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M. thermoresistible (build 8) TH_2435 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 3131995 - 3132720
length: 242

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2435 - - 100% (242) short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_3102 - 1e-57 48.32% (238) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_0026 - 7e-46 52.90% (155) 3-oxoacyl-(acyl-carrier-protein) reductase, putative

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1519 fabG1 2e-35 36.93% (241) 3-oxoacyl-
M. gilvum PYR-GCK Mflv_1258 - 3e-98 73.75% (240) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv1483 fabG1 2e-35 36.93% (241) 3-oxoacyl-
M. leprae Br4923 MLBr_01807 fabG1 5e-37 36.21% (243) 3-oxoacyl-
M. abscessus ATCC 19977 MAB_2723c - 2e-34 34.87% (238) 3-oxoacyl-
M. marinum M MMAR_4715 - 2e-55 48.74% (238) 3-oxoacyl-
M. avium 104 MAV_1395 - 3e-90 65.42% (240) 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_0527 - 3e-99 72.92% (240) 2-hydroxycyclohexnecarboxyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_0315 fabG2 3e-56 49.58% (238) 3-oxoacyl-
M. vanbaalenii PYR-1 Mvan_4185 - 6e-70 52.92% (240) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1258|M.gilvum_PYR-GCK          ------------------MVSRVAVVTGGASGLGEAICAGLAADGHRVAV
MSMEG_0527|M.smegmatis_MC2_155      -------------------MSRVAAVTGAGSGVGRATALQLARDGHRVAV
TH_2435|M.thermoresistible__bu      -------------------------VTGGASGLGRAIAARLGDDGHRVAV
MAV_1395|M.avium_104                ----------------------MAVVTGGGSGIGRAIVERLAHDGHRVAV
Mvan_4185|M.vanbaalenii_PYR-1       -------------------MTRVAVVTGGASGMGEATCHELGRRGCKVAV
MMAR_4715|M.marinum_M               ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99           ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
Mb1519|M.bovis_AF2122/97            MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
Rv1483|M.tuberculosis_H37Rv         MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_2723c|M.abscessus_ATCC_199      MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAV
                                                             ***.  *:* *    *   *  **.

Mflv_1258|M.gilvum_PYR-GCK          LDLDADAANRVAASLRGNGASAVGVAVDVSDEDAVVRAFDAVRTEFGPVE
MSMEG_0527|M.smegmatis_MC2_155      MDLDGQAAEEAAAKIESHGGRALAVAVDVADESAVAAGFEAARQAFGPIG
TH_2435|M.thermoresistible__bu      LDIDHAAAEQTAAELRAHGGDAVAVGADVADQDAVHDAFAAIRGSLGPVH
MAV_1395|M.avium_104                LDVNEEAAEKVAARVAADGAHAIAVPTDVAESASVAAAFESVRRALGSVQ
Mvan_4185|M.vanbaalenii_PYR-1       LDLDGQAAQRVAEELRGDGVPALGVAADVTDRAAVEDAFAKVRTELGPVH
MMAR_4715|M.marinum_M               LDLKTPDGE-------------LAFSADVTNRSQVDAALTAIRQRLGPVT
MUL_0315|M.ulcerans_Agy99           LDLKTPDGG-------------LAFSADVTNRSQVDAALAAIRQRLGPVT
Mb1519|M.bovis_AF2122/97            THRGSGAPKG-----------LFGVECDVTDSDAVDRAFTAVEEHQGPVE
Rv1483|M.tuberculosis_H37Rv         THRGSGAPKG-----------LFGVECDVTDSDAVDRAFTAVEEHQGPVE
MLBr_01807|M.leprae_Br4923          THRASVVPDW-----------FFGVECDVTDNDAIGAAFKAVEEHQGPVE
MAB_2723c|M.abscessus_ATCC_199      THRGSGAPEG-----------LLGVQCDITDNDQIDAAFKEVEEKQGPVE
                                     .                    ...  *:::   :  .:   .   *.: 

Mflv_1258|M.gilvum_PYR-GCK          ILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRAALSDMVAAQWG
MSMEG_0527|M.smegmatis_MC2_155      IVVTSAAMGGFTRFDKITLDEWNRYLAVNLTGTFLCIRAALPDMVKAQWG
TH_2435|M.thermoresistible__bu      ILVTSAAIAGFTRFDEITLDEWNRYLAVNLTGTFLCVQAALTDMVADGWG
MAV_1395|M.avium_104                VLVTSAAITGFKPFAEITIEDWNRHLAVNLTGTFLCLQAALPDMVEAGWG
Mvan_4185|M.vanbaalenii_PYR-1       ILVTSAGLVDFAPFLEISPDRWQRLIEVNLNGTFHCAQVAIPDMLAAGWG
MMAR_4715|M.marinum_M               ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
MUL_0315|M.ulcerans_Agy99           ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
Mb1519|M.bovis_AF2122/97            VLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFG
Rv1483|M.tuberculosis_H37Rv         VLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFG
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
MAB_2723c|M.abscessus_ATCC_199      VLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFG
                                    ::*  *.:     : .:: : : : : .** *.*   : .  .*    :*

Mflv_1258|M.gilvum_PYR-GCK          RVVTISSAAGQQGAPRQGHYSATKGGVIAMTKTVARDYARHGITANSLPP
MSMEG_0527|M.smegmatis_MC2_155      RIVTISSAAGQRGAPAQGHYSATKGGVIAMTKTLALDYAAKGITANTIPP
TH_2435|M.thermoresistible__bu      RIVTISSAAGQQGAHRQGHYAATKGGVIALTKTVALDYAAKGITANTVPP
MAV_1395|M.avium_104                RVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAAHGITANTVPP
Mvan_4185|M.vanbaalenii_PYR-1       RIVMISSSSAQRGSPGMAHYAASKGALISFTRSLAREYGPAGITVNNVPP
MMAR_4715|M.marinum_M               RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
MUL_0315|M.ulcerans_Agy99           RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
Mb1519|M.bovis_AF2122/97            RMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP
Rv1483|M.tuberculosis_H37Rv         RMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP
MLBr_01807|M.leprae_Br4923          RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP
MAB_2723c|M.abscessus_ATCC_199      RLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAP
                                    * : :.*     *     :* *:*..: .:::::: : .  .:*.* :.*

Mflv_1258|M.gilvum_PYR-GCK          FAIETPMLRRQQSEGKLPPDEFLTQAIPAGRVGAPSDVAAVCSFLCSDAA
MSMEG_0527|M.smegmatis_MC2_155      FVIDTPMLREQQAAGLLPQAEHLTKAIPAGRLGSGDDVAAMCSFLCSDAA
TH_2435|M.thermoresistible__bu      FVIDSPMLREQQRRGTLPPAEYLTRAIPMGRLGVAEDVAAVCSFLCSDAA
MAV_1395|M.avium_104                FSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACAFLCSDEA
Mvan_4185|M.vanbaalenii_PYR-1       SGIETPMQHQSQAAGFLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSEEA
MMAR_4715|M.marinum_M               GFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEA
MUL_0315|M.ulcerans_Agy99           GFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEA
Mb1519|M.bovis_AF2122/97            GYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDA
Rv1483|M.tuberculosis_H37Rv         GYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDA
MLBr_01807|M.leprae_Br4923          GFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
MAB_2723c|M.abscessus_ATCC_199      GFIDTDMTRELGEK----HVETALTAIPMGRIGEPSEVAGVVSWLASPDA
                                      ::: * :           :      *  ::*   ::*.  .:* *  *

Mflv_1258|M.gilvum_PYR-GCK          GYVTGQVIGVNGGAVL--
MSMEG_0527|M.smegmatis_MC2_155      GYVTGQVIGVNGGAVL--
TH_2435|M.thermoresistible__bu      GYLTGQVIGVNGGAIR--
MAV_1395|M.avium_104                GYITGQIIGVNGGEVI--
Mvan_4185|M.vanbaalenii_PYR-1       GFITGQTLGVNGGSVMA-
MMAR_4715|M.marinum_M               GYITGQILGVNGGRNT--
MUL_0315|M.ulcerans_Agy99           GYITGQILGVNGGRNT--
Mb1519|M.bovis_AF2122/97            SYISGAVIPVDGGMGMGH
Rv1483|M.tuberculosis_H37Rv         SYISGAVIPVDGGMGMGH
MLBr_01807|M.leprae_Br4923          GYISGAVIPVDGGLGMGH
MAB_2723c|M.abscessus_ATCC_199      AYVSGAVIPVDGGLGMGH
                                    .:::*  : *:**

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2435	-	-	100% (242)	short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_3102	-	1e-57	48.32% (238)	PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_0026	-	7e-46	52.90% (155)	3-oxoacyl-(acyl-carrier-protein) reductase, putative