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RSPTDRRQPQKSDLRRVAILESLNHHLRESGFDALNIAAVAKRAGVTRSAFYFYFENKAAAVAALLEPMY DDGFLASDILTDTTQPPARRVRAMLEALLDTVDEHRYLLQAMLEARATSAAIRHVWDEARETFVPTVAQM IASERAAGRAPDGPGPEMIAGILLEFNDRLMERHTLGGRLSRDELLTAAQSVWLRTIYANDGDELQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3103 | - | - | 100% (207) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0963 | - | 1e-14 | 27.80% (205) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4314 | - | 5e-13 | 30.92% (152) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 4e-15 | 26.96% (204) | transcriptional regulatory repressor protein (TETR-family) |
| M. tuberculosis H37Rv | Rv3855 | ethR | 4e-15 | 26.96% (204) | transcriptional regulatory repressor protein (TETR-family) |
| M. leprae Br4923 | MLBr_01070 | - | 1e-14 | 28.14% (199) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0984c | - | 3e-14 | 28.95% (190) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5405 | ethR | 9e-14 | 27.64% (199) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0173 | - | 1e-19 | 31.61% (193) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3874 | - | 3e-73 | 62.93% (205) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3269 | - | 3e-69 | 65.83% (199) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_5027 | ethR | 1e-13 | 27.64% (199) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3432 | - | 1e-90 | 78.92% (204) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3885|M.bovis_AF2122/97 ----MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADIS
Rv3855|M.tuberculosis_H37Rv ----MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADIS
MMAR_5405|M.marinum_M ---MVSTSTASQASPSRGRRSARPSGDERELAILNTAEKLLEDRPMVDIS
MUL_5027|M.ulcerans_Agy99 ----MSTSTASQASLSRGRRSARPSGDERELAILNTAEKLLEDRPMVDIS
MAV_0173|M.avium_104 ------MTTAGQTRALRGRRAIRPTGDEREQAILATALRLLETRPFAGIS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
MAB_0984c|M.abscessus_ATCC_199 ----------MTKPATRGRKTTRPSGDERIQAILATAEELLGKRPLADVS
Mflv_3103|M.gilvum_PYR-GCK ------------MRSPTDRRQPQKS-DLRRVAILESLNHHLRESGFDALN
Mvan_3432|M.vanbaalenii_PYR-1 ------MQRGLPVRSPTDRRQPQKS-DLRRSAILESLDQHLRESGFDGLN
MSMEG_3874|M.smegmatis_MC2_155 -----MVRPSTPVRSPTDRRQPQRS-DLRRTAILEALNEHLQKTGFDALN
TH_3269|M.thermoresistible__bu -----MAQHGLSVRSPTDRRQPLRS-DQRRTAILAALDEQLRVTGFERLN
.*: : * * *** . * : ..
Mb3885|M.bovis_AF2122/97 VDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPAD
Rv3855|M.tuberculosis_H37Rv VDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPAD
MMAR_5405|M.marinum_M VDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNLAQAP-D
MUL_5027|M.ulcerans_Agy99 VDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNLAQAP-D
MAV_0173|M.avium_104 VDDLAKGAGLSRPTFYFYFKSKEAVVLSLLEPVIARADAEFDGAVQRL-P
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQL-P
MAB_0984c|M.abscessus_ATCC_199 VDDLARGAGISRPTFYFYFSSKESVLLTLAERIIEEADANVASIDPAA-M
Mflv_3103|M.gilvum_PYR-GCK IAAVAKRAGVTRSAFYFYFENKAAAVAALLEPMYDDGFLASDILTDTTQP
Mvan_3432|M.vanbaalenii_PYR-1 IADVTRRAGVTRSAFYFYFENKAAAVAALLEPMYDDGFLAGDLLANIEQP
MSMEG_3874|M.smegmatis_MC2_155 IAEVARQAGVGRSAFYFYFENKAAAVAALLEPMHEALLAANNILADLTRP
TH_3269|M.thermoresistible__bu IAEVARQAGVTRSAFYFYFENKAAAVAALLDPMYDDVFAANDLLT-ADGD
: ::: **: *.:***** .* :.: :* : :
Mb3885|M.bovis_AF2122/97 TDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWI
Rv3855|M.tuberculosis_H37Rv TDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWI
MMAR_5405|M.marinum_M VDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISAEVRELWSTFMQKWI
MUL_5027|M.ulcerans_Agy99 VDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISTEVRELWSTFMQKWI
MAV_0173|M.avium_104 TDPRRVWRNGIKAFFTAFSSHRALARAATEALATSSELRSVWSGFMQKWI
MLBr_01070|M.leprae_Br4923 ADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWI
MAB_0984c|M.abscessus_ATCC_199 TSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQRWSEVTENWV
Mflv_3103|M.gilvum_PYR-GCK PARR--VRAMLEALLDTVDEHRYLLQAMLEARATSAAIRHVWDEARETFV
Mvan_3432|M.vanbaalenii_PYR-1 PRAR--IRAMLEALLDTVDQHRYLLQAMLEARASSTVIREVWDDARESFV
MSMEG_3874|M.smegmatis_MC2_155 PGER--IRATLDAVLRTAEDHRYLFQAMLEARGTSGAVRDMWDAARESFV
TH_3269|M.thermoresistible__bu PRQR--IRAMIETLLDTGERHRYLLQAMLEARAVSSSVRTLWDTARESFV
* : . : . *: : . . * : *. : ::
Mb3885|M.bovis_AF2122/97 AYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPE
Rv3855|M.tuberculosis_H37Rv AYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPE
MMAR_5405|M.marinum_M AYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFLAEEPSVPE
MUL_5027|M.ulcerans_Agy99 AYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFLAEEPSVPE
MAV_0173|M.avium_104 DQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPAVAE
MLBr_01070|M.leprae_Br4923 DYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLIPD
MAB_0984c|M.abscessus_ATCC_199 ANTTVGIEAERARGAAPSVVPARDIAIALNLINQAMMRATFTGQQPAVDD
Mflv_3103|M.gilvum_PYR-GCK PTVAQMIASERAAGRAPDGPGPEMIAGILLEFNDRLMERHTLG--GRLSR
Mvan_3432|M.vanbaalenii_PYR-1 PTVARMITAERDSGRAPAGSSAEVVASMLLEFNDRLMERHTLG--GRLGR
MSMEG_3874|M.smegmatis_MC2_155 PTVSAVITAERESGRAPDGVDPKVLASLLMEFNDRLLERLIIG--GPLTR
TH_3269|M.thermoresistible__bu PAVAAMIRTERSAGRAPDGCDPVVLATALLEFNDRLLERFTAG--TALSR
: * :** * ** . :* * :.: : :
Mb3885|M.bovis_AF2122/97 ARVLDTLVHIWVTSIYGENR-----------------------
Rv3855|M.tuberculosis_H37Rv ARVLDTLVHIWVTSIYGENR-----------------------
MMAR_5405|M.marinum_M THVVDTLVHIWVSSIYGEAR-----------------------
MUL_5027|M.ulcerans_Agy99 THVVDTLVHVWVSSIYGAAR-----------------------
MAV_0173|M.avium_104 DRVVDTLTHIWVSSIYGESG-----------------------
MLBr_01070|M.leprae_Br4923 KKVIDTLVHIWLASIYGS-------------------------
MAB_0984c|M.abscessus_ATCC_199 GKVVDTLLHVWLNAIYGGVCANS--------------------
Mflv_3103|M.gilvum_PYR-GCK DELLTAAQSVWLRTIYAN---------DGDELQ----------
Mvan_3432|M.vanbaalenii_PYR-1 DELLAGAETIWLRTIYAH---------DGDL------------
MSMEG_3874|M.smegmatis_MC2_155 RQLLEGAEAMWMGAIYAS---------EPEQTR----------
TH_3269|M.thermoresistible__bu QQLRDGAEAVWLGSIYPGPIGGPGPRPDPRPDRHPESTPSSRF
.: :*: :**