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TAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTVSDIVRHARTSKRTFYDRFTSKEQCFLELLLADN ETLGNSIRAAVDPNADWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLTSLLIE LSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIVEPAVDASIALLGPRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0135c | - | - | 100% (201) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv0238 | - | 3e-07 | 24.52% (155) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 2e-05 | 30.67% (75) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0140c | - | 1e-110 | 100.00% (201) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1103 | - | 2e-59 | 61.88% (181) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 3e-06 | 25.90% (139) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1576 | - | 1e-06 | 26.88% (93) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0345 | - | 2e-83 | 78.50% (200) | transcriptional regulatory protein |
| M. avium 104 | MAV_5161 | - | 2e-81 | 78.84% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6480 | - | 1e-63 | 64.80% (196) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0083 | - | 1e-68 | 66.84% (196) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4775 | - | 3e-83 | 78.00% (200) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5713 | - | 7e-55 | 58.10% (179) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0135c|M.tuberculosis_H37Rv ------------MTAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTV
Mb0140c|M.bovis_AF2122/97 ------------MTAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTV
MMAR_0345|M.marinum_M ------------MTAAASSPAALDSDPFRQRLLEGLVASIGERGYHATTV
MUL_4775|M.ulcerans_Agy99 ------------MTAAASSPAALDSDPFRQRLLEGLVASIGERGYHATTV
MAV_5161|M.avium_104 ------------MTATDGEPDLGEIDPFRLRLLDGLATSIGERGYRASTV
Mflv_1103|M.gilvum_PYR-GCK ---------------------------MNDRLLDGLASSIVERGYRETTV
Mvan_5713|M.vanbaalenii_PYR-1 -------------MRTTPLAAGP-HPSVADRLLDGLASAITERGYRDSTV
MSMEG_6480|M.smegmatis_MC2_155 ---------MTTALTGTATAGGSGGDAFRSRLLDGLSTAIDDKGYRDSTV
TH_0083|M.thermoresistible__bu -----------MTTAVQPADVGAGDDAFRGRLLSGLAASIAERGYRETTV
MLBr_02568|M.leprae_Br4923 ---------------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSM
MAB_1576|M.abscessus_ATCC_1997 MTRPGAPLGKLMARAVRGLGSHPEPDDIETRLLDAAIEVLSERGTQTATI
::*.. : .* : :::
Rv0135c|M.tuberculosis_H37Rv SDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADW
Mb0140c|M.bovis_AF2122/97 SDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADW
MMAR_0345|M.marinum_M ADIVRHARTSKRTFYDRFESKEQCFLDLLRADNERLAKRIRAAVDPEADW
MUL_4775|M.ulcerans_Agy99 ADIVRHARTSKRTFYDRFESKEQCFLDLLRADNERLAKRIRAAVDPEADW
MAV_5161|M.avium_104 ADVVRCARTSKRTFYDHFAGKEECFLELLAVDIEKLGAKIAASVDPEADW
Mflv_1103|M.gilvum_PYR-GCK ADIVRHAKTSKRAFYEQFASKEQCLIELLRNNNTDLIAHINAAVDPESDW
Mvan_5713|M.vanbaalenii_PYR-1 ADVVRYARTSKRTFYEQFASKEECLIEMLRRNHSDLIAGIGAAVEPEADW
MSMEG_6480|M.smegmatis_MC2_155 ADIVRHARTSKRTFYDQFASKEACFIELLRANNAALVEHIRSAVSPEAEW
TH_0083|M.thermoresistible__bu ADIVRHARTSKRTFYDQFGSKEECFQELLWANNIDMIGAIRAAVDPEADW
MLBr_02568|M.leprae_Br4923 DAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSP
MAB_1576|M.abscessus_ATCC_1997 DEVARRAKVGRATVFRRFSSKDQLFERALAQEMRKFLDELQARAGEFDDI
:. *: .: .: : .*: : * : : : : .
Rv0135c|M.tuberculosis_H37Rv HDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAY--PVQRRGMEQLT
Mb0140c|M.bovis_AF2122/97 HDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAY--PVQRRGMEQLT
MMAR_0345|M.marinum_M QAQIRQAVEAYVSHIESRLAVTLSWIREFPSLGPISY--PVQRHGMNLLT
MUL_4775|M.ulcerans_Agy99 QAQIRQAVEAYLSHIESRLAVTLSWIREFPSLGPISY--PVQRHGMNLLT
MAV_5161|M.avium_104 HVQIRQAVEAYVGYIEARPAITLSWIRELPSLGAAAR--PVQRRGLQLLT
Mflv_1103|M.gilvum_PYR-GCK REQIGQAVDAYIGHISARPAITLCWIREAPALGAVAR--PLHRQVMRDLT
Mvan_5713|M.vanbaalenii_PYR-1 RLQIDKAVGAYIDHISARPAITLCWIREAPGLGAAAR--PLHRLVMGDLT
MSMEG_6480|M.smegmatis_MC2_155 QDQIDQAVGAYVEHIESAPSITLSWIRELPALGPAAR--PLQRDAMGALT
TH_0083|M.thermoresistible__bu SEQIRQAVVAYVDHIESRPAITLAWIRELPAIGASVR--PIQRAMMHELT
MLBr_02568|M.leprae_Br4923 KDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQ--TVR-EARDQIT
MAB_1576|M.abscessus_ATCC_1997 GERVAEGFAVCIEIVNHPLLRGDSLVARMTAVEAITQGDPAPIELARNYL
: : . : :. . .: . .
Rv0135c|M.tuberculosis_H37Rv SLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIV
Mb0140c|M.bovis_AF2122/97 SLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIV
MMAR_0345|M.marinum_M SLLVELSASPGFRRAGLPAVPGALAVILLGGLRELTALTVEDGRDIREIV
MUL_4775|M.ulcerans_Agy99 SLLVELSASPGFRRAGLPAVPGALAVILLGGLRELTALTVEDGRDIREIV
MAV_5161|M.avium_104 SLLIDLSASPGFRRAQLPPLTAPLAVILLGGLRELTALAVEDGKPVRGIV
Mflv_1103|M.gilvum_PYR-GCK EMLTALTGSSGFRRAGLQPIEPAIALILLGGLRELTALFVEDGRDMRGIA
Mvan_5713|M.vanbaalenii_PYR-1 DLLVSLTGNPGFRRAGLDPITAPVALILVGGLRELTALFVEDERDVHGIA
MSMEG_6480|M.smegmatis_MC2_155 DLLIDLSDSPGFRRAGLNGLSRQMAIILLGGLRELTALIVEDGHDIREIY
TH_0083|M.thermoresistible__bu ELLIELSRSPGFARAQMPPLTRQLAVFLLGGLRELTALFVEDGRDVRGLI
MLBr_02568|M.leprae_Br4923 ELVAGLMR-VGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAA
MAB_1576|M.abscessus_ATCC_1997 AAQIDQMREEGRIPPGDSRRQVDVLIHLVLGYLAAPATTIDLGNTEEVRA
* . : *: . .:
Rv0135c|M.tuberculosis_H37Rv EPAVDASIALLGPRS------------
Mb0140c|M.bovis_AF2122/97 EPAVDASIALLGPRS------------
MMAR_0345|M.marinum_M EPAVDASIALVGPRH------------
MUL_4775|M.ulcerans_Agy99 EPAVDASIALVGPRH------------
MAV_5161|M.avium_104 EPAVDASVALLGPRH------------
Mflv_1103|M.gilvum_PYR-GCK GPATAAAVALLGPH-------------
Mvan_5713|M.vanbaalenii_PYR-1 APAVAAATALVSAG-------------
MSMEG_6480|M.smegmatis_MC2_155 EPAVAASRAILTASSAEHQAR------
TH_0083|M.thermoresistible__bu APAVSASKALLSAGASE----------
MLBr_02568|M.leprae_Br4923 ELMINLFWHGLKGAPADRDFGPSIVAG
MAB_1576|M.abscessus_ATCC_1997 LARETFAPILLTPNVPLKAP-------
: