For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTATDGEPDLGEIDPFRLRLLDGLATSIGERGYRASTVADVVRCARTSKRTFYDHFAGKEECFLELLAVD IEKLGAKIAASVDPEADWHVQIRQAVEAYVGYIEARPAITLSWIRELPSLGAAARPVQRRGLQLLTSLLI DLSASPGFRRAQLPPLTAPLAVILLGGLRELTALAVEDGKPVRGIVEPAVDASVALLGPRH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5161 | - | - | 100% (201) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1948 | - | 2e-06 | 35.05% (97) | putative transcriptional regulator |
| M. avium 104 | MAV_2650 | - | 2e-06 | 30.61% (98) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0140c | - | 1e-81 | 78.84% (189) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1103 | - | 1e-58 | 62.98% (181) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0135c | - | 1e-81 | 78.84% (189) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1149 | - | 8e-07 | 27.67% (159) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0345 | - | 3e-75 | 69.15% (201) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6480 | - | 5e-60 | 65.22% (184) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0083 | - | 6e-66 | 70.27% (185) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4775 | - | 5e-75 | 68.66% (201) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5713 | - | 1e-58 | 64.25% (179) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1103|M.gilvum_PYR-GCK ----------------------MNDRLLDGLASSIVERGYRETTVADIVR
Mvan_5713|M.vanbaalenii_PYR-1 ----MRTTPLAAGPHP-----SVADRLLDGLASAITERGYRDSTVADVVR
Mb0140c|M.bovis_AF2122/97 ----MTAVAAGALVVE---TDSFRLRLLDGLVASIGERGYRATTVSDIVR
Rv0135c|M.tuberculosis_H37Rv ----MTAVAAGALVVE---TDSFRLRLLDGLVASIGERGYRATTVSDIVR
MMAR_0345|M.marinum_M ----MTAAASSPAALD---SDPFRQRLLEGLVASIGERGYHATTVADIVR
MUL_4775|M.ulcerans_Agy99 ----MTAAASSPAALD---SDPFRQRLLEGLVASIGERGYHATTVADIVR
MAV_5161|M.avium_104 ----MTATDGEPDLGE---IDPFRLRLLDGLATSIGERGYRASTVADVVR
MSMEG_6480|M.smegmatis_MC2_155 ----MTTALTGTATAGGSGGDAFRSRLLDGLSTAIDDKGYRDSTVADIVR
TH_0083|M.thermoresistible__bu ----MTTAVQ-PADVG-AGDDAFRGRLLSGLAASIAERGYRETTVADIVR
MAB_1149|M.abscessus_ATCC_1997 MAVPSRPDVPGRTPRVRMAGSERRRQLIDVARSLFAERGYEATSIEEIAQ
:*:. : : ::**. ::: ::.:
Mflv_1103|M.gilvum_PYR-GCK HAKTSKRAFYEQFASKEQCLIELLRNNNTDLIAHINAAVDPESDWREQIG
Mvan_5713|M.vanbaalenii_PYR-1 YARTSKRTFYEQFASKEECLIEMLRRNHSDLIAGIGAAVEPEADWRLQID
Mb0140c|M.bovis_AF2122/97 HARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADWHDQIR
Rv0135c|M.tuberculosis_H37Rv HARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADWHDQIR
MMAR_0345|M.marinum_M HARTSKRTFYDRFESKEQCFLDLLRADNERLAKRIRAAVDPEADWQAQIR
MUL_4775|M.ulcerans_Agy99 HARTSKRTFYDRFESKEQCFLDLLRADNERLAKRIRAAVDPEADWQAQIR
MAV_5161|M.avium_104 CARTSKRTFYDHFAGKEECFLELLAVDIEKLGAKIAASVDPEADWHVQIR
MSMEG_6480|M.smegmatis_MC2_155 HARTSKRTFYDQFASKEACFIELLRANNAALVEHIRSAVSPEAEWQDQID
TH_0083|M.thermoresistible__bu HARTSKRTFYDQFGSKEECFQELLWANNIDMIGAIRAAVDPEADWSEQIR
MAB_1149|M.abscessus_ATCC_1997 RAGVSKPVVYEHFGGKEGLYAVVVDREMSVLLDGITSSLTS-YRSRVRLE
* .** ..*::* .** :: : : * ::: . ::
Mflv_1103|M.gilvum_PYR-GCK QAVDAYIGHISARPAITLCWIREAPALGAVARPLHRQVMRDLTEMLTALT
Mvan_5713|M.vanbaalenii_PYR-1 KAVGAYIDHISARPAITLCWIREAPGLGAAARPLHRLVMGDLTDLLVSLT
Mb0140c|M.bovis_AF2122/97 QAVEAYVTHIESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLTSLLIELS
Rv0135c|M.tuberculosis_H37Rv QAVEAYVTHIESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLTSLLIELS
MMAR_0345|M.marinum_M QAVEAYVSHIESRLAVTLSWIREFPSLGPISYPVQRHGMNLLTSLLVELS
MUL_4775|M.ulcerans_Agy99 QAVEAYLSHIESRLAVTLSWIREFPSLGPISYPVQRHGMNLLTSLLVELS
MAV_5161|M.avium_104 QAVEAYVGYIEARPAITLSWIRELPSLGAAARPVQRRGLQLLTSLLIDLS
MSMEG_6480|M.smegmatis_MC2_155 QAVGAYVEHIESAPSITLSWIRELPALGPAARPLQRDAMGALTDLLIDLS
TH_0083|M.thermoresistible__bu QAVVAYVDHIESRPAITLAWIRELPAIGASVRPIQRAMMHELTELLIELS
MAB_1149|M.abscessus_ATCC_1997 QVALALLSYIEERTDGFRILIRDSP-PGVSSGTYSSLLNDAVSQVSSILA
:.. * : :*. **: * * . ::.: *:
Mflv_1103|M.gilvum_PYR-GCK GSSGFRRAGLQPIEPAIALILLGGLRELTALFVEDGRDMRGIAGPATAAA
Mvan_5713|M.vanbaalenii_PYR-1 GNPGFRRAGLDPITAPVALILVGGLRELTALFVEDERDVHGIAAPAVAAA
Mb0140c|M.bovis_AF2122/97 ASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIVEPAVDAS
Rv0135c|M.tuberculosis_H37Rv ASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIVEPAVDAS
MMAR_0345|M.marinum_M ASPGFRRAGLPAVPGALAVILLGGLRELTALTVEDGRDIREIVEPAVDAS
MUL_4775|M.ulcerans_Agy99 ASPGFRRAGLPAVPGALAVILLGGLRELTALTVEDGRDIREIVEPAVDAS
MAV_5161|M.avium_104 ASPGFRRAQLPPLTAPLAVILLGGLRELTALAVEDGKPVRGIVEPAVDAS
MSMEG_6480|M.smegmatis_MC2_155 DSPGFRRAGLNGLSRQMAIILLGGLRELTALIVEDGHDIREIYEPAVAAS
TH_0083|M.thermoresistible__bu RSPGFARAQMPPLTRQLAVFLLGGLRELTALFVEDGRDVRGLIAPAVSAS
MAB_1149|M.abscessus_ATCC_1997 G--DFQRRGLDAEMAPLYAQALVGQVSMTAQWWLDAREPKKEVVAAHIVN
.* * : : : * .:** * : : .* .
Mflv_1103|M.gilvum_PYR-GCK VALLGPH-----------
Mvan_5713|M.vanbaalenii_PYR-1 TALVSAG-----------
Mb0140c|M.bovis_AF2122/97 IALLGPRS----------
Rv0135c|M.tuberculosis_H37Rv IALLGPRS----------
MMAR_0345|M.marinum_M IALVGPRH----------
MUL_4775|M.ulcerans_Agy99 IALVGPRH----------
MAV_5161|M.avium_104 VALLGPRH----------
MSMEG_6480|M.smegmatis_MC2_155 RAILTASSAEHQAR----
TH_0083|M.thermoresistible__bu KALLSAGASE--------
MAB_1149|M.abscessus_ATCC_1997 LCWHGLKHLEADPQLHEE
.