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IVVIGAGVCGLAAAHELSRRGHDDVVVLEKGQPFGEQSAGLARIFRIAHQREALCRLAFAARAGWQRWEA EFGVGRLLGSEGFIAAGAAADGVAQAMKRAGAAFSRLDRDGIAERIPFADVPWETGIFDPLGGSLRIRRA LTALARRVVIRCGEVVSVADDGRTVLADGTVLRADRVLICAGVATPKLFGPLGVGFVPHTRFTYRGADAT GAACLSAPEGYGLPLGGTGRWAFGQEVADPATVRALFPSLVAVDRVDCVSVRAPWLDSGGDGWTVARRGR VLAFVGANLMKFGPLLGELLARAALSDDIPAELLLD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0142 | - | - | 100% (317) | FAD dependent oxidoreductase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1296 | - | 4e-08 | 26.54% (211) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2651c | - | 4e-05 | 27.31% (249) | oxidoreductase |
| M. marinum M | MMAR_2926 | - | 2e-24 | 32.13% (361) | glycine/D-amino acid oxidase |
| M. smegmatis MC2 155 | MSMEG_6264 | - | 2e-08 | 27.96% (211) | putative oxidoreductase |
| M. thermoresistible (build 8) | TH_2450 | - | 6e-06 | 54.29% (35) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5513 | - | 1e-09 | 27.01% (211) | FAD dependent oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1296|M.gilvum_PYR-GCK ---------------------MTETADVVIVGGGLEGAAAAWALSRRGVT
Mvan_5513|M.vanbaalenii_PYR-1 ---------------------MTETADVVIVGGGLEGAAAAWALSRRGVT
MSMEG_6264|M.smegmatis_MC2_155 ---------------------MSITADVVIVGGGLEGTAAAWALSQRGVT
MMAR_2926|M.marinum_M ----------------------MRCTDVGVVGAGIVGLATAYALSLGGIS
MAV_0142|M.avium_104 --------------------------MIVVIGAGVCGLAAAHELSRRGHD
MAB_2651c|M.abscessus_ATCC_199 MEYLFDTGWVDRPEVTAAALQGEIRCDVAVIGAGVGGMAAGLRLAERGVD
TH_2450|M.thermoresistible__bu ---------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLRRRGIT
: ::*.* * *:. * *
Mflv_1296|M.gilvum_PYR-GCK DVVVCERS------------------------TVGSGMTGKSSGIVRCHY
Mvan_5513|M.vanbaalenii_PYR-1 DVVVAERN------------------------TVGSGMTGKSSGIVRCHY
MSMEG_6264|M.smegmatis_MC2_155 DVVVAERN------------------------TVGSGMTGKSSGIVRCHY
MMAR_2926|M.marinum_M -VTVYERG------------------------VPGHGQSGGESRIFRHAH
MAV_0142|M.avium_104 DVVVLEKG------------------------QPFGEQSAGLARIFRIAH
MAB_2651c|M.abscessus_ATCC_199 -VVVLEAG------------------------ICGWGASSRNGGYLTDAL
TH_2450|M.thermoresistible__bu DIAILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGP
:.: * . . . .
Mflv_1296|M.gilvum_PYR-GCK G-----VSSLAAMAADGLE------VFEQAQDIFGT-DIGFRQ-------
Mvan_5513|M.vanbaalenii_PYR-1 G-----VSSLAAMAADGLE------VFENGEDIFGT-DIGFRQ-------
MSMEG_6264|M.smegmatis_MC2_155 G-----VSSLAAMAAVGLD------VFEKAEEIFGD-DIGFRQ-------
MMAR_2926|M.marinum_M D-----DARMVALAKRSRR------IWDEWGRRLGV-ELLCSD-------
MAV_0142|M.avium_104 Q-----REALCRLAFAARA------GWQRWEAEFGVGRLLGSE-------
MAB_2651c|M.abscessus_ATCC_199 SGDPRMLSALHRRRLPGVM------RFGQSALRFAEDLIERHQI-----E
TH_2450|M.thermoresistible__bu EIHRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRPPVTAR
. . : :
Mflv_1296|M.gilvum_PYR-GCK -TGYVVGVGEQNVDALRKSLAAQRSVGVETEEIDESEVARLWPFADLTPF
Mvan_5513|M.vanbaalenii_PYR-1 -TGYVVGVGEQNVESLRKSLAAQRAVGVDTEEIDKDEVAKLWPFADLTPF
MSMEG_6264|M.smegmatis_MC2_155 -TGYVVGVGEQNVDALRKSLAAQRQVGVQTEEIDASEVAKLWPWADLEPF
MMAR_2926|M.marinum_M -GVVAIGPVAERRLGVLEAVGDCPARRIGADELHR----RLPIYADFDGV
MAV_0142|M.avium_104 -GFIAAGAAADGVAQAMKRAGAAFSR------LDRDGIAERIPFADVP-W
MAB_2651c|M.abscessus_ATCC_199 CDYNRVGWVSMASTTRHRAKNAERAAEVLRSLGADAEYVDGREFGLPHAF
TH_2450|M.thermoresistible__bu FVISSVGGYVNARATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAVIGTG
* . .
Mflv_1296|M.gilvum_PYR-GCK AAFGWEARGGYGDAYQTAQAFSTSARAAGVRVRQGTAVAGLLADADRVTG
Mvan_5513|M.vanbaalenii_PYR-1 AAFGWEARGGYGDAYQTAQAFSTAARAAGARVRQGTAVTDLLVDGDRVTG
MSMEG_6264|M.smegmatis_MC2_155 AAFGWEARGGYGDAYQTAQAFAIAARAAGVRIRQGATVTELLMGADRVTG
MMAR_2926|M.marinum_M AVL--DERGG---AIRTTRAISALTAALADRLVTDEVLLVRTTSAG-TVE
MAV_0142|M.avium_104 ETGIFDPLGG---SLRIRRALTALARRVVIRCG-------EVVSVADDGR
MAB_2651c|M.abscessus_ATCC_199 LGGVYEPHGGLCNAGKYALGLRKVLLASGARVYEQTP-VQDLESSGSAVV
TH_2450|M.thermoresistible__bu SSGAQIVSALSGRVARLDVYQRTPNWILPRPDFALPRALQRVLELPGVAA
. :
Mflv_1296|M.gilvum_PYR-GCK VRLADGSEISAGTTVVATGVWTRPFLSAHGIDMPIRVVREQIVMI--DPG
Mvan_5513|M.vanbaalenii_PYR-1 VRTADGSEIFAGTVVVATGVWTRPFLARYGIDVPIRVIREQIVLI--DPG
MSMEG_6264|M.smegmatis_MC2_155 VRLADGTEVSAGTVVVATGAWTRPFLAPYGVDIPIRVIREQIVTI--SPG
MMAR_2926|M.marinum_M VRTG-GAVAEHGRLVVCAGRGTAALARGVGLALPVREGAHVRLTYRVRG-
MAV_0142|M.avium_104 TVLADGTVLRADRVLICAGVATPKLFGPLGVGFVP----HTRFTYR----
MAB_2651c|M.abscessus_ATCC_199 ITVPGGKVRADRVLLATNGYSADLPFAPPRLAAPLWVSLLETEPIDPERL
TH_2450|M.thermoresistible__bu VLHNIGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFAFRVLLR
* : :
Mflv_1296|M.gilvum_PYR-GCK IDEAAVGRLPVFSDLVSLQYVRPELGGEILFGNSDLPGYDAIAPADPDAY
Mvan_5513|M.vanbaalenii_PYR-1 V---EVGKVPVFSDLVSLQYVRPEVGGEILFGNSDLPGYDAIDPADPDDY
MSMEG_6264|M.smegmatis_MC2_155 L---DIGAVPVFSDLVSLQYVRPELGGEILFGNSDLG---HGESADPDNY
MMAR_2926|M.marinum_M ---------EPPPRLACLQDGATGFGETGIYAAAEAG--NRRYAVGLNEY
MAV_0142|M.avium_104 --------------------GADATGAACLSAPEGYG-----LPLG-GTG
MAB_2651c|M.abscessus_ATCC_199 DS-------TGWTNGAGFVSNNNIVSNFRKTPHNTIVFGTRNVQAPQGPL
TH_2450|M.thermoresistible__bu AVVHDPQTRRRLMPAHGILAKRPIISGSYLPAFNDPRTHLITTPIERITA
.
Mflv_1296|M.gilvum_PYR-GCK LNRATDDFVD---------------------------------LTVDKVG
Mvan_5513|M.vanbaalenii_PYR-1 LNRATDGFVD---------------------------------LTVDKVG
MSMEG_6264|M.smegmatis_MC2_155 LNRATEEFVD---------------------------------ITVEKVG
MMAR_2926|M.marinum_M VDAPGGGLLAP--------------------------------AALARLG
MAV_0142|M.avium_104 RWAFGQEVADP--------------------------------ATVRALF
MAB_2651c|M.abscessus_ATCC_199 GARTTDPAVAK--------------------------------DLLRGFR
TH_2450|M.thermoresistible__bu AGVRTTDGVERPVDLIVTATGYELWTDPETYFPGTILGDAGFDLALDYRE
:
Mflv_1296|M.gilvum_PYR-GCK TRFPGFPDASITGSYAGCYDVTPDWNPVISRGP-------LDGLVIAAGF
Mvan_5513|M.vanbaalenii_PYR-1 TRFPGFPDAAISGSYAGCYDVTPDWNPIISVAP-------LDGLVIAAGF
MSMEG_6264|M.smegmatis_MC2_155 TRFPGLTDASITGSYAGCYDVTPDWNPVISETD-------VDGLIVAAGF
MMAR_2926|M.marinum_M ERANAYVERALPGLDPAPVDIRHCWVTELPWGSDGVGVWQHDGIFFIAGH
MAV_0142|M.avium_104 PSLVAVDRVDCVSVRAPWLDSGGDGWTVARRGR----------VLAFVGA
MAB_2651c|M.abscessus_ATCC_199 EAFPSLRDVATQKTWGGWIGMSPTLLPVAGQSS--------SRVLYTNGC
TH_2450|M.thermoresistible__bu NGLRSYGGTAHPRLPNRWEIVGPLAFVGVGWTDFVET-MAEHAVRIIDAA
. : .
Mflv_1296|M.gilvum_PYR-GCK SGHGFKIAPAVGRLVADLVVDGHGSDPR--------IPASDFRFSRFAEN
Mvan_5513|M.vanbaalenii_PYR-1 SGHGFKIAPAVGRLVADIVVDGHSSDSR--------IPASDFRFSRFAED
MSMEG_6264|M.smegmatis_MC2_155 SGHGFKIAPAVGRLVADLVVDGHSSDPR--------IPETDFRLSRFAED
MMAR_2926|M.marinum_M N--LFKHAPALGSELAAAAGGDHLFDDL--------RPEAQLGS------
MAV_0142|M.avium_104 N--LMKFGPLLGELLARAALSDDIPAEL--------LLD-----------
MAB_2651c|M.abscessus_ATCC_199 NGYGMTQAPYLATLLADRLAGDEMHEDLRAVWYDHNVFPPNPQFSALGAR
TH_2450|M.thermoresistible__bu RRRGADVVTVTDEAFGRWDARMRKAGKAARLYYTRCNPGVNTYYVNSQRD
. ..
Mflv_1296|M.gilvum_PYR-GCK DPLKTPYPYVGAGQMR---------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 DPLKTPYPYVGAGQMR---------------------------------
MSMEG_6264|M.smegmatis_MC2_155 NLLKSPYPYVGAGEMR---------------------------------
MMAR_2926|M.marinum_M ---RSPQ------------------------------------------
MAV_0142|M.avium_104 -------------------------------------------------
MAB_2651c|M.abscessus_ATCC_199 ALWTLDRITDQVDRLRS--------------------------------
TH_2450|M.thermoresistible__bu TVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSAVRALRHAEGNEAV