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VSGGLPPLSVDPTQLSAAGGALKSSALDLPEAPAPFMPVGTDPLSVAIIGQIPAIETPIATQLPLIKAEA TTTASNVEDAAQAYAATDEQNSAAIDQVMQKTPSQMPSGSGGSAPGGGADAAGQMSQMMGMPMQMAQMPM QMMSGIASAPQGLMQGAQQASQQVQQMAGQFGQGATGGSASSAAQVPAPDAPAPEPASEGAAAGEPDAER APTPDERSDREDTGAPGRHRAAEADDRIDL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0763 | - | - | 100% (241) | hypothetical protein Mflv_0763 |
| M. gilvum PYR-GCK | Mflv_2182 | - | 2e-10 | 26.19% (252) | hypothetical protein Mflv_2182 |
| M. gilvum PYR-GCK | Mflv_1703 | - | 7e-07 | 28.33% (240) | transglycosylase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3908 | - | 4e-22 | 33.47% (248) | hypothetical protein Mb3908 |
| M. tuberculosis H37Rv | Rv3878 | - | 4e-22 | 33.47% (248) | hypothetical protein Rv3878 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1945c | - | 2e-06 | 25.56% (223) | dihydrolipoamide succinyltransferase |
| M. marinum M | MMAR_5453 | - | 8e-15 | 26.94% (245) | hypothetical protein MMAR_5453 |
| M. avium 104 | MAV_2415 | - | 1e-05 | 26.67% (285) | hypothetical protein MAV_2415 |
| M. smegmatis MC2 155 | MSMEG_0069 | - | 9e-22 | 32.90% (231) | translation initiation factor IF-2 protein |
| M. thermoresistible (build 8) | TH_2875 | - | 3e-18 | 33.05% (233) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4594 | - | 2e-13 | 30.51% (236) | hypothetical protein MUL_4594 |
| M. vanbaalenii PYR-1 | Mvan_0082 | - | 4e-76 | 60.98% (246) | hypothetical protein Mvan_0082 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 MAPLAVDPEAMYAAGSAVAAIGDSLAANLTILTAGVSAHTGVDRAGEVFG
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 LGYQDSAESMLKAAAGVVNACRKCGALIQQGASNYSAAEAASTLGGGSGA
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 LPAPSAPADLAAPGPPGTWGKGEPPPLLWAVIQALVSEVWPDGDEAGLHA
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 AASRWHGFAAAMNGVQGTLNASKALFDSQQIPEGEKIDHALAEIGAAAAA
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 IGQQCDALARTVDEFADRVGHAQQAIRDLLHRIEALGDIGHDIMLIIDGD
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 AWDEIQKIARDVNAVLQHLGQEARAFEQEIRLLMQAADREIVTCQKYARR
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 GLITFLGEDVGNPVATALDFGINVQEGVVKGAVGMGLGLVDLSPHWIALD
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 PEGAGATWGGLVKNAWKESFVNAAVNPQEFAQARLQELKGLVHADDWTRD
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 RPGLGAGEVAFDAATLIAPGLGEAGAAADGASAAARGAEAEADAAGAAGR
MAB_1945c|M.abscessus_ATCC_199 --------------------------------------------MAFSVQ
Mflv_0763|M.gilvum_PYR-GCK ------------------------------MVSGGLPPLSVDPTQLSAAG
Mvan_0082|M.vanbaalenii_PYR-1 ------------------------------MATGGTPPLSVDPEELSAAG
Mb3908|M.bovis_AF2122/97 ----------------------------------MAEPLAVDPTGLSAAA
Rv3878|M.tuberculosis_H37Rv ----------------------------------MAEPLAVDPTGLSAAA
MMAR_5453|M.marinum_M ----------------------------------MAEPLAVDPARLIAAG
MUL_4594|M.ulcerans_Agy99 ----------------------------------MAEPLAVDPAGLGAVG
TH_2875|M.thermoresistible__bu -------------------------------------LTAAISERITEVV
MSMEG_0069|M.smegmatis_MC2_155 ---------------------------------------------MEASA
MAV_2415|M.avium_104 VGGIAGARGALTDIAKSTADLPKNLEGVTKDLPEIKPPTGGAPVGLGPGG
MAB_1945c|M.abscessus_ATCC_199 MPALGESVTEGTVTRWLKQEGDTVEVDEPLLEVSTDKVDTEIPAPTSGVL
Mflv_0763|M.gilvum_PYR-GCK GALKSSALDLPEAPA--PFMPVGTDPLSVAIIGQIPAIETPIATQLPLIK
Mvan_0082|M.vanbaalenii_PYR-1 GALLDSARELPQAPA--PFNPVGTDPLSAAIIGQIPAVEAPIATQLPLIQ
Mb3908|M.bovis_AF2122/97 AKLAG--LVFPQPPA--PIAVSGTDSVVAAINKTMPSIESLVSDGLPGVK
Rv3878|M.tuberculosis_H37Rv AKLAG--LVFPQPPA--PIAVSGTDSVVAAINETMPSIESLVSDGLPGVK
MMAR_5453|M.marinum_M SKLAE--LVFPAPPA--PIAATGGDPVSAAINDTMPGIESLVSDGMPGVT
MUL_4594|M.ulcerans_Agy99 TRLRG--LVFPTPPA--LIVAAGTDALSVAINTAMPNIESSVTDLLPSAK
TH_2875|M.thermoresistible__bu DPVIE---ALPVTKE--ELKQFAQN--VVSAADEYDAKDRQIAEEILKQI
MSMEG_0069|M.smegmatis_MC2_155 R-------AIPEPPD--PFKTEGTDPLSKALADKTWQVEAPFIEGIGKTK
MAV_2415|M.avium_104 KPIEAPVESAPRPPDGTPGAQRGSPPVATSPASPGPAGDSGAGPHGPSSS
MAB_1945c|M.abscessus_ATCC_199 TKIVAREDDTVEIGGELGVISEAGEAAPAAPAPAPAPAAAPAPEPTPAPA
. :
Mflv_0763|M.gilvum_PYR-GCK AEATTTASN-------VEDAAQAYAATDEQNSAAIDQVMQKTPSQMPSGS
Mvan_0082|M.vanbaalenii_PYR-1 AQATSTAQN-------VVSAAQVYAETDARNGAAIHEQMQSRLDPLGTGS
Mb3908|M.bovis_AF2122/97 AALTRTASN-------MNAAADVYAKTDQSLGTSLSQYAFGSSGEGLAGV
Rv3878|M.tuberculosis_H37Rv AALTRTASN-------MNAAADVYAKTDQSLGTSLSQYAFGSSGEGLAGV
MMAR_5453|M.marinum_M AALKRTASS-------MSTAADIYAKADQALGDALTQYQFGGDGQALGAS
MUL_4594|M.ulcerans_Agy99 ADMANTASS-------MATAADIYTKVDESLGENLSQHQFRGSAPILTGS
TH_2875|M.thermoresistible__bu GAFDEPPAH-------GGAVPSGGSSAVTGPSSPLSAAGASVGGMTGASV
MSMEG_0069|M.smegmatis_MC2_155 AEAQETARR-------IQEAADKYEQSDRTIAENLQSSTGRFDASTGTEG
MAV_2415|M.avium_104 PAPAAPPGGPVGPHDPAPAPAPAASPGGPGGSGGVHDPAPAPAPAPAASG
MAB_1945c|M.abscessus_ATCC_199 PEATATAAP-------EPAAEPPAAAAPAGSGTSVKMPELGESVTEGTVT
.. . :
Mflv_0763|M.gilvum_PYR-GCK GG----SAPGGGADAAGQMS------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 GGGSLPSTAGGGADSLGMPM------------------------------
Mb3908|M.bovis_AF2122/97 ---ASVGGQPSQATQLLSTP------------------------------
Rv3878|M.tuberculosis_H37Rv ---ASVGGQPSQATQLLSTP------------------------------
MMAR_5453|M.marinum_M GANAVAQSQAGQTVQSLAAPAAGLLGAPVAQALAAPATGLLGV----PAA
MUL_4594|M.ulcerans_Agy99 ----TVTDQAGQFVQSMAT---------SAWQWADRAR----------QG
TH_2875|M.thermoresistible__bu GG---AAGQAGGFEQMMGMP------------------------------
MSMEG_0069|M.smegmatis_MC2_155 TS-QGGLQGLEQLQQMMQMP------------------------------
MAV_2415|M.avium_104 GPGDPASVPSGGPHEPASVPAEEPREPVSVPAGGVHDPVAEPTGGPHEPA
MAB_1945c|M.abscessus_ATCC_199 RWLKKVGDEVGVDEPLVEVSTDKVDTEIPSPVAGVLLSISANEDDTVAVG
Mflv_0763|M.gilvum_PYR-GCK QMMGMPMQMAQMPMQMMSGIASAPQGLMQGAQQASQQVQQMA----GQFG
Mvan_0082|M.vanbaalenii_PYR-1 QMAG---QMAQMPMQVMGAVAAVPQGIMQGAQQAGQQVQQMV----GQFG
Mb3908|M.bovis_AF2122/97 -VSQVTTQLGETAAELAPRVVATVPQLVQLAPHAVQMSQNAS----PIAQ
Rv3878|M.tuberculosis_H37Rv -VSQVTTQLGETAAELAPRVVATVPQLVQLAPHAVQMSQNAS----PIAQ
MMAR_5453|M.marinum_M AATQIGEAVSAQAEALSPRVAATIPQLVQLAPQAGQMAQQAS----PIAQ
MUL_4594|M.ulcerans_Agy99 VETLI-DQLSPQISEVAAQVAEAGPQLAQLGSQAAFVAQYAS----PMAQ
TH_2875|M.thermoresistible__bu --MQMAQQAAQMPMQMGGMAGQLPQQLAQGAQGAMEQVTQLS----GLAD
MSMEG_0069|M.smegmatis_MC2_155 --MQAVQMAAQVPTQMAQMAAQVPQTVMQGVQQIGQMSGGTG----QDSA
MAV_2415|M.avium_104 SVPAAGSRLASVQAAAGDGLPSATPQLFDHTPSQVPVPAGGSSGEAASVG
MAB_1945c|M.abscessus_ATCC_199 GELAVVGAADAAPAAPAAPAAPAPEPAAAPAAAAAPPAPPAP-----APA
Mflv_0763|M.gilvum_PYR-GCK -QGATGGSASSAAQVPAPDAPAPEP-------------------------
Mvan_0082|M.vanbaalenii_PYR-1 DQGAKDGQKG----TPSGELPTAAN-------------------------
Mb3908|M.bovis_AF2122/97 TISQTAQQAAQSAQGGSGPMPAQLASAEKPATEQAEPVHEVTNDDQGD-Q
Rv3878|M.tuberculosis_H37Rv TISQTAQQAAQSAQGGSGPMPAQLASAEKPATEQAEPVHEVTNDDQGD-Q
MMAR_5453|M.marinum_M TISQSAQQ----GSSQGGAAPAQ-------------LVSDTKPDEDAELA
MUL_4594|M.ulcerans_Agy99 SIGQSTQQIVSTASQAGGAAPAQHG----------LLVDDMKADD----A
TH_2875|M.thermoresistible__bu GDQQGLGD-----DQAGEAVDGVMS-------------------------
MSMEG_0069|M.smegmatis_MC2_155 GPAAPQTDSPVGKSKGGRERDDQQE-------------------------
MAV_2415|M.avium_104 AHSPSSASSAAPHFESPGGRPSEVPAPNGGAHGPGESGPAGGHPPGEPPH
MAB_1945c|M.abscessus_ATCC_199 PAAPAPASTAPAANGAAGDNPYVTPLVRKLAAENNVDLSALSGSGVGGRI
.
Mflv_0763|M.gilvum_PYR-GCK -----ASEGAAAGEPDAERAPTPDERSDRE----DTGAP-GRHRAAEADD
Mvan_0082|M.vanbaalenii_PYR-1 -----REEGAAAAEPHAERAPEPEEKTDTD----GGQRP-GRHRAAESDE
Mb3908|M.bovis_AF2122/97 GDVQPAEVVAAARDEGAGASPGQQPGGGVPAQAMDTGAG-ARPAASPLAA
Rv3878|M.tuberculosis_H37Rv GDVQPAEVVAAARDEGAGASPGQQPGGGVPAQAMDTGAG-ARPAASPLAA
MMAR_5453|M.marinum_M DETKEGEEDAMAAAGAEGAAAGHATLVSAP---VESTGG-GETSTGSVSA
MUL_4594|M.ulcerans_Agy99 DD----ERDAKAGADGAGAAPGSQTLGGAP---IEGGTG-TTADNQSAGP
TH_2875|M.thermoresistible__bu -----EQASAEPESQIPAAVAEQQEQTDQP---GERAPV-GSPSARSAVS
MSMEG_0069|M.smegmatis_MC2_155 -----QHEGAAADPAFTQQAPVTSQVPGAAASEPEAGHSEGRPRANGTVP
MAV_2415|M.avium_104 GGKPSGDGGPPDEDSHRDGTPGNGDDGAAGEIDDGPAGVDGQSTPAKVAG
MAB_1945c|M.abscessus_ATCC_199 RKQDVLAAAEAAKAPAAAPAPAAPAASAPAAVAPSLAHLRGTTQKANRIR
.
Mflv_0763|M.gilvum_PYR-GCK RIDL----------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 RIEL----------------------------------------------
Mb3908|M.bovis_AF2122/97 PVDPSTPAPSTTTTL-----------------------------------
Rv3878|M.tuberculosis_H37Rv PVDPSTPAPSTTTTL-----------------------------------
MMAR_5453|M.marinum_M PI------------------------------------------------
MUL_4594|M.ulcerans_Agy99 DVTVL---------------------------------------------
TH_2875|M.thermoresistible__bu DAEIVL--------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 RPVPSDPAIVL---------------------------------------
MAV_2415|M.avium_104 VDYPLPPSDALRVLEHPGAELQRLADGGVPSSILEGYEPLAGRSVDDFNR
MAB_1945c|M.abscessus_ATCC_199 QITAKKTRESLQETAQLTQTHEVDVTKIAALRARAKAAFAEREGVN----
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 EFTIETSNGERGWDWEAQAPENGFAGNPIESNHIPAGLHFDRIGPNGGGF
MAB_1945c|M.abscessus_ATCC_199 -LTFLPFFAKAAVEALKTHPNVNASYNEESKEITYFDAEHLGIAVDTDQG
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 LSPEGVPLAERATPPGLAAQYHVFEGTGREIPAGKDWVVQHGPAKEAFGQ
MAB_1945c|M.abscessus_ATCC_199 LLSPVIHNAGDLSLAGLARAIADIAARARSGNLKPDELAGGTFTITNIGS
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2415|M.avium_104 PGGGDQWIVLDRATNRPVPVDELIRRRLLREITPPNDKLAIGYRGS----
MAB_1945c|M.abscessus_ATCC_199 QGALFDTPILVPPQAAMLGTGAIVKRPRVIRDDAGNESIGIRSVCYLPLT
Mflv_0763|M.gilvum_PYR-GCK ---------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 ---------------------------------
Mb3908|M.bovis_AF2122/97 ---------------------------------
Rv3878|M.tuberculosis_H37Rv ---------------------------------
MMAR_5453|M.marinum_M ---------------------------------
MUL_4594|M.ulcerans_Agy99 ---------------------------------
TH_2875|M.thermoresistible__bu ---------------------------------
MSMEG_0069|M.smegmatis_MC2_155 ---------------------------------
MAV_2415|M.avium_104 ---------------------------------
MAB_1945c|M.abscessus_ATCC_199 YDHRLIDGADAGRFLTTIKHRLEEGAFEADLGL