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M. bovis AF2122 / 97 Mb3541 (PE_PGRS55)

annotation: PE-PGRS family protein
coordinates: 3883854 - 3889670
length: 1938
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Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3541PE_PGRS55-100% (1938)PE-PGRS family protein
M. bovis AF2122 / 97Mb3538PE_PGRS540.054.84% (1528) PE-PGRS family protein
M. bovis AF2122 / 97Mb1485cPE_PGRS270.048.78% (1470) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5091-0.051.18% (803) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3512PE_PGRS560.076.97% (1094) PE-PGRS family protein
M. leprae Br4923MLBr_01183-3e-1135.87% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-3e-5931.73% (561) hypothetical protein MAB_4284c
M. marinum MMMAR_1594-0.054.41% (2235) PE-PGRS family protein
M. avium 104MAV_4827-5e-2744.38% (169) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-18041.47% (1073) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-5145.27% (296) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.049.05% (1162) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-0.050.19% (805) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb3541|M.bovis_AF2122/97            MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSAR
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               MSYMSISPEIVSSAAGELANIGSTVSAANAAAAVATTELLAAGSDEVSTR
MUL_4367|M.ulcerans_Agy99           MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSAA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -----MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            IAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEAT------N
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               IAALFGANGVEYQAISAQIASFHDRFVAALNTGTSSYVWAEAT------N
MUL_4367|M.ulcerans_Agy99           IAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQE
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      LAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            VEQNLLNLINAPTQTLLGRPLIGDGANATTPGGAGGDGGLLFGSGGNGAP
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               VEQNLLNAVNAPVQTLLGRPLIGNGANATTPGGAGGDGGLLYGSGGNGAA
MUL_4367|M.ulcerans_Agy99           LEQQALGVVNAPSMALFGRPSIGN--------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GAPGQAGGAGGSAGLLGNGGSGGAGGTG-APGGNGGNAGWLYGRGGVGGA
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GAPGQAGGAGGSAGLWGNGGSGGSGGIGGGTGGNGGSGGWLLGRGGIGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      LIPNAPTEPADMPGVWAVMAWAR---------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GGIGGGTGGAGGHAWLFGHGGTG---------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGTGGGSGGSGGGAWLFGDGGAGGMGGTGGSGGGFGGTGGHGGLLYGNGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               AGGAGATGQTGGSGGWAALWGRGGAGGAGGDNGGFAGGDGGHGGLLCGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ---GIGGGPGGNGGWLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGG
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GDGGLGGGDGGNAGWLLGFGGHGGAGGDGGFAGGEGGNGGWLLGFGGHGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            AGGTGGGAGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGGWLLGNGGN
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               TGGIGGGTGGAGGAGGLVMGFGGHGGTGGIGGGAGGAGGQAALLFGHGGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGT
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGAGGVGTAGGAGGAGGDGGNPGWLLGRAGSGGDGGAGGAATTVGATGGV
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GGDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGG------AGGAG
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGHGGAGGRGGVLMGGGAGGDGGAGGAGADGSNGVGDGGNGATGGGGGVG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GNGGAGGQAALLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGG
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GDGGAGGQAALLFGCGGTGGHAGAGGAGGGGGTGADS----LTGIGGAGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            TGGDGGAPGNGGAGGAGQLLSHSGVAGASGKGGAGGTGGNGGAGSAGADA
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               DGGIGGASGQAGAGGAGNLFSHNGSRGHAGIGGDGGDGGTGGTGGEGTDA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            PAGSGAMGSTGFAGGAGGDGGNGGGSGA----------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               AAGSGLTGGTGYAGGTGGTGGAGGNSGLGGTNGSGGHGGTGGTGGTGGTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GSGADNTTGIGGDGGQGGTGGDAGAGGAGGNSGFGGTGGTTGTHGDAGIG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ------------------------------------------------SQ
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GDGGDGGTGGTGGQGTDAAAGTGLTGGTGYAGGTGGAGGAGGNSGLGGTN
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GNGGNGGNGGTGGKGGTGGAGMNSLDP-----------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GSGGHGGTGGTGGTGGTGGSGADALDGSGASGHDGGDSGAGGDGGTGGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GNAGTGAGAAGNNGDGGAGGTGGNSGAQAGDGGAGAANTTIGGTGGAGGS
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGNIGAGGAGGQGGAAGTTSGVGGASGTSGTSGQSIGTGGDGGAGGDGGT
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GTTGADAAAGSGLGGDIGGTGGAGGAGGTGGSGGTDSGVGGSGGVGGVGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ---------------LLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAG
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               TGGQGGAGSDNSANAGVAGGAGGQGGAGGTGGAAGSGGTGSVAGADGSSG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            NGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTG
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               DGGTGGLGGDGGAGGTGSMGAVDGGTGGQGASGGAGGQGGTGGAAGAGTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAG
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GIQGAGGQGGTGGTGGTGGTGGDGAESTDPSLAGQAGGQGGTGGTGGAAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            AGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGA
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               QGGTGSVTGAEGSAGDGGTGGLGGDGGTGADNTTTVSAGAQGATGGTGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQ
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               GGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGAESTDPTLAAQ
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------RQPMYSDPAMRTTVNPQAQ
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            DGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTT
Rv3512|M.tuberculosis_H37Rv         ---------------------PQGADGNAGNGGDGGVGGNGGNGADNTTT
MMAR_1594|M.marinum_M               AGGQGGTGGTGGAAGQGGTGSTMGAEGSSGDGGTGGLGGDGGAGADNTTT
MUL_4367|M.ulcerans_Agy99           -----------------------GVDGVAGTGQAGGAGGILWGNGGNGGL
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP
MSMEG_0868|M.smegmatis_MC2_155      LPVPTVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTIS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------MSIIDFILNLFRDPVEAASYVADPEAALANA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEE
                                                                                      

Mb3541|M.bovis_AF2122/97            AAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGG--NGGNGGTGGKG
Rv3512|M.tuberculosis_H37Rv         AAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGG--NGGNGGTGGKG
MMAR_1594|M.marinum_M               VSTGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGG--QGGTGGTGGTG
MUL_4367|M.ulcerans_Agy99           GAAGANGGAGGSAGLIGTGGVGGAGGVGAAGMTGGSG--GAG-GGGGWLW
Mflv_5091|M.gilvum_PYR-GCK          --MVTFGGGATPTPTSLGAAAVDLSGT-SCGLICNGQ--DGTGQNGGILF
Mvan_1264|M.vanbaalenii_PYR-1       WYVVSFGGSGAPTPNNLAASLVDLSGT-SCGLICNGQ--DGTGQNGGILF
MSMEG_0868|M.smegmatis_MC2_155      GQYLIGNGINGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLF
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNP-IHDLSGNLQNYY
MLBr_01183|M.leprae_Br4923          ----------------------------MPLFLNAEP--QALTAAANTLE
MAV_4827|M.avium_104                DAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLE
                                                                                      

Mb3541|M.bovis_AF2122/97            GTGGDG-------ALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG
Rv3512|M.tuberculosis_H37Rv         GTGGDG-------ALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG
MMAR_1594|M.marinum_M               GSGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDG
MUL_4367|M.ulcerans_Agy99           GAGGSG-----------GAAGAGGSGGSGG--WLWGNAGQTAGAGVGGAG
Mflv_5091|M.gilvum_PYR-GCK          GNGGSG----------WNSDVVGMDGGNGGNGGLFG--------GNGGNG
Mvan_1264|M.vanbaalenii_PYR-1       GNGGSG----------WNSEIAGVSGGNGGNAGLFG--------GNGGNG
MSMEG_0868|M.smegmatis_MC2_155      GNGGNG-----------GVGWAGLDGGNGGSGGLLM--------GIGGAG
TH_3810|M.thermoresistible__bu      ---------------------VDGDGGSGGRTGLFS------KLSRGGDG
MAB_4284c|M.abscessus_ATCC_199      AAQPDG------------PSILSPSLLSPRDNDFLSHNDTDFASHNPIAS
MLBr_01183|M.leprae_Br4923          GLSAAT---------------VASNAAAAQLTTEIA--------PPAADD
MAV_4827|M.avium_104                AAALRD----------------ALAARRIDNVMLVSAFLAAAALAQNVGG
                                                                                     .

Mb3541|M.bovis_AF2122/97            GKGGNGGIGAAGTTG-----PVGTGASGGTGGSGGAGGTGGDGG--AANG
Rv3512|M.tuberculosis_H37Rv         GKGGNGGIGAAGTTG-----PVGTGASGGTGGSGGAGGTGGDGG--AANG
MMAR_1594|M.marinum_M               GTGGLGGDGGEGGQGTTAWNPGDTGGQGASGGAGGTGGTGGAAG--TGTG
MUL_4367|M.ulcerans_Agy99           GAGGAGDAGDQGVSG------VAPGEAGAVGFAGGAGGAGGAGG--NGVG
Mflv_5091|M.gilvum_PYR-GCK          GNGLGGGNGGNG------------GNAGAFALFG-NGGNGGNGG--VGVV
Mvan_1264|M.vanbaalenii_PYR-1       GNGLGSGDGGNG------------GDAGLFSLFG-RGGNGGNGG--VGIA
MSMEG_0868|M.smegmatis_MC2_155      GAGGVGADGTSAHVDG-----GTGGTGGTGGGTGGTGGIGGTGGGLFGLL
TH_3810|M.thermoresistible__bu      GDGGLG-------------------------------GNGGHGG------
MAB_4284c|M.abscessus_ATCC_199      GNQVMSPSGNVDSFN-------------RGPLLDLSFGDLQFGNRDTTAI
MLBr_01183|M.leprae_Br4923          VSILLAHF------------------------------FSGHGR------
MAV_4827|M.avium_104                AMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLS
                                                                              .       

Mb3541|M.bovis_AF2122/97            G-TAGAGGAGGNGGKGGDGGAG-------VTSSTAGNSGGAGGSGGKGGD
Rv3512|M.tuberculosis_H37Rv         G-TAGAGGAGGNGGKGGDGGAG-------VTSSTAGNSGGAGGSGGKGGD
MMAR_1594|M.marinum_M               G-IQGAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGA
MUL_4367|M.ulcerans_Agy99           GGVNGAGGAGGAGGVGGGGGAGASG----VGAGVAGGDGGTGGAGGAAGV
Mflv_5091|M.gilvum_PYR-GCK          G---ATGAVGAPGVAGATGATG-------VTSGVVGGNGEDAVGYGATGA
Mvan_1264|M.vanbaalenii_PYR-1       G---ATGAVGAPGVAGATGATG-------VTSNVTGGNGADAVGYGATGA
MSMEG_0868|M.smegmatis_MC2_155      G-HSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGT
TH_3810|M.thermoresistible__bu      G--TGIISLLSLAGNGGNGGNG---------YRTTDNNALDGGHGGNGGN
MAB_4284c|M.abscessus_ATCC_199      G--DGAVAVGGSNSGPIASGQGS-----TAVNGDVRDSNIINADHGSNVG
MLBr_01183|M.leprae_Br4923          -------QYQAHASQGATNHQD-------LIQSLLTSSSAYAGTETANHD
MAV_4827|M.avium_104                AMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETAL
                                              .          .                            

Mb3541|M.bovis_AF2122/97            AGAGGAGATPGANGIAGNGGDG---GDGAAGAVGISGATGAGDGGHGGTG
Rv3512|M.tuberculosis_H37Rv         AGAGGAGATPGANGIAGNGGDG---GDGAAGAVGISGATGAGDGGHGGTG
MMAR_1594|M.marinum_M               AGTGGTGSTMGAEGSSGDGGSGGLGGDGGAGGQGTTGTAGAGTGGQGASG
MUL_4367|M.ulcerans_Agy99           GGAAGTGGTGGAAGVAGTGGDG---GDGGAGGAGSDASLAGQAGFAGGSG
Mflv_5091|M.gilvum_PYR-GCK          AGAAGAAGAAGAAGAVG--------SAGAAGEAGETGTWGN-AGLPGKAG
Mvan_1264|M.vanbaalenii_PYR-1       AGAAGAAGAAGKAGAVG--------SAGTAGSAGAPGVWGN-AGLPGAAG
MSMEG_0868|M.smegmatis_MC2_155      GGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTT
TH_3810|M.thermoresistible__bu      VGFFSLFN------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRS
MLBr_01183|M.leprae_Br4923          SL------------------------------------------------
MAV_4827|M.avium_104                ARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPG
                                                                                      

Mb3541|M.bovis_AF2122/97            GAGGNGGTGGAGGSGIDGVG--GGTGGTGGNGGNGAIGGAGGD-------
Rv3512|M.tuberculosis_H37Rv         AAGGNGGTGGAGGSGIDGVG--GGTGGTGGNGGNGAIGGAGGD-------
MMAR_1594|M.marinum_M               GAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQI
MUL_4367|M.ulcerans_Agy99           GAGGVGGSAGAGG-----------VNGSGGDGGAGAAGGAGGA-------
Mflv_5091|M.gilvum_PYR-GCK          DAGGAGAVG-----------------AAGAAGTVGTAGATGGT-------
Mvan_1264|M.vanbaalenii_PYR-1       AAGGAGAIG-----------------TAGVAGAAGTAGATGGT-------
MSMEG_0868|M.smegmatis_MC2_155      AAGGNGGTGGTGR---------VIAEGTGSTAEGTATGGDGGHSTG----
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TNIGSGNTTN-------------TEIGSHNQANIGTSTSAGGS-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                DDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSG-------
                                                                                      

Mb3541|M.bovis_AF2122/97            --AGGSGNSGGNG-------------------------------------
Rv3512|M.tuberculosis_H37Rv         --AGGSGNSGGNG-------------------------------------
MMAR_1594|M.marinum_M               AQAGGQGGTGGTGGAAGQGGTGSTIGSAGTAGDGGTGGLGGDGGTGADNT
MUL_4367|M.ulcerans_Agy99           -----SATVAGSG-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ------------GTGGKGGNAGAGGAAGS-------------NGGTVGAN
Rv3512|M.tuberculosis_H37Rv         ------------GIGGKGGNAGAGGAAGS-------------NGGTVGAN
MMAR_1594|M.marinum_M               TTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQG
MUL_4367|M.ulcerans_Agy99           ---------------GVGGDGGAGGAAGG----------------GVGAA
Mflv_5091|M.gilvum_PYR-GCK          ---------------GTGANGGAG-----------------------GVG
Mvan_1264|M.vanbaalenii_PYR-1       ---------------GVGGNGGAG-----------------------QAG
MSMEG_0868|M.smegmatis_MC2_155      --------------TGIGGNGGIGSVYAYG------------NNGAVSGT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------------A
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GTGGD-------------------GGNGGAAG-------AATAGSNGGAG
Rv3512|M.tuberculosis_H37Rv         GTGGD-------------------GGNGGAAG-------AATAGSNGGAG
MMAR_1594|M.marinum_M               GTGGDGADSTDPTLAGQAGGQGGTGGTGGAAGQGGTGSTSGSEGSSGDGG
MUL_4367|M.ulcerans_Agy99           SLGGD-------------------GGHAGAGG-------AGGEGLSGGFN
Mflv_5091|M.gilvum_PYR-GCK          GVGGT--------------------GAAGAAG------GAGGLGETG---
Mvan_1264|M.vanbaalenii_PYR-1       GIGGT--------------------GAAGAAG------QAGTAGETG---
MSMEG_0868|M.smegmatis_MC2_155      ATGGR--------------------GGDGIDG------GTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AVGGN----------------------------------AGLAGNAG---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            TG------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         TG------------------------------------------------
MMAR_1594|M.marinum_M               TGGLGGDGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGTQ
MUL_4367|M.ulcerans_Agy99           TG------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      SG-----------------------------------------------A
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            SAGGNGGTGGRGGSGGAGGD------------------------------
Rv3512|M.tuberculosis_H37Rv         SAGGNGGTGGRGGSGGAGGD------------------------------
MMAR_1594|M.marinum_M               GAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGQG
MUL_4367|M.ulcerans_Agy99           ---AAGGIGGAGGAGGTGGD------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ---TTGGAGGVGGQGTAGGT------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---VTGGVGGIGGQGTEGGT------------------------------
MSMEG_0868|M.smegmatis_MC2_155      DGEATGISAGGDGGSATGADS-----------------------------
TH_3810|M.thermoresistible__bu      ----LGGAGGWGGSGVDGVD------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----LAGNAGLAGNAGLAGN------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -LAVVGISAVLALEIALAIG------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ---------------GIGGVGG---------------GKGGNGADGEVGG
Rv3512|M.tuberculosis_H37Rv         ---------------GIGGVGG---------------GKGGNGADGEVGG
MMAR_1594|M.marinum_M               GTGSTMGSDGSSGDGGTGGLGGDGGEGGQGTTGTAGAGTGGQGASGGAGG
MUL_4367|M.ulcerans_Agy99           ----------------SGGVGG----------------VNGDGGAGGGGG
Mflv_5091|M.gilvum_PYR-GCK          -----------------GGVGG----------------IGGAGSTGAVGG
Mvan_1264|M.vanbaalenii_PYR-1       -----------------GGVGG----------------VGGVGATGGAGG
MSMEG_0868|M.smegmatis_MC2_155      ----------------LGGRGG---------------TSWVQAGYGPTTG
TH_3810|M.thermoresistible__bu      ------------------VVGG--------------------NPDGGTPG
MAB_4284c|M.abscessus_ATCC_199      -----------------AGLAG------------------NAGLAGNAGL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------IRTTGTVAL
                                                                                      

Mb3541|M.bovis_AF2122/97            AGGAG-----------GSGPNTSPGGNGGQG-------------------
Rv3512|M.tuberculosis_H37Rv         AGGAG-----------GSGPNTSPGGNGGQG-------------------
MMAR_1594|M.marinum_M               TGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGADSTDPTLAGQAG
MUL_4367|M.ulcerans_Agy99           RGGDG-------------GSSTSTSGVGGAG-------------------
Mflv_5091|M.gilvum_PYR-GCK          VGGKG-----------IQGGQGLQGGKGGDG-------------------
Mvan_1264|M.vanbaalenii_PYR-1       VGGKG-----------IQGGQGLQGGQGGDG-------------------
MSMEG_0868|M.smegmatis_MC2_155      GKASG-------------TAKAGHGGKASDG-------------------
TH_3810|M.thermoresistible__bu      AHGES-------------HTPGVYTDRQGED-------------------
MAB_4284c|M.abscessus_ATCC_199      AGNAG------------LAGNAGLAGNAGLA-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                QPTPN-------------QHLIVPTEQAPAP-------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GQGGSGGAGGAAGAGGAG--GGANGTAGNGGQGGAGGTGGAGAASSATN-
Rv3512|M.tuberculosis_H37Rv         GQGGSGGAGGAAGAGGAG--GGANGTAGNGGQGGAGGTGGAGAASSATN-
MMAR_1594|M.marinum_M               GQGGTGGTGGAAGQGGTGSVAGTDGSSGDGGTGGLGGHGGAGADNTTTVS
MUL_4367|M.ulcerans_Agy99           ---GAGGNGGNAGFGVSA-----------GGTGGSAGDGGAG--------
Mflv_5091|M.gilvum_PYR-GCK          ---GAGGKGGDADSMGSA-----------GATGGKGGNGGNG--------
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGGTGGDATSMGEA-----------GATGGKGGNGGNG--------
MSMEG_0868|M.smegmatis_MC2_155      ---GKGGNGGDALVMAAG------ATGVATGNTAIGGNGGAAS-------
TH_3810|M.thermoresistible__bu      ---GEDGTG--------------------TGIGGRGGNGGSS--------
MAB_4284c|M.abscessus_ATCC_199      ---GNAGLAGNAGLAGNAG---------LAGNAGLAGNAGLAG-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --PPVQASAPQPKISVPEP---------VAAPKPLSPPVAAPLPAAPPP-
                                                                                      

Mb3541|M.bovis_AF2122/97            ----GGSGGAGGTGGAGGTGGAGGDGVGGAG-------------------
Rv3512|M.tuberculosis_H37Rv         ----GGSGGAGGTGGDGGSGGAGG--TGG---------------------
MMAR_1594|M.marinum_M               AGAQGATGGTGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGG
MUL_4367|M.ulcerans_Agy99           ----GGAGGVDGVGGASGNGGAAG--------------------------
Mflv_5091|M.gilvum_PYR-GCK          -----GRGGLFGKGGNAGNGADGG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -----GRGSLFGRGGNAGNGGNGG--------------------------
MSMEG_0868|M.smegmatis_MC2_155      -----ANGAVGGNGGFTNIAAIHG--------------------------
TH_3810|M.thermoresistible__bu      ----------SGTHPMAEDG------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------NAGLAGNAGLAGNAGLAG--------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----AAPPLPEAPPIPAAPPVVP--------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ---------------GGNGGHGGDAGDGGNGANGNNRSSGSFLAAGGTGG
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------AGGTGG
MMAR_1594|M.marinum_M               DGTDNSTTPGAAGGAGGQGGTGGTGGAAGQGGTGSTSGSAGSSGDGGTGG
MUL_4367|M.ulcerans_Agy99           -----------------------------------------------AGG
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------------------TGG
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------------------TGG
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------------------------SITDS
TH_3810|M.thermoresistible__bu      -----------------------------------------------EHV
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------------NAGL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------------------------------VPVV
                                                                                      

Mb3541|M.bovis_AF2122/97            AAGDGGQGGQ----------------GGAGG----------------GAG
Rv3512|M.tuberculosis_H37Rv         AAGDGGQGGQ----------------GGAGG----------------GAG
MMAR_1594|M.marinum_M               LGGDGGEGGQGTTGTAGAGTGGQGASGGAGGQGGTGGAAGTGTGGTQGAG
MUL_4367|M.ulcerans_Agy99           AGGSG-----------------------------------------IGAG
Mflv_5091|M.gilvum_PYR-GCK          AGGAG------------------------------------------GTG
Mvan_1264|M.vanbaalenii_PYR-1       NGGNG------------------------------------------GTG
MSMEG_0868|M.smegmatis_MC2_155      SATSG-----------------------------------------HGGA
TH_3810|M.thermoresistible__bu      KALDG------------------------------------------RPG
MAB_4284c|M.abscessus_ATCC_199      AGNAG----------------------------------------LAGNA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPPVP-----------------------------------------VPVP
                                                                                      

Mb3541|M.bovis_AF2122/97            GQGGAGGAGGTGGNGGN---------------------------------
Rv3512|M.tuberculosis_H37Rv         GQGGAGGAGGTGGNGGN---------------------------------
MMAR_1594|M.marinum_M               GQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGS
MUL_4367|M.ulcerans_Agy99           IDGGAGGAGGTGG-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GTGGAGGTGGTGG-------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GTGGNGGTGGTGG-------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AQGGNGGNGGNGWVQAYDPNGPAG--------------------------
TH_3810|M.thermoresistible__bu      LDGGNGSHGGNGG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GLAGNAAVAGNAAVAGN---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VRIPVPDPVSPPQLLAP---------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ------------------------------------ITGGTAGTAGAAGN
Rv3512|M.tuberculosis_H37Rv         ------------------------------------ITGGTAGTAGAAGN
MMAR_1594|M.marinum_M               TMGSAGTAGDGGTGGLGGHGGTGADNTTTVSAGAQGATGGTGGAGGQGGT
MUL_4367|M.ulcerans_Agy99           ----------------------------------------AAGFPGGGGT
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TGGIGGAGST
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------TGGIGGAGST
MSMEG_0868|M.smegmatis_MC2_155      -----------------------------------TTIDKGKAAGGNGGD
TH_3810|M.thermoresistible__bu      ----------------------------------------------HGGR
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------AAVAGNAAV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------PRLSVPQPV
                                                                                      

Mb3541|M.bovis_AF2122/97            GGAAGKG-----GAGGQGGTG-----GGTG----------------GQGG
Rv3512|M.tuberculosis_H37Rv         GGAAGKG-----GAGGQGGTG-----GGTG----------------GQGG
MMAR_1594|M.marinum_M               GGAAGTGTGGTQGAGGQGGTGGTGGQGGTGGTGTDSTDPTLVGQAGGQGG
MUL_4367|M.ulcerans_Agy99           TGAWGTG---------------------------------------GAGG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTG---------------------------------------GTGG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTG---------------------------------------GTGG
MSMEG_0868|M.smegmatis_MC2_155      GGFNGTG-----------------------------------------GA
TH_3810|M.thermoresistible__bu      GGFLGIG------------------------------------------G
MAB_4284c|M.abscessus_ATCC_199      GGVLNTG------------------------------------------V
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                QPPVRVP---------------------------------------QPPS
                                                                                      

Mb3541|M.bovis_AF2122/97            AGGDGGAGGTGGDRTVGGGTVPAGSGG----------------------Q
Rv3512|M.tuberculosis_H37Rv         AGGDGGAGGTGGDRTVGGGTVPAGSGG----------------------Q
MMAR_1594|M.marinum_M               TGGTGGAAGQGGTGSVTGAEGSAGDGGSGGLGGHGGTGADNTTAVSAGAQ
MUL_4367|M.ulcerans_Agy99           AGGAGGAGDHGGVGVNPGDSGTAGWAG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTGGTGG--------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTGGTGG--------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TGGRGGDGAGASVWKANGQHSTG--------------------------Q
TH_3810|M.thermoresistible__bu      SGGWGG--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SGAIGGSSHVGG--------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PPQVGGTVPQSP--------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GGNAGGGGAGGQGGAD----------------GGSGGDGGDAGTGGN---
Rv3512|M.tuberculosis_H37Rv         GGNAGGGGAGGQGGAD----------------GGSGGDGGDAGTGGN---
MMAR_1594|M.marinum_M               GATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGTGTD
MUL_4367|M.ulcerans_Agy99           -GAGGAGGAGGSAAFN-----------------GVNGAGGAGGNGGA---
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGTGGKGGTG--------------------GTGGAGGTGGD---
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGTGGKGGTG--------------------GTGGDGGTGGT---
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGGDGGTFVN--------------AGANGNGGAGGAGGVS--
TH_3810|M.thermoresistible__bu      -----HGGNGGDTDAD-------------------GGNGGD---------
MAB_4284c|M.abscessus_ATCC_199      AINESLGGSGSVGGST------------------AVGGGAHTGVG-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PQHQTPPGEGTPPKPD--------------------GPGNYGGGHVP---
                                                                                      

Mb3541|M.bovis_AF2122/97            ----------------GGNGGNRNSG--------------NGTGGAGGNG
Rv3512|M.tuberculosis_H37Rv         ----------------GGNGGNRNSG--------------NGTGGAGGNG
MMAR_1594|M.marinum_M               STDPTLAGQAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGDG
MUL_4367|M.ulcerans_Agy99           ----------------GGGGGAGASG--------------IGAGVAGGDG
Mflv_5091|M.gilvum_PYR-GCK          ----------------GGTGG---------------------TGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       ----------------GGTGG---------------------TGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      ----------------EGEGGTGGHG---------------GDGGRGGDG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ----------------GGGANGGAGGAGGSG-------------------
Rv3512|M.tuberculosis_H37Rv         ----------------GGGANGGAGGAGGSG-------------------
MMAR_1594|M.marinum_M               GTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTGTGGTQGAGGQGGT
MUL_4367|M.ulcerans_Agy99           -------------------GTGGTGGAAGTG-------------------
Mflv_5091|M.gilvum_PYR-GCK          -------------------GTGGTGGTGGAG-------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------GTGGTGGTGGAG-------------------
MSMEG_0868|M.smegmatis_MC2_155      -------------------ALGGNGGTGGVG-------------------
TH_3810|M.thermoresistible__bu      ---------------------GGNGGSAGRG-------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------GGVSTGVGVG-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------TPGAGGSGGSG-------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            -----------------------GGTGGNGGAGGDAGDAGNGGNGNGTGN
Rv3512|M.tuberculosis_H37Rv         -----------------------GGTGGNGGAGGDAGDAGNGGNGNGTGN
MMAR_1594|M.marinum_M               GGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMGA
MUL_4367|M.ulcerans_Agy99           ------------------------GAAGTGGTGGAAGAAGSAGDGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------DGTGGTGGTGGTGGQGGQGGQGGT
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------DGLGGTGGTGGTGGFGGQGGQGGT
MSMEG_0868|M.smegmatis_MC2_155      -----------------------LGNGGKGGNGGNGGNGGTYVDPSHTGA
TH_3810|M.thermoresistible__bu      ------------------------------GTGGLRGVFGINGGNGRAGL
MAB_4284c|M.abscessus_ATCC_199      ---------------------------SHVGGGISESLGGSGSVGGSTAV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------GGHVPTPGAGGSGGSG--GGHVPT
                                                                                      

Mb3541|M.bovis_AF2122/97            GGNGGNGGIAGMGGNGGAG------------------------------T
Rv3512|M.tuberculosis_H37Rv         GGNGGNGGIAGMGGNGGAG------------------------------T
MMAR_1594|M.marinum_M               EGSSGDGGTGGLGGDGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAA
MUL_4367|M.ulcerans_Agy99           GGAGDDGSAGVVSGDPGTAG------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGTGGQGGLGGGGGTGGQG-------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGQGGLGGVGGTGGTG-------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGNGGAGRIRVNNGTATG-----------------------------
TH_3810|M.thermoresistible__bu      GGRGXXX-------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGGAHTGVGGGVSTGVGVG-------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PGTGGPGGTGGSGGGHVPTP------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GSGNGGNGGSGGNG-GNAGMGGNSGTGS----------------GDGGAG
Rv3512|M.tuberculosis_H37Rv         GSGNGGNGGSGGNG-GNAGMGGNSGTGS----------------GDGGAG
MMAR_1594|M.marinum_M               GTGTGGTQGAGGQG-GTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTG
MUL_4367|M.ulcerans_Agy99           --KAGGAGGAGGVG-GNGVAGGVNGSGG--------------------AG
Mflv_5091|M.gilvum_PYR-GCK          --GTGGTGGQGGTG-GTGGTGGTGGTGG--------------------AG
Mvan_1264|M.vanbaalenii_PYR-1       --GTGGTGGQGGTG-GTGGTGGTGGTGG--------------------AG
MSMEG_0868|M.smegmatis_MC2_155      -TATGGNGGNGGNGDADGHRGGKGGDGGE------------ALIRATVIG
TH_3810|M.thermoresistible__bu      --XGGGVGAAVRSG--NGVFSGGGGTPS----------------------
MAB_4284c|M.abscessus_ATCC_199      --SHVGGGISESLG-GSGSVGGSTAVGG---------------------G
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----GAGTPGGSGGGHLPFPGAGSTPG---------------------G
                                                                                      

Mb3541|M.bovis_AF2122/97            GNGGAAGTGGTG------------GDGGLTGTGGTGG-------------
Rv3512|M.tuberculosis_H37Rv         GNGGAAGTGGTG------------GDGGLTGTGGTGG-------------
MMAR_1594|M.marinum_M               GTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGAGGTGGQGTTAVNPGDTGG
MUL_4367|M.ulcerans_Agy99           GAGGAGGTGGAG----------------ASGVPASVD-------------
Mflv_5091|M.gilvum_PYR-GCK          GDGGLGGLGGFG------------------GSGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1       GDGGLGGLGGFG------------------GVGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155      SNASGTATGGDG------------------GNGGTLG-------------
TH_3810|M.thermoresistible__bu      --------AGFG-------------------VPTTIQ-------------
MAB_4284c|M.abscessus_ATCC_199      AHTGVGGGVNTG-----------------VGVGSHVG-------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SGGGHLPTPGAG------------------TPGGGLG-------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------SGGTGGDGGNGGNGGNGADNTANM
Rv3512|M.tuberculosis_H37Rv         --------------------------SGGTGGDGGNGGNG---ADNTANM
MMAR_1594|M.marinum_M               QGASGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGAGGSGGTGGDGTDNS
MUL_4367|M.ulcerans_Agy99           ---------------------------GGDGGAGGAGGAAG---------
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------QGGLGGPGGSTGG--------
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------QGGQGGPGGSTGG--------
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------ATNGTGGAATIVAYNVVQANPQ
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            TAQ--AGGDGGNGGDGGFGGGAG-----AGGGGLTAGANGTGGQGGAGGD
Rv3512|M.tuberculosis_H37Rv         TAQ--AGGDGGNGGDGGFGGGAG-----AGGGGLTAGANGTGGQGGAGGD
MMAR_1594|M.marinum_M               TTPGAAGGAGGQGGTGGTGGAAG-----SGGTGSTMGAEGSSGDGGTGGL
MUL_4367|M.ulcerans_Agy99           -----TGGSGGSAGNTGAGGAGG-----AGGAGGSAASTGVNGDGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          -----AGGAGGQAGTAGKGGLFG-----GSGSAGKAGATGAAG--ASGGK
Mvan_1264|M.vanbaalenii_PYR-1       -----AGGAGGQAGVAGKGGLFG-----GSGSAGTAGVTGASG--ASGGK
MSMEG_0868|M.smegmatis_MC2_155      ASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGID
TH_3810|M.thermoresistible__bu      ----FPAGSCTSRAVSREGIMPS-----SRAASARAGAACASSTSRSRRS
MAB_4284c|M.abscessus_ATCC_199      --GGISESLGGSGSVGGSTAVGG-------GAHTSAINDALGGSGSVGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------GFGGGHAPAPGGGLGG------GGGHAPAPGGGLGGFGGGHSG
                                                                                      

Mb3541|M.bovis_AF2122/97            GGNGAIGGHGPLTDDPG--------------------------------G
Rv3512|M.tuberculosis_H37Rv         GGNGAIGGHGPLTDDPG--------------------------------G
MMAR_1594|M.marinum_M               GGAGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTGTGGIQGAGG
MUL_4367|M.ulcerans_Agy99           GGVGGLGGDSAATAGGG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GAQGATGAQG----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GAQGATGAQG----------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGLGGNGGDGVVNTTAN-------------------------------AA
TH_3810|M.thermoresistible__bu      FCCSRA--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TAVGGGAHTSAINESMN---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGLGGLGGGHK---------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            NGGTGGNGGTGGTGG-----------------------------------
Rv3512|M.tuberculosis_H37Rv         NGGTGGNGGTGGTGG-----------------------------------
MMAR_1594|M.marinum_M               QGGTGGTGGQGGTGGDGAESTDPTLAGQAGGQGGTGGTGGAAGQGGTGSV
MUL_4367|M.ulcerans_Agy99           --GAGGDGGKGGAGG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --ATGAQGATGATGA-----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --ATGAQGATGATGA-----------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NPGSATGTATGGDGGKATG-------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---SSINASHSSSMN-----------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ---------AGIGSLG----------------------------------
Rv3512|M.tuberculosis_H37Rv         ---------AGIGSLG----------------------------------
MMAR_1594|M.marinum_M               AGTDGSAGDGGTGGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGQGGTG
MUL_4367|M.ulcerans_Agy99           ---------AGVNGVG----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------TASQGGNG----------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            -------GGTGGDGGNGGTGGNGGTGGEGGE---------------VGGA
Rv3512|M.tuberculosis_H37Rv         -------GGTGGDGGNG---GNGGTGGEGGE---------------VGGA
MMAR_1594|M.marinum_M               GAAGTGTGGTQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGT
MUL_4367|M.ulcerans_Agy99           ----------GGDGGKGGTGGAGGAGGAGSD----------------GII
Mflv_5091|M.gilvum_PYR-GCK          ------------AGKAGATGAAGAAGAAGSA----------------GTT
Mvan_1264|M.vanbaalenii_PYR-1       ------------SGAQGSAGSAGSAGVAGSA----------------GTT
MSMEG_0868|M.smegmatis_MC2_155      -------GPSWVQSGYGSTLGGNATGTATAG---------------KGGE
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------ESFGSSMGSHGAAGTG------------------F
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            GGTGGAAGNG------------GDGGTGGTGGGD----------------
Rv3512|M.tuberculosis_H37Rv         GGTGGAAGNG------------GDGGTGGTGGGD----------------
MMAR_1594|M.marinum_M               GGTGGAAGQGGTGSTMGSAGTAGDGGTGGLGGGGGTGADNTTAVSAGAQG
MUL_4367|M.ulcerans_Agy99           PSNGGLGGNG------------GNGGNGGQAFGDG---------------
Mflv_5091|M.gilvum_PYR-GCK          GAQGSAGTNG------------ANGANGSQ--------------------
Mvan_1264|M.vanbaalenii_PYR-1       GAQGSAGTNG------------ANGANGSQ--------------------
MSMEG_0868|M.smegmatis_MC2_155      ASNGGVAGNGG------NALVMAAGTTGVATGNTATGGD-----------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      EAQGHAQGHAS---------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ----------------------------GGAGGTGGTGGTGGLGDP----
Rv3512|M.tuberculosis_H37Rv         ----------------------------GGAGGTGGTGGTGGLGDP----
MMAR_1594|M.marinum_M               ATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDS
MUL_4367|M.ulcerans_Agy99           ---------------------------VGGAGGIGGKGGNAAIGTIVIN-
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------GAAGKAGATGTTGATG------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------GAAGKAGATGTTGATG------
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------GGAATTAGATGGAGGFSNIAAIH
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------ETAHTTLPGAEHH--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               TDPTLAGQAGGQGGTGGTGGAAGTGGTGSVTGTDGTAGDGGTGGLGGHGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ---------------RVGGSGGDGGTGGSGGAAGN---------------
Rv3512|M.tuberculosis_H37Rv         ---------------RVGGSGGDGGTGGSGGAAGN---------------
MMAR_1594|M.marinum_M               AGADNTTTVSAGAQGATGGTGGAGGTGGTGGAAGTGTGGTQGAGGQGGTG
MUL_4367|M.ulcerans_Agy99           -----------------GGVGGAGGSGGLGGATED---------------
Mflv_5091|M.gilvum_PYR-GCK          -------------------AAGEDGDAGSGGSGIN---------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------AAGDAGDPGSEAVDIN---------------
MSMEG_0868|M.smegmatis_MC2_155      -----------------GAITDSTAISGHGGAGNG---------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ------------------------------GGNGGNAGAGGN--------
Rv3512|M.tuberculosis_H37Rv         ------------------------------GGNGGNAGAGGN--------
MMAR_1594|M.marinum_M               GTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGSGGTGSVTGTDG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               TAGDGGTGGLGGDGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGT
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ---------GNGGTGGAGGIGG--TGGNGGD--AEPGVPPGAGGAGGAGT
Rv3512|M.tuberculosis_H37Rv         ---------GNGGTGGAGGIGG--TGGNGGD--AEPGVPPGAGGAGGAGT
MMAR_1594|M.marinum_M               GTGGIQGAGGQGGTGGAGGSGG--TGGDGTDNSTTPGAAGGAGGQGGTGG
MUL_4367|M.ulcerans_Agy99           ---------GVGGVGCAGGAGG--NGG-RGDMLFTVGGSGGTGGDGGGGG
Mflv_5091|M.gilvum_PYR-GCK          -----------GGAGGAGGAGG--EGGEGGD--------GGKGGAGAEGG
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGAGGAGGAGG--EGGEGGA--------GGAGGDGSEGG
MSMEG_0868|M.smegmatis_MC2_155      ---------GNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            TGGK-GGTGGNGSGTGSGGTGGDGGTG-----------------------
Rv3512|M.tuberculosis_H37Rv         TGGK-GGTGGNGSGTGSGGTGGDGGTG-----------------------
MMAR_1594|M.marinum_M               TGGA-AGQGGTGSTMGSDGSSGDGGTGGLGGDGGGAGQGTTGTAGAGTGG
MUL_4367|M.ulcerans_Agy99           SASG-SGTGGSGGTGGVGGIGGDGKLG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          AGGG-GGAGGSG-------AGGAGGAG-----------------------
Mvan_1264|M.vanbaalenii_PYR-1       AGGS-GGAGGSG-------TGGAGGAG-----------------------
MSMEG_0868|M.smegmatis_MC2_155      TGGASGGDGGNGGNTSVWKSGGQTADG-----------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            -------------------------GGGGNGGTGWNGGKGDTG-------
Rv3512|M.tuberculosis_H37Rv         -------------------------GGGGNGGTGWNGGKGDTG-------
MMAR_1594|M.marinum_M               QGASGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGTGGTGTDST
MUL_4367|M.ulcerans_Agy99           -------------------------GFGGDGGDGGDGGFGVIGG------
Mflv_5091|M.gilvum_PYR-GCK          -------------------------GSGGSGGSGGSGG------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------GSGGSGGSGGAGG------------
MSMEG_0868|M.smegmatis_MC2_155      -----------------------EHNTGGNGGNGGDGSEPGPGGNG----
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            ----------------SGGGAGDGGK------------------------
Rv3512|M.tuberculosis_H37Rv         ----------------SGGGAGDGGK------------------------
MMAR_1594|M.marinum_M               DPSQIAQAGGQGGTGGTGGAAGQGGTGSTMGAEGSSGDGGTGGLGGHGGA
MUL_4367|M.ulcerans_Agy99           ----------------QGGGGGFGGLG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------SGGAAGDSDD------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------SGGAAGDSD-------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------AGGAGGNGGTG-----------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            -------------APAGGTGGAGGDG--------------GAGGKGGSGG
Rv3512|M.tuberculosis_H37Rv         -------------APAGGTGGAGGDG--------------GAGGKGGSGG
MMAR_1594|M.marinum_M               GADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGG
MUL_4367|M.ulcerans_Agy99           ---------------GTGAGGAPSDK--------------GINGEPGNPG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------GTTAGGSGNGGNGGNG--------------GNGGADGTPG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            V-------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         V-------------------------------------------------
MMAR_1594|M.marinum_M               TGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGSTMGSAGT
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TAGTTGANNP----------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               AGDGGTGGLGGGGGTGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------------------------------------------------
Rv3512|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1594|M.marinum_M               TGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPTLAGQAGGQGGTGETGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3541|M.bovis_AF2122/97            --------
Rv3512|M.tuberculosis_H37Rv         --------
MMAR_1594|M.marinum_M               AGSGGTGS
MUL_4367|M.ulcerans_Agy99           --------
Mflv_5091|M.gilvum_PYR-GCK          --------
Mvan_1264|M.vanbaalenii_PYR-1       --------
MSMEG_0868|M.smegmatis_MC2_155      --------
TH_3810|M.thermoresistible__bu      --------
MAB_4284c|M.abscessus_ATCC_199      --------
MLBr_01183|M.leprae_Br4923          --------
MAV_4827|M.avium_104                --------