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M. smegmatis MC2 155 MSMEG_4839 (-)

annotation: carboxymuconolactone decarboxylase
coordinates: 4935469 - 4935999
length: 176

VRLTPLPADEWDDEVRLALSVMLPEERLNPEGAGTALSTLARHPRLTKAFLRFSNHLLFRSTLDPRLREL
AILRIARRRNCEYEWAHHAFIGKAEGLTDDDIDGIGRGVVSDPFDQVVIDAVDELDELSTISDPTWAALG
EKLDDRQRMDLVFTVGGYGLMAMAYNTFGIEPESGH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4839--100% (176)carboxymuconolactone decarboxylase
M. smegmatis MC2 155MSMEG_6536-2e-4752.60% (173) carboxymuconolactone decarboxylase
M. smegmatis MC2 155MSMEG_0905pcaC2e-0829.85% (134) hypothetical protein MSMEG_0905

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1558-5e-1430.34% (145) hypothetical protein Mb1558
M. gilvum PYR-GCKMflv_2440-9e-5860.12% (173) carboxymuconolactone decarboxylase
M. tuberculosis H37RvRv1531-5e-1430.34% (145) hypothetical protein Rv1531
M. leprae Br4923MLBr_02465-5e-0728.26% (138) hypothetical protein MLBr_02465
M. abscessus ATCC 19977MAB_2040c-8e-1231.45% (159) hypothetical protein MAB_2040c
M. marinum MMMAR_4743-5e-5960.69% (173) hypothetical protein MMAR_4743
M. avium 104MAV_3958pcaC9e-5255.81% (172) hypothetical protein MAV_3958
M. thermoresistible (build 8)TH_2018-1e-7979.43% (175) carboxymuconolactone decarboxylase
M. ulcerans Agy99MUL_4533-5e-0829.91% (117) hypothetical protein MUL_4533
M. vanbaalenii PYR-1Mvan_4212-4e-5457.80% (173) carboxymuconolactone decarboxylase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1558|M.bovis_AF2122/97            -------MTTS-RVPLLPVDEAKAAADEAGVPDYMAELS----IFQVLLN
Rv1531|M.tuberculosis_H37Rv         -------MTTS-RVPLLPVDEAKAAADEAGVPDYMAELS----IFQVLLN
MAB_2040c|M.abscessus_ATCC_199      -------MTMAERVPMLDREQAQLRAAECGLPEELAELS----VFRVALH
MSMEG_4839|M.smegmatis_MC2_155      --------MRLTPLPADEWDDEVRLALSVMLPEERLNPEGAGTALSTLAR
TH_2018|M.thermoresistible__bu      --------VRLAPLPAEQWDDEVLSALAVMLPEERRNPDGAGTALSTLVR
MMAR_4743|M.marinum_M               --------MRLPPLPADQWDEAVQRSLSVILPAQRCNPRDAGNALSTFAN
MAV_3958|M.avium_104                MAASDRHPQRLTPLPADEWDEDTRAALASLIPAERANPVGAGNVLSTLVR
Mflv_2440|M.gilvum_PYR-GCK          --------MRVAPLPADQWDDTVDKALSGLMPEEMRNPETAGNLVATLVR
Mvan_4212|M.vanbaalenii_PYR-1       --------MRLAPLPADQWDGVAEQALSGLMPAELRNPETAGNLVGTLLR
MLBr_02465|M.leprae_Br4923          -MSGGTGTGPVGRIPPGSLRQLGPINWVIAKLAASLLRTSEMHLFTILGQ
MUL_4533|M.ulcerans_Agy99           -MTG----DQVARIPSGGIRQLGPVNWALAKLAARSVRAPEMHLFTALGY
                                                 :*                             .     

Mb1558|M.bovis_AF2122/97            HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVA
Rv1531|M.tuberculosis_H37Rv         HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVA
MAB_2040c|M.abscessus_ATCC_199      QPRVAVALYGLLDALLFRGSLDARLRELVILRIGWITGSEYEWTQHWRIA
MSMEG_4839|M.smegmatis_MC2_155      HPRLTKAFLRFSNHLLFRSTLDPRLRELAILRIARRRNCEYEWAHHAFIG
TH_2018|M.thermoresistible__bu      HPRLTKAFLRFSNHLLFRSTLPPRLRELAVLRVAHRRSCDYEWAHHVFIG
MMAR_4743|M.marinum_M               HPALAKAFLRFNTHLLFASTLPARVRELAILRVAHRRACAYEWTHHVALA
MAV_3958|M.avium_104                HPDLTAAYLPFNAYLLTRSTLSPRIREVALLRVVHRSKCGYLWSHHLPIA
Mflv_2440|M.gilvum_PYR-GCK          HPRLAKGFLRFNFHLLYGSSLPARLRELAVLRIAHLTKCEYEWLHHVEMG
Mvan_4212|M.vanbaalenii_PYR-1       HPKLARAFLRFNFQLLYGTTLPERLREFVVLRVARLSNCEYEWRHHVAMG
MLBr_02465|M.leprae_Br4923          RQLLFWAWLIYGGRLLRG-KLPRVDTELVILRVAHLRTCEYELQHHRRMA
MUL_4533|M.ulcerans_Agy99           RQYLFWTWAIYSGRLLHG-RLPRIDTELVILRVAHLRSCEYELQHHRRMA
                                    :  :          :*    *     *..::*:     . *   :*  :.

Mb1558|M.bovis_AF2122/97            SGLGVSADDLLGVRDWQGYN-------GFGPAEQAVLAATDDVVREGAVS
Rv1531|M.tuberculosis_H37Rv         SGLGVSADDLLGVRDWQGYN-------GFGPAEQAVLAATDDVVREGAVS
MAB_2040c|M.abscessus_ATCC_199      TLLGVPERDLLAVRDWQNSE-------SLGPVERAVLAATDDVVRDGVIS
MSMEG_4839|M.smegmatis_MC2_155      KAEGLTDDDIDGIGRGV----------VSDPFDQVVIDAVDELDELSTIS
TH_2018|M.thermoresistible__bu      KAEGLTDDDIAGVQRGA----------VDDPFDQAVLDAVDELEEHYRIS
MMAR_4743|M.marinum_M               EQAGISGDEIAAVRRGE----------ATDDFERAVLTGVDELDENSELS
MAV_3958|M.avium_104                RRAGLSESDIDDIRRGR----------CADPTDAAVVRAVDELTGESTLS
Mflv_2440|M.gilvum_PYR-GCK          REAGLSDDVIDGITRGE----------ATDGLDRAVLNAVDELQNDSVVS
Mvan_4212|M.vanbaalenii_PYR-1       RDAGLSDDVIAGIERGE----------AVDEFDRAVLTAVDELHHDSVIS
MLBr_02465|M.leprae_Br4923          RKRGLDTKIQAMIFAWPDVPTGAG----LSVRQQALLAATDEFVKDRKIT
MUL_4533|M.ulcerans_Agy99           RAAGLDAHAQATIFAWPDAPQGDGPRRVLSSRQQALLTATDELIKNRSVT
                                       *:       :                .  : .:: ..*:.     ::

Mb1558|M.bovis_AF2122/97            AQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWP
Rv1531|M.tuberculosis_H37Rv         AQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWP
MAB_2040c|M.abscessus_ATCC_199      EENWAGCQKAFNSDHAVLVELVGAIANWRLFSILLRSLNIPLESGTDGWP
MSMEG_4839|M.smegmatis_MC2_155      DPTWAALGEKL--DDRQRMDLVFTVGGYGLMAMAYNTFGIEPESGH----
TH_2018|M.thermoresistible__bu      DATWATLGARL--DERQLMDLVFTVGCYGLMAMAYNTFGITPETGR----
MMAR_4743|M.marinum_M               DQTWAALGEHL--DDRQRMDYVFTVGCYALLAMAFNTFGVQLEELEQDRA
MAV_3958|M.avium_104                RQTWDRLCELF--TQRQCMDLIFTIGGYLLLALAVNTFGVQEEEETR---
Mflv_2440|M.gilvum_PYR-GCK          DATWTALSDHL--DERQLMDLVFTIGCYGALAMAINTFGVEPDQER----
Mvan_4212|M.vanbaalenii_PYR-1       DSTWTALSSHL--DERQLMDLVFTIGCYGALAMAINTFGVEPDQER----
MLBr_02465|M.leprae_Br4923          SSSWQQLETHL--DRRRLIEFCMLISQYDGLAATISSLDIPLDNSC----
MUL_4533|M.ulcerans_Agy99           PATWEQLEIHL--NRRRLIEFCLLATQYDALAATITALGVPLDNPR----
                                      .*      :       ::       :  .:    :: :  :       

Mb1558|M.bovis_AF2122/97            PDGLSPR---
Rv1531|M.tuberculosis_H37Rv         PDGLSPR---
MAB_2040c|M.abscessus_ATCC_199      PDGRAPRRRD
MSMEG_4839|M.smegmatis_MC2_155      ----------
TH_2018|M.thermoresistible__bu      ----------
MMAR_4743|M.marinum_M               ER--------
MAV_3958|M.avium_104                ----------
Mflv_2440|M.gilvum_PYR-GCK          ----------
Mvan_4212|M.vanbaalenii_PYR-1       ----------
MLBr_02465|M.leprae_Br4923          ----------
MUL_4533|M.ulcerans_Agy99           ----------