 SGGGGGGGGGGGGGSW---------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -GGGGGGGGGGGGGSW---------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M SSGRGSSSGGSSSGGHSSGGGS---------------------------- Mb3541|M.bovis_AF2122/97 GNGGQGGQGGSGGAGGAAGAGGAGGGANGTAGNGGQGGAGGTGGAGAASS Rv3345c|M.tuberculosis_H37Rv GTVGNPGTGGNGGNGGNAGVGGTGG----KAGTGSLTGLDGTDG-----I MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ATNGGSGGAGGTGGAGGTGGAGGDGVGGAGGGNGGHGGDAGDGGNGANGN Rv3345c|M.tuberculosis_H37Rv TPNGGNGGNGGNGGKGGTAGNG-SGAAGGNGGNGGSGLNGGDAGNGGNG- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 NRSSGSFLAAGGTGGAAGDGGQGGQGGAGGGAGGQGGAGGAGGTGGNGGN Rv3345c|M.tuberculosis_H37Rv ----GGALNQAGFFGTGGKGGNGGNGGAGMINGGLGGFGGAGGGG----- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ITGGTAGTAGAAGNGGAAGKGGAGGQGGTGGGTGGQGGAGGDGGAGGTGG Rv3345c|M.tuberculosis_H37Rv ------AVDVAATTGGAGGNGGAGGFASTG--LGGPGGAGGPGGAG---- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 DRTVGGGTVPAGSGGQGGNAGGGGAGGQGGADGGSGGDGGDAGTGGNGGN Rv3345c|M.tuberculosis_H37Rv -------DFASGVGGVGGAGGDGGAGGVGGF-GGQGGIGGEGRTGGNGGS MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGNRNSGNGTGGAGGNGGGGANGGAGGAGGSGGGTGGNGGAGGDAGDAGN Rv3345c|M.tuberculosis_H37Rv GGD---GGGGISLGGNGGLGGNGGVSETG--FGGAGGNGGYGGPGGPEGN MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGNGNGTGNGGNGGNGGIAGMGGNGGAGTGSGNGGNGGSGGNGGNAGMGG Rv3345c|M.tuberculosis_H37Rv GGLG---GNGGAGGNGGVSTTGGDGGAG------GKGGNGGDGGNVGLGG MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 NSGTGSGDGGAGGNGGAAGTGGTGGDGGLTGTGGTGGSGGTGGDGGNGGN Rv3345c|M.tuberculosis_H37Rv DAGSG----GAGGNGGIG-----------TDAGGAGGAGGAGGNGGS--- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGNGADNTANMTAQAGGDGGNGGDGGFGGGAGAGGGGLTAGANGTGGQGG Rv3345c|M.tuberculosis_H37Rv ----SKSTTTGNAGSGGAGGNGGTG-LNGAGGAGGAGGNAGVAGVSFGNA MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AGGDGGNGAIGGHGPLTDDPGGNGGTGGNGGTGGTGGAGIGSLGGGTGGD Rv3345c|M.tuberculosis_H37Rv VGGDGGNGGNGGHG-GDGTTGGAGGKGGNGSSGAASGSGVVNVTAGHGGN MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGNGGTGGNGGTGGEGGEVGGAGGTGGAAGNGGDGGTGGTGGGDGGAGGT Rv3345c|M.tuberculosis_H37Rv GGNGGNGGNGSAG-----AGGQGGAGGSAGNGGHG--GGATGGDGGNGGN MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GG-TGGTGGLGDPRVGGSGGDGGTGGSGGAAGNGGNGGNAGAGGNG-NGG Rv3345c|M.tuberculosis_H37Rv GGNSGNSTGVAGLAGGAAGAGGNGGGTSSAAGHGGSGGSGGSGTTGGAGA MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 TGGAGGIGGTGGNGGDAEPGVPPGAGGAGGAGTTGGKGGTGGNGSGTGSG Rv3345c|M.tuberculosis_H37Rv AGGNGGAGAGGGSLSTGQSGGPRRQRWCRWQRRRWLGRQRRRRWCRWQRR MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GTGGDGGTGGGGGNGGTGWNGGKGDTGSGGGAGDGGKAPAGGTGGAGGDG Rv3345c|M.tuberculosis_H37Rv CRRQRWRWRCRQRRLRRQWRQGRRRCRPWLHRRRGRQGRRWRQRRFQQRQ MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3732|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2685|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3062|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1280c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0118|M.avium_104 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GAGGKGGSGGV Rv3345c|M.tuberculosis_H37Rv RSRWQRR---- MUL_2783|M.ulcerans_Agy99 ----------- Mflv_3732|M.gilvum_PYR-GCK ----------- Mvan_2685|M.vanbaalenii_PYR-1 ----------- MSMEG_3062|M.smegmatis_MC2_155 ----------- MAB_1280c|M.abscessus_ATCC_199 ----------- MAV_0118|M.avium_104 ----------- MMAR_0884|M.marinum_M -----------