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VSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSARIAALFGMYGLEYQAISAQVA AYHQQFVQTLRTGAASYMLAEATNVEQNLLNLINAPTQTLLGRPLIGDGANATTPGGAGGDGGLLFGSGG NGAPGAPGQAGGAGGSAGLLGNGGSGGAGGTGAPGGNGGNAGWLYGRGGVGGAGGIGGGTGGAGGHAWLF GHGGTGGIGGGPGGNGGWLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGGAGGTGGGAGGTGGNAAW LLGGGGTGGAGGIGGGNGGHGGNGGWLLGNGGNGGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGA GSTGTAGGGSGGTGGDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGGAGGAGGNGGAGGQAALLF GRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGGTGGDGGAPGNGGAGGAGQLLSHSGVAGASGKGG AGGTGGNGGAGSAGADAPAGSGAMGSTGFAGGAGGDGGNGGGSGASQGNGGNGGNGGTGGKGGTGGAGMN SLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGG AGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGA GGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNG GNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNG GNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGDGALAGSSG GAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGGNGGIGAAGTTGPVGTGASGGTGGSGGAGGTGGDGGA ANGGTAGAGGAGGNGGKGGDGGAGVTSSTAGNSGGAGGSGGKGGDAGAGGAGATPGANGIAGNGGDGGDG AAGAVGISGATGAGDGGHGGTGGAGGNGGTGGAGGSGIDGVGGGTGGTGGNGGNGAIGGAGGDAGGSGNS GGNGGTGGKGGNAGAGGAAGSNGGTVGANGTGGDGGNGGAAGAATAGSNGGAGTGSAGGNGGTGGRGGSG GAGGDGIGGVGGGKGGNGADGEVGGAGGAGGSGPNTSPGGNGGQGGQGGSGGAGGAAGAGGAGGGANGTA GNGGQGGAGGTGGAGAASSATNGGSGGAGGTGGAGGTGGAGGDGVGGAGGGNGGHGGDAGDGGNGANGNN RSSGSFLAAGGTGGAAGDGGQGGQGGAGGGAGGQGGAGGAGGTGGNGGNITGGTAGTAGAAGNGGAAGKG GAGGQGGTGGGTGGQGGAGGDGGAGGTGGDRTVGGGTVPAGSGGQGGNAGGGGAGGQGGADGGSGGDGGD AGTGGNGGNGGNRNSGNGTGGAGGNGGGGANGGAGGAGGSGGGTGGNGGAGGDAGDAGNGGNGNGTGNGG NGGNGGIAGMGGNGGAGTGSGNGGNGGSGGNGGNAGMGGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLTG TGGTGGSGGTGGDGGNGGNGGNGADNTANMTAQAGGDGGNGGDGGFGGGAGAGGGGLTAGANGTGGQGGA GGDGGNGAIGGHGPLTDDPGGNGGTGGNGGTGGTGGAGIGSLGGGTGGDGGNGGTGGNGGTGGEGGEVGG AGGTGGAAGNGGDGGTGGTGGGDGGAGGTGGTGGTGGLGDPRVGGSGGDGGTGGSGGAAGNGGNGGNAGA GGNGNGGTGGAGGIGGTGGNGGDAEPGVPPGAGGAGGAGTTGGKGGTGGNGSGTGSGGTGGDGGTGGGGG NGGTGWNGGKGDTGSGGGAGDGGKAPAGGTGGAGGDGGAGGKGGSGGV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | - | 100% (1938) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb3538 | PE_PGRS54 | 0.0 | 54.84% (1528) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 0.0 | 48.78% (1470) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 51.18% (803) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3512 | PE_PGRS56 | 0.0 | 76.97% (1094) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 3e-11 | 35.87% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 3e-59 | 31.73% (561) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_1594 | - | 0.0 | 54.41% (2235) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 5e-27 | 44.38% (169) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-180 | 41.47% (1073) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-51 | 45.27% (296) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 49.05% (1162) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 0.0 | 50.19% (805) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb3541|M.bovis_AF2122/97 MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSAR Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M MSYMSISPEIVSSAAGELANIGSTVSAANAAAAVATTELLAAGSDEVSTR MUL_4367|M.ulcerans_Agy99 MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSAA Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -----MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 IAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEAT------N Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M IAALFGANGVEYQAISAQIASFHDRFVAALNTGTSSYVWAEAT------N MUL_4367|M.ulcerans_Agy99 IAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQE Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 LAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 VEQNLLNLINAPTQTLLGRPLIGDGANATTPGGAGGDGGLLFGSGGNGAP Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M VEQNLLNAVNAPVQTLLGRPLIGNGANATTPGGAGGDGGLLYGSGGNGAA MUL_4367|M.ulcerans_Agy99 LEQQALGVVNAPSMALFGRPSIGN-------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GAPGQAGGAGGSAGLLGNGGSGGAGGTG-APGGNGGNAGWLYGRGGVGGA Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GAPGQAGGAGGSAGLWGNGGSGGSGGIGGGTGGNGGSGGWLLGRGGIGGA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 LIPNAPTEPADMPGVWAVMAWAR--------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGIGGGTGGAGGHAWLFGHGGTG--------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGTGGGSGGSGGGAWLFGDGGAGGMGGTGGSGGGFGGTGGHGGLLYGNGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M AGGAGATGQTGGSGGWAALWGRGGAGGAGGDNGGFAGGDGGHGGLLCGAG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ---GIGGGPGGNGGWLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GDGGLGGGDGGNAGWLLGFGGHGGAGGDGGFAGGEGGNGGWLLGFGGHGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AGGTGGGAGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGGWLLGNGGN Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M TGGIGGGTGGAGGAGGLVMGFGGHGGTGGIGGGAGGAGGQAALLFGHGGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGT Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGAGGVGTAGGAGGAGGDGGNPGWLLGRAGSGGDGGAGGAATTVGATGGV MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGG------AGGAG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGHGGAGGRGGVLMGGGAGGDGGAGGAGADGSNGVGDGGNGATGGGGGVG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GNGGAGGQAALLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GDGGAGGQAALLFGCGGTGGHAGAGGAGGGGGTGADS----LTGIGGAGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 TGGDGGAPGNGGAGGAGQLLSHSGVAGASGKGGAGGTGGNGGAGSAGADA Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M DGGIGGASGQAGAGGAGNLFSHNGSRGHAGIGGDGGDGGTGGTGGEGTDA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 PAGSGAMGSTGFAGGAGGDGGNGGGSGA---------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M AAGSGLTGGTGYAGGTGGTGGAGGNSGLGGTNGSGGHGGTGGTGGTGGTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GSGADNTTGIGGDGGQGGTGGDAGAGGAGGNSGFGGTGGTTGTHGDAGIG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ------------------------------------------------SQ Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GDGGDGGTGGTGGQGTDAAAGTGLTGGTGYAGGTGGAGGAGGNSGLGGTN MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GNGGNGGNGGTGGKGGTGGAGMNSLDP----------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GSGGHGGTGGTGGTGGTGGSGADALDGSGASGHDGGDSGAGGDGGTGGAG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GNAGTGAGAAGNNGDGGAGGTGGNSGAQAGDGGAGAANTTIGGTGGAGGS MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGNIGAGGAGGQGGAAGTTSGVGGASGTSGTSGQSIGTGGDGGAGGDGGT MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GTTGADAAAGSGLGGDIGGTGGAGGAGGTGGSGGTDSGVGGSGGVGGVGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ---------------LLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M TGGQGGAGSDNSANAGVAGGAGGQGGAGGTGGAAGSGGTGSVAGADGSSG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 NGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M DGGTGGLGGDGGAGGTGSMGAVDGGTGGQGASGGAGGQGGTGGAAGAGTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAG Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GIQGAGGQGGTGGTGGTGGTGGDGAESTDPSLAGQAGGQGGTGGTGGAAG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGA Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M QGGTGSVTGAEGSAGDGGTGGLGGDGGTGADNTTTVSAGAQGATGGTGGA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQ Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M GGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGAESTDPTLAAQ MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------RQPMYSDPAMRTTVNPQAQ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 DGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTT Rv3512|M.tuberculosis_H37Rv ---------------------PQGADGNAGNGGDGGVGGNGGNGADNTTT MMAR_1594|M.marinum_M AGGQGGTGGTGGAAGQGGTGSTMGAEGSSGDGGTGGLGGDGGAGADNTTT MUL_4367|M.ulcerans_Agy99 -----------------------GVDGVAGTGQAGGAGGILWGNGGNGGL Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP MSMEG_0868|M.smegmatis_MC2_155 LPVPTVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTIS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------MSIIDFILNLFRDPVEAASYVADPEAALANA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEE Mb3541|M.bovis_AF2122/97 AAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGG--NGGNGGTGGKG Rv3512|M.tuberculosis_H37Rv AAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGG--NGGNGGTGGKG MMAR_1594|M.marinum_M VSTGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGG--QGGTGGTGGTG MUL_4367|M.ulcerans_Agy99 GAAGANGGAGGSAGLIGTGGVGGAGGVGAAGMTGGSG--GAG-GGGGWLW Mflv_5091|M.gilvum_PYR-GCK --MVTFGGGATPTPTSLGAAAVDLSGT-SCGLICNGQ--DGTGQNGGILF Mvan_1264|M.vanbaalenii_PYR-1 WYVVSFGGSGAPTPNNLAASLVDLSGT-SCGLICNGQ--DGTGQNGGILF MSMEG_0868|M.smegmatis_MC2_155 GQYLIGNGINGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLF TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNP-IHDLSGNLQNYY MLBr_01183|M.leprae_Br4923 ----------------------------MPLFLNAEP--QALTAAANTLE MAV_4827|M.avium_104 DAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLE Mb3541|M.bovis_AF2122/97 GTGGDG-------ALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG Rv3512|M.tuberculosis_H37Rv GTGGDG-------ALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG MMAR_1594|M.marinum_M GSGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDG MUL_4367|M.ulcerans_Agy99 GAGGSG-----------GAAGAGGSGGSGG--WLWGNAGQTAGAGVGGAG Mflv_5091|M.gilvum_PYR-GCK GNGGSG----------WNSDVVGMDGGNGGNGGLFG--------GNGGNG Mvan_1264|M.vanbaalenii_PYR-1 GNGGSG----------WNSEIAGVSGGNGGNAGLFG--------GNGGNG MSMEG_0868|M.smegmatis_MC2_155 GNGGNG-----------GVGWAGLDGGNGGSGGLLM--------GIGGAG TH_3810|M.thermoresistible__bu ---------------------VDGDGGSGGRTGLFS------KLSRGGDG MAB_4284c|M.abscessus_ATCC_199 AAQPDG------------PSILSPSLLSPRDNDFLSHNDTDFASHNPIAS MLBr_01183|M.leprae_Br4923 GLSAAT---------------VASNAAAAQLTTEIA--------PPAADD MAV_4827|M.avium_104 AAALRD----------------ALAARRIDNVMLVSAFLAAAALAQNVGG . Mb3541|M.bovis_AF2122/97 GKGGNGGIGAAGTTG-----PVGTGASGGTGGSGGAGGTGGDGG--AANG Rv3512|M.tuberculosis_H37Rv GKGGNGGIGAAGTTG-----PVGTGASGGTGGSGGAGGTGGDGG--AANG MMAR_1594|M.marinum_M GTGGLGGDGGEGGQGTTAWNPGDTGGQGASGGAGGTGGTGGAAG--TGTG MUL_4367|M.ulcerans_Agy99 GAGGAGDAGDQGVSG------VAPGEAGAVGFAGGAGGAGGAGG--NGVG Mflv_5091|M.gilvum_PYR-GCK GNGLGGGNGGNG------------GNAGAFALFG-NGGNGGNGG--VGVV Mvan_1264|M.vanbaalenii_PYR-1 GNGLGSGDGGNG------------GDAGLFSLFG-RGGNGGNGG--VGIA MSMEG_0868|M.smegmatis_MC2_155 GAGGVGADGTSAHVDG-----GTGGTGGTGGGTGGTGGIGGTGGGLFGLL TH_3810|M.thermoresistible__bu GDGGLG-------------------------------GNGGHGG------ MAB_4284c|M.abscessus_ATCC_199 GNQVMSPSGNVDSFN-------------RGPLLDLSFGDLQFGNRDTTAI MLBr_01183|M.leprae_Br4923 VSILLAHF------------------------------FSGHGR------ MAV_4827|M.avium_104 AMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLS . Mb3541|M.bovis_AF2122/97 G-TAGAGGAGGNGGKGGDGGAG-------VTSSTAGNSGGAGGSGGKGGD Rv3512|M.tuberculosis_H37Rv G-TAGAGGAGGNGGKGGDGGAG-------VTSSTAGNSGGAGGSGGKGGD MMAR_1594|M.marinum_M G-IQGAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGA MUL_4367|M.ulcerans_Agy99 GGVNGAGGAGGAGGVGGGGGAGASG----VGAGVAGGDGGTGGAGGAAGV Mflv_5091|M.gilvum_PYR-GCK G---ATGAVGAPGVAGATGATG-------VTSGVVGGNGEDAVGYGATGA Mvan_1264|M.vanbaalenii_PYR-1 G---ATGAVGAPGVAGATGATG-------VTSNVTGGNGADAVGYGATGA MSMEG_0868|M.smegmatis_MC2_155 G-HSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGT TH_3810|M.thermoresistible__bu G--TGIISLLSLAGNGGNGGNG---------YRTTDNNALDGGHGGNGGN MAB_4284c|M.abscessus_ATCC_199 G--DGAVAVGGSNSGPIASGQGS-----TAVNGDVRDSNIINADHGSNVG MLBr_01183|M.leprae_Br4923 -------QYQAHASQGATNHQD-------LIQSLLTSSSAYAGTETANHD MAV_4827|M.avium_104 AMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETAL . . Mb3541|M.bovis_AF2122/97 AGAGGAGATPGANGIAGNGGDG---GDGAAGAVGISGATGAGDGGHGGTG Rv3512|M.tuberculosis_H37Rv AGAGGAGATPGANGIAGNGGDG---GDGAAGAVGISGATGAGDGGHGGTG MMAR_1594|M.marinum_M AGTGGTGSTMGAEGSSGDGGSGGLGGDGGAGGQGTTGTAGAGTGGQGASG MUL_4367|M.ulcerans_Agy99 GGAAGTGGTGGAAGVAGTGGDG---GDGGAGGAGSDASLAGQAGFAGGSG Mflv_5091|M.gilvum_PYR-GCK AGAAGAAGAAGAAGAVG--------SAGAAGEAGETGTWGN-AGLPGKAG Mvan_1264|M.vanbaalenii_PYR-1 AGAAGAAGAAGKAGAVG--------SAGTAGSAGAPGVWGN-AGLPGAAG MSMEG_0868|M.smegmatis_MC2_155 GGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTT TH_3810|M.thermoresistible__bu VGFFSLFN------------------------------------------ MAB_4284c|M.abscessus_ATCC_199 VDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRS MLBr_01183|M.leprae_Br4923 SL------------------------------------------------ MAV_4827|M.avium_104 ARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPG Mb3541|M.bovis_AF2122/97 GAGGNGGTGGAGGSGIDGVG--GGTGGTGGNGGNGAIGGAGGD------- Rv3512|M.tuberculosis_H37Rv AAGGNGGTGGAGGSGIDGVG--GGTGGTGGNGGNGAIGGAGGD------- MMAR_1594|M.marinum_M GAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQI MUL_4367|M.ulcerans_Agy99 GAGGVGGSAGAGG-----------VNGSGGDGGAGAAGGAGGA------- Mflv_5091|M.gilvum_PYR-GCK DAGGAGAVG-----------------AAGAAGTVGTAGATGGT------- Mvan_1264|M.vanbaalenii_PYR-1 AAGGAGAIG-----------------TAGVAGAAGTAGATGGT------- MSMEG_0868|M.smegmatis_MC2_155 AAGGNGGTGGTGR---------VIAEGTGSTAEGTATGGDGGHSTG---- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TNIGSGNTTN-------------TEIGSHNQANIGTSTSAGGS------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 DDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSG------- Mb3541|M.bovis_AF2122/97 --AGGSGNSGGNG------------------------------------- Rv3512|M.tuberculosis_H37Rv --AGGSGNSGGNG------------------------------------- MMAR_1594|M.marinum_M AQAGGQGGTGGTGGAAGQGGTGSTIGSAGTAGDGGTGGLGGDGGTGADNT MUL_4367|M.ulcerans_Agy99 -----SATVAGSG------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ------------GTGGKGGNAGAGGAAGS-------------NGGTVGAN Rv3512|M.tuberculosis_H37Rv ------------GIGGKGGNAGAGGAAGS-------------NGGTVGAN MMAR_1594|M.marinum_M TTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQG MUL_4367|M.ulcerans_Agy99 ---------------GVGGDGGAGGAAGG----------------GVGAA Mflv_5091|M.gilvum_PYR-GCK ---------------GTGANGGAG-----------------------GVG Mvan_1264|M.vanbaalenii_PYR-1 ---------------GVGGNGGAG-----------------------QAG MSMEG_0868|M.smegmatis_MC2_155 --------------TGIGGNGGIGSVYAYG------------NNGAVSGT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------A MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GTGGD-------------------GGNGGAAG-------AATAGSNGGAG Rv3512|M.tuberculosis_H37Rv GTGGD-------------------GGNGGAAG-------AATAGSNGGAG MMAR_1594|M.marinum_M GTGGDGADSTDPTLAGQAGGQGGTGGTGGAAGQGGTGSTSGSEGSSGDGG MUL_4367|M.ulcerans_Agy99 SLGGD-------------------GGHAGAGG-------AGGEGLSGGFN Mflv_5091|M.gilvum_PYR-GCK GVGGT--------------------GAAGAAG------GAGGLGETG--- Mvan_1264|M.vanbaalenii_PYR-1 GIGGT--------------------GAAGAAG------QAGTAGETG--- MSMEG_0868|M.smegmatis_MC2_155 ATGGR--------------------GGDGIDG------GTGGAGGMGEIY TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVGGN----------------------------------AGLAGNAG--- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 TG------------------------------------------------ Rv3512|M.tuberculosis_H37Rv TG------------------------------------------------ MMAR_1594|M.marinum_M TGGLGGDGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGTQ MUL_4367|M.ulcerans_Agy99 TG------------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 SG-----------------------------------------------A TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 SAGGNGGTGGRGGSGGAGGD------------------------------ Rv3512|M.tuberculosis_H37Rv SAGGNGGTGGRGGSGGAGGD------------------------------ MMAR_1594|M.marinum_M GAGGQGGTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGQG MUL_4367|M.ulcerans_Agy99 ---AAGGIGGAGGAGGTGGD------------------------------ Mflv_5091|M.gilvum_PYR-GCK ---TTGGAGGVGGQGTAGGT------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 ---VTGGVGGIGGQGTEGGT------------------------------ MSMEG_0868|M.smegmatis_MC2_155 DGEATGISAGGDGGSATGADS----------------------------- TH_3810|M.thermoresistible__bu ----LGGAGGWGGSGVDGVD------------------------------ MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGN------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -LAVVGISAVLALEIALAIG------------------------------ Mb3541|M.bovis_AF2122/97 ---------------GIGGVGG---------------GKGGNGADGEVGG Rv3512|M.tuberculosis_H37Rv ---------------GIGGVGG---------------GKGGNGADGEVGG MMAR_1594|M.marinum_M GTGSTMGSDGSSGDGGTGGLGGDGGEGGQGTTGTAGAGTGGQGASGGAGG MUL_4367|M.ulcerans_Agy99 ----------------SGGVGG----------------VNGDGGAGGGGG Mflv_5091|M.gilvum_PYR-GCK -----------------GGVGG----------------IGGAGSTGAVGG Mvan_1264|M.vanbaalenii_PYR-1 -----------------GGVGG----------------VGGVGATGGAGG MSMEG_0868|M.smegmatis_MC2_155 ----------------LGGRGG---------------TSWVQAGYGPTTG TH_3810|M.thermoresistible__bu ------------------VVGG--------------------NPDGGTPG MAB_4284c|M.abscessus_ATCC_199 -----------------AGLAG------------------NAGLAGNAGL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------IRTTGTVAL Mb3541|M.bovis_AF2122/97 AGGAG-----------GSGPNTSPGGNGGQG------------------- Rv3512|M.tuberculosis_H37Rv AGGAG-----------GSGPNTSPGGNGGQG------------------- MMAR_1594|M.marinum_M TGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGDGADSTDPTLAGQAG MUL_4367|M.ulcerans_Agy99 RGGDG-------------GSSTSTSGVGGAG------------------- Mflv_5091|M.gilvum_PYR-GCK VGGKG-----------IQGGQGLQGGKGGDG------------------- Mvan_1264|M.vanbaalenii_PYR-1 VGGKG-----------IQGGQGLQGGQGGDG------------------- MSMEG_0868|M.smegmatis_MC2_155 GKASG-------------TAKAGHGGKASDG------------------- TH_3810|M.thermoresistible__bu AHGES-------------HTPGVYTDRQGED------------------- MAB_4284c|M.abscessus_ATCC_199 AGNAG------------LAGNAGLAGNAGLA------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 QPTPN-------------QHLIVPTEQAPAP------------------- Mb3541|M.bovis_AF2122/97 GQGGSGGAGGAAGAGGAG--GGANGTAGNGGQGGAGGTGGAGAASSATN- Rv3512|M.tuberculosis_H37Rv GQGGSGGAGGAAGAGGAG--GGANGTAGNGGQGGAGGTGGAGAASSATN- MMAR_1594|M.marinum_M GQGGTGGTGGAAGQGGTGSVAGTDGSSGDGGTGGLGGHGGAGADNTTTVS MUL_4367|M.ulcerans_Agy99 ---GAGGNGGNAGFGVSA-----------GGTGGSAGDGGAG-------- Mflv_5091|M.gilvum_PYR-GCK ---GAGGKGGDADSMGSA-----------GATGGKGGNGGNG-------- Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGDATSMGEA-----------GATGGKGGNGGNG-------- MSMEG_0868|M.smegmatis_MC2_155 ---GKGGNGGDALVMAAG------ATGVATGNTAIGGNGGAAS------- TH_3810|M.thermoresistible__bu ---GEDGTG--------------------TGIGGRGGNGGSS-------- MAB_4284c|M.abscessus_ATCC_199 ---GNAGLAGNAGLAGNAG---------LAGNAGLAGNAGLAG------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --PPVQASAPQPKISVPEP---------VAAPKPLSPPVAAPLPAAPPP- Mb3541|M.bovis_AF2122/97 ----GGSGGAGGTGGAGGTGGAGGDGVGGAG------------------- Rv3512|M.tuberculosis_H37Rv ----GGSGGAGGTGGDGGSGGAGG--TGG--------------------- MMAR_1594|M.marinum_M AGAQGATGGTGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGG MUL_4367|M.ulcerans_Agy99 ----GGAGGVDGVGGASGNGGAAG-------------------------- Mflv_5091|M.gilvum_PYR-GCK -----GRGGLFGKGGNAGNGADGG-------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -----GRGSLFGRGGNAGNGGNGG-------------------------- MSMEG_0868|M.smegmatis_MC2_155 -----ANGAVGGNGGFTNIAAIHG-------------------------- TH_3810|M.thermoresistible__bu ----------SGTHPMAEDG------------------------------ MAB_4284c|M.abscessus_ATCC_199 ------NAGLAGNAGLAGNAGLAG-------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----AAPPLPEAPPIPAAPPVVP-------------------------- Mb3541|M.bovis_AF2122/97 ---------------GGNGGHGGDAGDGGNGANGNNRSSGSFLAAGGTGG Rv3512|M.tuberculosis_H37Rv --------------------------------------------AGGTGG MMAR_1594|M.marinum_M DGTDNSTTPGAAGGAGGQGGTGGTGGAAGQGGTGSTSGSAGSSGDGGTGG MUL_4367|M.ulcerans_Agy99 -----------------------------------------------AGG Mflv_5091|M.gilvum_PYR-GCK -----------------------------------------------TGG Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------------------TGG MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------------SITDS TH_3810|M.thermoresistible__bu -----------------------------------------------EHV MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------------NAGL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------------------------------------VPVV Mb3541|M.bovis_AF2122/97 AAGDGGQGGQ----------------GGAGG----------------GAG Rv3512|M.tuberculosis_H37Rv AAGDGGQGGQ----------------GGAGG----------------GAG MMAR_1594|M.marinum_M LGGDGGEGGQGTTGTAGAGTGGQGASGGAGGQGGTGGAAGTGTGGTQGAG MUL_4367|M.ulcerans_Agy99 AGGSG-----------------------------------------IGAG Mflv_5091|M.gilvum_PYR-GCK AGGAG------------------------------------------GTG Mvan_1264|M.vanbaalenii_PYR-1 NGGNG------------------------------------------GTG MSMEG_0868|M.smegmatis_MC2_155 SATSG-----------------------------------------HGGA TH_3810|M.thermoresistible__bu KALDG------------------------------------------RPG MAB_4284c|M.abscessus_ATCC_199 AGNAG----------------------------------------LAGNA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VPPVP-----------------------------------------VPVP Mb3541|M.bovis_AF2122/97 GQGGAGGAGGTGGNGGN--------------------------------- Rv3512|M.tuberculosis_H37Rv GQGGAGGAGGTGGNGGN--------------------------------- MMAR_1594|M.marinum_M GQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGS MUL_4367|M.ulcerans_Agy99 IDGGAGGAGGTGG------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GTGGAGGTGGTGG------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GTGGNGGTGGTGG------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AQGGNGGNGGNGWVQAYDPNGPAG-------------------------- TH_3810|M.thermoresistible__bu LDGGNGSHGGNGG------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAAVAGNAAVAGN--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VRIPVPDPVSPPQLLAP--------------------------------- Mb3541|M.bovis_AF2122/97 ------------------------------------ITGGTAGTAGAAGN Rv3512|M.tuberculosis_H37Rv ------------------------------------ITGGTAGTAGAAGN MMAR_1594|M.marinum_M TMGSAGTAGDGGTGGLGGHGGTGADNTTTVSAGAQGATGGTGGAGGQGGT MUL_4367|M.ulcerans_Agy99 ----------------------------------------AAGFPGGGGT Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TGGIGGAGST Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------TGGIGGAGST MSMEG_0868|M.smegmatis_MC2_155 -----------------------------------TTIDKGKAAGGNGGD TH_3810|M.thermoresistible__bu ----------------------------------------------HGGR MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------AAVAGNAAV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------PRLSVPQPV Mb3541|M.bovis_AF2122/97 GGAAGKG-----GAGGQGGTG-----GGTG----------------GQGG Rv3512|M.tuberculosis_H37Rv GGAAGKG-----GAGGQGGTG-----GGTG----------------GQGG MMAR_1594|M.marinum_M GGAAGTGTGGTQGAGGQGGTGGTGGQGGTGGTGTDSTDPTLVGQAGGQGG MUL_4367|M.ulcerans_Agy99 TGAWGTG---------------------------------------GAGG Mflv_5091|M.gilvum_PYR-GCK GGTGGTG---------------------------------------GTGG Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTG---------------------------------------GTGG MSMEG_0868|M.smegmatis_MC2_155 GGFNGTG-----------------------------------------GA TH_3810|M.thermoresistible__bu GGFLGIG------------------------------------------G MAB_4284c|M.abscessus_ATCC_199 GGVLNTG------------------------------------------V MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 QPPVRVP---------------------------------------QPPS Mb3541|M.bovis_AF2122/97 AGGDGGAGGTGGDRTVGGGTVPAGSGG----------------------Q Rv3512|M.tuberculosis_H37Rv AGGDGGAGGTGGDRTVGGGTVPAGSGG----------------------Q MMAR_1594|M.marinum_M TGGTGGAAGQGGTGSVTGAEGSAGDGGSGGLGGHGGTGADNTTAVSAGAQ MUL_4367|M.ulcerans_Agy99 AGGAGGAGDHGGVGVNPGDSGTAGWAG----------------------- Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGTGG-------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGTGG-------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TGGRGGDGAGASVWKANGQHSTG--------------------------Q TH_3810|M.thermoresistible__bu SGGWGG-------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SGAIGGSSHVGG-------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PPQVGGTVPQSP-------------------------------------- Mb3541|M.bovis_AF2122/97 GGNAGGGGAGGQGGAD----------------GGSGGDGGDAGTGGN--- Rv3512|M.tuberculosis_H37Rv GGNAGGGGAGGQGGAD----------------GGSGGDGGDAGTGGN--- MMAR_1594|M.marinum_M GATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGQGGTGGTGTD MUL_4367|M.ulcerans_Agy99 -GAGGAGGAGGSAAFN-----------------GVNGAGGAGGNGGA--- Mflv_5091|M.gilvum_PYR-GCK --TGGTGGTGGKGGTG--------------------GTGGAGGTGGD--- Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGTGGKGGTG--------------------GTGGDGGTGGT--- MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVN--------------AGANGNGGAGGAGGVS-- TH_3810|M.thermoresistible__bu -----HGGNGGDTDAD-------------------GGNGGD--------- MAB_4284c|M.abscessus_ATCC_199 AINESLGGSGSVGGST------------------AVGGGAHTGVG----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PQHQTPPGEGTPPKPD--------------------GPGNYGGGHVP--- Mb3541|M.bovis_AF2122/97 ----------------GGNGGNRNSG--------------NGTGGAGGNG Rv3512|M.tuberculosis_H37Rv ----------------GGNGGNRNSG--------------NGTGGAGGNG MMAR_1594|M.marinum_M STDPTLAGQAGGQGGTGGTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGDG MUL_4367|M.ulcerans_Agy99 ----------------GGGGGAGASG--------------IGAGVAGGDG Mflv_5091|M.gilvum_PYR-GCK ----------------GGTGG---------------------TGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 ----------------GGTGG---------------------TGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 ----------------EGEGGTGGHG---------------GDGGRGGDG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ----------------GGGANGGAGGAGGSG------------------- Rv3512|M.tuberculosis_H37Rv ----------------GGGANGGAGGAGGSG------------------- MMAR_1594|M.marinum_M GTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTGTGGTQGAGGQGGT MUL_4367|M.ulcerans_Agy99 -------------------GTGGTGGAAGTG------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------GTGGTGGTGGAG------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------GTGGTGGTGGAG------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------ALGGNGGTGGVG------------------- TH_3810|M.thermoresistible__bu ---------------------GGNGGSAGRG------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------GGVSTGVGVG------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------TPGAGGSGGSG------------------- Mb3541|M.bovis_AF2122/97 -----------------------GGTGGNGGAGGDAGDAGNGGNGNGTGN Rv3512|M.tuberculosis_H37Rv -----------------------GGTGGNGGAGGDAGDAGNGGNGNGTGN MMAR_1594|M.marinum_M GGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTGGTGGAAGSGGTGSTMGA MUL_4367|M.ulcerans_Agy99 ------------------------GAAGTGGTGGAAGAAGSAGDGGAGGA Mflv_5091|M.gilvum_PYR-GCK --------------------------DGTGGTGGTGGTGGQGGQGGQGGT Mvan_1264|M.vanbaalenii_PYR-1 --------------------------DGLGGTGGTGGTGGFGGQGGQGGT MSMEG_0868|M.smegmatis_MC2_155 -----------------------LGNGGKGGNGGNGGNGGTYVDPSHTGA TH_3810|M.thermoresistible__bu ------------------------------GTGGLRGVFGINGGNGRAGL MAB_4284c|M.abscessus_ATCC_199 ---------------------------SHVGGGISESLGGSGSVGGSTAV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------GGHVPTPGAGGSGGSG--GGHVPT Mb3541|M.bovis_AF2122/97 GGNGGNGGIAGMGGNGGAG------------------------------T Rv3512|M.tuberculosis_H37Rv GGNGGNGGIAGMGGNGGAG------------------------------T MMAR_1594|M.marinum_M EGSSGDGGTGGLGGDGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAA MUL_4367|M.ulcerans_Agy99 GGAGDDGSAGVVSGDPGTAG------------------------------ Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGGGGTGGQG------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGLGGVGGTGGTG------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGAGRIRVNNGTATG----------------------------- TH_3810|M.thermoresistible__bu GGRGXXX------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGGAHTGVGGGVSTGVGVG------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PGTGGPGGTGGSGGGHVPTP------------------------------ Mb3541|M.bovis_AF2122/97 GSGNGGNGGSGGNG-GNAGMGGNSGTGS----------------GDGGAG Rv3512|M.tuberculosis_H37Rv GSGNGGNGGSGGNG-GNAGMGGNSGTGS----------------GDGGAG MMAR_1594|M.marinum_M GTGTGGTQGAGGQG-GTGGTGGQGGTGGDGTDNSTTPGAAGGAGGQGGTG MUL_4367|M.ulcerans_Agy99 --KAGGAGGAGGVG-GNGVAGGVNGSGG--------------------AG Mflv_5091|M.gilvum_PYR-GCK --GTGGTGGQGGTG-GTGGTGGTGGTGG--------------------AG Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGQGGTG-GTGGTGGTGGTGG--------------------AG MSMEG_0868|M.smegmatis_MC2_155 -TATGGNGGNGGNGDADGHRGGKGGDGGE------------ALIRATVIG TH_3810|M.thermoresistible__bu --XGGGVGAAVRSG--NGVFSGGGGTPS---------------------- MAB_4284c|M.abscessus_ATCC_199 --SHVGGGISESLG-GSGSVGGSTAVGG---------------------G MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----GAGTPGGSGGGHLPFPGAGSTPG---------------------G Mb3541|M.bovis_AF2122/97 GNGGAAGTGGTG------------GDGGLTGTGGTGG------------- Rv3512|M.tuberculosis_H37Rv GNGGAAGTGGTG------------GDGGLTGTGGTGG------------- MMAR_1594|M.marinum_M GTGGAAGSGGTGSTMGAEGSSGDGGTGGLGGAGGTGGQGTTAVNPGDTGG MUL_4367|M.ulcerans_Agy99 GAGGAGGTGGAG----------------ASGVPASVD------------- Mflv_5091|M.gilvum_PYR-GCK GDGGLGGLGGFG------------------GSGGTGG------------- Mvan_1264|M.vanbaalenii_PYR-1 GDGGLGGLGGFG------------------GVGGTGG------------- MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDG------------------GNGGTLG------------- TH_3810|M.thermoresistible__bu --------AGFG-------------------VPTTIQ------------- MAB_4284c|M.abscessus_ATCC_199 AHTGVGGGVNTG-----------------VGVGSHVG------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SGGGHLPTPGAG------------------TPGGGLG------------- Mb3541|M.bovis_AF2122/97 --------------------------SGGTGGDGGNGGNGGNGADNTANM Rv3512|M.tuberculosis_H37Rv --------------------------SGGTGGDGGNGGNG---ADNTANM MMAR_1594|M.marinum_M QGASGGAGGTGGTGGAAGTGTGGIQGAGGQGGTGGAGGSGGTGGDGTDNS MUL_4367|M.ulcerans_Agy99 ---------------------------GGDGGAGGAGGAAG--------- Mflv_5091|M.gilvum_PYR-GCK -----------------------------QGGLGGPGGSTGG-------- Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------QGGQGGPGGSTGG-------- MSMEG_0868|M.smegmatis_MC2_155 ----------------------------ATNGTGGAATIVAYNVVQANPQ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 TAQ--AGGDGGNGGDGGFGGGAG-----AGGGGLTAGANGTGGQGGAGGD Rv3512|M.tuberculosis_H37Rv TAQ--AGGDGGNGGDGGFGGGAG-----AGGGGLTAGANGTGGQGGAGGD MMAR_1594|M.marinum_M TTPGAAGGAGGQGGTGGTGGAAG-----SGGTGSTMGAEGSSGDGGTGGL MUL_4367|M.ulcerans_Agy99 -----TGGSGGSAGNTGAGGAGG-----AGGAGGSAASTGVNGDGGAGGA Mflv_5091|M.gilvum_PYR-GCK -----AGGAGGQAGTAGKGGLFG-----GSGSAGKAGATGAAG--ASGGK Mvan_1264|M.vanbaalenii_PYR-1 -----AGGAGGQAGVAGKGGLFG-----GSGSAGTAGVTGASG--ASGGK MSMEG_0868|M.smegmatis_MC2_155 ASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGID TH_3810|M.thermoresistible__bu ----FPAGSCTSRAVSREGIMPS-----SRAASARAGAACASSTSRSRRS MAB_4284c|M.abscessus_ATCC_199 --GGISESLGGSGSVGGSTAVGG-------GAHTSAINDALGGSGSVGGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------GFGGGHAPAPGGGLGG------GGGHAPAPGGGLGGFGGGHSG Mb3541|M.bovis_AF2122/97 GGNGAIGGHGPLTDDPG--------------------------------G Rv3512|M.tuberculosis_H37Rv GGNGAIGGHGPLTDDPG--------------------------------G MMAR_1594|M.marinum_M GGAGGTGGQGTTAVNPGDTGGQGASGGAGGTGGTGGAAGTGTGGIQGAGG MUL_4367|M.ulcerans_Agy99 GGVGGLGGDSAATAGGG--------------------------------- Mflv_5091|M.gilvum_PYR-GCK GAQGATGAQG---------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GAQGATGAQG---------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGLGGNGGDGVVNTTAN-------------------------------AA TH_3810|M.thermoresistible__bu FCCSRA-------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTSAINESMN--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GGLGGLGGGHK--------------------------------------- Mb3541|M.bovis_AF2122/97 NGGTGGNGGTGGTGG----------------------------------- Rv3512|M.tuberculosis_H37Rv NGGTGGNGGTGGTGG----------------------------------- MMAR_1594|M.marinum_M QGGTGGTGGQGGTGGDGAESTDPTLAGQAGGQGGTGGTGGAAGQGGTGSV MUL_4367|M.ulcerans_Agy99 --GAGGDGGKGGAGG----------------------------------- Mflv_5091|M.gilvum_PYR-GCK --ATGAQGATGATGA----------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 --ATGAQGATGATGA----------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NPGSATGTATGGDGGKATG------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---SSINASHSSSMN----------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ---------AGIGSLG---------------------------------- Rv3512|M.tuberculosis_H37Rv ---------AGIGSLG---------------------------------- MMAR_1594|M.marinum_M AGTDGSAGDGGTGGLGGHGGAGADNTTTVSAGAQGATGGTGGAGGQGGTG MUL_4367|M.ulcerans_Agy99 ---------AGVNGVG---------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 --------TASQGGNG---------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------GGTGGDGGNGGTGGNGGTGGEGGE---------------VGGA Rv3512|M.tuberculosis_H37Rv -------GGTGGDGGNG---GNGGTGGEGGE---------------VGGA MMAR_1594|M.marinum_M GAAGTGTGGTQGAGGQGGTGGTGGTGGIGGTGTDSTDPSQIAQAGGQGGT MUL_4367|M.ulcerans_Agy99 ----------GGDGGKGGTGGAGGAGGAGSD----------------GII Mflv_5091|M.gilvum_PYR-GCK ------------AGKAGATGAAGAAGAAGSA----------------GTT Mvan_1264|M.vanbaalenii_PYR-1 ------------SGAQGSAGSAGSAGVAGSA----------------GTT MSMEG_0868|M.smegmatis_MC2_155 -------GPSWVQSGYGSTLGGNATGTATAG---------------KGGE TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------ESFGSSMGSHGAAGTG------------------F MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGTGGAAGNG------------GDGGTGGTGGGD---------------- Rv3512|M.tuberculosis_H37Rv GGTGGAAGNG------------GDGGTGGTGGGD---------------- MMAR_1594|M.marinum_M GGTGGAAGQGGTGSTMGSAGTAGDGGTGGLGGGGGTGADNTTAVSAGAQG MUL_4367|M.ulcerans_Agy99 PSNGGLGGNG------------GNGGNGGQAFGDG--------------- Mflv_5091|M.gilvum_PYR-GCK GAQGSAGTNG------------ANGANGSQ-------------------- Mvan_1264|M.vanbaalenii_PYR-1 GAQGSAGTNG------------ANGANGSQ-------------------- MSMEG_0868|M.smegmatis_MC2_155 ASNGGVAGNGG------NALVMAAGTTGVATGNTATGGD----------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EAQGHAQGHAS--------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ----------------------------GGAGGTGGTGGTGGLGDP---- Rv3512|M.tuberculosis_H37Rv ----------------------------GGAGGTGGTGGTGGLGDP---- MMAR_1594|M.marinum_M ATGGTGGAGGQGGTGGAAGTGTGGIQGAGGQGGTGGTGGTGGIGGTGTDS MUL_4367|M.ulcerans_Agy99 ---------------------------VGGAGGIGGKGGNAAIGTIVIN- Mflv_5091|M.gilvum_PYR-GCK ----------------------------GAAGKAGATGTTGATG------ Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------GAAGKAGATGTTGATG------ MSMEG_0868|M.smegmatis_MC2_155 ---------------------------GGAATTAGATGGAGGFSNIAAIH TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------ETAHTTLPGAEHH-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M TDPTLAGQAGGQGGTGGTGGAAGTGGTGSVTGTDGTAGDGGTGGLGGHGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ---------------RVGGSGGDGGTGGSGGAAGN--------------- Rv3512|M.tuberculosis_H37Rv ---------------RVGGSGGDGGTGGSGGAAGN--------------- MMAR_1594|M.marinum_M AGADNTTTVSAGAQGATGGTGGAGGTGGTGGAAGTGTGGTQGAGGQGGTG MUL_4367|M.ulcerans_Agy99 -----------------GGVGGAGGSGGLGGATED--------------- Mflv_5091|M.gilvum_PYR-GCK -------------------AAGEDGDAGSGGSGIN--------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------AAGDAGDPGSEAVDIN--------------- MSMEG_0868|M.smegmatis_MC2_155 -----------------GAITDSTAISGHGGAGNG--------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ------------------------------GGNGGNAGAGGN-------- Rv3512|M.tuberculosis_H37Rv ------------------------------GGNGGNAGAGGN-------- MMAR_1594|M.marinum_M GTGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGSGGTGSVTGTDG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M TAGDGGTGGLGGDGGAGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGT MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ---------GNGGTGGAGGIGG--TGGNGGD--AEPGVPPGAGGAGGAGT Rv3512|M.tuberculosis_H37Rv ---------GNGGTGGAGGIGG--TGGNGGD--AEPGVPPGAGGAGGAGT MMAR_1594|M.marinum_M GTGGIQGAGGQGGTGGAGGSGG--TGGDGTDNSTTPGAAGGAGGQGGTGG MUL_4367|M.ulcerans_Agy99 ---------GVGGVGCAGGAGG--NGG-RGDMLFTVGGSGGTGGDGGGGG Mflv_5091|M.gilvum_PYR-GCK -----------GGAGGAGGAGG--EGGEGGD--------GGKGGAGAEGG Mvan_1264|M.vanbaalenii_PYR-1 -----------GGAGGAGGAGG--EGGEGGA--------GGAGGDGSEGG MSMEG_0868|M.smegmatis_MC2_155 ---------GNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 TGGK-GGTGGNGSGTGSGGTGGDGGTG----------------------- Rv3512|M.tuberculosis_H37Rv TGGK-GGTGGNGSGTGSGGTGGDGGTG----------------------- MMAR_1594|M.marinum_M TGGA-AGQGGTGSTMGSDGSSGDGGTGGLGGDGGGAGQGTTGTAGAGTGG MUL_4367|M.ulcerans_Agy99 SASG-SGTGGSGGTGGVGGIGGDGKLG----------------------- Mflv_5091|M.gilvum_PYR-GCK AGGG-GGAGGSG-------AGGAGGAG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 AGGS-GGAGGSG-------TGGAGGAG----------------------- MSMEG_0868|M.smegmatis_MC2_155 TGGASGGDGGNGGNTSVWKSGGQTADG----------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------GGGGNGGTGWNGGKGDTG------- Rv3512|M.tuberculosis_H37Rv -------------------------GGGGNGGTGWNGGKGDTG------- MMAR_1594|M.marinum_M QGASGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGGTGGTGGTGGTGTDST MUL_4367|M.ulcerans_Agy99 -------------------------GFGGDGGDGGDGGFGVIGG------ Mflv_5091|M.gilvum_PYR-GCK -------------------------GSGGSGGSGGSGG------------ Mvan_1264|M.vanbaalenii_PYR-1 -------------------------GSGGSGGSGGAGG------------ MSMEG_0868|M.smegmatis_MC2_155 -----------------------EHNTGGNGGNGGDGSEPGPGGNG---- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 ----------------SGGGAGDGGK------------------------ Rv3512|M.tuberculosis_H37Rv ----------------SGGGAGDGGK------------------------ MMAR_1594|M.marinum_M DPSQIAQAGGQGGTGGTGGAAGQGGTGSTMGAEGSSGDGGTGGLGGHGGA MUL_4367|M.ulcerans_Agy99 ----------------QGGGGGFGGLG----------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------SGGAAGDSDD------------------------ Mvan_1264|M.vanbaalenii_PYR-1 ----------------SGGAAGDSD------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------------AGGAGGNGGTG----------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------APAGGTGGAGGDG--------------GAGGKGGSGG Rv3512|M.tuberculosis_H37Rv -------------APAGGTGGAGGDG--------------GAGGKGGSGG MMAR_1594|M.marinum_M GADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTGTGGTQGAGGQGGTGG MUL_4367|M.ulcerans_Agy99 ---------------GTGAGGAPSDK--------------GINGEPGNPG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------GTTAGGSGNGGNGGNG--------------GNGGADGTPG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 V------------------------------------------------- Rv3512|M.tuberculosis_H37Rv V------------------------------------------------- MMAR_1594|M.marinum_M TGGTGGIGGTGTDSTDPSQIAQAGGQGGTGGTGGAAGQGGTGSTMGSAGT MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TAGTTGANNP---------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M AGDGGTGGLGGGGGTGADNTTTVSAGAQGATGGTGGAGGQGGTGGAAGTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------------------------------- Rv3512|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1594|M.marinum_M TGGIQGAGGQGGTGGTGGTGGIGGTGTDSTDPTLAGQAGGQGGTGETGGA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------- Rv3512|M.tuberculosis_H37Rv -------- MMAR_1594|M.marinum_M AGSGGTGS MUL_4367|M.ulcerans_Agy99 -------- Mflv_5091|M.gilvum_PYR-GCK -------- Mvan_1264|M.vanbaalenii_PYR-1 -------- MSMEG_0868|M.smegmatis_MC2_155 -------- TH_3810|M.thermoresistible__bu -------- MAB_4284c|M.abscessus_ATCC_199 -------- MLBr_01183|M.leprae_Br4923 -------- MAV_4827|M.avium_104 --------