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M. gilvum PYR-GCK Mflv_3081 (solA)

annotation: N-methyltryptophan oxidase
coordinates: 3261098 - 3262234
length: 378

MTYDVIVIGLGGMGSAAAYHLAARGQRVLGLEKFTPAHDRGSSHGGSRIIRQSYFEDPAYVPLLLRAYEL
WAGLAADSGRDVYRMTGGLFLGPPDCLTVAGSLRASREWGLPHDLLDGKEVRARFPNFTPHPGDVGLYEA
NAGFARPELTVRAHLDLAEKAGATLRFGADVLDWSESSGGVTVRTPGETFTAGQLVICPGAWAPQLLAEF
GIPITVERQVLYWLDPVGGTASFVDHPIFIDENASGAQIYGFPAIDGPRGGVKVAFFRKGVECTPETIDR
TVHDHEVREMRDRVAELLPALDGPCVHSATCMYANTPDQHFVIARHPDSERVTVACGFSGHGFKFVPVVG
EILADLAISGATAHPISLFDPRRLVTTR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3081solA-100% (378)N-methyltryptophan oxidase
M. gilvum PYR-GCKMflv_1296-2e-2228.72% (383) FAD dependent oxidoreductase
M. gilvum PYR-GCKMflv_0955-5e-0724.91% (281) D-amino-acid dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4421solA1e-17175.67% (374) dehydrogenase
M. avium 104MAV_0142-3e-0726.17% (363) FAD dependent oxidoreductase, putative
M. smegmatis MC2 155MSMEG_6264-8e-2328.57% (378) putative oxidoreductase
M. thermoresistible (build 8)TH_2138-4e-0725.77% (291) D-amino-acid dehydrogenase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5513-4e-2129.07% (375) FAD dependent oxidoreductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3081|M.gilvum_PYR-GCK          -----------MTYDVIVIGLGGMGSAAAYHLAARGQRVLGLEKFTPAHD
MMAR_4421|M.marinum_M               --------MATTGYDVIVIGLGGMGSAAAYHLAARGRRVLGLERHQPAHD
MSMEG_6264|M.smegmatis_MC2_155      ---------MSITADVVIVGGGLEGTAAAWALSQRGVTDVVVAERNTVG-
Mvan_5513|M.vanbaalenii_PYR-1       ---------MTETADVVIVGGGLEGAAAAWALSRRGVTDVVVAERNTVG-
MAV_0142|M.avium_104                --------------MIVVIGAGVCGLAAAHELSRRGHDDVVVLEKGQPF-
TH_2138|M.thermoresistible__bu      MSQRFAERVDGGPRSAIVIGAGIVGLSTAWFLQERGVDVCVVDRTGVAAG
                                                    :::* *  * ::*  *  **     : .      

Mflv_3081|M.gilvum_PYR-GCK          RGSSHGGSR----------------IIRQSYFEDPAYVPLLLRAYELWAG
MMAR_4421|M.marinum_M               KGSSHGGSR----------------IIRQSYFEDPGYVPLLLRSYELWER
MSMEG_6264|M.smegmatis_MC2_155      -SGMTGKSS----------------GIVRCHYGVSSLAAMAAVGLDVFEK
Mvan_5513|M.vanbaalenii_PYR-1       -SGMTGKSS----------------GIVRCHYGVSSLAAMAADGLEVFEN
MAV_0142|M.avium_104                -GEQSAGLA----------------RIFRIAHQREALCRLAFAARAGWQR
TH_2138|M.thermoresistible__bu      ASWGNAGWISPGLAIPLNEPGVLRYGLRNLLSPTAPLHLPLTRDLRQWAF
                                     .   .                    : .                  :  

Mflv_3081|M.gilvum_PYR-GCK          LAADSGRDV-YRMTGGLF---------------------LGPPDCLTVAG
MMAR_4421|M.marinum_M               LAIDAQSDI-YRLTGGLF---------------------IGPPDCATVAG
MSMEG_6264|M.smegmatis_MC2_155      AEEIFGDDIGFRQTGYVVG--------------------VGEQNVDALRK
Mvan_5513|M.vanbaalenii_PYR-1       GEDIFGTDIGFRQTGYVVG--------------------VGEQNVESLRK
MAV_0142|M.avium_104                WEAEFGVGRLLGSEGFIA-------------------------AGAAADG
TH_2138|M.thermoresistible__bu      LTRFAANCRRSSWTRALLANKPLNDEAIEAYDVLTANGVDAPVTDAPITA
                                                    :                             .   

Mflv_3081|M.gilvum_PYR-GCK          SLRASREWG---------------LPHDLLDGKEVRARFPNFTPHPGDVG
MMAR_4421|M.marinum_M               SLRASREWD---------------LPHEVLDAPQIAARFPNFTPQPTDIA
MSMEG_6264|M.smegmatis_MC2_155      SLAAQRQVG---------------VQTEEIDASEVAKLWPWADLEPFAAF
Mvan_5513|M.vanbaalenii_PYR-1       SLAAQRAVG---------------VDTEEIDKDEVAKLWPFADLTPFAAF
MAV_0142|M.avium_104                VAQAMKRAG---------------AAFSRLDRDGIAERIPFAD-VPWETG
TH_2138|M.thermoresistible__bu      VFRDPREAGRLRDELRRVAETGRDVEVTELSGADLRERVPLAS-AEITVG
                                         :  .                    :.   :    *          

Mflv_3081|M.gilvum_PYR-GCK          LYEANAGFARPELTVRAHLDLAEKAGATLRFGADVLDWSESSGGVT--VR
MMAR_4421|M.marinum_M               LYEAKAGLARPELTVRAHLELAKRSGATLQFEEPVLNWTTTASGVR--VT
MSMEG_6264|M.smegmatis_MC2_155      GWEARGGYGDAYQTAQAFAIAARAAGVRIRQGATVTELLMGADRVTGVRL
Mvan_5513|M.vanbaalenii_PYR-1       GWEARGGYGDAYQTAQAFSTAARAAGARVRQGTAVTDLLVDGDRVTGVRT
MAV_0142|M.avium_104                IFDPLGG---SLRIRRALTALARR--VVIRCGEVVS---VADDGRT--VL
TH_2138|M.thermoresistible__bu      LEIHGQRYVDPARFVQALADSVVDRGATIHR-MDITGVDSGPGGVT-VHS
                                              .    :*    .    . ::    :       .       

Mflv_3081|M.gilvum_PYR-GCK          TPGETFTAGQLVICPGAWAPQLLAEFG--IPITVERQVLYWLDP---VGG
MMAR_4421|M.marinum_M               TGRDTYTAEQLVVCPGAWAPELLSQLG--IPITVQRQVMYWLDP---VGG
MSMEG_6264|M.smegmatis_MC2_155      ADGTEVSAGTVVVATGAWTRPFLAPYGVDIPIRVIREQIVTISPGLDIGA
Mvan_5513|M.vanbaalenii_PYR-1       ADGSEIFAGTVVVATGVWTRPFLARYGIDVPIRVIREQIVLIDPGVEVGK
MAV_0142|M.avium_104                ADGTVLRADRVLICAGVATPKLFGPLG-----------------------
TH_2138|M.thermoresistible__bu      AGGQELSAGAVVIATGAWLHQLAQRWVR-VPVQAGRGYSFTVPVDRPVPA
                                    :      *  :::..*.    :                            

Mflv_3081|M.gilvum_PYR-GCK          TASFVDHP--IFIDENASGAQIYGFPAIDGPRGGVKVAFFRKGVECTPET
MMAR_4421|M.marinum_M               TAGFRDHP--IFIAENDSGAQIYGFPAIDGPRGGVKVAFFRKGIACTPDT
MSMEG_6264|M.smegmatis_MC2_155      VPVFSDLVSLQYVRPELGGEILFGNSDLG------------HGESADPDN
Mvan_5513|M.vanbaalenii_PYR-1       VPVFSDLVSLQYVRPEVGGEILFGNSDLPG---------YDAIDPADPDD
MAV_0142|M.avium_104                -VGFVPHTRFTYRGADATGAACLSAPEGYG-------------LPLGGTG
TH_2138|M.thermoresistible__bu      PVYLPEVR--VACTPCAAGLRVAG--------------------TMEFRD
                                       :              *    .                          

Mflv_3081|M.gilvum_PYR-GCK          IDRTVHDHEVREMRDRVAELLPALDGPCVHSATC-MYANTPDQHFVIARH
MMAR_4421|M.marinum_M               IDRVVGPQEIHEMITRVGELLPALAGTCLQAATC-MYSNTPDQHFVIARH
MSMEG_6264|M.smegmatis_MC2_155      YLNRATEEFVDITVEKVGTRFPGLTDASITGSYAGCYDVTPDWNPVISET
Mvan_5513|M.vanbaalenii_PYR-1       YLNRATDGFVDLTVDKVGTRFPGFPDAAISGSYAGCYDVTPDWNPIISVA
MAV_0142|M.avium_104                RWAFGQEVADPATVRALFPSLVAVDRVDCVSVRAPWLDSGGDGWTVARRG
TH_2138|M.thermoresistible__bu      PDAPLISKRVDAIVAAARPLLDGVRWDERGPSWVGPRPVTPDGRPLIGAV
                                                        : ..                 *   :    

Mflv_3081|M.gilvum_PYR-GCK          PDSERVTVACGFSGHGFKFVPVVGEILADLAISGATAHP--------ISL
MMAR_4421|M.marinum_M               PYCPAVTVACGFSGHGFKFVPVVGEILADLVTEGATSQP--------ISL
MSMEG_6264|M.smegmatis_MC2_155      D-VDGLIVAAGFSGHGFKIAPAVGRLVADLVVDGHSSDPRIPETDFRLSR
Mvan_5513|M.vanbaalenii_PYR-1       P-LDGLVIAAGFSGHGFKIAPAVGRLVADIVVDGHSSDSRIPASDFRFSR
MAV_0142|M.avium_104                R------VLAFVGANLMKFGPLLGELLARAALS---------------DD
TH_2138|M.thermoresistible__bu      A--EDVYVAAGHGMWGLTHGPVTGRLLAEQITTGKQP-----------DV
                                           : .  .   :.  *  *.::*                    . 

Mflv_3081|M.gilvum_PYR-GCK          FDPRRLVTTR----------
MMAR_4421|M.marinum_M               FDPQRLVTV-----------
MSMEG_6264|M.smegmatis_MC2_155      FAEDNLLKSPYPYVGAGEMR
Mvan_5513|M.vanbaalenii_PYR-1       FAEDDPLKTPYPYVGAGQMR
MAV_0142|M.avium_104                IPAELLLD------------
TH_2138|M.thermoresistible__bu      LDEFDPLR------------
                                    :     :