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M. smegmatis MC2 155 MSMEG_3319 (-)

annotation: repressor protein
coordinates: 3398604 - 3399185
length: 193

VQRRRGSALESAILDAGWDQLIEAGYDGFTIEAVATRSGSARSVLYRRWPSRLDLLKAVIRHRGEIDRIP
VPDTGTLRDDVVAVLTEFNDRRSRIIGIIAARLGAYFDEPDGSPKQLRDLFLSDGPTAMETIVERAVQRG
ELAAVPPARIVSLPADLVRHELLMTMTAVPADTIREIVDDIFLPLATRSGQER
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3319--100% (193)repressor protein
M. smegmatis MC2 155MSMEG_0465-4e-1330.43% (184) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_3834-5e-1330.26% (152) putative TetR-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1581-2e-1530.85% (188) regulatory protein
M. gilvum PYR-GCKMflv_3683-4e-2033.33% (189) TetR family transcriptional regulator
M. tuberculosis H37RvRv1556-2e-1530.85% (188) regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3151-7e-1629.84% (191) TetR family transcriptional regulator
M. marinum MMMAR_1695-3e-1329.19% (185) regulatory protein
M. avium 104MAV_4754-1e-1430.53% (190) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0688-4e-1035.00% (100) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_1934-2e-1329.19% (185) regulatory protein
M. vanbaalenii PYR-1Mvan_5902-3e-8480.53% (190) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb1581|M.bovis_AF2122/97            -----MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDA
Rv1556|M.tuberculosis_H37Rv         -----MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDA
MMAR_1695|M.marinum_M               ---------MTQTADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDA
MUL_1934|M.ulcerans_Agy99           ------MGAMTQTADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDA
MSMEG_3319|M.smegmatis_MC2_155      -----------------MQRRRGSALESAILDAGWDQLIEAGYDGFTIEA
Mvan_5902|M.vanbaalenii_PYR-1       ----------MSSTNSEVQRRRGAALESAILDAGWEQLIEAGYERFTIDA
Mflv_3683|M.gilvum_PYR-GCK          ----------------MMTRRRGAELDAAIRSAVLDLLAGHGPEAVTMDA
MAB_3151|M.abscessus_ATCC_1997      ------MTKNAATQRQRTSGRLNRSLDIAILEAAFVTLAEQGYDAMSMDN
MAV_4754|M.avium_104                MGQPQSQMEPESKLRQRTEGRLDRSRDPAILDAALAALAEHGYDATNMND
TH_0688|M.thermoresistible__bu      ----MTTNSTSVDKAAGAGRPRDPRIDGAILRATADLLVEIGYSNLTMSA
                                                              :  :  .    *   * .  .:. 

Mb1581|M.bovis_AF2122/97            VAASARASKATVYRRWPSKAELVLAAFIEGIR---QVAVPPNTGNLRDDL
Rv1556|M.tuberculosis_H37Rv         VAASARASKATVYRRWPSKAELVLAAFIEGIR---QVAVPPNTGNLRDDL
MMAR_1695|M.marinum_M               VANTARASKATVYRRWPSKAELVLAAFIEGVR---QVAVAPNTGSLRDDL
MUL_1934|M.ulcerans_Agy99           VANTARASKATVYRRWPSKAELVLAAFIEGVR---QVAVAPNTGSLRDDL
MSMEG_3319|M.smegmatis_MC2_155      VATRSGSARSVLYRRWPSRLDLLKAVIRHRG--EIDRIPVPDTGTLRDDV
Mvan_5902|M.vanbaalenii_PYR-1       VASRSGSARSVLYRRWPSRLDLLKAVIRHRG--EVDMIPTPDTGTLRGDV
Mflv_3683|M.gilvum_PYR-GCK          VAVAAGTSKPVLYRRWPDRRALLRDTLMAVA--STS-FPRPDTGTFRGDL
MAB_3151|M.abscessus_ATCC_1997      IAARAGVGKAAIYRRWSSKAALTADAILHGRPSLGKLDEVPDTGSLRGDL
MAV_4754|M.avium_104                IAARAGVGKAAIYRRWSSKAALMTDALIYWRPELLN-DDAPDTGSLAGDL
TH_0688|M.thermoresistible__bu      VAERAGTTKTALYRRWSSKPELVYAATAPTDP----VDTVESSDDVAGIV
                                    :*  :   :..:****..:  *   .               .:. . . :

Mb1581|M.bovis_AF2122/97            LRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRKALIQ
Rv1556|M.tuberculosis_H37Rv         LRLGELICREVGQHAS--TIRAVLVEVSRNPALNDVLQHQFVDHRKALIQ
MMAR_1695|M.marinum_M               VKIGEGICGQAHQQAS--TIRAVLVEVSRHPALSDALQRQFVDQRKALIQ
MUL_1934|M.ulcerans_Agy99           VKIGEGICGQAHQQAS--TIRAVLVEVSRHPALSDALQRQFVDQRKALIQ
MSMEG_3319|M.smegmatis_MC2_155      VAVLTEFN-DRRSRIIGIIAARLGAYFDEPDGSPKQLRDLFLSDGPTAME
Mvan_5902|M.vanbaalenii_PYR-1       LAILTAFN-DRRSRTIGLLAARLGAYFDEAGGSPHELRSLFVPQGPSSME
Mflv_3683|M.gilvum_PYR-GCK          LAVLRAWA-QLFTGDTGPLMRSVIVAVASDPDLESTFRSDVLGMRKAEMT
MAB_3151|M.abscessus_ATCC_1997      HSLYEARDFGDDQVLTGNLLAGIIAEAVNDPTLAAALDDLLVSQTHKRME
MAV_4754|M.avium_104                DAIVKRAKRNDNALISNDLVLRVALEAAHDPELATALNDLILFKGRRVLS
TH_0688|M.thermoresistible__bu      RALIERNRQITATPAARAAMPGLLVDMAADPRLHRGLLGRVG-SLVEALR
                                      :                   :             :   .       : 

Mb1581|M.bovis_AF2122/97            YILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVD
Rv1556|M.tuberculosis_H37Rv         YILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVD
MMAR_1695|M.marinum_M               QVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQLLVD
MUL_1934|M.ulcerans_Agy99           QVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQLLVD
MSMEG_3319|M.smegmatis_MC2_155      TIVERAVQRGELAAVPPARIV-SLPADLVRHELLMTMTAVPADTIREIVD
Mvan_5902|M.vanbaalenii_PYR-1       KIVERAVLRGELAAMPPARVV-SLPADLLRHELLMTMTAVSPQTILEIVD
Mflv_3683|M.gilvum_PYR-GCK          TLIGRAVERGEVRPDVPVELVRELGQSVLWHRLLITGDPITDELVTQLVD
MAB_3151|M.abscessus_ATCC_1997      LVFARAVERGEITQGRDLSLVYDIPLGLSLTAALK-RTVIDETYMHRMVE
MAV_4754|M.avium_104                AVLAQAADRGEIDPNRDWSLVADVLTAMGLLRAIS-GQRVDGKFVRRVID
TH_0688|M.thermoresistible__bu      RRLAEAAGRGEVQSGVDADRLTELIGGSVMFRMVLHPDEPITERWADEVA
                                      . .*. ***:        : .:         :              : 

Mb1581|M.bovis_AF2122/97            DVILPSLTRSTG---------------
Rv1556|M.tuberculosis_H37Rv         DVILPSLTRSTG---------------
MMAR_1695|M.marinum_M               DFIMPGLTQATG---------------
MUL_1934|M.ulcerans_Agy99           DFIMPGLTQATG---------------
MSMEG_3319|M.smegmatis_MC2_155      DIFLPLATRSGQ--ER-----------
Mvan_5902|M.vanbaalenii_PYR-1       DIFLPLATHFGTNITRGEPSAPPRSEP
Mflv_3683|M.gilvum_PYR-GCK          EVLIPVTRPYYDQ--------------
MAB_3151|M.abscessus_ATCC_1997      EVILPLVQAPTTHT-------------
MAV_4754|M.avium_104                TLILPAVRAAPE---------------
TH_0688|M.thermoresistible__bu      AILIRGVTKEG----------------
                                     .::