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M. gilvum PYR-GCK Mflv_1180 (-)

annotation: hypothetical protein Mflv_1180
coordinates: 1238560 - 1240119
length: 519

FDNLVPEPAALAGLSDAELVDAAGAAARAENAVCARKLAVMAELFTRRVDLAPEDRLNWWVDPDAAVAAE
IAAAVTITQGLATHQTYRAVVLRDRLPKVGALFLAGLLSELLVRAIITRTDLITDPELIAAVDADLAADI
LRWGPQSAKKTEAAIDHIVERHDPDAVRQSRAGDLDRAIEIGNPGDAPGYTTVWARMFAGDAAAGQRTLT
AMAYSVCDNDPRTLDERRNDALTALFHGITTLACRCGHTDCDAATNPRPPRELTVYALTDQTTADSASEE
PRGDATDADASAGDAQPATPTAPKPRRSKPTLLPGRSGYLFGSGFMSAPLFDALLDGAKIREIIHPGQAG
PEPRYTPSTALADFIRCRDLTCRFPGCDTPATEADIDHTVAHPVGPTHASNLKCLCRFHHLLKTFWTGPG
GWHDRQHPDGTITWTSPTGHTYITHPGSRLLFPTLCKPTATLWTGNPPQNPTNNNRGSMMPRRTRTRAQN
RATYITAERTRNAAHRTDSPRGNDPPPF*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1180--100% (519)hypothetical protein Mflv_1180
M. gilvum PYR-GCKMflv_4099-0.093.23% (517) hypothetical protein Mflv_4099
M. gilvum PYR-GCKMflv_0179-0.088.78% (526) hypothetical protein Mflv_0179

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2126-1e-11144.30% (535) hypothetical protein Mb2126
M. tuberculosis H37RvRv2100-1e-11144.30% (535) hypothetical protein Rv2100
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4752-5e-7136.22% (508) hypothetical protein MAB_4752
M. marinum MMMAR_5187-1e-10242.97% (498) 13e12 repeat-containing protein
M. avium 104MAV_4456-1e-10141.12% (535) 13e12 repeat-containing protein
M. smegmatis MC2 155MSMEG_0144-1e-11741.83% (600) HNH endonuclease
M. thermoresistible (build 8)TH_0334-7e-6737.63% (396) HNH endonuclease
M. ulcerans Agy99MUL_2679-1e-8139.92% (471) 13e12 repeat-containing protein
M. vanbaalenii PYR-1Mvan_0728-0.075.48% (518) hypothetical protein Mvan_0728

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_5187|M.marinum_M               ------------------------MFESMGVAAGVDHPCDALAERRQLRT
MAV_4456|M.avium_104                ------------------------------MCEDATAWFDELMER-CYPS
MUL_2679|M.ulcerans_Agy99           --------------------------------------MDQHIIEYVFDT
TH_0334|M.thermoresistible__bu      ----------------------------------------------MFES
MAB_4752|M.abscessus_ATCC_1997      ----------------------------------------------MFDE
Mflv_1180|M.gilvum_PYR-GCK          --------------------------------------MFDNLVPEPAAL
Mvan_0728|M.vanbaalenii_PYR-1       --------------------------------------MFDVLVPDPADL
MSMEG_0144|M.smegmatis_MC2_155      ---MSWGYPQTRVHPQIAVLRCRG-----GFTVGRFERMYEGLLVQIAEF
Mb2126|M.bovis_AF2122/97            MAGALFEPSFAAAHPAGLLRRPVTRTVVLSVAATSIAHMFEISLPDPTEL
Rv2100|M.tuberculosis_H37Rv         MAGALFEPSFAAAHPAGLLRRPVTRTVVLSVAATSIAHMFEISLPDPTEL
                                                                                      

MMAR_5187|M.marinum_M               PTAESARWVQRIGAAARAENRAAAAQLIEIGQLFAYRLSR--CSETEDWA
MAV_4456|M.avium_104                ATPESAALVQRIGVFARVENRAAAEQLAAIGELFAYRLSR--CSECEDWA
MUL_2679|M.ulcerans_Agy99           ---DDSAPLTRITAAARAEARAAAERLAAIGDLFRLRLSQ--HGNREDWV
TH_0334|M.thermoresistible__bu      --LDDGAVVDSIAAASREQSAACGREMLAIGELYARRAPED-DTERANWA
MAB_4752|M.abscessus_ATCC_1997      --LGDVELIDLIASAQRAEAQACARKLDAIGVLVDRHADLGKPDERDHHA
Mflv_1180|M.gilvum_PYR-GCK          AGLSDAELVDAAGAAARAENAVCARKLAVMAELFTRRVDLAPED-RLNWW
Mvan_0728|M.vanbaalenii_PYR-1       AALSDAELLDAATATTRAENAVCARKLAVMAELFIRRTTLAPQD-RLDWW
MSMEG_0144|M.smegmatis_MC2_155      SALSDLELEGQARGWAQAEASASAHKHAAMAELFIRATSTPSADERRWWF
Mb2126|M.bovis_AF2122/97            CRSDDGALVAAIEDCARVEAAASARRLSAIAELTGRRTG---ADQRADWA
Rv2100|M.tuberculosis_H37Rv         CRSDDGALVAAIEDCARVEAAASARRLSAIAELTGRRTG---ADQRADWA
                                        .           : :  ... .   :. *                 

MMAR_5187|M.marinum_M               VDTMEAVAAEVAAGLRISQGLAASRLRYARALRERLPKTGAVFAAGQIDL
MAV_4456|M.avium_104                VDTEAAVSAEVAAQLRIGQGLAAAKVRYARAMRERLPRVGEVFRAGEIDF
MUL_2679|M.ulcerans_Agy99           ADTCDAVAAEVAAALNTSVAMGHSNLRYARAMRERLPQLGAEFRAGGIDF
TH_0334|M.thermoresistible__bu      IDGHANVVAEISAALNISRGRAAGRLQLAIDLRERLPRVAAVFAAGDIDF
MAB_4752|M.abscessus_ATCC_1997      LDRWDRVASEVAAAQGITHALASSQMRYAQVLRHRLRAVAERFAAGDLDF
Mflv_1180|M.gilvum_PYR-GCK          VDPDAAVAAEIAAAVTITQGLATHQTYRAVVLRDRLPKVGALFLAGLLSE
Mvan_0728|M.vanbaalenii_PYR-1       VDPEAAVTAELAAAHHITQGLATHQAYRAVVLRDRLPKIGALFLQGLLSE
MSMEG_0144|M.smegmatis_MC2_155      VDPDAAVGAQLGAAQGITAWAALHQAQRGVALRDRLPKVNEVFAAGLVSE
Mb2126|M.bovis_AF2122/97            CDFWDCAAAEVAAALTISHGKASGQMHLSLALN-RLPQVAALFLAGHLGA
Rv2100|M.tuberculosis_H37Rv         CDFWDCAAAEVAAALTISHGKASGQMHLSLALN-RLPQVAALFLAGHLGA
                                     *    . :::.*        .  .   .  :. **      *  * :. 

MMAR_5187|M.marinum_M               RAFQTIVFRTDLIVDPQVMAAVDALVALNVGRWPSMTKARLSGQIDAIVA
MAV_4456|M.avium_104                RLFATIVYRTDLITDRRVLAAVDAELAATAARWPSMTRARLAARVDAVVA
MUL_2679|M.ulcerans_Agy99           RLFRTIVFRTDLITESDALAAVDARLAIKAPRWPSMTSWKLATEVDRVVA
TH_0334|M.thermoresistible__bu      RMVSALVNRSRNVVDPDLLARLDAALAAWSPKWMKLSGPTLNERIDMWVE
MAB_4752|M.abscessus_ATCC_1997      RTVALIINRTELVDDEAVVARVDAAIVRALPRWARWSHKRITAALDALVL
Mflv_1180|M.gilvum_PYR-GCK          LLVRAIITRTDLITDPELIAAVDADLAADILRWGPQSAKKTEAAIDHIVE
Mvan_0728|M.vanbaalenii_PYR-1       LLVRAIITRTGLITDPDLIAAVDADLATDILDWGPLSVKATEAEIDAIID
MSMEG_0144|M.smegmatis_MC2_155      MIVRNICWSTALMLEPDKLALIDAELAAQISGWGKLTLKEIDNTIDDLIL
Mb2126|M.bovis_AF2122/97            RLFSIIAWRTYLVRDPHALSLLDAALAEHAGAWGPLSAPKLEKAIDSWID
Rv2100|M.tuberculosis_H37Rv         RLFSIIAWRTYLVRDPHALSLLDAALAEHAGAWGPLSAPKLEKAIDSWID
                                      .  :   :  : :   :: :** :.     *   :       :*  : 

MMAR_5187|M.marinum_M               RADADAVRRRKERHADREIWIGQDADG--ISRIDGSMFTIDAHALDRRLS
MAV_4456|M.avium_104                KADADAVRRTEKQAASRHVWIAEMGEG--LSHLEGTVSSPDAHALDKRLD
MUL_2679|M.ulcerans_Agy99           KFDRDAVRRSRRDAADRYVDCAPLEPG--MALVNRQVFSATAEALARRLD
TH_0334|M.thermoresistible__bu      RFDPTGVREPRSPGEDRYVVVTPAGQG--MVDVSARLTFEAGFAFXTRLD
MAB_4752|M.abscessus_ATCC_1997      HFDQDAVRRNRSATDKRHLEIRPLGNGEPVAEVWGTLQAVHAVALDKRLD
Mflv_1180|M.gilvum_PYR-GCK          RHDPDAVRQSRAGDLDRAIEIGNPGDAPGYTTVWARMFAGDAAAGQRTLT
Mvan_0728|M.vanbaalenii_PYR-1       RHDPDAVRKSRAPETGRTVQFGNPGDAPGYTSMWARMYASDAAAADRTLT
MSMEG_0144|M.smegmatis_MC2_155      KHDPGSFRRGRASRRGRYFDIGSPTDAPGVLTVTGRLQAHLGNAYDARIA
Mb2126|M.bovis_AF2122/97            RYDPGALRRSRISARTRDLCIGDPDEDAGTAALWGRLYATDAAMLDRRLT
Rv2100|M.tuberculosis_H37Rv         RYDPGALRRSRISARTRDLCIGDPDEDAGTAALWGRLYATDAAMLDRRLT
                                    : *  ..*. .     * .             :   :    .      : 

MMAR_5187|M.marinum_M               ALAATVCAQDPRSREQRRADALGVLAAGGDRLGCRCGLPDC-AAGARPAA
MAV_4456|M.avium_104                ALAATVCEHDPRTGEQRRADALGALAAGADRLGCRCGRADC-AAGTRPAA
MUL_2679|M.ulcerans_Agy99           ELAKTVCADDPRTVVQRRADALGTLAAGQDRLICDCGRTDCPAAGAPQQP
TH_0334|M.thermoresistible__bu      QIAATVCRDDPRTADQRRADAMAAMSEGQNRLVCGCGSEDCPADPADTAA
MAB_4752|M.abscessus_ATCC_1997      LLAGTVCPADPRSKTQRRADAVGALTQGLNRMRCACGHPDC--SGRDTAD
Mflv_1180|M.gilvum_PYR-GCK          AMAYSVCDNDPRTLDERRNDALTALFHGITTLACRCGHTDCDAAT-NPRP
Mvan_0728|M.vanbaalenii_PYR-1       ALAYSVCDNDPRTLDERRNDAHTALLTGITTLACQCGNPDCHAST-NPRP
MSMEG_0144|M.smegmatis_MC2_155      ELIEGVCPDDPRTLNELRHDALGAILD-HTTLACECEDPDCVRGR-EQSP
Mb2126|M.bovis_AF2122/97            EMAHGVCEDDPRTLAQRRADALGALAAGADHLACGCGKPDCPSGAGNDER
Rv2100|M.tuberculosis_H37Rv         EMAHGVCEDDPRTLAQRRADALGALAAGADHLACGCGKPDCPSGAGNDER
                                     :   **  ***:  : * **  .:      : * *   **         

MMAR_5187|M.marinum_M               QP-VVIHVIAERATLDGDGG------------------------------
MAV_4456|M.avium_104                GP-VVIHLIAERASVEGTGG------------------------------
MUL_2679|M.ulcerans_Agy99           SR-VVIHVVAGCQTVDGAGE------------------------------
TH_0334|M.thermoresistible__bu      TR-LVINVIAEQATVEGRSD------------------------------
MAB_4752|M.abscessus_ATCC_1997      VP-VVVNVVINQSTLAGSDD------------------------------
Mflv_1180|M.gilvum_PYR-GCK          PRELTVYALTDQTTADSASEEPRG----DATDADASAGDAQPATPTAPKP
Mvan_0728|M.vanbaalenii_PYR-1       PRDITVYALTDHTTTT------------DTGDADTTT-DTKPPTPPAPQP
MSMEG_0144|M.smegmatis_MC2_155      RGHLVVHVIAREDTVTAAQHAATTTNTPDDAPADTPAADTEPAEPAEPAE
Mb2126|M.bovis_AF2122/97            AAGVVIHVVADASALDAQPDPHLSG---DEPPSRPLTPETTLFEALTPDP
Rv2100|M.tuberculosis_H37Rv         AAGVVIHVVADASALDAQPDPHLSG---DEPPSRPLTPETTLFEALTPDP
                                       :.:  :    :                                    

MMAR_5187|M.marinum_M               ---------------------APAWEVGA---------------------
MAV_4456|M.avium_104                ---------------------GPAVEVGA---------------------
MUL_2679|M.ulcerans_Agy99           ---------------------APGVLPG----------------------
TH_0334|M.thermoresistible__bu      ---------------------NPGYLPG----------------------
MAB_4752|M.abscessus_ATCC_1997      ---------------------CPAHVPG----------------------
Mflv_1180|M.gilvum_PYR-GCK          RRS------------------KPTLLPGR---------------------
Mvan_0728|M.vanbaalenii_PYR-1       RRS------------------KPILIPGR---------------------
MSMEG_0144|M.smegmatis_MC2_155      PAEPAEPAEPAEPAEPVEPVDDPDIAPAASATETATDTTASPTGTDCDPE
Mb2126|M.bovis_AF2122/97            EPDP-----------------PATHAPAE---------------------
Rv2100|M.tuberculosis_H37Rv         EPDP-----------------PATHAPAE---------------------
                                                          .    .                      

MMAR_5187|M.marinum_M               ------------------------------------DGLVTPELVAELAK
MAV_4456|M.avium_104                ------------------------------------EGLLPAQLVAELAA
MUL_2679|M.ulcerans_Agy99           ------------------------------------DGIIPAEIVRELAK
TH_0334|M.thermoresistible__bu      ------------------------------------YGAVPASILRAKAA
MAB_4752|M.abscessus_ATCC_1997      ------------------------------------FGVLAAESARAAVA
Mflv_1180|M.gilvum_PYR-GCK          ------------------------------SGYLFGSGFMSAPLFDALLD
Mvan_0728|M.vanbaalenii_PYR-1       ------------------------------PAYLFGAGFMPAPLFDALLA
MSMEG_0144|M.smegmatis_MC2_155      SVSVTEFTDNSSDTPSAFLDPDEHPLDRVPPAVLFGGGVLPAYALAEIIN
Mb2126|M.bovis_AF2122/97            -------------------------------LITTGGGVVPAPLLAELIR
Rv2100|M.tuberculosis_H37Rv         -------------------------------LITTGGGVVPAPLLAELIR
                                                                         * :..        

MMAR_5187|M.marinum_M               S-AKLVPLRHPG-DVPPEPGYVPSKALADFVRCRDLTCRWPGCDHPALNC
MAV_4456|M.avium_104                S-ARLMPLVHPA-DAPPENRYTPSAALADFVRCRDLTCRWPGCDRPATEC
MUL_2679|M.ulcerans_Agy99           S-AKLQPMSTP---ILAETGYVPSPALMDFVRARDLTCRAPGCDRPATQC
TH_0334|M.thermoresistible__bu      T-ATLRPVALP--QPCAEAGYRPSAALTRFIRCRDLTCRFPGCDAPAAVC
MAB_4752|M.abscessus_ATCC_1997      G-TPTRNLTDS-----RSTGYRPSAKLAAFVRSRDQLCRFPGCEAVADRA
Mflv_1180|M.gilvum_PYR-GCK          G-AKIREIIHPG-QAGPEPRYTPSTALADFIRCRDLTCRFPGCDTPATEA
Mvan_0728|M.vanbaalenii_PYR-1       E-ATIREIIHPGNRSAPEPRYTPSQALAEFIRCRDLTCRFPGCDKPATEA
MSMEG_0144|M.smegmatis_MC2_155      N-ATIRPLKHPG-DTAPEDRYIPSRALADYVRCRDLTCRFPGCDKPADRC
Mb2126|M.bovis_AF2122/97            GGATISQVRHPG-DLAAEPHYRPSAKLAEFVRMRDLTCRFPGCDVPAEFC
Rv2100|M.tuberculosis_H37Rv         GGATISQVRHPG-DLAAEPHYRPSAKLAEFVRMRDLTCRFPGCDVPAEFC
                                      :    :  .      .  * **  *  ::* **  ** ***:  *  .

MMAR_5187|M.marinum_M               DLDHTIPYAQGGPTHASNLKCYCRTHHLVKTFWG----WHDQQLPDGTLI
MAV_4456|M.avium_104                DLDHTIPYAEGGPTHASNLKCYCRTHHLVKTFWG----WREQQLPDATLI
MUL_2679|M.ulcerans_Agy99           DVDHTIPYSDGGATHPSNLKCLCRKHHLLKTFWG----WHDEQLPDATVI
TH_0334|M.thermoresistible__bu      QIDHTIPYPAG-PTHPSNLKLLCVFHCRQAELRF----THDQHKHQSSCL
MAB_4752|M.abscessus_ATCC_1997      DIDHTVPWATGGPTTGANLKALCRKHHLLKTFGQ----WTELQEPDGTVI
Mflv_1180|M.gilvum_PYR-GCK          DIDHTVAHPVG-PTHASNLKCLCRFHHLLKTFWTGPGGWHDRQHPDGTIT
Mvan_0728|M.vanbaalenii_PYR-1       DIDHTVPYPIG-PTHPSNLKCLCRFHHLLKTFWLGATGWHDRQHPDGTIT
MSMEG_0144|M.smegmatis_MC2_155      DLDHTVPYPAG-PTHASNLKCLCRFHHLLKTFWTGPRGWTDRQHPDGTIV
Mb2126|M.bovis_AF2122/97            DIDHSAPWPLG-PTHPSNLKCACRKHHLLKTFWTG---WRDVQLPDGTVI
Rv2100|M.tuberculosis_H37Rv         DIDHSAPWPLG-PTHPSNLKCACRKHHLLKTFWTG---WRDVQLPDGTVI
                                    ::**: . . * .*  :***  *  *     :        : :  :.:  

MMAR_5187|M.marinum_M               LTSPAGHTYVTTPGSA--LLFPSLCHSTGGLPAAEADPPSDHCDQRSAMM
MAV_4456|M.avium_104                LTSPAGRTYVTTPGSA--LLFPSLCVPTG-EPARPVAAGSQPCGERTAMM
MUL_2679|M.ulcerans_Agy99           WSLPDGQTYVTTPGSA--WLLPGLFAPSPELPPP----------------
TH_0334|M.thermoresistible__bu      P------AYFQRPHG-----------------------------------
MAB_4752|M.abscessus_ATCC_1997      WKSPTGHRYATTPVSW--FLFPAL--------------------------
Mflv_1180|M.gilvum_PYR-GCK          WTSPTGHTYITHPGS--RLLFPTLCKPTATL-WTGNPPQNPTNNNRGSMM
Mvan_0728|M.vanbaalenii_PYR-1       WTAPTGHTYTTHPGS--RLLFPTLCQPTATL-WTGEPPQVPQSQQRGAMM
MSMEG_0144|M.smegmatis_MC2_155      WTSPSGRQYTTVPGSHRRLSITELAAPTGALDLPATPIPTADPDLRGVKM
Mb2126|M.bovis_AF2122/97            WTAPNGHTYTTHPGS--RIFFPTWHTTTAEL--PQTSTAAVNVDARGLMM
Rv2100|M.tuberculosis_H37Rv         WTAPNGHTYTTHPGS--RIFFPTWHTTTAEL--PQTSTAAVNVDARGLMM
                                            *   * .                                   

MMAR_5187|M.marinum_M               PRRQRTRAQDRARRVATERRQNHHARSTQPGGQPR---------------
MAV_4456|M.avium_104                PTRRRTRGQNRAARVAAERRANRAARLARATRPAP---------------
MUL_2679|M.ulcerans_Agy99           PRSEATGSLRKPRRDDAQTRPNSRPKLGR---------------------
TH_0334|M.thermoresistible__bu      PATRRPPSARGLREAVPRQGVDPRRVSGQ---------------------
MAB_4752|M.abscessus_ATCC_1997      -TRHHTRQQARDRRRRTERNLNREQRLQREAALAA---------------
Mflv_1180|M.gilvum_PYR-GCK          PRRTRTRAQNRATYITAERTRNAAHRTDS--------PR-----------
Mvan_0728|M.vanbaalenii_PYR-1       PRRRNTRAHNHAAYITAERRRNAQTRYATTGNTPPYLPRDHIPYQSSTGW
MSMEG_0144|M.smegmatis_MC2_155      PKRRRTRAQNTARTIAAERKLNDDLVAEH---------------------
Mb2126|M.bovis_AF2122/97            PRRRRTRAAELAHRINAERALNDAYMAER---------------------
Rv2100|M.tuberculosis_H37Rv         PRRRRTRAAELAHRINAERALNDAYMAER---------------------
                                         .          ..   :                            

MMAR_5187|M.marinum_M               ---SAAPPTPPQSEPQSHPPPF
MAV_4456|M.avium_104                ---AASQSWPAGHGPDADPPPF
MUL_2679|M.ulcerans_Agy99           ---THCDRTQPQHD--------
TH_0334|M.thermoresistible__bu      ----------------------
MAB_4752|M.abscessus_ATCC_1997      ---LAAKDPPPF----------
Mflv_1180|M.gilvum_PYR-GCK          -----GNDPPPF----------
Mvan_0728|M.vanbaalenii_PYR-1       REPDYGNDPPPF----------
MSMEG_0144|M.smegmatis_MC2_155      ------NKPPPF----------
Mb2126|M.bovis_AF2122/97            ------NKPPSF----------
Rv2100|M.tuberculosis_H37Rv         ------NKPPSF----------