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RVARLLPLLLALLTVGLLGAPAASAEPPLRLPTYLTDRAGALDAAGESEVQTAIDQLYDDKRIRLWVVYV EDFSGQSAQTWAQTTFTRSDLGDQDVILAVATVDRAYALITPRGGAVRADIDEVRTQQVEPRLRAGDWAG AAVAAAQGLAGSGGGSVSWFGVIVALALIALALTILVLWQRRRRRKRREAEFAAAQRVDPSDPEALAAVP LDALDDLSRKIVVDVDNEVRTSESELALAVEEFGAQDTAAFTRAVEGAKTTLAQALNVRHILDDAVPETP MQRRDLLTRVIVAAAKADQELEAQREAFAALRDLVINAPSRLDTLTQQMIDLTTRITPAEQTLQQLKSQF AASALVSVSDNIDEARSRLAYADQSITTARTLVSRPAHRQGGLVDAIHSAEAALGQARTLLDAVDSASTD INRAVTGLPAVIADIQNGINSAGAQLAQGSVAVATELSDARDAAVQAVAEAQSSGETDPLGAFTRLTQAD ADLDRLLAEVAEERETAARLSRTFDQALFNAQSRVRAVSDYIDTRRGAIGPEARTRLAEAVRQLQAARDK QDTNLNEAIAHANGAAMLAAQAQSLANSDVTAAQRHFNGPYGGGGGGGQMGAVIGGILIGNVLSGVLRGG LGGGGFGGGFGGGGFGGGGGGGFSGGGGRF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2720 | - | - | 100% (661) | hypothetical protein Mflv_2720 |
| M. gilvum PYR-GCK | Mflv_5091 | - | 4e-07 | 36.63% (101) | triple helix repeat-containing collagen |
| M. gilvum PYR-GCK | Mflv_4210 | - | 1e-06 | 43.64% (55) | hypothetical protein Mflv_4210 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2374 | - | 0.0 | 56.42% (670) | transmembrane protein |
| M. tuberculosis H37Rv | Rv2345 | - | 0.0 | 56.42% (670) | transmembrane protein |
| M. leprae Br4923 | MLBr_01556 | infB | 3e-06 | 45.83% (72) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_1706c | - | 1e-165 | 49.18% (667) | hypothetical protein MAB_1706c |
| M. marinum M | MMAR_3652 | - | 0.0 | 56.87% (670) | hypothetical protein MMAR_3652 |
| M. avium 104 | MAV_2041 | - | 0.0 | 57.16% (670) | hypothetical protein MAV_2041 |
| M. smegmatis MC2 155 | MSMEG_4484 | - | 0.0 | 63.49% (682) | putative transmembrane protein |
| M. thermoresistible (build 8) | TH_1853 | - | 8e-09 | 24.89% (474) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1838 | - | 3e-09 | 52.46% (61) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_3816 | - | 0.0 | 88.50% (661) | hypothetical protein Mvan_3816 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2720|M.gilvum_PYR-GCK ------------------------------------MRVARLLP------
Mvan_3816|M.vanbaalenii_PYR-1 ---------------------------------MAVMRVARLLP------
MSMEG_4484|M.smegmatis_MC2_155 ------------------------------------MRIGRLFS------
Mb2374|M.bovis_AF2122/97 ------------------------------------MRLVRLLG------
Rv2345|M.tuberculosis_H37Rv ------------------------------------MRLVRLLG------
MMAR_3652|M.marinum_M ------------------------------------MRIPRLLG------
MAV_2041|M.avium_104 ------------------------------------MRTARLLA------
MAB_1706c|M.abscessus_ATCC_199 ------------------------------------MRLLRALAG-----
TH_1853|M.thermoresistible__bu ------------------------------------MRLHRLALTNYRGI
MUL_1838|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES
Mflv_2720|M.gilvum_PYR-GCK -------------LLLALLTVGL---LGAPAASAEPPLRLPTYLTDRAGA
Mvan_3816|M.vanbaalenii_PYR-1 -------------MLLAVLTLGL---LCAPGVAAEPPLRLPTYLTDNAGA
MSMEG_4484|M.smegmatis_MC2_155 -------------LLLAILTTGL---LVAPAAAAEPPLRLATQITDQAGA
Mb2374|M.bovis_AF2122/97 -------------MVLTILAAGL---LLGPPAGAQPPFRLSNYVTDNAGV
Rv2345|M.tuberculosis_H37Rv -------------MVLTILAAGL---LLGPPAGAQPPFRLSNYVTDNAGV
MMAR_3652|M.marinum_M -------------VILMIFTTGL---LLAPPSGAQPPFRLASYVTDNADA
MAV_2041|M.avium_104 -------------VLAALLTVGLSAGLLAPPAGAQPPLRLSDYLTDTAGV
MAB_1706c|M.abscessus_ATCC_199 -------------LLGVLIAVCAPTLLLAPVASADPPFRIPGYVTDRAGA
TH_1853|M.thermoresistible__bu ARREVEFPDRGVVVVSGANEIGKSSMIEALDLLFHAKDRSTKKEVKQVKP
MUL_1838|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP
Mflv_2720|M.gilvum_PYR-GCK LDAAGESEVQTAIDQ-----LYDD-------KRIRLWVVYVEDFSGQSAQ
Mvan_3816|M.vanbaalenii_PYR-1 LDTAGTAEVQAAIDR-----LYNE-------ERIRLWVVFVDDFSGQDAQ
MSMEG_4484|M.smegmatis_MC2_155 LSASQAASVQRALDR-----LYDD-------RRIKLWVVFVEDFSGQNYI
Mb2374|M.bovis_AF2122/97 LTSSGRTAVTAAVDR-----LYAD-------RRIRLWVVYVENFSGQSAL
Rv2345|M.tuberculosis_H37Rv LTSSGRTAVTAAVDR-----LYAD-------RRIRLWVVYVENFSGQSAL
MMAR_3652|M.marinum_M LTSSGRAKVTTAVNQ-----LYTE-------RHVRLWVVYVDDFSGQSAT
MAV_2041|M.avium_104 LSDSGRKAITTAVDK-----LYTD-------RHIRLWVVYVDTFSGQTAT
MAB_1706c|M.abscessus_ATCC_199 LKNP--AKVRAAVDQ-----LYDQ-------QHVRLWVVYVKDFEGTDPT
TH_1853|M.thermoresistible__bu THADVGAEITAEISTGPYRFVYHKRFHKKCATQLTILAPRREELSGDEAH
MUL_1838|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 VQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA
Mflv_2720|M.gilvum_PYR-GCK TWAQTTFTRS--------------------------DLGDQDVILAVATV
Mvan_3816|M.vanbaalenii_PYR-1 TWTQTTFARS--------------------------DLGNQDVILAVATV
MSMEG_4484|M.smegmatis_MC2_155 GWAQNTMRLS--------------------------DFGDDDALLAVATV
Mb2374|M.bovis_AF2122/97 NWAQRTTRTS--------------------------ELGNYDALLAVATT
Rv2345|M.tuberculosis_H37Rv NWAQRTTRTS--------------------------ELGNYDALLAVATT
MMAR_3652|M.marinum_M NWAQRTMQTS--------------------------ELGDYDAILAVATV
MAV_2041|M.avium_104 RWAQDTLRTS--------------------------DLGDYDALLAVATT
MAB_1706c|M.abscessus_ATCC_199 AWADKTIKAS--------------------------NLGDRDALLAVATE
TH_1853|M.thermoresistible__bu ERALAMLSETV-----------------------DMELWRTQRVLQAGST
MUL_1838|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 PHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRP
Mflv_2720|M.gilvum_PYR-GCK DRAYALITPRGG--AVRADIDEVRTQQVEPRLRA-------------GDW
Mvan_3816|M.vanbaalenii_PYR-1 DRAYALIAPKGG--AVRVDIDKVRTQQVEPLLRT-------------GDW
MSMEG_4484|M.smegmatis_MC2_155 DRAFAFQVPDTL--VDTARADDIRRNSIGPSLRR-------------EDW
Mb2374|M.bovis_AF2122/97 GREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHD-------------GDY
Rv2345|M.tuberculosis_H37Rv GREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHD-------------GDY
MMAR_3652|M.marinum_M ARSYAFLVPSTVDGITSSQVESLRRNKIEPKLRD-------------GDW
MAV_2041|M.avium_104 DRAYAFLVPPTIRGVNQSRVDALRHNKIEPALHD-------------GDW
MAB_1706c|M.abscessus_ATCC_199 ERSYAFQVASGIKNVSDSEIENLRTNTIEPALRT-------------SDW
TH_1853|M.thermoresistible__bu APVDLSGCDALSRALDAVAGEAVQTSGTEPLLIDRIDAEYRKYFTATGRP
MUL_1838|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 SASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNY
Mflv_2720|M.gilvum_PYR-GCK AGAAVAAAQGL--------AGSGGGSVSWFGVIVALALIALALTILVLWQ
Mvan_3816|M.vanbaalenii_PYR-1 AGAAVAAAEGL--------AGSGGGSVSWTGVLVVLAVIALALAALVLWQ
MSMEG_4484|M.smegmatis_MC2_155 AGAAIAAADQLNTE----PASATGGGVSWPALLIVLGIIAVLIGILWIWS
Mb2374|M.bovis_AF2122/97 SGAAVAAANGLN---------RSPSSSSRVVLLVTVGIIVIVVAVLLVVM
Rv2345|M.tuberculosis_H37Rv SGAAVAAANGLN---------RSPSSSSRVVLLVTVGIIVIVVAVLLVVM
MMAR_3652|M.marinum_M AGAAVAAADGLN---------KSPRPSGGIPLLVVLSVLAVAVAIFWIVM
MAV_2041|M.avium_104 SGAAVAAATGLD---------TAPGSSGRVILLATLAALLVAVMGLLLVM
MAB_1706c|M.abscessus_ATCC_199 DGAAIKTATGLES------AASSSASIPWKPVLGALAFGAVLVGAFMLFS
TH_1853|M.thermoresistible__bu TGEWLAATKRLQAA----DEQVARCAARVAEVEDAVRRHATLTESLAELE
MUL_1838|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 RGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPGGAPRR
Mflv_2720|M.gilvum_PYR-GCK --RRRRRKRREAEFAAAQRVD-PSDPEALAAVPLDALDDLSRKIVVDVDN
Mvan_3816|M.vanbaalenii_PYR-1 --RRRRRKRREAEFAAAQRVD-PSDANALAAVPLDALDELSRKIVVDVDN
MSMEG_4484|M.smegmatis_MC2_155 --RRRRAKRRKAEFEAAKRVD-PTDPDALASVPLEALDALSREIVVDVDN
Mb2374|M.bovis_AF2122/97 --RHRNRRRRADELAAARRVD-PTNVMALAAVPLQALDDLSRSMVVDVDN
Rv2345|M.tuberculosis_H37Rv --RHRNRRRRADELAAARRVD-PTNVMALAAVPLQALDDLSRSMVVDVDN
MMAR_3652|M.marinum_M --RYRASRRRTNALAAARRVD-PTDARALAAVPLDVLDELSRSMVVDVDN
MAV_2041|M.avium_104 --RYRGRRRRAAALAAARRLD-PTDLDALAALPLPTLDDLSRALVVDVDN
MAB_1706c|M.abscessus_ATCC_199 --WFRTRSRRRAEIEAAKGID-PSDAEALAKQPVTALDGLSKSIVVNVDN
TH_1853|M.thermoresistible__bu DGRRTADAQLAAAREAAEAVERLTRQLAEAQLAAEAAEATHTASVAALNE
MUL_1838|M.ulcerans_Agy99 ----------------------------MSAVLVVAPEALS---------
MLBr_01556|M.leprae_Br4923 GRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDA
. .
Mflv_2720|M.gilvum_PYR-GCK ---------------EVRTSESELALAVEEFGAQDTAAFTRAVEGAKTTL
Mvan_3816|M.vanbaalenii_PYR-1 ---------------ELRTSESELALAVEEFGEQDTAPFSRAVANARTTL
MSMEG_4484|M.smegmatis_MC2_155 ---------------AVRTSQAELELAVEEFGAKRTEPFTTAVANARKAL
Mb2374|M.bovis_AF2122/97 ---------------AVRTSTNELALAIEEFGERRTAPFTQAVNNAKAAL
Rv2345|M.tuberculosis_H37Rv ---------------AVRTSTNELALAIEEFGERRTAPFTQAVNNAKAAL
MMAR_3652|M.marinum_M ---------------AVRTSSNELAVAIDEFGEQRTAPFSQAVSNAKAAL
MAV_2041|M.avium_104 ---------------ALRTSANELDLAVAEFGDQRTQPFTQAVTNAKAAL
MAB_1706c|M.abscessus_ATCC_199 ---------------AVRTSEAELALAVEEFGTESTAPFQQAVDSAKKAL
TH_1853|M.thermoresistible__bu RRRLRAEIEERTAAVAALQPEVDAALEAEATAREVQQEADTAAERAREAA
MUL_1838|M.ulcerans_Agy99 ----------------------AAAANIAGIGSSLGAANAAAATPTTTVL
MLBr_01556|M.leprae_Br4923 N---------PAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVV
. .
Mflv_2720|M.gilvum_PYR-GCK AQALN--------VRHILDDAVPETPMQRRDLLTRVIVAAAKADQELEAQ
Mvan_3816|M.vanbaalenii_PYR-1 AQALN--------VRQILDDAVPETPMQRRDLLTRVIVAAAKADRELEAQ
MSMEG_4484|M.smegmatis_MC2_155 AQAFN--------VRQILDDDVPETPLQQRDLLTRVIVSAARADRELEAQ
Mb2374|M.bovis_AF2122/97 SQAFT--------VRQQLDDNTPETPAQRRELLTRVIVSAAHADRELASQ
Rv2345|M.tuberculosis_H37Rv SQAFT--------VRQQLDDNTPETPAQRRELLTRVIVSAAHADRELASQ
MMAR_3652|M.marinum_M SQAFS--------VRQQLDDSTPETPAQRRDLLTRVIVSAANADRELESQ
MAV_2041|M.avium_104 SQAFT--------VRQQLDDGMPETPAQRRELLTQVIVSAARADRELESQ
MAB_1706c|M.abscessus_ATCC_199 AQAFS--------VRKQLDDAIPETPLEQRRLLIDVITTAARADRTLEDQ
TH_1853|M.thermoresistible__bu DAARERVDTARQAVQRLADRAERDTLADRLRRIDAAATELARVDGELATL
MUL_1838|M.ulcerans_Agy99 AAGTD----------------------EISTTIATLFCGYARDYQNLSTQ
MLBr_01556|M.leprae_Br4923 SPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDT
: : . *
Mflv_2720|M.gilvum_PYR-GCK R-----------------------------------------EAFAALR-
Mvan_3816|M.vanbaalenii_PYR-1 R-----------------------------------------EAFAQLR-
MSMEG_4484|M.smegmatis_MC2_155 S-----------------------------------------AAFEQLR-
Mb2374|M.bovis_AF2122/97 T-----------------------------------------EAFEKLR-
Rv2345|M.tuberculosis_H37Rv T-----------------------------------------EAFEKLR-
MMAR_3652|M.marinum_M T-----------------------------------------EAFEKLR-
MAV_2041|M.avium_104 T-----------------------------------------EAFEGLR-
MAB_1706c|M.abscessus_ATCC_199 S-----------------------------------------SAFDALR-
TH_1853|M.thermoresistible__bu T-----------------------------------------VTEAALRQ
MUL_1838|M.ulcerans_Agy99 L-----------------------------------------ASFHQQF-
MLBr_01556|M.leprae_Br4923 IRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRA
:
Mflv_2720|M.gilvum_PYR-GCK ------DLVINAPSRLDTLTQQMIDLTTRITPAEQTLQQLKSQFAASALV
Mvan_3816|M.vanbaalenii_PYR-1 ------DLLINAPSRLDTLTQQMVDLTARLTPAEQTLEQLKSQFAETALV
MSMEG_4484|M.smegmatis_MC2_155 ------DLVINAPARLDLMTQQMVDLSARIETSQQTLAALHTQFDARALE
Mb2374|M.bovis_AF2122/97 ------DLVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMT
Rv2345|M.tuberculosis_H37Rv ------DLVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMT
MMAR_3652|M.marinum_M ------DLVINAPARLDLLTQRYIELTTRIAPTEQRLVELHDEFGATALS
MAV_2041|M.avium_104 ------DLVINAPSRLDGLTQQYVELTARIGPAEQQLAALHNEFSAAALT
MAB_1706c|M.abscessus_ATCC_199 ------NLVINAPAKLDTLTQQVVAVTARLPESERILGQLRTEFDAAALA
TH_1853|M.thermoresistible__bu I--EAAELAVERAAGQAELASAHIELTAAVDLELRVGDEQLTIPAGGSWT
MUL_1838|M.ulcerans_Agy99 ---------------LQALTGSANSYTAAEAANTNPLQALEQQLLAAINA
MLBr_01556|M.leprae_Br4923 RGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGAD
:
Mflv_2720|M.gilvum_PYR-GCK S--------------------------VSDNIDEARSRLAYADQSITTAR
Mvan_3816|M.vanbaalenii_PYR-1 S--------------------------VSDNIDEARQRLAFADQSITTAR
MSMEG_4484|M.smegmatis_MC2_155 S--------------------------VAGNVDTARERLAFADRNITTAR
Mb2374|M.bovis_AF2122/97 S--------------------------IAGNVTTATERLAFADRNISAAR
Rv2345|M.tuberculosis_H37Rv S--------------------------IAGNVTTATERLAFADRNISAAR
MMAR_3652|M.marinum_M S--------------------------ISANVASAHELLAFADSNISSAR
MAV_2041|M.avium_104 S--------------------------VSGNVTAAKERLAFADRNIGTAR
MAB_1706c|M.abscessus_ATCC_199 S--------------------------IGDNVAEATERVRFADSRITHGR
TH_1853|M.thermoresistible__bu AGATAPTEIELPGLLTARIVPGAPAAQMQETLDVARAALADALQHAGVAD
MUL_1838|M.ulcerans_Agy99 P-----------------------------------------------TQ
MLBr_01556|M.leprae_Br4923 PAKIRGQLTEYG--------------LVAEDFGGDTMFIDISAKVGTNIE
.
Mflv_2720|M.gilvum_PYR-GCK TLVSRPAH-RQGGLVDAIH---------SAEAALGQARTLLDAVDSASTD
Mvan_3816|M.vanbaalenii_PYR-1 GLVSRPAD-RQGGLVDAIH---------AAEAALGQARTLLDAVDSASTD
MSMEG_4484|M.smegmatis_MC2_155 GLVSRPAA-DQTGLVDAVR---------AAESALSQARTLLDAVDSASTD
Mb2374|M.bovis_AF2122/97 DLADQAVSGRQAGLVDAVR---------AAESALGQARALLDAVDSAATD
Rv2345|M.tuberculosis_H37Rv DLADQAVSGRQAGLVDAVR---------AAESALGQARALLDAVDSAATD
MMAR_3652|M.marinum_M ELSAKAVSGQQTGLVDAVR---------AAESALGQARSLLDAVDSAAGD
MAV_2041|M.avium_104 ELAGQAVSGQQGRLVDAVR---------AAESALGQARSLLDAVDHAAGD
MAB_1706c|M.abscessus_ATCC_199 ELAARALEGQQMSLVDAIR---------GAESALTQANALLDAIDNAANN
TH_1853|M.thermoresistible__bu VASARSQVERRRELSTARETFAATVVALTGEDTLERLRARLAELDAAASD
MUL_1838|M.ulcerans_Agy99 TLLGRPLIGNGANGAPGQN---------GADGGLLWGTGGTGDATHPAGG
MLBr_01556|M.leprae_Br4923 ALLEAVLLTADAALDLRANSG-MEAQGVAIEAHLDRGRGPVATVLVQRGT
. : *
Mflv_2720|M.gilvum_PYR-GCK IN--------RAVTGLPAVIADIQNGINSAGAQLAQG---SVAVATELSD
Mvan_3816|M.vanbaalenii_PYR-1 IN--------RAVTGLPAVIADIQNGINQAGAQLAQG---NVAVATELST
MSMEG_4484|M.smegmatis_MC2_155 IN--------RALAGLPAAVADIEAGIEQANDLLAQP---DTPQADKLAT
Mb2374|M.bovis_AF2122/97 IR--------HAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIA
Rv2345|M.tuberculosis_H37Rv IR--------HAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIA
MMAR_3652|M.marinum_M IR--------HAVATMPSVLADIQAGIQHANEQLQKSPANKSAYAAELIA
MAV_2041|M.avium_104 IR--------HAIDQLPSAMADIENDIKRAAELLAATRDTKSGHAAELAA
MAB_1706c|M.abscessus_ATCC_199 IR--------HAIDSLAASIADTKSDIAQAEEFQKQG---RLPSSEELTK
TH_1853|M.thermoresistible__bu DTG------ELGVDDAQAELTAAERAYQQAHTDCETHRKAAVLAARRLAE
MUL_1838|M.ulcerans_Agy99 NG------------GNAGLIGNGGAGGAGKDGPLQSN-------GGNAGH
MLBr_01556|M.leprae_Br4923 LRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDN
:
Mflv_2720|M.gilvum_PYR-GCK ARDAAVQAVAEAQSS-GETDPLGAFTRLTQADADLDRLLAEVAEERETAA
Mvan_3816|M.vanbaalenii_PYR-1 ARDAAVQAVSQAQST-GNSDPLGAFTRLTQADADLDRLLAEVAEERETAE
MSMEG_4484|M.smegmatis_MC2_155 ARDAAVQAAGEAKSN-GTADPLGTFTRLTQADADLDQLLATVHEQREAAE
Mb2374|M.bovis_AF2122/97 ARDAAARALDRAR---GAADPLTAFDQLTKVDADLDRLLATLAEEQATAD
Rv2345|M.tuberculosis_H37Rv ARDAAARALDRAR---GAADPLTAFDQLTKVDADLDRLLATLAEEQATAD
MMAR_3652|M.marinum_M ARDAAARAVDNARVT-GAADPLSAFAQLTTADADLDRLLAAIAQEQANAE
MAV_2041|M.avium_104 ARDAATRAVEGARAG-APDDPLGAFGQLTKADAGLNAVLAAVAQERAAAE
MAB_1706c|M.abscessus_ATCC_199 AHDAAVAAVADAERI-GATDPLTAFTHLAAADAQLDKLLAAAQEERAAAE
TH_1853|M.thermoresistible__bu KSQTAAALREKLTAARTELDTAAARLAAQRADVDDETLVVRAAAHGEEAE
MUL_1838|M.ulcerans_Agy99 GGDGAAGGEGGWFSADGGAGGSGGHGGHGGKGGAEGSGFGSGGSGGDGGV
MLBr_01556|M.leprae_Br4923 FLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNL
Mflv_2720|M.gilvum_PYR-GCK RLSR-------TFDQALFNAQSRVRAVSDYIDTRRGAIGPEARTRLAEAV
Mvan_3816|M.vanbaalenii_PYR-1 RLSR-------TFDQALFNAQSRVRAVSDYIDTRRGAIGPEARTRLAEAV
MSMEG_4484|M.smegmatis_MC2_155 RLAR-------TLEQAIFTAESRITAVSDYIETRRGSIGPEARTRLAEAT
Mb2374|M.bovis_AF2122/97 RLNR-------SLEQALFTAESRVRAVSEYIDTRRGSIGPEARTRLAEAK
Rv2345|M.tuberculosis_H37Rv RLNR-------SLEQALFTAESRVRAVSEYIDTRRGSIGPEARTRLAEAK
MMAR_3652|M.marinum_M HLRR-------SLEQALFTAESRIRAVSDYIDTRRGSIGPEARTRLAEAG
MAV_2041|M.avium_104 RLAR-------SLEQALFTAQSRVRAVSDYIDTRRGSIGPEARTRLAEAQ
MAB_1706c|M.abscessus_ATCC_199 RRAR-------VLDQALVAARQRLDAVNQYIGLHRGAVGARTRWNLDEAQ
TH_1853|M.thermoresistible__bu RAAVRVA----QLNAELSAAQPDQVAAALDTAARHAETVHAEHRRTADAL
MUL_1838|M.ulcerans_Agy99 AAMG-------GSGGWFSGNGGAGGSGGSGGDAGNGGNGSGPSTGGDGGD
MLBr_01556|M.leprae_Br4923 ILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGG-ITETNVNLASAS
: . .
Mflv_2720|M.gilvum_PYR-GCK RQLQAARDKQDTNLNEAIAHANGAAMLAAQAQSLANSDVTAAQRHFNGPY
Mvan_3816|M.vanbaalenii_PYR-1 RQLQAARDKRETNLNEAIAHANGAAMLAAQAQSLANSDVTAAQRHFSGPY
MSMEG_4484|M.smegmatis_MC2_155 RQLEAARAKRSTNPNEAVAHANGASTLAAQAQSLANDDVRAAQRSYTSHH
Mb2374|M.bovis_AF2122/97 RQLEAAHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRAYT---
Rv2345|M.tuberculosis_H37Rv RQLEAAHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRAYT---
MMAR_3652|M.marinum_M RRLDAAQSYRSTNPTEAIAQANAASTLAANAQSLANSDVQAAQRAYT---
MAV_2041|M.avium_104 RHLHAAADRRATDPADAIAHANAASTLAAEAQSLANGDVQAARRAYP---
MAB_1706c|M.abscessus_ATCC_199 RRLAAAEQSRASNPSDAILFANGAAELATQAQYSAQQEVQSAQRYYG---
TH_1853|M.thermoresistible__bu RELNAQLEVYGSEGRKGELDAAKAEREQAEAEFLRIGRLARAVKLLRETM
MUL_1838|M.ulcerans_Agy99 GGNGAAGGVGATLIGNGAAGGAGGGGGTGGAGGHGGGGGTD---------
MLBr_01556|M.leprae_Br4923 DAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPI
.
Mflv_2720|M.gilvum_PYR-GCK GGGGGGG------QMGAVIG---GILIGNVLSGVLRGGLGG---------
Mvan_3816|M.vanbaalenii_PYR-1 GGGGGG-------QMGAVIG---GILIGNVLSGALRGGFGG---------
MSMEG_4484|M.smegmatis_MC2_155 GGGGAD--------MGAVLG---GIIIGNVLRGGFGGGGGY---------
Mb2374|M.bovis_AF2122/97 RRGGNN--------AGAILG---GIIIGDLLSGGTRGGLG----------
Rv2345|M.tuberculosis_H37Rv RRGGNN--------AGAILG---GIIIGDLLSGGTRGGLG----------
MMAR_3652|M.marinum_M RQGGNN--------TGAVLG---GIIIGDLLSGGMRGGFG----------
MAV_2041|M.avium_104 RGGGGD--------MGAMLG---GIIIGDLLSSGMRGGFG----------
MAB_1706c|M.abscessus_ATCC_199 NGYGGYS------VAGDVAGNVAGAVIGGILRGMLSGGAGH---------
TH_1853|M.thermoresistible__bu LRHRDASRRRYVDPFRAEVERLGRIVFGDSFEVEIDSDLCIRSRTLAGRT
MUL_1838|M.ulcerans_Agy99 -GGGGD---------GAMGG------AAQLIGDGGNGGAGG---------
MLBr_01556|M.leprae_Br4923 YEENQLG---RAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIV
. :
Mflv_2720|M.gilvum_PYR-GCK -------GGFGGGFG--GGGFGGG--------------------------
Mvan_3816|M.vanbaalenii_PYR-1 -------GGFGGGFG--GGGFGGG--------------------------
MSMEG_4484|M.smegmatis_MC2_155 -------GGYGGGFGGFGGGFGGGRSS-------------GRPTSYGGSS
Mb2374|M.bovis_AF2122/97 -------GWIPTSFGGSSNAPGSS--------------------------
Rv2345|M.tuberculosis_H37Rv -------GWIPTSFGGSSNAPGSS--------------------------
MMAR_3652|M.marinum_M -------GWSPTSFGGSSGSSGDS--------------------------
MAV_2041|M.avium_104 -------GWSPASFGGSTSSSG----------------------------
MAB_1706c|M.abscessus_ATCC_199 -------HSSWSGSGSSSYGGSSR--------------------------
TH_1853|M.thermoresistible__bu VDYESLSGGAKEQLGIVARLAGAALVARDDTVPVVIDDALGFTDAERLVK
MUL_1838|M.ulcerans_Agy99 -------SGTPDGSGGAGGTAGRL--------------------------
MLBr_01556|M.leprae_Br4923 VTDNLTVTSLRREKDDVTEVREGFECG-----------------------
.
Mflv_2720|M.gilvum_PYR-GCK --GGGGFSGGGGRF-----------------------
Mvan_3816|M.vanbaalenii_PYR-1 --GGG-FSGGGGRF-----------------------
MSMEG_4484|M.smegmatis_MC2_155 HSSGRNYGGGGGRF-----------------------
Mb2374|M.bovis_AF2122/97 --PDGGFLGGGGRF-----------------------
Rv2345|M.tuberculosis_H37Rv --PDGGFLGGGGRF-----------------------
MMAR_3652|M.marinum_M --SGGGFLGGGGRF-----------------------
MAV_2041|M.avium_104 ----GGVLGGGGRF-----------------------
MAB_1706c|M.abscessus_ATCC_199 -SSGSSFRGGGGRF-----------------------
TH_1853|M.thermoresistible__bu MGAVFDAVGGDGQVIVLTCSPDRYAGISDAHRIELTA
MUL_1838|M.ulcerans_Agy99 ----AGAAGTHG-------------------------
MLBr_01556|M.leprae_Br4923 -MTLGYSDIKEGDVIESYELVEKQRA-----------
*