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MTRAVNDFRQRLLDALESSIAEDGYAKTTVADIVRRARTSRRTFYEHFDSREACFVALLSDANADQIRQI SDAVDPSAPWQKQVRQAIEAWISSGEARPALMLSWIRDVPSLGAVARGLQRDSLESFIDMVGALGATDEF RAAGVGPVSRPRIIMLLGGLRELTAITVEEGGRMSDVAEEAVDASIALLNPH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1674 | - | - | 100% (192) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1103 | - | 3e-47 | 51.10% (182) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3103 | - | 2e-09 | 26.47% (170) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0140c | - | 3e-49 | 52.69% (186) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv0135c | - | 3e-49 | 52.69% (186) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01070 | - | 4e-05 | 30.00% (90) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1149 | - | 2e-07 | 26.54% (162) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0345 | - | 8e-48 | 52.17% (184) | transcriptional regulatory protein |
| M. avium 104 | MAV_5161 | - | 5e-48 | 50.80% (187) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6480 | - | 2e-45 | 50.00% (182) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0083 | - | 3e-43 | 48.63% (183) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4775 | - | 7e-48 | 52.17% (184) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5079 | - | 6e-91 | 88.77% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1674|M.gilvum_PYR-GCK ----------MTRAVN-----------DFRQRLLDALESSIAEDGYAKTT
Mvan_5079|M.vanbaalenii_PYR-1 --------------MN-----------DFRQRLLDALEASIAEDGYARTT
MSMEG_6480|M.smegmatis_MC2_155 ----------MTTALTGTATAGGSGGDAFRSRLLDGLSTAIDDKGYRDST
TH_0083|M.thermoresistible__bu ----------MTTAVQ-PADVG-AGDDAFRGRLLSGLAASIAERGYRETT
Mb0140c|M.bovis_AF2122/97 ----------MTAVAAGALVVE---TDSFRLRLLDGLVASIGERGYRATT
Rv0135c|M.tuberculosis_H37Rv ----------MTAVAAGALVVE---TDSFRLRLLDGLVASIGERGYRATT
MMAR_0345|M.marinum_M ----------MTAAASSPAALD---SDPFRQRLLEGLVASIGERGYHATT
MUL_4775|M.ulcerans_Agy99 ----------MTAAASSPAALD---SDPFRQRLLEGLVASIGERGYHATT
MAV_5161|M.avium_104 ----------MTATDGEPDLGE---IDPFRLRLLDGLATSIGERGYRAST
MAB_1149|M.abscessus_ATCC_1997 ------MAVPSRPDVPGRTPRVRMAGSERRRQLIDVARSLFAERGYEATS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
. :: : : :
Mflv_1674|M.gilvum_PYR-GCK VADIVRRARTSRRTFYEHFDSREACFVALLSDANADQIRQISD-AVDPSA
Mvan_5079|M.vanbaalenii_PYR-1 VADIVRRAKTSRRTFYEHFDSREACFVALLSDANADQIRQIYA-AVDPSA
MSMEG_6480|M.smegmatis_MC2_155 VADIVRHARTSKRTFYDQFASKEACFIELLRANNAALVEHIRS-AVSPEA
TH_0083|M.thermoresistible__bu VADIVRHARTSKRTFYDQFGSKEECFQELLWANNIDMIGAIRA-AVDPEA
Mb0140c|M.bovis_AF2122/97 VSDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRA-AVDPNA
Rv0135c|M.tuberculosis_H37Rv VSDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRA-AVDPNA
MMAR_0345|M.marinum_M VADIVRHARTSKRTFYDRFESKEQCFLDLLRADNERLAKRIRA-AVDPEA
MUL_4775|M.ulcerans_Agy99 VADIVRHARTSKRTFYDRFESKEQCFLDLLRADNERLAKRIRA-AVDPEA
MAV_5161|M.avium_104 VADVVRCARTSKRTFYDHFAGKEECFLELLAVDIEKLGAKIAA-SVDPEA
MAB_1149|M.abscessus_ATCC_1997 IEEIAQRAGVSKPVVYEHFGGKEGLYAVVVDREMSVLLDGITS-SLT-SY
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: ::.: * *: ..* * .:: :: : :
Mflv_1674|M.gilvum_PYR-GCK PWQKQVRQAIEAWISSGEARPALMLSWIRDVPSLGAVARGLQRDSLESFI
Mvan_5079|M.vanbaalenii_PYR-1 PWQKQVRQAIEAWISSGEARSALMLSWIRDVPALGAAARGLQREAMEHFV
MSMEG_6480|M.smegmatis_MC2_155 EWQDQIDQAVGAYVEHIESAPSITLSWIRELPALGPAARPLQRDAMGALT
TH_0083|M.thermoresistible__bu DWSEQIRQAVVAYVDHIESRPAITLAWIRELPAIGASVRPIQRAMMHELT
Mb0140c|M.bovis_AF2122/97 DWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLT
Rv0135c|M.tuberculosis_H37Rv DWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLT
MMAR_0345|M.marinum_M DWQAQIRQAVEAYVSHIESRLAVTLSWIREFPSLGPISYPVQRHGMNLLT
MUL_4775|M.ulcerans_Agy99 DWQAQIRQAVEAYLSHIESRLAVTLSWIREFPSLGPISYPVQRHGMNLLT
MAV_5161|M.avium_104 DWHVQIRQAVEAYVGYIEARPAITLSWIRELPSLGAAARPVQRRGLQLLT
MAB_1149|M.abscessus_ATCC_1997 RSRVRLEQVALALLSYIEERTDGFRILIRDSPPG--VSSGTYSSLLNDAV
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
.. * . ..
Mflv_1674|M.gilvum_PYR-GCK DMVGALGATDEFRAAGVGPVSRPRIIMLLGGLRELTAITVEEGGRMSDVA
Mvan_5079|M.vanbaalenii_PYR-1 DMVGALGATDEFRAAGVGPFSRRRIIMLLGGLRELTASTVEEGGRMSDVT
MSMEG_6480|M.smegmatis_MC2_155 DLLIDLSDSPGFRRAGLNGLSRQMAIILLGGLRELTALIVEDGHDIREIY
TH_0083|M.thermoresistible__bu ELLIELSRSPGFARAQMPPLTRQLAVFLLGGLRELTALFVEDGRDVRGLI
Mb0140c|M.bovis_AF2122/97 SLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIV
Rv0135c|M.tuberculosis_H37Rv SLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIV
MMAR_0345|M.marinum_M SLLVELSASPGFRRAGLPAVPGALAVILLGGLRELTALTVEDGRDIREIV
MUL_4775|M.ulcerans_Agy99 SLLVELSASPGFRRAGLPAVPGALAVILLGGLRELTALTVEDGRDIREIV
MAV_5161|M.avium_104 SLLIDLSASPGFRRAQLPPLTAPLAVILLGGLRELTALAVEDGKPVRGIV
MAB_1149|M.abscessus_ATCC_1997 SQVSSILAG-DFQRRGLDAEMAPLYAQALVGQVSMTAQWWLDAREPKKEV
MLBr_01070|M.leprae_Br4923 YNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLIPDK
: : * :
Mflv_1674|M.gilvum_PYR-GCK EEAVDASIALLNPH-----------
Mvan_5079|M.vanbaalenii_PYR-1 DEAVEASIALLSPPAR---------
MSMEG_6480|M.smegmatis_MC2_155 EPAVAASRAILTASSAEHQAR----
TH_0083|M.thermoresistible__bu APAVSASKALLSAGASE--------
Mb0140c|M.bovis_AF2122/97 EPAVDASIALLGPRS----------
Rv0135c|M.tuberculosis_H37Rv EPAVDASIALLGPRS----------
MMAR_0345|M.marinum_M EPAVDASIALVGPRH----------
MUL_4775|M.ulcerans_Agy99 EPAVDASIALVGPRH----------
MAV_5161|M.avium_104 EPAVDASVALLGPRH----------
MAB_1149|M.abscessus_ATCC_1997 VAAHIVNLCWHGLKHLEADPQLHEE
MLBr_01070|M.leprae_Br4923 KVIDTLVHIWLASIYGS--------