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MAEPLAVDPTGLSAAAAKLAGLVFPQPPAPIAVSGTDSVVAAINKTMPSIESLVSDGLPGVKAALTRTAS NMNAAADVYAKTDQSLGTSLSQYAFGSSGEGLAGVASVGGQPSQATQLLSTPVSQVTTQLGETAAELAPR VVATVPQLVQLAPHAVQMSQNASPIAQTISQTAQQAAQSAQGGSGPMPAQLASAEKPATEQAEPVHEVTN DDQGDQGDVQPAEVVAAARDEGAGASPGQQPGGGVPAQAMDTGAGARPAASPLAAPVDPSTPAPSTTTTL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3908 | - | - | 100% (280) | hypothetical protein Mb3908 |
| M. bovis AF2122 / 97 | Mb3469c | - | 4e-06 | 26.40% (250) | hypothetical protein Mb3469c |
| M. bovis AF2122 / 97 | Mb1188c | - | 8e-05 | 28.06% (139) | hypothetical protein Mb1188c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0763 | - | 7e-22 | 33.47% (248) | hypothetical protein Mflv_0763 |
| M. tuberculosis H37Rv | Rv3878 | - | 1e-153 | 99.64% (280) | hypothetical protein Rv3878 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1945c | - | 8e-06 | 23.87% (222) | dihydrolipoamide succinyltransferase |
| M. marinum M | MMAR_5453 | - | 6e-57 | 50.53% (281) | hypothetical protein MMAR_5453 |
| M. avium 104 | MAV_2913 | - | 7e-05 | 25.44% (228) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0069 | - | 1e-10 | 26.69% (251) | translation initiation factor IF-2 protein |
| M. thermoresistible (build 8) | TH_2875 | - | 5e-11 | 26.75% (228) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4594 | - | 1e-43 | 40.29% (273) | hypothetical protein MUL_4594 |
| M. vanbaalenii PYR-1 | Mvan_0082 | - | 2e-18 | 32.65% (245) | hypothetical protein Mvan_0082 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3908|M.bovis_AF2122/97 ------MAEPLAVDPTGLSAAAAKLAG--LVFPQPPAPIAVSGTDSVVAA
Rv3878|M.tuberculosis_H37Rv ------MAEPLAVDPTGLSAAAAKLAG--LVFPQPPAPIAVSGTDSVVAA
MMAR_5453|M.marinum_M ------MAEPLAVDPARLIAAGSKLAE--LVFPAPPAPIAATGGDPVSAA
MUL_4594|M.ulcerans_Agy99 ------MAEPLAVDPAGLGAVGTRLRG--LVFPTPPALIVAAGTDALSVA
Mflv_0763|M.gilvum_PYR-GCK --MVSGGLPPLSVDPTQLSAAGGALKSSALDLPEAPAPFMPVGTDPLSVA
Mvan_0082|M.vanbaalenii_PYR-1 --MATGGTPPLSVDPEELSAAGGALLDSARELPQAPAPFNPVGTDPLSAA
TH_2875|M.thermoresistible__bu ---------LTAAISERITEVVDPVIE---ALPVTKEELKQFAQN--VVS
MSMEG_0069|M.smegmatis_MC2_155 -----------------MEASAR-------AIPEPPDPFKTEGTDPLSKA
MAV_2913|M.avium_104 MSIYAGLPPEVNSARMYSGPGSESMLAAAAAWNALSAELRSAATDYESAI
MAB_1945c|M.abscessus_ATCC_199 ---MAFSVQMPALGESVTEGTVTRWLKQEGDTVEVDEPLLEVSTDKVDTE
: . :
Mb3908|M.bovis_AF2122/97 INKT--------MPSIE------------SLVSDGLPGVKAALTRTASNM
Rv3878|M.tuberculosis_H37Rv INET--------MPSIE------------SLVSDGLPGVKAALTRTASNM
MMAR_5453|M.marinum_M INDT--------MPGIE------------SLVSDGMPGVTAALKRTASSM
MUL_4594|M.ulcerans_Agy99 INTA--------MPNIE------------SSVTDLLPSAKADMANTASSM
Mflv_0763|M.gilvum_PYR-GCK IIGQ--------IPAIE------------TPIATQLPLIKAEATTTASNV
Mvan_0082|M.vanbaalenii_PYR-1 IIGQ--------IPAVE------------APIATQLPLIQAQATSTAQNV
TH_2875|M.thermoresistible__bu AADE--------YDAKD------------RQIAEEILKQIGAFDEPPAHG
MSMEG_0069|M.smegmatis_MC2_155 LADK--------TWQVE------------APFIEGIGKTKAEAQETARRI
MAV_2913|M.avium_104 ATLTGEGWFGPSAAKMS------------AAVTPYLEWLHSTATQAEQAG
MAB_1945c|M.abscessus_ATCC_199 IPAPTSGVLTKIVAREDDTVEIGGELGVISEAGEAAPAAPAPAPAPAAAP
. . .
Mb3908|M.bovis_AF2122/97 NAAADVYAKTDQSLGTSLSQYAFGSSGEGLAGV---ASVGGQPSQATQLL
Rv3878|M.tuberculosis_H37Rv NAAADVYAKTDQSLGTSLSQYAFGSSGEGLAGV---ASVGGQPSQATQLL
MMAR_5453|M.marinum_M STAADIYAKADQALGDALTQYQFGGDGQALGASGANAVAQSQAGQTVQSL
MUL_4594|M.ulcerans_Agy99 ATAADIYTKVDESLGENLSQHQFRGSAPILTGS----TVTDQAGQFVQSM
Mflv_0763|M.gilvum_PYR-GCK EDAAQAYAATDEQNSAAIDQVMQKTPSQMPSGSGG----SAPGGGADAAG
Mvan_0082|M.vanbaalenii_PYR-1 VSAAQVYAETDARNGAAIHEQMQSRLDPLGTGSGGGSLPSTAGGGADSLG
TH_2875|M.thermoresistible__bu GAVPSGGSSAVTGPSSPLSAAGASVGGMTGASVGG---AAGQAGGFEQMM
MSMEG_0069|M.smegmatis_MC2_155 QEAADKYEQSDRTIAENLQSSTGRFDASTGTEGTS-QGGLQGLEQLQQMM
MAV_2913|M.avium_104 AQANAAAAAYQAAFAATVPPAVVAANRTQLANLVAGNIFGQNAGLIAANE
MAB_1945c|M.abscessus_ATCC_199 APEPTPAPAPEATATAAPEPAAEPPAAAAPAGSGTSVKMPELGESVTEGT
Mb3908|M.bovis_AF2122/97 STP---------------------------VSQVTTQLGETAAELAPRVV
Rv3878|M.tuberculosis_H37Rv STP---------------------------VSQVTTQLGETAAELAPRVV
MMAR_5453|M.marinum_M AAPAAGLLGAPVAQALAAPATGLLGVPAAAATQIGEAVSAQAEALSPRVA
MUL_4594|M.ulcerans_Agy99 AT---------SAWQWADRAR------QGVETLI-DQLSPQISEVAAQVA
Mflv_0763|M.gilvum_PYR-GCK QMS--------------------------QMMGMPMQMAQMPMQMMSGIA
Mvan_0082|M.vanbaalenii_PYR-1 MPM--------------------------QMAG---QMAQMPMQVMGAVA
TH_2875|M.thermoresistible__bu GMP----------------------------MQMAQQAAQMPMQMGGMAG
MSMEG_0069|M.smegmatis_MC2_155 QMP----------------------------MQAVQMAAQVPTQMAQMAA
MAV_2913|M.avium_104 AQYG-----------------DMWAQDAAAMTGYASASNAATQQLTPFTP
MAB_1945c|M.abscessus_ATCC_199 VTRWLKKVGDEVGVDEPLVEVSTDKVDTEIPSPVAGVLLSISANEDDTVA
Mb3908|M.bovis_AF2122/97 ATVPQLVQLAPHAVQMSQNASPIAQTISQTAQQAAQSAQGGSGPMPAQLA
Rv3878|M.tuberculosis_H37Rv ATVPQLVQLAPHAVQMSQNASPIAQTISQTAQQAAQSAQGGSGPMPAQLA
MMAR_5453|M.marinum_M ATIPQLVQLAPQAGQMAQQASPIAQTISQSAQQ----GSSQGGAAPAQ--
MUL_4594|M.ulcerans_Agy99 EAGPQLAQLGSQAAFVAQYASPMAQSIGQSTQQIVSTASQAGGAAPAQHG
Mflv_0763|M.gilvum_PYR-GCK SAPQGLMQGAQQASQQVQQMAGQFG-QGATGGSASSAAQVPAPDAPAPEP
Mvan_0082|M.vanbaalenii_PYR-1 AVPQGIMQGAQQAGQQVQQMVGQFGDQGAKDGQKG----TPSGELPTAAN
TH_2875|M.thermoresistible__bu QLPQQLAQGAQGAMEQVTQLSGLADGDQQGLGD-----DQAGEAVDGVMS
MSMEG_0069|M.smegmatis_MC2_155 QVPQTVMQGVQQIGQMSGGTGQDSAGPAAPQTDSPVGKSKGGRERDDQQE
MAV_2913|M.avium_104 PRPDTTANGIAAQANTVAQAANDAGSGDPSGGLLAWLGLAPNTNGPGQPG
MAB_1945c|M.abscessus_ATCC_199 VGGELAVVGAADAAPAAPAAPAAPAPEPAAAPAAAAAPPAPPAPAPAPAA
Mb3908|M.bovis_AF2122/97 SA-----------------------------------------------E
Rv3878|M.tuberculosis_H37Rv SA-----------------------------------------------E
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2913|M.avium_104 LAGLMNFLDGSDGNVLGSFLNNASVANLSNAFTTSGLLNPTSFVDAAVNL
MAB_1945c|M.abscessus_ATCC_199 PAPASTAPAANG-------------------------AAGDNPYVTPLVR
Mb3908|M.bovis_AF2122/97 KPATEQAEPVHEVTNDDQGD-QGDVQPAEVVAAARDEGAGASPGQQPGGG
Rv3878|M.tuberculosis_H37Rv KPATEQAEPVHEVTNDDQGD-QGDVQPAEVVAAARDEGAGASPGQQPGGG
MMAR_5453|M.marinum_M --------LVSDTKPDEDAELADETKEGEEDAMAAAGAEGAAAGHATLVS
MUL_4594|M.ulcerans_Agy99 -------LLVDDMKADD----ADD----ERDAKAGADGAGAAPGSQTLGG
Mflv_0763|M.gilvum_PYR-GCK ---------------------------ASEGAAAGEPDAERAPTPDERSD
Mvan_0082|M.vanbaalenii_PYR-1 ---------------------------REEGAAAAEPHAERAPEPEEKTD
TH_2875|M.thermoresistible__bu ---------------------------EQASAEPESQIPAAVAEQQEQTD
MSMEG_0069|M.smegmatis_MC2_155 ---------------------------QHEGAAADPAFTQQAPVTSQVPG
MAV_2913|M.avium_104 NSINSLNAVDSTTSGLGVLAAGLGGTANLASAAAPGAAAAAEVGQASLVG
MAB_1945c|M.abscessus_ATCC_199 KLAAENNVDLSALSGSGVGGRIRKQDVLAAAEAAKAPAAAPAPAAPAASA
.
Mb3908|M.bovis_AF2122/97 VPAQAMDTGAG-ARPAASPLAAPVDPSTPAPSTTTTL-------------
Rv3878|M.tuberculosis_H37Rv VPAQAMDTGAG-ARPAASPLAAPVDPSTPAPSTTTTL-------------
MMAR_5453|M.marinum_M AP---VESTGG-GETSTGSVSAPI--------------------------
MUL_4594|M.ulcerans_Agy99 AP---IEGGTG-TTADNQSAGPDVTVL-----------------------
Mflv_0763|M.gilvum_PYR-GCK RE----DTGAP-GRHRAAEADDRIDL------------------------
Mvan_0082|M.vanbaalenii_PYR-1 TD----GGQRP-GRHRAAESDERIEL------------------------
TH_2875|M.thermoresistible__bu QP---GERAPV-GSPSARSAVSDAEIVL----------------------
MSMEG_0069|M.smegmatis_MC2_155 AAASEPEAGHSEGRPRANGTVPRPVPSDPAIVL-----------------
MAV_2913|M.avium_104 ALSVPPTWGATGAAITPLAATTQVGLGAYHGFGSATPMVMEEAGAVGMPG
MAB_1945c|M.abscessus_ATCC_199 PAAVAPSLAHLRGTTQKANRIRQITAKKTRESLQETAQLTQTHEVDVTKI
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2913|M.avium_104 VPLAGLPGAHEDEFSEPMYGFRPRIIGRPPAAG-----------------
MAB_1945c|M.abscessus_ATCC_199 AALRARAKAAFAEREGVNLTFLPFFAKAAVEALKTHPNVNASYNEESKEI
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2913|M.avium_104 --------------------------------------------------
MAB_1945c|M.abscessus_ATCC_199 TYFDAEHLGIAVDTDQGLLSPVIHNAGDLSLAGLARAIADIAARARSGNL
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2913|M.avium_104 --------------------------------------------------
MAB_1945c|M.abscessus_ATCC_199 KPDELAGGTFTITNIGSQGALFDTPILVPPQAAMLGTGAIVKRPRVIRDD
Mb3908|M.bovis_AF2122/97 --------------------------------------------------
Rv3878|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5453|M.marinum_M --------------------------------------------------
MUL_4594|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0763|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0082|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2875|M.thermoresistible__bu --------------------------------------------------
MSMEG_0069|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2913|M.avium_104 --------------------------------------------------
MAB_1945c|M.abscessus_ATCC_199 AGNESIGIRSVCYLPLTYDHRLIDGADAGRFLTTIKHRLEEGAFEADLGL