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RVAPLPADQWDDTVDKALSGLMPEEMRNPETAGNLVATLVRHPRLAKGFLRFNFHLLYGSSLPARLRELA VLRIAHLTKCEYEWLHHVEMGREAGLSDDVIDGITRGEATDGLDRAVLNAVDELQNDSVVSDATWTALSD HLDERQLMDLVFTIGCYGALAMAINTFGVEPDQER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2440 | - | - | 100% (176) | carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_2473 | - | 8e-51 | 51.16% (172) | carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_2330 | - | 4e-28 | 37.02% (181) | carboxymuconolactone decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1558 | - | 1e-16 | 31.03% (174) | hypothetical protein Mb1558 |
| M. tuberculosis H37Rv | Rv1531 | - | 1e-16 | 31.03% (174) | hypothetical protein Rv1531 |
| M. leprae Br4923 | MLBr_02465 | - | 2e-14 | 32.81% (128) | hypothetical protein MLBr_02465 |
| M. abscessus ATCC 19977 | MAB_4119 | - | 2e-16 | 32.28% (127) | hypothetical protein MAB_4119 |
| M. marinum M | MMAR_4743 | - | 2e-58 | 57.47% (174) | hypothetical protein MMAR_4743 |
| M. avium 104 | MAV_3958 | pcaC | 4e-47 | 50.57% (174) | hypothetical protein MAV_3958 |
| M. smegmatis MC2 155 | MSMEG_4839 | - | 1e-57 | 60.12% (173) | carboxymuconolactone decarboxylase |
| M. thermoresistible (build 8) | TH_2018 | - | 1e-61 | 61.93% (176) | carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_4533 | - | 9e-16 | 34.30% (172) | hypothetical protein MUL_4533 |
| M. vanbaalenii PYR-1 | Mvan_4212 | - | 4e-80 | 78.98% (176) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1558|M.bovis_AF2122/97 --------MTTSRVPLLPVDEAKAAADEAGVPDYMAELS----IFQVLLN
Rv1531|M.tuberculosis_H37Rv --------MTTSRVPLLPVDEAKAAADEAGVPDYMAELS----IFQVLLN
Mflv_2440|M.gilvum_PYR-GCK --------MRVAPLPADQWDDTVDKALSGLMPEEMRNPETAGNLVATLVR
Mvan_4212|M.vanbaalenii_PYR-1 --------MRLAPLPADQWDGVAEQALSGLMPAELRNPETAGNLVGTLLR
MSMEG_4839|M.smegmatis_MC2_155 --------MRLTPLPADEWDDEVRLALSVMLPEERLNPEGAGTALSTLAR
TH_2018|M.thermoresistible__bu --------VRLAPLPAEQWDDEVLSALAVMLPEERRNPDGAGTALSTLVR
MMAR_4743|M.marinum_M --------MRLPPLPADQWDEAVQRSLSVILPAQRCNPRDAGNALSTFAN
MAV_3958|M.avium_104 MAASDRHPQRLTPLPADEWDEDTRAALASLIPAERANPVGAGNVLSTLVR
MLBr_02465|M.leprae_Br4923 -MSGGTGTGPVGRIPPGSLRQLGPINWVIAKLAASLLRTSEMHLFTILGQ
MUL_4533|M.ulcerans_Agy99 -MTG----DQVARIPSGGIRQLGPVNWALAKLAARSVRAPEMHLFTALGY
MAB_4119|M.abscessus_ATCC_1997 -MSS-------GRIPSGGLRELGPINWVIAKGMARAVNAPEMHLATTLGQ
:* :
Mb1558|M.bovis_AF2122/97 HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVA
Rv1531|M.tuberculosis_H37Rv HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVA
Mflv_2440|M.gilvum_PYR-GCK HPRLAKGFLRFNFHLLYGSSLPARLRELAVLRIAHLTKCEYEWLHHVEMG
Mvan_4212|M.vanbaalenii_PYR-1 HPKLARAFLRFNFQLLYGTTLPERLREFVVLRVARLSNCEYEWRHHVAMG
MSMEG_4839|M.smegmatis_MC2_155 HPRLTKAFLRFSNHLLFRSTLDPRLRELAILRIARRRNCEYEWAHHAFIG
TH_2018|M.thermoresistible__bu HPRLTKAFLRFSNHLLFRSTLPPRLRELAVLRVAHRRSCDYEWAHHVFIG
MMAR_4743|M.marinum_M HPALAKAFLRFNTHLLFASTLPARVRELAILRVAHRRACAYEWTHHVALA
MAV_3958|M.avium_104 HPDLTAAYLPFNAYLLTRSTLSPRIREVALLRVVHRSKCGYLWSHHLPIA
MLBr_02465|M.leprae_Br4923 RQLLFWAWLIYGGRLLRG-KLPRVDTELVILRVAHLRTCEYELQHHRRMA
MUL_4533|M.ulcerans_Agy99 RQYLFWTWAIYSGRLLHG-RLPRIDTELVILRVAHLRSCEYELQHHRRMA
MAB_4119|M.abscessus_ATCC_1997 TGARFWPWLAYSGAILRGTKLSTRDTEVVILRVAHVRECEYELQHHTRIA
: :* * *..::*: * * :* :.
Mb1558|M.bovis_AF2122/97 SGLGVSADDLLGVRDW----QGYNG---FGPAEQAVLAATDDVVREGAVS
Rv1531|M.tuberculosis_H37Rv SGLGVSADDLLGVRDW----QGYNG---FGPAEQAVLAATDDVVREGAVS
Mflv_2440|M.gilvum_PYR-GCK REAGLSDDVIDGITRG----EATD------GLDRAVLNAVDELQNDSVVS
Mvan_4212|M.vanbaalenii_PYR-1 RDAGLSDDVIAGIERG----EAVD------EFDRAVLTAVDELHHDSVIS
MSMEG_4839|M.smegmatis_MC2_155 KAEGLTDDDIDGIGRG----VVSD------PFDQVVIDAVDELDELSTIS
TH_2018|M.thermoresistible__bu KAEGLTDDDIAGVQRG----AVDD------PFDQAVLDAVDELEEHYRIS
MMAR_4743|M.marinum_M EQAGISGDEIAAVRRG----EATD------DFERAVLTGVDELDENSELS
MAV_3958|M.avium_104 RRAGLSESDIDDIRRG----RCAD------PTDAAVVRAVDELTGESTLS
MLBr_02465|M.leprae_Br4923 RKRGLDTKIQAMIFAWPDVPTGAG----LSVRQQALLAATDEFVKDRKIT
MUL_4533|M.ulcerans_Agy99 RAAGLDAHAQATIFAWPDAPQGDGPRRVLSSRQQALLTATDELIKNRSVT
MAB_4119|M.abscessus_ATCC_1997 KSAGIDPAYQERIFTG---AGAEG----LSDKERALITGVDEILTTRTLS
*: : . : .:: ..*:. ::
Mb1558|M.bovis_AF2122/97 AQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWP
Rv1531|M.tuberculosis_H37Rv AQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWP
Mflv_2440|M.gilvum_PYR-GCK DATWTALS--DHLDERQLMDLVFTIGCYGALAMAINTFGVEPDQER----
Mvan_4212|M.vanbaalenii_PYR-1 DSTWTALS--SHLDERQLMDLVFTIGCYGALAMAINTFGVEPDQER----
MSMEG_4839|M.smegmatis_MC2_155 DPTWAALG--EKLDDRQRMDLVFTVGGYGLMAMAYNTFGIEPESGH----
TH_2018|M.thermoresistible__bu DATWATLG--ARLDERQLMDLVFTVGCYGLMAMAYNTFGITPETGR----
MMAR_4743|M.marinum_M DQTWAALG--EHLDDRQRMDYVFTVGCYALLAMAFNTFGVQLEELEQDRA
MAV_3958|M.avium_104 RQTWDRLC--ELFTQRQCMDLIFTIGGYLLLALAVNTFGVQEEEETR---
MLBr_02465|M.leprae_Br4923 SSSWQQLE--THLDRRRLIEFCMLISQYDGLAATISSLDIPLDNSC----
MUL_4533|M.ulcerans_Agy99 PATWEQLE--IHLNRRRLIEFCLLATQYDALAATITALGVPLDNPR----
MAB_4119|M.abscessus_ATCC_1997 DEAWEGLS--KFLDRRQLIGFCLLVTQYDGLAATMSSLRIPLDH------
:* : : :* :: : :
Mb1558|M.bovis_AF2122/97 PDGLSPR
Rv1531|M.tuberculosis_H37Rv PDGLSPR
Mflv_2440|M.gilvum_PYR-GCK -------
Mvan_4212|M.vanbaalenii_PYR-1 -------
MSMEG_4839|M.smegmatis_MC2_155 -------
TH_2018|M.thermoresistible__bu -------
MMAR_4743|M.marinum_M ER-----
MAV_3958|M.avium_104 -------
MLBr_02465|M.leprae_Br4923 -------
MUL_4533|M.ulcerans_Agy99 -------
MAB_4119|M.abscessus_ATCC_1997 -------