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VTADEPLLAPLAAEEWGDDEYAAFGALLGLPGEKVPRAGSGHDADPLKFDIIGLLARHPKMARRFLTFNG WLLQRGELPLRLRELAILRVAVTRRSEFFWGEHAKVALEGGVSEDDINRLAGDIEGFSGVDRVILEVTDE LLRDGRAEPDSWHRLVDELDTHQAMELVFVVGTYAMLAMAFDTWRLAPPAGSAPLPEPPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2330 | - | - | 100% (200) | carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_2440 | - | 5e-28 | 37.02% (181) | carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_2473 | - | 4e-23 | 33.70% (184) | carboxymuconolactone decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1558 | - | 2e-14 | 30.63% (160) | hypothetical protein Mb1558 |
| M. tuberculosis H37Rv | Rv1531 | - | 2e-14 | 30.63% (160) | hypothetical protein Rv1531 |
| M. leprae Br4923 | MLBr_02465 | - | 5e-08 | 30.47% (128) | hypothetical protein MLBr_02465 |
| M. abscessus ATCC 19977 | MAB_2040c | - | 5e-11 | 27.78% (162) | hypothetical protein MAB_2040c |
| M. marinum M | MMAR_4743 | - | 4e-23 | 36.16% (177) | hypothetical protein MMAR_4743 |
| M. avium 104 | MAV_3958 | pcaC | 4e-24 | 32.20% (177) | hypothetical protein MAV_3958 |
| M. smegmatis MC2 155 | MSMEG_4839 | - | 6e-28 | 36.41% (184) | carboxymuconolactone decarboxylase |
| M. thermoresistible (build 8) | TH_2018 | - | 3e-27 | 37.63% (186) | carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_4533 | - | 1e-05 | 26.15% (195) | hypothetical protein MUL_4533 |
| M. vanbaalenii PYR-1 | Mvan_4316 | - | 1e-92 | 83.16% (196) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1558|M.bovis_AF2122/97 ------------------------MTTS-RVPLLPVDEAKAAADEAGV--
Rv1531|M.tuberculosis_H37Rv ------------------------MTTS-RVPLLPVDEAKAAADEAGV--
MAB_2040c|M.abscessus_ATCC_199 ------------------------MTMAERVPMLDREQAQLRAAECGL--
Mflv_2330|M.gilvum_PYR-GCK --------------------MTADEPLLAPLAAEEWGDDEYAAFGALLGL
Mvan_4316|M.vanbaalenii_PYR-1 MPFEPRPSHPRQRRTQHMNSTDGAESLLAPLTAAEWGDDEYAAFGALLGL
MSMEG_4839|M.smegmatis_MC2_155 -------------------------MRLTPLPADEWDDEVRLALSVML--
TH_2018|M.thermoresistible__bu -------------------------VRLAPLPAEQWDDEVLSALAVML--
MMAR_4743|M.marinum_M -------------------------MRLPPLPADQWDEAVQRSLSVIL--
MAV_3958|M.avium_104 -----------------MAASDRHPQRLTPLPADEWDEDTRAALASLI--
MLBr_02465|M.leprae_Br4923 ------------------MSGGTGTGPVGRIPPGSLRQLGPINWVIAKLA
MUL_4533|M.ulcerans_Agy99 ------------------MTG----DQVARIPSGGIRQLGPVNWALAKLA
:. :
Mb1558|M.bovis_AF2122/97 PDYMAEL------------SIFQVLLNHPRLARTFNDLLATMLWHGTLDS
Rv1531|M.tuberculosis_H37Rv PDYMAEL------------SIFQVLLNHPRLARTFNDLLATMLWHGTLDS
MAB_2040c|M.abscessus_ATCC_199 PEELAEL------------SVFRVALHQPRVAVALYGLLDALLFRGSLDA
Mflv_2330|M.gilvum_PYR-GCK PGEKVPRAGSGHDADPLKFDIIGLLARHPKMARRFLTFNGWLLQRGELPL
Mvan_4316|M.vanbaalenii_PYR-1 PGEKVPRAGSGHAADPLKFDIIGLLARHPKMARRFLTFNGWLLQCGELPL
MSMEG_4839|M.smegmatis_MC2_155 PEERLNPEGAG--------TALSTLARHPRLTKAFLRFSNHLLFRSTLDP
TH_2018|M.thermoresistible__bu PEERRNPDGAG--------TALSTLVRHPRLTKAFLRFSNHLLFRSTLPP
MMAR_4743|M.marinum_M PAQRCNPRDAG--------NALSTFANHPALAKAFLRFNTHLLFASTLPA
MAV_3958|M.avium_104 PAERANPVGAG--------NVLSTLVRHPDLTAAYLPFNAYLLTRSTLSP
MLBr_02465|M.leprae_Br4923 ASLLRTS----------EMHLFTILGQRQLLFWAWLIYGGRLLR-GKLPR
MUL_4533|M.ulcerans_Agy99 ARSVRAP----------EMHLFTALGYRQYLFWTWAIYSGRLLH-GRLPR
. : : : :* . *
Mb1558|M.bovis_AF2122/97 RLRELVIMRIGWLTDCDYEWTQHWRVASGLGVSADDLLGVRDWQGYNGFG
Rv1531|M.tuberculosis_H37Rv RLRELVIMRIGWLTDCDYEWTQHWRVASGLGVSADDLLGVRDWQGYNGFG
MAB_2040c|M.abscessus_ATCC_199 RLRELVILRIGWITGSEYEWTQHWRIATLLGVPERDLLAVRDWQNSESLG
Mflv_2330|M.gilvum_PYR-GCK RLRELAILRVAVTRRSEFFWGEHAKVALEGGVSEDDINRLAGDI--EGFS
Mvan_4316|M.vanbaalenii_PYR-1 RLRELAILRIAHTRRSAFFWGEHTKVATEGGVPEADIARLAEGN--EAFT
MSMEG_4839|M.smegmatis_MC2_155 RLRELAILRIARRRNCEYEWAHHAFIGKAEGLTDDDIDGIGRG---VVSD
TH_2018|M.thermoresistible__bu RLRELAVLRVAHRRSCDYEWAHHVFIGKAEGLTDDDIAGVQRG---AVDD
MMAR_4743|M.marinum_M RVRELAILRVAHRRACAYEWTHHVALAEQAGISGDEIAAVRRG---EATD
MAV_3958|M.avium_104 RIREVALLRVVHRSKCGYLWSHHLPIARRAGLSESDIDDIRRG---RCAD
MLBr_02465|M.leprae_Br4923 VDTELVILRVAHLRTCEYELQHHRRMARKRGLDTKIQAMIFAWPDVPTGA
MUL_4533|M.ulcerans_Agy99 IDTELVILRVAHLRSCEYELQHHRRMARAAGLDAHAQATIFAWPDAPQGD
*:.::*: . : .* :. *: :
Mb1558|M.bovis_AF2122/97 P-------AEQAVLAATDDVVREGAVSAQSWSACERELHCDKVVLIELVT
Rv1531|M.tuberculosis_H37Rv P-------AEQAVLAATDDVVREGAVSAQSWSACERELHCDKVVLIELVT
MAB_2040c|M.abscessus_ATCC_199 P-------VERAVLAATDDVVRDGVISEENWAGCQKAFNSDHAVLVELVG
Mflv_2330|M.gilvum_PYR-GCK G-------VDRVILEVTDELLRDGRAEPDSWHRLVDELDTHQA--MELVF
Mvan_4316|M.vanbaalenii_PYR-1 G-------ADRLVLDATDELLHDGHAEPATWHRLTDELGTHQA--MELIF
MSMEG_4839|M.smegmatis_MC2_155 P-------FDQVVIDAVDELDELSTISDPTWAALGEKLDDRQR--MDLVF
TH_2018|M.thermoresistible__bu P-------FDQAVLDAVDELEEHYRISDATWATLGARLDERQL--MDLVF
MMAR_4743|M.marinum_M D-------FERAVLTGVDELDENSELSDQTWAALGEHLDDRQR--MDYVF
MAV_3958|M.avium_104 P-------TDAAVVRAVDELTGESTLSRQTWDRLCELFTQRQC--MDLIF
MLBr_02465|M.leprae_Br4923 G----LSVRQQALLAATDEFVKDRKITSSSWQQLETHLDRRRL--IEFCM
MUL_4533|M.ulcerans_Agy99 GPRRVLSSRQQALLTATDELIKNRSVTPATWEQLEIHLNRRRL--IEFCL
: :: .*:. .* : : ::
Mb1558|M.bovis_AF2122/97 VISAWRMVASILHSLEVPLEDGVSSWPPDGLSPR------
Rv1531|M.tuberculosis_H37Rv VISAWRMVASILHSLEVPLEDGVSSWPPDGLSPR------
MAB_2040c|M.abscessus_ATCC_199 AIANWRLFSILLRSLNIPLESGTDGWPPDGRAPRRRD---
Mflv_2330|M.gilvum_PYR-GCK VVGTYAMLAMAFDTWRLAPPAGSAPLPEPPS---------
Mvan_4316|M.vanbaalenii_PYR-1 VVGTYAMLAMAFDTWRLPPPAGSASLPEPPAGVPPGGGTH
MSMEG_4839|M.smegmatis_MC2_155 TVGGYGLMAMAYNTFGIEPESGH-----------------
TH_2018|M.thermoresistible__bu TVGCYGLMAMAYNTFGITPETGR-----------------
MMAR_4743|M.marinum_M TVGCYALLAMAFNTFGVQLEELEQDRAER-----------
MAV_3958|M.avium_104 TIGGYLLLALAVNTFGVQEEEETR----------------
MLBr_02465|M.leprae_Br4923 LISQYDGLAATISSLDIPLDNSC-----------------
MUL_4533|M.ulcerans_Agy99 LATQYDALAATITALGVPLDNPR-----------------
: .: : :